Ira D. Goldfine

25.6k citations

279 papers · 20.5k indexed · 5 hit papers · h-index 67

Molecular Biology top 0.2%
Endocrinology, Diabetes and Metabolism top 0.05%
Surgery top 0.2%
Physiology top 0.5%
Cellular and Molecular Neuroscience top 0.5%

Co-authors: Betty A. Maddux Joseph L. Evans John A. Williams Gerold M. Grodsky Riccardo Vigneri Rodger A. Liddle Jack Youngren Antonio Brunetti
Topics: Metabolism, Diabetes, and Cancer (107 papers)Pancreatic function and diabetes (88 papers)Growth Hormone and Insulin-like Growth Factors (50 papers)
Cited by: Endocrinology, Diabetes and Metabolism Molecular Biology Physiology
Journals: Nature Science Cell
Partner nations: United States Italy United Kingdom

In The Last Decade

Ira D. Goldfine

277 papers receiving 19.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes

2002 1.8k citations Joseph L. Evans, Ira D. Goldfine et al. profile →
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 1.3k citations Ira D. Goldfine et al. profile →
Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction?

2003 1.2k citations Joseph L. Evans, Ira D. Goldfine et al. profile →
Insulin Receptor Isoform A, a Newly Recognized, High-Affinity Insulin-Like Growth Factor II Receptor in Fetal and Cancer Cells

1999 724 citations Francesco Frasca, Giuseppe Pandini et al. Molecular and Cellular Biology profile →
Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction.

1985 593 citations Ira D. Goldfine, John A. Williams et al. Journal of Clinical Investigation profile →

Peers

Countries citing papers authored by Ira D. Goldfine

Since Specialization

Citations

This map shows the geographic impact of Ira D. Goldfine's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ira D. Goldfine with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ira D. Goldfine more than expected).

Fields of papers citing papers by Ira D. Goldfine

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ira D. Goldfine. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ira D. Goldfine. The network helps show where Ira D. Goldfine may publish in the future.

Co-authorship network of co-authors of Ira D. Goldfine

This figure shows the co-authorship network connecting the top 25 collaborators of Ira D. Goldfine. A scholar is included among the top collaborators of Ira D. Goldfine based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ira D. Goldfine. Ira D. Goldfine is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Attenuation of Insulin Action by an Allosteric Insulin Receptor Antibody in Healthy Volunteers 2017 ·The Journal of Clinical Endocrinology & Metabolism ·Kirk W. Johnson,(unknown),Allan Gordon,(unknown),(unknown),(unknown),Ira D. Goldfine,Paul Rubin	12
2	Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle 2011 ·PLoS ONE ·Umesh Masharani,Betty A. Maddux,Xiaojuan Li,Giorgos K. Sakkas,Kathleen Mulligan,Morris Schambelan,Ira D. Goldfine,Jack Youngren	50
3	Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF‐1 receptor tyrosine kinases, blocks the growth of HER2‐overexpressing human breast cancer cells 2007 ·Journal of Cellular Biochemistry ·Marianna Zavodovskaya,Michael J. Campbell,Betty A. Maddux,Laura Shiry,Geoffrey Allan,Leslie Hodges-Gallagher,Peter J. Kushner,John A. Kerner,Jack Youngren,Ira D. Goldfine	42
4	Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T 2007 ·Magnetic Resonance Imaging ·Xiaojuan Li,Jack Youngren,(unknown),Giorgos K. Sakkas,Kathleen Mulligan,Sharmila Majumdar,Umesh Masharani,Morris Schambelan,Ira D. Goldfine	25
5	IGF-Binding Protein-1 Levels Are Related to Insulin-Mediated Glucose Disposal and Are a Potential Serum Marker of Insulin Resistance 2006 ·Diabetes Care ·Betty A. Maddux,(unknown),Lawrence J. Mandarino,Ira D. Goldfine,Elena A. De Filippis	56
6	Novel Approach to Treat Insulin Resistance, Type 2 Diabetes, and the Metabolic Syndrome: Simultaneous Activation of PPARα, PPARγ, and PPARδ 2005 ·Current Diabetes Reviews ·Joseph L. Evans,Jack J. Lin,Ira D. Goldfine	46
7	Insulin Receptor Isoform A, a Newly Recognized, High-Affinity Insulin-Like Growth Factor II Receptor in Fetal and Cancer Cellsbreakdown → 1999 ·Molecular and Cellular Biology ·Francesco Frasca,Giuseppe Pandini,Pierluigi Scalia,Laura Sciacca,Rossana Mineo,Angela Costantino,Ira D. Goldfine,Antonino Belfiore,Riccardo Vigneri	724
8	The insulin receptor content is increased in breast cancers initiated by three different oncogenes in transgenic mice 1997 ·Breast Cancer Research and Treatment ·Lucia Frittitta,Aniello Cerrato,(unknown),Noel Weidner,Ira D. Goldfine,Riccardo Vigneri	26
9	Identification of unique nuclear regulatory proteins for the insulin receptor gene, which appear during myocyte and adipocyte differentiation. 1993 ·Journal of Clinical Investigation ·Antonio Brunetti,Daniela Foti,Ira D. Goldfine	38
10	Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification 1993 ·Biochemistry ·Junko Kasuya,I. Benjamin Paz,Betty A. Maddux,Ira D. Goldfine,Stanley A. Hefta,(unknown)	63
11	High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells. 1992 ·Journal of Clinical Investigation ·G Milazzo,Christopher Yip,Betty A. Maddux,Riccardo Vigneri,Ira D. Goldfine	35
12	Binding of mutant insulins to a mutated insulin receptor 1992 ·Biochemical and Biophysical Research Communications ·Ronit Rafaeloff,Cecil C. Yip,Ira D. Goldfine	3
13	Cloning and Characterization of the Human Insulin-Like Growth Factor-I Receptor Gene 5′-Flanking Region 1992 ·DNA and Cell Biology ·(unknown),Ira D. Goldfine	37
14	Radioimmunoassay for human insulin-like growth factor-I receptor: Applicability to breast carcinoma specimens and cell lines 1991 ·Metabolism ·V. Pezzino,Giovanni Milazzo,Lucia Frittitta,Riccardo Vigneri,Osamu Ezaki,(unknown),Thomas LeBon,Ira D. Goldfine,(unknown)	8
15	Elevated insulin receptor content in human breast cancer. 1990 ·Journal of Clinical Investigation ·Vincenzo Papa,V. Pezzino,Angela Costantino,Antonino Belfiore,Dario Giuffrida,Lucia Frittitta,G. B. Vannelli,Randall E. Brand,Ira D. Goldfine,Riccardo Vigneri	273
16	Localization of the insulin-binding site to the cysteine-rich region of the insulin receptor α-subunit 1988 ·Biochemical and Biophysical Research Communications ·Cecil C. Yip,(unknown),(unknown),Dennis M. Hawley,Betty A. Maddux,Ira D. Goldfine	65
17	Do insulin and the insulin like growth factors (IGFs) stimulate growth of the exocrine pancreas? 1987 ·Gut ·Joachim Mössner,Craig D. Logsdon,Ira D. Goldfine,John A. Williams	24
18	Receptors for Insulin and CCK in the Acinar Pancreas: Relationship to Hormone Action 1983 ·International review of cytology ·Ira D. Goldfine,John A. Williams	23
19	Insulin and glucagon receptors in Morris hepatomas of varying growth rates. 1979 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·V. Pezzino,Riccardo Vigneri,Marvin D. Siperstein,Ira D. Goldfine	18
20	Insulin receptors in isolated mouse pancreatic acini 1978 ·Biochemical and Biophysical Research Communications ·Murray Korc,H. Sankaran,K. Y. Wong,John A. Williams,Ira D. Goldfine	46

About Ira D. Goldfine

Ira D. Goldfine is a scholar working on Endocrinology, Diabetes and Metabolism, Molecular Biology and Surgery, having authored 279 papers that have together received 20.5k indexed citations. Recurring topics across this work include Metabolism, Diabetes, and Cancer (107 papers), Pancreatic function and diabetes (88 papers) and Growth Hormone and Insulin-like Growth Factors (50 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (6.9k citations), Molecular Biology (10.5k citations) and Physiology (3.6k citations). Ira D. Goldfine has collaborated with scholars based in United States, Italy and United Kingdom. Frequent co-authors include Betty A. Maddux, Joseph L. Evans, John A. Williams, Gerold M. Grodsky, Riccardo Vigneri, Rodger A. Liddle, Jack Youngren, Antonio Brunetti, H. Sankaran and Antonino Belfiore. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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