I‐hung Shih

7.8k total citations · 2 hit papers
18 papers, 6.3k citations indexed

About

I‐hung Shih is a scholar working on Molecular Biology, Hepatology and Infectious Diseases. According to data from OpenAlex, I‐hung Shih has authored 18 papers receiving a total of 6.3k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 12 papers in Hepatology and 7 papers in Infectious Diseases. Recurrent topics in I‐hung Shih's work include Hepatitis C virus research (12 papers), HIV/AIDS drug development and treatment (7 papers) and RNA and protein synthesis mechanisms (6 papers). I‐hung Shih is often cited by papers focused on Hepatitis C virus research (12 papers), HIV/AIDS drug development and treatment (7 papers) and RNA and protein synthesis mechanisms (6 papers). I‐hung Shih collaborates with scholars based in United States, Czechia and Belgium. I‐hung Shih's co-authors include David P. Bartel, Matthew W. Jones-Rhoades, Christopher B. Burge, Benjamin P. Lewis, Soraya Yekta, Michael D. Been, Anne T. Perrotta, Eric Mabery, Richard L. Mackman and Michal Hocek and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

I‐hung Shih

18 papers receiving 6.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Prediction of Mammalian MicroRNA Targets

2003 4.2k citations Benjamin P. Lewis, I‐hung Shih et al. Cell profile →
MicroRNA-Directed Cleavage of HOXB8 mRNA

2004 1.4k citations Soraya Yekta, I‐hung Shih et al. Science profile →

Peers

Countries citing papers authored by I‐hung Shih

Since Specialization

Citations

This map shows the geographic impact of I‐hung Shih's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by I‐hung Shih with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites I‐hung Shih more than expected).

Fields of papers citing papers by I‐hung Shih

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by I‐hung Shih. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by I‐hung Shih. The network helps show where I‐hung Shih may publish in the future.

Co-authorship network of co-authors of I‐hung Shih

This figure shows the co-authorship network connecting the top 25 collaborators of I‐hung Shih. A scholar is included among the top collaborators of I‐hung Shih based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with I‐hung Shih. I‐hung Shih is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

#	Work	Indexed citations
1	Evaluation of 2′-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase 2013 ·Bioorganic & Medicinal Chemistry Letters ·Jay P. Parrish, (unknown), Constantine G. Boojamra, Hon C. Hui, Darius Babusis, Brandon Brown, I‐hung Shih, Joy Y. Feng, Adrian S. Ray, Richard L. Mackman	7
2	Optimized High-Throughput Screen for Hepatitis C Virus Translation Inhibitors 2011 ·SLAS DISCOVERY ·Katherine E. Berry, Betty Peng, David Koditek, (unknown), Nikos Pagratis, Jason K. Perry, Jay P. Parrish, Weidong Zhong, Jennifer A. Doudna, I‐hung Shih	8
3	In Vitro Combination Therapy with Tegobuvir (GS-9190) is Highly Efficient in Curing Cells from HCV Replicon and in Delaying/Preventing the Development of Antiviral Resistance 2011 ·Antiviral Research ·Inge Vliegen, Jan Paeshuyse, I‐hung Shih, Gerhard Pürstinger, Steven Bondy, William A. Lee, Weidong Zhong, Johan Neyts	1
4	Comparison of HCV NS3 protease and NS5B polymerase inhibitor activity in 1a, 1b and 2a replicons and 2a infectious virus 2009 ·Antiviral Research ·Matthew Paulson, Huiling Yang, I‐hung Shih, Joy Y. Feng, Eric Mabery, Margaret Robinson, Weidong Zhong, William E. Delaney	18
5	Substituted imidazopyridines as potent inhibitors of HCV replication 2009 ·Journal of Hepatology ·Inge Vliegen, Jan Paeshuyse, Tine De Burghgraeve, Laura S. Lehman, Matthew Paulson, I‐hung Shih, Eric Mabery, (unknown), Erik De Clercq, Hans Reiser, (unknown), William A. Lee, Weidong Zhong, Steven Bondy, Gerhard Pürstinger, Johan Neyts	35
6	Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides 2007 ·Bioorganic & Medicinal Chemistry ·Martin Kuchař, Michal Hocek, Radek Pohl, Ivan Votruba, I‐hung Shih, Eric Mabery, Richard L. Mackman	16
7	Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides 2007 ·Bioorganic & Medicinal Chemistry ·Peter Šilhár, Michal Hocek, Radek Pohl, Ivan Votruba, I‐hung Shih, Eric Mabery, Richard L. Mackman	21
8	GS-9190, a novel substituted imidazo-pyridine analogue, is a potent inhibitor of hepatitis C virus replication in vitro and remains active against known drug-resistant mutants 2007 ·Inge Vliegen, Jan Paeshuyse, Eric Mabery, Betty Peng, I‐hung Shih, Laura S. Lehman, Hélène Dutartre, Barbara Selisko, Bruno Canard, Steven Bondy, Winston C. Tse, Hans Reiser, Erik De Clercq, William A. Lee, Gerhard Puerstinger, Weidong Zhong, Johan Neyts	8
9	Purines Bearing Phenanthroline or Bipyridine Ligands and Their Ru^II Complexes in Position 8 as Model Compounds for Electrochemical DNA Labeling – Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antiviral Activity 2007 ·European Journal of Inorganic Chemistry ·Milan Vrábel, Michal Hocek, Luděk Havran, Miroslav Fojta, Ivan Votruba, Blanka Klepetářová, Radek Pohl, Lubomı́r Rulı́šek, (unknown), Pavel Hobza, I‐hung Shih, Eric Mabery, Richard L. Mackman	45
10	Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine l-ribonucleosides 2006 ·Bioorganic & Medicinal Chemistry Letters ·Michal Hocek, Peter Šilhár, I‐hung Shih, Eric Mabery, Richard L. Mackman	39
11	MicroRNA-Directed Cleavage of HOXB8 mRNA breakdown → 2004 ·Science ·Soraya Yekta, I‐hung Shih, David P. Bartel	1369
12	Prediction of Mammalian MicroRNA Targets breakdown → 2003 ·Cell ·Benjamin P. Lewis, I‐hung Shih, Matthew W. Jones-Rhoades, David P. Bartel, Christopher B. Burge	4156
13	Catalytic Strategies of the Hepatitis Delta Virus Ribozymes 2002 ·Annual Review of Biochemistry ·I‐hung Shih, Michael D. Been	85
14	A pH-sensitive RNA tertiary interaction affects self-cleavage activity of the HDV ribozymes in the absence of added divalent metal ion 2001 ·Journal of Molecular Biology ·(unknown), I‐hung Shih, Anne T. Perrotta, Michael D. Been	71
15	Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage 2001 ·Proceedings of the National Academy of Sciences ·I‐hung Shih, Michael D. Been	74
16	Kinetic Scheme for Intermolecular RNA Cleavage by a Ribozyme Derived from Hepatitis Delta Virus RNA 2000 ·Biochemistry ·I‐hung Shih, Michael D. Been	32
17	Ribozyme cleavage of a 2′,5′-phosphodiester linkage: Mechanism and a restricted divalent metal-ion requirement 1999 ·RNA ·I‐hung Shih, Michael D. Been	38
18	Imidazole Rescue of a Cytosine Mutation in a Self-Cleaving Ribozyme 1999 ·Science ·Anne T. Perrotta, I‐hung Shih, Michael D. Been	230

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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