I. Byrjalsen

7.2k citations

143 papers · 5.6k indexed · 2 hit papers · h-index 42

Molecular Biology top 5%
Rheumatology top 0.5%
Oncology top 2%
Orthopedics and Sports Medicine top 0.5%
Endocrinology, Diabetes and Metabolism top 1%

Co-authors: Claus Christiansen M.A. Karsdal Peter Alexandersen Anne‐Christine Bay‐Jensen Diana Julie Leeming Per Qvist Kim Henriksen Asger Reinstrup Bihlet
Topics: Osteoarthritis Treatment and Mechanisms (43 papers)Inflammatory mediators and NSAID effects (23 papers)Rheumatoid Arthritis Research and Therapies (20 papers)
Cited by: Rheumatology Orthopedics and Sports Medicine Endocrinology, Diabetes and Metabolism
Journals: JAMA Journal of Biological Chemistry Circulation
Partner nations: Denmark United States Germany

In The Last Decade

I. Byrjalsen

141 papers receiving 5.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Collagenolytic Activity of Cathepsin K Is Unique among Mammalian Proteinases

1998 518 citations Patrick Garnero, Olivier Borel et al. Journal of Biological Chemistry profile →
Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis

2019 242 citations Marc C. Hochberg, Hans Guehring et al. profile →

Peers

Countries citing papers authored by I. Byrjalsen

Since Specialization

Citations

This map shows the geographic impact of I. Byrjalsen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by I. Byrjalsen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites I. Byrjalsen more than expected).

Fields of papers citing papers by I. Byrjalsen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by I. Byrjalsen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by I. Byrjalsen. The network helps show where I. Byrjalsen may publish in the future.

Co-authorship network of co-authors of I. Byrjalsen

This figure shows the co-authorship network connecting the top 25 collaborators of I. Byrjalsen. A scholar is included among the top collaborators of I. Byrjalsen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with I. Byrjalsen. I. Byrjalsen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The efficacy and safety of a fixed-dose combination of apocynin and paeonol, APPA, in symptomatic knee OA: A double-blind, randomized, placebo-controlled, clinical trial 2024 ·Osteoarthritis and Cartilage ·Asger Reinstrup Bihlet,I. Byrjalsen,J.R. Andersen,Alan Reynolds,(unknown),Peter Alexandersen,(unknown),Robert J. Moots,Philip G. Conaghan	7
2	Impact of monitoring approaches on data quality in clinical trials 2022 ·British Journal of Clinical Pharmacology ·J.R. Andersen,(unknown),I. Byrjalsen,(unknown),(unknown),Asger Reinstrup Bihlet	3
3	A low cartilage formation and repair endotype predicts radiographic progression of symptomatic knee osteoarthritis 2021 ·Journal of Orthopaedics and Traumatology ·Yunyun Luo,Jonathan Samuels,Svetlana Krasnokutsky,I. Byrjalsen,Virginia B. Kraus,Yi He,M.A. Karsdal,Steven B. Abramson,Mukundan Attur,Anne‐Christine Bay‐Jensen	31
4	Long-term efficacy and safety of intra-articular sprifermin in patients with knee osteoarthritis: results from the 5-year forward study 2020 ·Osteoarthritis and Cartilage ·F. Eckstein,Marc C. Hochberg,(unknown),Hans Guehring,Flavie Moreau,Victor Ona,Asger Reinstrup Bihlet,I. Byrjalsen,J.R. Andersen,(unknown),(unknown),C. Ladel,M. Michaelis,Philip G. Conaghan	3
5	SAT0634 CO-MORBIDITIES ASSOCIATED WITH DISCORDANCE BETWEEN STRUCTURAL SEVERITY AND PAIN IN OSTEOARTHRITIS: IMPLICATIONS FOR CLINICAL TRIAL DESIGN IN OA – A POST-HOC ANALYSIS OF DATA FROM TWO RANDOMIZED CONTROLLED TRIALS 2019 ·Annals of the Rheumatic Diseases ·(unknown),I. Byrjalsen,M.A. Karsdal,J.R. Andersen,Asger Reinstrup Bihlet	1
6	Biomarkers of bone and cartilage turnover CTX-I and CTX-II predict total joint replacements in osteoarthritis 2019 ·Osteoarthritis and Cartilage ·(unknown),Anne‐Christine Bay‐Jensen,M.A. Karsdal,I. Byrjalsen,J.R. Andersen,B.J. Riis,Claus Christiansen,Asger Reinstrup Bihlet	6
7	Segregating OA patients with and without joint inflammation using two biomarkers of connective tissue inflammation 2015 ·Osteoarthritis and Cartilage ·Anne‐Christine Bay‐Jensen,I. Byrjalsen,Asger Reinstrup Bihlet,(unknown),B.J. Riis,Claus Christiansen,M.A. Karsdal	1
8	Association between joint space width, Kellgren-Lawrence score, pain and progression in osteoarthritis subjects from two phase III studies – a clinical study reference database 2014 ·Osteoarthritis and Cartilage ·Peter Alexandersen,I. Byrjalsen,Anne‐Christine Bay‐Jensen,(unknown),J.R. Andersen,B.J. Riis,(unknown),M.A. Karsdal	0
9	Two novel diagnostic biomarkers of cartilage degradation and connective tissue inflammation are predictive of radiographic disease progression 2012 ·Osteoarthritis and Cartilage ·Anne‐Christine Bay‐Jensen,Stephanie Wichuk,I. Byrjalsen,M.A. Karsdal,Walter P. Maksymowych	1
10	Human macrophage foam cells degrade atherosclerotic plaques through cathepsin K mediated processes 2010 ·BMC Cardiovascular Disorders ·Natasha Barascuk,Helene Skjøt‐Arkil,Thomas C. Register,Lise Larsen,I. Byrjalsen,Claus Christiansen,M.A. Karsdal	38
11	PLCL1 rs7595412 variation is not associated with hip bone size variation in postmenopausal Danish women 2009 ·BMC Medical Genetics ·Stéphane Cauchi,I. Byrjalsen,Emmanuelle Durand,M.A. Karsdal,Philippe Froguel	2
12	Does increased local bone resorption secondary to breast and prostate cancer result in increased cartilage degradation? 2008 ·BMC Cancer ·Diana Julie Leeming,I. Byrjalsen,Per Qvist,Mitsuru Koizumi,Niels Lynnerup,(unknown),Mette G Sørensen,Claus Christiansen,M.A. Karsdal	3
13	The influence of smoking on uterine bleeding during continuous and interrupted oral hormone therapy 2007 ·Climacteric ·N. H. Bjarnason,Henrik L. Jørgensen,I. Byrjalsen,Peter Alexandersen,Claus Christiansen	3
14	Bone turnover and bone collagen maturation in osteoporosis: effects of antiresorptive therapies 2007 ·Osteoporosis International ·I. Byrjalsen,Diana Julie Leeming,Per Qvist,Claus Christiansen,M.A. Karsdal	57
15	Anabolic and catabolic function of chondrocyte ex vivo is reflected by the metabolic processing of type II collagen 2006 ·Osteoarthritis and Cartilage ·Ann‐Karin Olsen,B.C. Søndergaard,I. Byrjalsen,László B. Tankó,Claus Christiansen,Andreas J. Müller,Gert Hein,M.A. Karsdal,Per Qvist	39
16	Matrix metalloproteinase-12 (MMP-12) in osteoclasts: new lesson on the involvement of MMPs in bone resorption 2003 ·Bone ·Hou Peng,(unknown),(unknown),Tove Kirkegaard,Thomas Levin Andersen,I. Byrjalsen,Mercedes Ferreras,Takuya Sato,Steven D. Shapiro,Niels T. Foged,Jean‐Marie Delaissé	84
17	Raloxifene and estrogen reduces progression of advanced atherosclerosis — a study in ovariectomized, cholesterol-fed rabbits 2001 ·Atherosclerosis ·Nina Hannover Bjarnason,Jens Haarbo,I. Byrjalsen,Peter Alexandersen,Raymond F. Kauffman,Claus Christiansen	28
18	The Collagenolytic Activity of Cathepsin K Is Unique among Mammalian Proteinasesbreakdown → 1998 ·Journal of Biological Chemistry ·Patrick Garnero,Olivier Borel,I. Byrjalsen,Mercedes Ferreras,Fred H. Drake,Michael S. McQueney,Niels T. Foged,Pierre D. Delmas,Jean‐Marie Delaissé	518
19	Serum placental protein 14 (PP14) reflects endometrial status during hormone replacement therapy 1992 ·Human Reproduction ·I. Byrjalsen,(unknown),B. Meinecke,B.J. Riis,Claus Christiansen	14
20	The measurement of secretory endometrial protein PP14 in serum from postmenopausal women receiving unopposed estrogen or continuously combined estrogen/ progestogen 1989 ·Gynecological Endocrinology ·I. Byrjalsen,B.J. Riis,Claus Christiansen	12

About I. Byrjalsen

I. Byrjalsen is a scholar working on Rheumatology, Orthopedics and Sports Medicine and Pharmacology, having authored 143 papers that have together received 5.6k indexed citations. Recurring topics across this work include Osteoarthritis Treatment and Mechanisms (43 papers), Inflammatory mediators and NSAID effects (23 papers) and Rheumatoid Arthritis Research and Therapies (20 papers). The work is most often cited by research in Rheumatology (1.7k citations), Orthopedics and Sports Medicine (928 citations) and Endocrinology, Diabetes and Metabolism (870 citations). I. Byrjalsen has collaborated with scholars based in Denmark, United States and Germany. Frequent co-authors include Claus Christiansen, M.A. Karsdal, Peter Alexandersen, Anne‐Christine Bay‐Jensen, Diana Julie Leeming, Per Qvist, Kim Henriksen, Asger Reinstrup Bihlet, Jens Haarbo and Pierre D. Delmas. Their work appears in journals such as JAMA, Journal of Biological Chemistry and Circulation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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