Jeffrey C. Kern

1.0k total citations
17 papers, 511 citations indexed

About

Jeffrey C. Kern is a scholar working on Genetics, Organic Chemistry and Molecular Biology. According to data from OpenAlex, Jeffrey C. Kern has authored 17 papers receiving a total of 511 indexed citations (citations by other indexed papers that have themselves been cited), including 8 papers in Genetics, 7 papers in Organic Chemistry and 7 papers in Molecular Biology. Recurrent topics in Jeffrey C. Kern's work include Estrogen and related hormone effects (8 papers), Bioactive Compounds and Antitumor Agents (4 papers) and Synthesis and Reactions of Organic Compounds (4 papers). Jeffrey C. Kern is often cited by papers focused on Estrogen and related hormone effects (8 papers), Bioactive Compounds and Antitumor Agents (4 papers) and Synthesis and Reactions of Organic Compounds (4 papers). Jeffrey C. Kern collaborates with scholars based in United States, Canada and Austria. Jeffrey C. Kern's co-authors include Puwen Zhang, Zhiming Zhang, Richard C. Winneker, Andrew Fensome, Yuan Zhu, Jay Wrobel, Eugene A. Terefenko, Jeffrey Cohen, Matthew R. Yudt and Eugene J. Trybulski and has published in prestigious journals such as Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and European Journal of Cancer.

In The Last Decade

Jeffrey C. Kern

16 papers receiving 500 citations

Peers

Jeffrey C. Kern
F. Nique France
Donna Wei United States
Peter F. Bousquet United States
Jeffrey C. Kern
Citations per year, relative to Jeffrey C. Kern Jeffrey C. Kern (= 1×) peers Shuichi Mori

Countries citing papers authored by Jeffrey C. Kern

Since Specialization
Citations

This map shows the geographic impact of Jeffrey C. Kern's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeffrey C. Kern with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeffrey C. Kern more than expected).

Fields of papers citing papers by Jeffrey C. Kern

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeffrey C. Kern. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeffrey C. Kern. The network helps show where Jeffrey C. Kern may publish in the future.

Co-authorship network of co-authors of Jeffrey C. Kern

This figure shows the co-authorship network connecting the top 25 collaborators of Jeffrey C. Kern. A scholar is included among the top collaborators of Jeffrey C. Kern based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jeffrey C. Kern. Jeffrey C. Kern is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

17 of 17 papers shown
1.
Smith, Sean M., Dawn Toolan, Monika Kandebo, et al.. (2024). Preclinical evaluation of MK-8189: A novel phosphodiesterase 10A inhibitor for the treatment of schizophrenia. Journal of Pharmacology and Experimental Therapeutics. 392(1). 100047–100047. 1 indexed citations
2.
Layton, M. E., Jeffrey C. Kern, William D. Shipe, et al.. (2023). Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia. Journal of Medicinal Chemistry. 66(2). 1157–1171. 22 indexed citations
3.
Gamerith, Gabriele, Hubert Hackl, Jeffrey C. Kern, et al.. (2018). Soluble immune checkpoints CD27, Lag3, PD-L2 and Tim3 in early stage NSCLC patients. European Journal of Cancer. 92. S12–S12. 1 indexed citations
4.
Kern, Jeffrey C., Rena Zhang, Linda Liang, et al.. (2016). Novel Phosphate Modified Cathepsin B Linkers: Improving Aqueous Solubility and Enhancing Payload Scope of ADCs. Bioconjugate Chemistry. 27(9). 2081–2088. 64 indexed citations
5.
Bruno, Tullia C., Peggy J. Ebner, Brandon Moore, et al.. (2015). Antigen presentation by tumor infiltrating B cells influences CD4 T cell phenotype and function in primary lung cancer patient tumors. Journal for ImmunoTherapy of Cancer. 3(S2).
6.
Gilbert, A., Matthew G. Bursavich, Sabrina Lombardi, et al.. (2010). 3-(Pyridin-2-yl-ethynyl)benzamide metabotropic glutamate receptor 5 negative allosteric modulators: Hit to lead studies. Bioorganic & Medicinal Chemistry Letters. 21(1). 195–199. 3 indexed citations
7.
Crombie, Aimee L., David L. Crandall, Amedeo Failli, et al.. (2010). Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists. Bioorganic & Medicinal Chemistry Letters. 20(12). 3742–3745. 25 indexed citations
8.
Kern, Jeffrey C., Eugene A. Terefenko, Eugene J. Trybulski, et al.. (2010). 1-Methyl-1H-pyrrole-2-carbonitrile containing tetrahydronaphthalene derivatives as non-steroidal progesterone receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 20(16). 4816–4818. 9 indexed citations
9.
Moore, William, Jeffrey C. Kern, Ramesh A. Bhat, et al.. (2009). Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: Part II. Bioorganic & Medicinal Chemistry. 18(1). 190–201. 18 indexed citations
10.
Kern, Jeffrey C., Eugene A. Terefenko, Eugene J. Trybulski, et al.. (2009). 5-Aryl indanones and derivatives as non-steroidal progesterone receptor modulators. Bioorganic & Medicinal Chemistry Letters. 19(23). 6666–6669. 10 indexed citations
11.
Kern, Jeffrey C., Eugene A. Terefenko, Andrew Fensome, et al.. (2008). 1,5-Dihydro-benzo[e][1,4]oxazepin-2(1H)-ones containing a 7-(5′-cyanopyrrol-2-yl) group as nonsteroidal progesterone receptor modulators. Bioorganic & Medicinal Chemistry Letters. 18(18). 5015–5017. 4 indexed citations
12.
Zhang, Puwen, Jeffrey C. Kern, Eugene A. Terefenko, et al.. (2008). 7-Aryl 1,5-dihydro-benzo[e][1,4]oxazepin-2-ones and analogs as non-steroidal progesterone receptor antagonists. Bioorganic & Medicinal Chemistry. 16(13). 6589–6600. 16 indexed citations
13.
Fensome, Andrew, William R. Adams, Christine Huselton, et al.. (2008). Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348). Journal of Medicinal Chemistry. 51(6). 1861–1873. 184 indexed citations
14.
Moore, William, Jeffrey C. Kern, Ramesh A. Bhat, et al.. (2008). Modulation of Wnt Signaling Through Inhibition of Secreted Frizzled-Related Protein I (sFRP-1) with N-Substituted Piperidinyl Diphenylsulfonyl Sulfonamides. Journal of Medicinal Chemistry. 52(1). 105–116. 47 indexed citations
15.
Zhang, Puwen, Eugene A. Terefenko, Jeffrey C. Kern, et al.. (2007). 5-(3-Cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile: A novel, highly potent, selective, and orally active non-steroidal progesterone receptor agonist. Bioorganic & Medicinal Chemistry. 15(20). 6556–6564. 18 indexed citations
16.
Kern, Jeffrey C., Eugene A. Terefenko, Andrew Fensome, et al.. (2006). SAR studies of 6-(arylamino)-4,4-disubstituted-1-methyl-1,4-dihydro-benzo[d][1,3]oxazin-2-ones as progesterone receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 17(1). 189–192. 37 indexed citations
17.
Terefenko, Eugene A., Jeffrey C. Kern, Andrew Fensome, et al.. (2005). SAR studies of 6-aryl-1,3-dihydrobenzimidazol-2-ones as progesterone receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 15(15). 3600–3603. 52 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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