Isaac A. Chaim

2.4k total citations · 1 hit paper
15 papers, 1.3k citations indexed

About

Isaac A. Chaim is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Oncology. According to data from OpenAlex, Isaac A. Chaim has authored 15 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 3 papers in Cellular and Molecular Neuroscience and 2 papers in Oncology. Recurrent topics in Isaac A. Chaim's work include DNA Repair Mechanisms (7 papers), RNA Research and Splicing (5 papers) and Epigenetics and DNA Methylation (2 papers). Isaac A. Chaim is often cited by papers focused on DNA Repair Mechanisms (7 papers), RNA Research and Splicing (5 papers) and Epigenetics and DNA Methylation (2 papers). Isaac A. Chaim collaborates with scholars based in United States, India and Singapore. Isaac A. Chaim's co-authors include G Yeo, Leona D. Samson, Zachary D. Nagel, Wei Wu, Alain Domissy, Bradley Voytek, Priscilla D. Negraes, Allen Wang, Gabriel G. Haddad and Matthieu Vandenberghe and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Isaac A. Chaim

15 papers receiving 1.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development

2019 538 citations Cleber A. Trujillo, Richard Gao et al. Cell stem cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Isaac A. Chaim United States	13	977	275	206	164	140	15	1.3k
Wun Chey Sin Canada	18	1000 1.0×	490 1.8×	162 0.8×	130 0.8×	102 0.7×	25	1.5k
Stefano Giannetti Italy	24	491 0.5×	223 0.8×	251 1.2×	115 0.7×	264 1.9×	40	1.3k
Amanda J. Kedaigle United States	11	865 0.9×	243 0.9×	58 0.3×	269 1.6×	73 0.5×	14	1.3k
Elizabeth A. Stoll United Kingdom	15	943 1.0×	198 0.7×	358 1.7×	102 0.6×	85 0.6×	30	1.8k
Silvia Velasco United States	12	944 1.0×	197 0.7×	54 0.3×	279 1.7×	66 0.5×	18	1.3k
Kevin C. Ess United States	27	1.2k 1.2×	325 1.2×	84 0.4×	129 0.8×	119 0.8×	59	2.2k
Yuejun Chen China	20	968 1.0×	520 1.9×	48 0.2×	203 1.2×	111 0.8×	45	1.4k
Daniel Gyllborg Sweden	13	1.0k 1.1×	231 0.8×	131 0.6×	60 0.4×	49 0.3×	15	1.3k
Angela Bithell United Kingdom	16	985 1.0×	431 1.6×	138 0.7×	138 0.8×	38 0.3×	27	1.4k
Devin Chandler-Militello United States	16	1.3k 1.3×	486 1.8×	226 1.1×	116 0.7×	57 0.4×	22	1.9k

Countries citing papers authored by Isaac A. Chaim

Since Specialization

Citations

This map shows the geographic impact of Isaac A. Chaim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isaac A. Chaim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isaac A. Chaim more than expected).

Fields of papers citing papers by Isaac A. Chaim

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isaac A. Chaim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isaac A. Chaim. The network helps show where Isaac A. Chaim may publish in the future.

Co-authorship network of co-authors of Isaac A. Chaim

This figure shows the co-authorship network connecting the top 25 collaborators of Isaac A. Chaim. A scholar is included among the top collaborators of Isaac A. Chaim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isaac A. Chaim. Isaac A. Chaim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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15 of 15 papers shown

Madrigal, Assael A., et al.. (2024). Mapping the future of oxidative RNA damage in neurodegeneration: Rethinking the status quo with new tools. Proceedings of the National Academy of Sciences. 121(46). e2317860121–e2317860121. 9 indexed citations

Morelli, Kathryn H., Wenhao Jin, Assael A. Madrigal, et al.. (2022). MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy. Science Translational Medicine. 14(651). eabn2375–eabn2375. 15 indexed citations

Brannan, Kristopher W., Isaac A. Chaim, Ryan J. Marina, et al.. (2021). Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes. Nature Methods. 18(5). 507–519. 87 indexed citations

Chaim, Isaac A., Patrizia Mazzucato, Catherine Ricciardi, et al.. (2021). CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage. Free Radical Biology and Medicine. 174. 89–99. 14 indexed citations

Einstein, Jaclyn M., Mark Perelis, Isaac A. Chaim, et al.. (2021). Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer. Molecular Cell. 81(15). 3048–3064.e9. 119 indexed citations

Trujillo, Cleber A., Richard Gao, Priscilla D. Negraes, et al.. (2019). Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. Cell stem cell. 25(4). 558–569.e7. 538 indexed citations breakdown →

Chaim, Isaac A., et al.. (2018). Nitric oxide induced S-nitrosation causes base excision repair imbalance. DNA repair. 68. 25–33. 17 indexed citations

Batra, Ranjan, David A. Nelles, Elaine Pirie, et al.. (2017). Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9. Cell. 170(5). 899–912.e10. 191 indexed citations

Chaim, Isaac A., Alycia Gardner, Jie Wu, et al.. (2017). A novel role for transcription-coupled nucleotide excision repair for thein vivorepair of 3,N⁴-ethenocytosine. Nucleic Acids Research. 45(6). gkx015–gkx015. 14 indexed citations

10.

Margulies, Carrie M., et al.. (2017). Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms. PLoS ONE. 12(9). e0184619–e0184619. 5 indexed citations

11.

Chaim, Isaac A., et al.. (2017). In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities. Proceedings of the National Academy of Sciences. 114(48). E10379–E10388. 45 indexed citations

12.

Nagel, Zachary D., Gaspar J. Kitange, Shiv K. Gupta, et al.. (2016). DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme. Cancer Research. 77(1). 198–206. 102 indexed citations

13.

Nagel, Zachary D., Carrie M. Margulies, Isaac A. Chaim, et al.. (2014). Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis. Proceedings of the National Academy of Sciences. 111(18). E1823–32. 105 indexed citations

14.

Nagel, Zachary D., Isaac A. Chaim, & Leona D. Samson. (2014). Inter-individual variation in DNA repair capacity: A need for multi-pathway functional assays to promote translational DNA repair research. DNA repair. 19. 199–213. 53 indexed citations

15.

Chaim, Isaac A., et al.. (2011). Evaluation of the potential of novel PCL-PPDX biodegradable scaffolds as support materials for cartilage tissue engineering. Journal of Tissue Engineering and Regenerative Medicine. 6(4). 272–279. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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