James Dowden

1.2k citations

34 papers · 1.0k indexed · h-index 18

Impact in

Physiology top 2%
- Calcium signaling and nucleotide metabolism
Sensory Systems top 5%

Papers in

Physiology 8
- Calcium signaling and nucleotide metabolism 8
Sensory Systems 3
- Ion Channels and Receptors 3

Co-authors: Stephen G. Ward Jelena Savović Yannis Sotsios Peter M. Finan Ian C. Bruce Wei Hong Anca Pordea Barry V. L. Potter
Journals: Chemical Communications (3 papers)Tetrahedron Letters (3 papers)Organic & Biomolecular Chemistry (3 papers)Biochemical Journal (2 papers)Angewandte Chemie International Edition (2 papers)
Partner nations: United Kingdom United States Singapore

In The Last Decade

James Dowden

33 papers receiving 984 citations

Peers

Replace Roland Feifel with:

Roland Feifel Switzerland

Robert Aslanian United States

Ralph A. Rivero United States

Woan-Ru Shieh United States

Werngard Czechtizky Germany

Fabrizio Bordi Italy

Paul Beswick United Kingdom

Neng‐Yang Shih United States

Nicole D. Barth United Kingdom

Toshio Izawa Japan

James Dowden relative to Roland Feifel Switzerland Roland Feifel's profile →

Citations per field

00.5×2×4×6×7.6×

Roland Feifel · 1×

×7.6 190/25

PHYSI

×4.6 78/17

SS

×1.2 418/338

OC

×0.6 437/769

MB

×2.6 57/22

CB

Citations per year

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Countries citing papers authored by James Dowden

Since Specialization

Citations

This map shows the geographic impact of James Dowden's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Dowden with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Dowden more than expected).

Fields of papers citing papers by James Dowden

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Dowden. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Dowden. The network helps show where James Dowden may publish in the future.

Co-authorship network

The 25 scholars most cited alongside James Dowden, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James Dowden Line = papers co-authored together James Dowden links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4) Biochemical Journal ·Ballav Niroula, Saman Galali, B. Simpson, Clare C. Davies, James Dowden, Ingrid Dreveny	2020	14
2	Stereoselective Synthesis of Tetrahydroindolizines through the Catalytic Formation of Pyridinium Ylides from Diazo Compounds Angewandte Chemie International Edition ·Patrik Myrestam, Igor Baboľ, James Dowden	2016	69
3	Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides Organic & Biomolecular Chemistry ·Patrik Myrestam, Maliha Uroos, Farhan Manzoor Ahmed Khan, William Lewis, Igor Baboľ, James Dowden	2013	35
4	An unusual silicon mediated transannular cyclopropanation Chemical Communications ·Bui Hoang Khuong, Тараканов Павел Витальевич, William Lewis, James Dowden	2012	4
5	Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1 Organic & Biomolecular Chemistry ·James Dowden, Yassir Rochd, Richard V. Parry, Wei Hong, B. Simpson, Stephen G. Ward	2011	32
6	Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases Bioorganic & Medicinal Chemistry Letters ·James Dowden, Wei Hong, Richard V. Parry, Yassir Rochd, Stephen G. Ward	2010	58
7	NAADP-mediated Ca ²⁺ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist Proceedings of the National Academy of Sciences ·Werner Dammermann, Jorge Agrimbau, Есипов А.С., Chiara Cordiglieri, Francesca Odoardi, Tanja Kirchberger, Naoto Kawakami, James Dowden, Ling-Bo Yi, Klaus Dornmair, M. Hohenegger, Alexander Flügel, Andreas H. Guse, Barry V. L. Potter	2009	88
8	Cell-permeant NAADP: A novel chemical tool enabling the study of Ca2+ signalling in intact cells Cell Calcium ·Raman Parkesh, Alexander M. Lewis, Parvinder K. Aley, Abdelilah Arredouani, Sara Rossi, 竜太古川, Sridhar R. Vasudevan, D. Ratajczak, (unknown), James Dowden, Grant C. Churchill	2007	61
9	Novel octavalent cross-linker displays efficient trapping of protein–protein interactions Chemical Communications ·Simon R. Foster, Szymaska, Alexander J. Blake, Melanie J. Welham, James Dowden	2007	1
10	Chemical genetics suggests a critical role for lysyl oxidase in zebrafish notochord morphogenesis Molecular BioSystems ·Carrie L. Anderson, 樊耀星, John M. Gansner, Duncan Wilson, Ling He, Jonathan D. Gitlin, Robert N. Kelsh, James Dowden	2006	56
11	Cell-Permeant Small-Molecule Modulators of NAADP-Mediated Ca2+ Release Chemistry & Biology ·James Dowden, G. Berridge, Christelle Moreau, Michiko Yamasaki, Grant C. Churchill, Barry V. L. Potter, (unknown)	2006	13
12	Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP⁺) Organic & Biomolecular Chemistry ·Raman Parkesh, Sridhar R. Vasudevan, A.J. Berry, (unknown), James Dowden, Grant C. Churchill	2006	5
13	Caged-Iron Chelators a Novel Approach towards Protecting Skin Cells against UVA-Induced Necrotic Cell Death Journal of Investigative Dermatology ·Anthie Yiakouvaki, Jelena Savović, Виталий Новиков, James Dowden, Charareh Pourzand	2006	34
14	CHEMICAL SYNTHESIS OF THE NOVEL CA²⁺ MESSENGER NAADP Nucleosides Nucleotides & Nucleic Acids ·James Dowden, Monica Marchino, Christelle Moreau, (unknown), Barry V. L. Potter	2005	6
15	Chemical Synthesis of the Second Messenger Nicotinic Acid Adenine Dinucleotide Phosphate by Total Synthesis of Nicotinamide Adenine Dinucleotide Phosphate Angewandte Chemie International Edition ·James Dowden, Christelle Moreau, Monica Marchino, G. Berridge, (unknown), Barry V. L. Potter	2004	20
16	The NAADP receptor: commentary on Billington et al. British Journal of Pharmacology ·(unknown), John Parrington, James Dowden	2004	6
17	Therapeutic Potential of Phosphoinositide 3-Kinase Inhibitors Chemistry & Biology ·Stephen G. Ward, Yannis Sotsios, James Dowden, Ian C. Bruce, Peter M. Finan	2003	112
18	New Drugs: Modafinil Australian Prescriber ·James Dowden, (unknown), (unknown), (unknown), (unknown), (unknown)	2002	0
19	Inhibitors of p56lck: assessing their potential as tools for manipulating T-lymphocyte activation Expert Opinion on Therapeutic Patents ·James Dowden, Stephen G. Ward	2001	10
20	Novel Mechanism of Inhibition of Elastase by β-Lactams Is Defined by Two Inhibitor Crystal Complexes Journal of Biological Chemistry ·Paul Taylor, Ingrid García Torres, Malcolm D. Walkinshaw, James Dowden, Sabine L. Flitsch, Nicholas J. Turner, Kopp Cw	1999	12

About James Dowden

James Dowden is a scholar working on Physiology, Sensory Systems, Organic Chemistry, Pharmacology and Molecular Biology, having authored 34 papers that have together received 1.0k indexed citations. Recurring topics across this work include Calcium signaling and nucleotide metabolism (8 papers), Cyclopropane Reaction Mechanisms (5 papers), Chemical Synthesis and Analysis (5 papers), Synthesis and Reactivity of Heterocycles (4 papers), Cancer-related gene regulation (4 papers), Epigenetics and DNA Methylation (4 papers), Catalytic C–H Functionalization Methods (3 papers) and Ion Channels and Receptors (3 papers). The work is most often cited by research in Physiology (190 citations), Sensory Systems (78 citations), Organic Chemistry (418 citations), Molecular Biology (437 citations) and Cell Biology (57 citations). James Dowden has collaborated with scholars based in United Kingdom, United States and Singapore. Frequent co-authors include Stephen G. Ward, Jelena Savović, Yannis Sotsios, Peter M. Finan, Ian C. Bruce, Wei Hong, Anca Pordea, Barry V. L. Potter, Richard V. Parry and Varinder K. Aggarwal. Their work appears in journals such as Chemical Communications, Tetrahedron Letters, Organic & Biomolecular Chemistry, Biochemical Journal and Angewandte Chemie International Edition.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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