Thomas F. Westbrook

14.4k citations

41 papers · 5.9k indexed · 4 hit papers · h-index 28

Molecular Biology top 1%
Cancer Research top 1%
Oncology top 2%
Pulmonary and Respiratory Medicine top 2%
Genetics top 5%

Co-authors: Stephen J. Elledge Michael R. Schlabach Ji Luo Kwok‐Kin Wong Chad J. Creighton Michael J. Emanuele Danan Li Don X. Nguyen
Topics: Epigenetics and DNA Methylation (8 papers)RNA modifications and cancer (7 papers)Cancer-related gene regulation (6 papers)
Cited by: Cancer Research Molecular Biology Oncology
Journals: Nature Science Cell
Partner nations: United States Canada China

In The Last Decade

Thomas F. Westbrook

40 papers receiving 5.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Energy-stress-mediated AMPK activation inhibits ferroptosis

2020 851 citations Hyemin Lee, Fereshteh Zandkarimi et al. Nature Cell Biology profile →
A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

2009 779 citations Ji Luo, Michael R. Schlabach et al. Cell profile →
A resource for large-scale RNA-interference-based screens in mammals

2004 554 citations Mamie Z. Li, Kenneth Chang et al. Nature Cell Biology profile →
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

2011 473 citations Kristen L. Meerbrey, Guang Hu et al. profile →

Peers

Countries citing papers authored by Thomas F. Westbrook

Since Specialization

Citations

This map shows the geographic impact of Thomas F. Westbrook's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas F. Westbrook with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas F. Westbrook more than expected).

Fields of papers citing papers by Thomas F. Westbrook

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas F. Westbrook. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas F. Westbrook. The network helps show where Thomas F. Westbrook may publish in the future.

Co-authorship network of co-authors of Thomas F. Westbrook

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas F. Westbrook. A scholar is included among the top collaborators of Thomas F. Westbrook based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas F. Westbrook. Thomas F. Westbrook is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Bio-primed machine learning to enhance discovery of relevant biomarkers 2025 ·npj Precision Oncology ·David Henke,Alexander Renwick,(unknown),Jitendra K. Meena,Nicholas J. Neill,(unknown),Kristen L. Meerbrey,Thomas F. Westbrook,Lukas M. Simon	4
2	Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation 2022 ·eLife ·Wesley L. Cai,(unknown),Huacui Chen,(unknown),Sarah J. Kurley,Lok-Hei Chan,Meiling Zhang,Anna Arnal Estape,Minghui Zhao,(unknown),Wenxue Li,Xufen Yu,(unknown),Yali Dou,Yansheng Liu,Jian Jin,Thomas F. Westbrook,Don X. Nguyen,Qin Yan	14
3	Tumor Suppressor PLK2 May Serve as a Biomarker in Triple-Negative Breast Cancer for Improved Response to PLK1 Therapeutics 2021 ·Cancer Research Communications ·Yang Gao,Elena B. Kabotyanski,Jonathan H. Shepherd,(unknown),(unknown),(unknown),Tingting Sun,(unknown),Xiaping He,Lacey E. Dobrolecki,Thomas F. Westbrook,Michael T. Lewis,Susan G. Hilsenbeck,Xiang H.-F. Zhang,Charles M. Perou,Jeffrey M. Rosen	8
4	Energy-stress-mediated AMPK activation inhibits ferroptosisbreakdown → 2020 ·Nature Cell Biology ·Hyemin Lee,Fereshteh Zandkarimi,Yilei Zhang,Jitendra K. Meena,Jongchan Kim,Li Zhuang,Siddhartha Tyagi,Li Ma,Thomas F. Westbrook,Gregory R. Steinberg,Daisuke Nakada,Brent R. Stockwell,Boyi Gan	851
5	Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy 2019 ·Cell Reports ·(unknown),Salendra Singh,Jarey H. Wang,Jonathan Rennhack,(unknown),Virginie Sanguin‐Gendreau,Dongmei Zuo,(unknown),Cynthia Lavoie,Morag Park,Eran R. Andrechek,Thomas F. Westbrook,Lyndsay N. Harris,Vinay Varadan,Harvey W. Smith,William J. Muller	29
6	A molecular portrait of epithelial–mesenchymal plasticity in prostate cancer associated with clinical outcome 2018 ·Oncogene ·Nataly Stylianou,Melanie Lehman,Chenwei Wang,Atefeh Taherian Fard,Anja Rockstroh,Ladan Fazli,Lidija Jovanovic,Micheal Ward,Martin C. Sadowski,Abhishek S. Kashyap,Ralph Buttyan,Martin Gleave,Thomas F. Westbrook,Elizabeth D. Williams,Jennifer H. Gunter,Colleen C. Nelson,Brett G. Hollier	79
7	Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma 2018 ·Nature Genetics ·Rhamy Zeid,Matthew A. Lawlor,Evon Poon,Jaime M. Reyes,Mariateresa Fulciniti,Michael Lopez,Thomas G. Scott,Behnam Nabet,Michael A. Erb,Georg E. Winter,(unknown),(unknown),Kristen L. Karlin,Rachel Hirsch,Nikhil Munshi,Thomas F. Westbrook,Louis Chesler,Charles Y. Lin,James E. Bradner	129
8	Loss of De Novo DNA Methyltransferase DNMT3A Impacts Alternative Splicing in Hematopoietic Stem Cells 2017 ·Blood ·(unknown),Jarey H. Wang,Anna Guzman,Sean M. Cullen,Lorenzo Brunetti,Michael C. Gundry,Sunny Sun-Kin Chan,Michael Kyba,Thomas F. Westbrook,Margaret A. Goodell	11
9	Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model 2016 ·Neuron ·Cristian A. Lasagna‐Reeves,María de Haro,Shuang Hao,Jeehye Park,Maxime W.C. Rousseaux,Ismael Al‐Ramahi,Paymaan Jafar‐Nejad,(unknown),Lauren See,Antonia De Maio,Larissa Nitschke,(unknown),Juan C. Troncoso,Thomas F. Westbrook,Jianrong Tang,Juan Botas,Huda Y. Zoghbi	107
10	TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau 2016 ·eLife ·Maxime W.C. Rousseaux,María de Haro,Cristian A. Lasagna‐Reeves,Antonia De Maio,Jeehye Park,Paymaan Jafar‐Nejad,Ismael Al‐Ramahi,Ajay Sharma,Lauren See,Nan Lü,(unknown),Tiemo J. Klisch,Thomas F. Westbrook,Juan C. Troncoso,Juan Botas,Huda Y. Zoghbi	81
11	The Osteogenic Niche Promotes Early-Stage Bone Colonization of Disseminated Breast Cancer Cells 2015 ·Cancer Cell ·Hai Wang,C. Ron Yu,Xia Gao,Thomas Welte,Aaron M. Muscarella,Lin Tian,Hong Zhao,Zhen Zhao,Shiyu Du,Jianning Tao,Brendan Lee,Thomas F. Westbrook,Stephen T.C. Wong,Xin Jin,Jeffrey M. Rosen,C. Kent Osborne,Xiang H.-F. Zhang	272
12	A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors 2015 ·Cell Reports ·Lior Izhar,Britt Adamson,Alberto Ciccia,(unknown),(unknown),Yumei Leng,Anthony C. Liang,Thomas F. Westbrook,J. Wade Harper,Stephen J. Elledge	129
13	Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2 2014 ·Nature Communications ·Qi Miao,Amy T. Ku,(unknown),Jeffrey Howard,(unknown),Timothy M. Shaver,(unknown),(unknown),Kristen L. Karlin,Thomas F. Westbrook,Valeria Poli,Hoang Nguyen	55
14	A role for PVRL4-driven cell-cell interactions in tumorigenesis 2013 ·DSpace@MIT (Massachusetts Institute of Technology) ·Christian P. Pallasch,Christian Braun,Michael T. Hemann,Natalya N. Pavlova,Andrew E. H. Elia,Thomas F. Westbrook,Stephen J. Elledge	3
15	Control of Alveolar Differentiation by the Lineage Transcription Factors GATA6 and HOPX Inhibits Lung Adenocarcinoma Metastasis 2013 ·Cancer Cell ·William K.C. Cheung,Minghui Zhao,Zongzhi Liu,(unknown),Paul D. Cao,Justin E. Fang,Thomas F. Westbrook,Don X. Nguyen	107
16	An Animal Model of MYC-Driven Medulloblastoma 2012 ·Cancer Cell ·Yanxin Pei,Colin E. Moore,Jun Wang,Alok K. Tewari,Alexey M. Eroshkin,Yoon-Jae Cho,Hendrik Witt,Andrey Korshunov,Tracy‐Ann Read,Julia Sun,Earlene M. Schmitt,C. Ryan Miller,Anne F. Buckley,Roger E. McLendon,Thomas F. Westbrook,Paul A. Northcott,Michael D. Taylor,Stefan M. Pfister,Phillip G. Febbo,Robert J. Wechsler‐Reya	211
17	Cancer Proliferation Gene Discovery Through Functional Genomics 2008 ·Science ·Michael R. Schlabach,Ji Luo,Nicole L. Solimini,Guang Hu,Qikai Xu,Mamie Z. Li,Zhenming Zhao,Agata Smogorzewska,Mathew E. Sowa,Xiaolu L. Ang,Thomas F. Westbrook,Anthony C. Liang,Kenneth Chang,(unknown),J. Wade Harper,Gregory J. Hannon,Stephen J. Elledge	291
18	SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation 2008 ·Nature ·Thomas F. Westbrook,Guang Hu,Xiaolu L. Ang,Peter Mulligan,Natalya N. Pavlova,Anthony C. Liang,Yumei Leng,René Maehr,Yang Shi,J. Wade Harper,Stephen J. Elledge	251
19	CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation 2008 ·Molecular Cell ·Peter Mulligan,Thomas F. Westbrook,Matthias Ottinger,Natalya N. Pavlova,Bin Chang,Eric Macia,(unknown),Jordi Barretina,Jinsong Liu,Peter M. Howley,Stephen J. Elledge,Yang Shi	122
20	A Genetic Screen for Candidate Tumor Suppressors Identifies REST 2005 ·Cell ·Thomas F. Westbrook,Eric S. Martin,Michael R. Schlabach,Yumei Leng,Anthony C. Liang,Bin Feng,Jean J. Zhao,Thomas M. Roberts,Gail Mandel,Gregory J. Hannon,Ronald A. DePinho,Lynda Chin,Stephen J. Elledge	390

About Thomas F. Westbrook

Thomas F. Westbrook is a scholar working on Cell Biology, Molecular Biology and Cancer Research, having authored 41 papers that have together received 5.9k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (8 papers), RNA modifications and cancer (7 papers) and Cancer-related gene regulation (6 papers). The work is most often cited by research in Cancer Research (1.5k citations), Molecular Biology (4.4k citations) and Oncology (1.4k citations). Thomas F. Westbrook has collaborated with scholars based in United States, Canada and China. Frequent co-authors include Stephen J. Elledge, Michael R. Schlabach, Ji Luo, Kwok‐Kin Wong, Chad J. Creighton, Michael J. Emanuele, Danan Li, Don X. Nguyen, Anthony C. Liang and Mamie Z. Li. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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