Hyuk Woo Lee

1.7k citations

43 papers · 1.2k indexed · h-index 21

Physiology top 0.5%
- Adenosine and Purinergic Signaling 21
Toxicology top 5%
Organic Chemistry top 10%
- Synthesis and Biological Evaluation 7
Molecular Biology top 10%
- Biochemical and Molecular Research 10
- Pharmacological Receptor Mechanisms and Effects 9
- Ubiquitin and proteasome pathways 6
- DNA and Nucleic Acid Chemistry 3
Infectious Diseases top 10%
- HIV/AIDS drug development and treatment 9
Psychiatry and Mental health
- Bipolar Disorder and Treatment 4

Co-authors: Lak Shin Jeong Hea Ok Kim Won Jun Choi Sang Kook Lee Kenneth A. Jacobson Zhan‐Guo Gao Dilip K. Tosh Hyung Ryong Moon
Cited by: Physiology Toxicology Organic Chemistry
Journals: Journal of Medicinal Chemistry (11 papers)Archives of Pharmacal Research (4 papers)Bioorganic & Medicinal Chemistry (4 papers)
Partner nations: South Korea United States China

In The Last Decade

Hyuk Woo Lee

41 papers receiving 1.2k citations

Peers

Countries citing papers authored by Hyuk Woo Lee

Since Specialization

Citations

This map shows the geographic impact of Hyuk Woo Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hyuk Woo Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hyuk Woo Lee more than expected).

Fields of papers citing papers by Hyuk Woo Lee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hyuk Woo Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hyuk Woo Lee. The network helps show where Hyuk Woo Lee may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Hyuk Woo Lee, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hyuk Woo Lee Line = papers co-authored together Hyuk Woo Lee links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structure–Activity Relationships of Truncated 1′-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs Journal of Medicinal Chemistry ·Bernadine Fernz,Seungchan An,Odoemene Simon Nnayere,Г.Л. Муравьева,V. M. Chandrshekar,Rongguang Pan,A Sutera,Gyudong Kim,Albiona Beselica Beha,Hyuk Woo Lee,Minsoo Noh,Joo Young Huh,Sun Choi,Hong‐Rae Kim,Lak Shin Jeong	2023	4
2	Structure–Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A_2A/A₃ Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity Journal of Medicinal Chemistry ·Y. P. Du,Xiyan Hou,Woong Sub Byun,Gyudong Kim,Dnyandev B. Jarhad,Chen Lu,Bernadine Fernz,Jinha Yu,Chang‐Soo Lee,Xiaoqian Li,Chihaya Kiyomitsu,Zhan‐Guo Gao,Ji Yong Kim,Tabah Ghifary Diniya,Hyun‐Woo Shin,William Jesús Valdez-Pazos,Kenneth A. Jacobson,Hyuk Woo Lee,Sang Kook Lee,Lak Shin Jeong	2023	12
3	In Silico Discovery of 5′-Modified 7-Deoxy-7-ethynyl-4′-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor ACS Central Science ·Eun‐Ji Kwon,和仁桂,Ju‐Hee Seo,Dong-Yang Li,寛平岡,Paul J. Mackey,Olivia Clifton,Haeseung Lee,Hyuk Woo Lee,Gyudong Kim,Byung Woo Han,Sang Kook Lee,Lak Shin Jeong,Hyuk‐Jin Cha	2023	3
4	Discovery of a Novel Template, 7-Substituted 7-Deaza-4′-Thioadenosine Derivatives as Multi-Kinase Inhibitors Pharmaceuticals ·和仁桂,Woong Sub Byun,Hyejin Ko,寛平岡,Sushil Tripathi,Seungchan An,保吉芹澤,B.Z. Katzenellenbaum,Odoemene Simon Nnayere,Y. P. Du,Eun‐Ji Kwon,Hyuk Woo Lee,Minsoo Noh,Sang Kook Lee,Lak Shin Jeong	2021	7
5	Design, Synthesis, and Anti-RNA Virus Activity of 6′-Fluorinated-Aristeromycin Analogues Journal of Medicinal Chemistry ·健史山岸,Gyudong Kim,Dnyandev B. Jarhad,Hong‐Rae Kim,赵云路,Xiaoqian Li,Pramod K. Sahu,Hea Ok Kim,Hyuk Woo Lee,Pimphak Thaweewong,晴善青木,Tong‐Shin Chang,Natacha S. Ogando,Kristína Kováčiková,Eric J. Snijder,Clara C. Posthuma,Martijn J. van Hemert,Lak Shin Jeong	2019	41
6	N⁶-Substituted 5′-N-Methylcarbamoyl-4′-selenoadenosines as Potent and Selective A₃ Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation Journal of Medicinal Chemistry ·Jinha Yu,Long Zhao,Aleksander Osadchiev,Hyuk Woo Lee,Pramod K. Sahu,Minghua Cui,Steven M. Moss,Е.А. Гасаненко,Chihaya Kiyomitsu,Zhan-Guo Gao,Minsoo Noh,Sun Choi,Hee‐Chul Ahn,Jung‐Won Choi,Kenneth A. Jacobson,Lak Shin Jeong	2017	21
7	Structure–activity relationships of 2′-modified-4′-selenoarabinofuranosyl-pyrimidines as anticancer agents European Journal of Medicinal Chemistry ·Jinhee Kim,Jinha Yu,Varughese Alexander,Su Hyun LEE,Jayoung Song,Hyuk Woo Lee,Hea Ok Kim,Jung‐Won Choi,Sang Kook Lee,Lak Shin Jeong	2014	20
8	c-Cbl-Mediated Neddylation Antagonizes Ubiquitination and Degradation of the TGF-β Type II Receptor Molecular Cell ·Wei Zuo,Fei Huang,Y. Jeffrey Chiang,Meng Li,Jun Du,Yi Ding,Ting Zhang,Hyuk Woo Lee,Lak Shin Jeong,Yuling Chen,Haiteng Deng,Xin‐Hua Feng,Shiwen Luo,Chunji Gao,(unknown),(unknown)	2013	127
9	Neddylation pathway regulates the proliferation and survival of macrophages Biochemical and Biophysical Research Communications ·Lihui Li,Binghong Liu,M. Adachi,Hyuk Woo Lee,Jinha Yu,Yijie Zheng,Haifeng Gao,Yan Zhang,Yiwei Chu,Guangwei Liu,Weixin Niu,Zheng Shi-min,Lak Shin Jeong,Lijun Jia	2013	42
10	The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth Cancer Research ·Zhongguang Luo,Guangyang Yu,Hyuk Woo Lee,Lihui Li,Lingyan Wang,Dongqin Yang,Yongfu Pan,Chan Ding,Jing Qian,Lijun Wu,Yiwei Chu,Jing Yi,Xiangdong Wang,Yi Sun,Lak Shin Jeong,Jie Liu,Lijun Jia	2012	202
11	Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621 Archives of Pharmacal Research ·Girish Chandra,Varughese Alexander,Hyuk Woo Lee,Lak Shin Jeong	2012	7
12	A3 Adenosine Receptor Agonist Reduces Brain Ischemic Injury and Inhibits Inflammatory Cell Migration in Rats American Journal Of Pathology ·In Young Choi,Jae‐Chul Lee,Chung Ju,Sun‐Young Hwang,Geum-Sil Cho,Hyuk Woo Lee,Won Jun Choi,Lak Shin Jeong,Won-Ki Kim	2011	67
13	Design and synthesis of N6-substituted-4′-thioadenosine-5′-uronamides as potent and selective human A3 adenosine receptor agonists Bioorganic & Medicinal Chemistry ·Won Jun Choi,Hyuk Woo Lee,Hea Ok Kim,韩耀兰,Zhan‐Guo Gao,Amit R. Patel,Kenneth A. Jacobson,Hyung Ryong Moon,Young Hoon Jung,Lak Shin Jeong	2009	14
14	Structure–activity relationships of 2-chloro-N6-substituted-4′-thioadenosine-5′-N,N-dialkyluronamides as human A3 adenosine receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Lak Shin Jeong,Hyuk Woo Lee,Hea Ok Kim,Dilip K. Tosh,Shantanu Pal,Won Jun Choi,Zhan‐Guo Gao,Amit R. Patel,Kunkun Zeng,Kenneth A. Jacobson,Hee‐Doo Kim	2008	13
15	Design, Synthesis, and Anti-Tumor Activity of 4′-Thionucleosides as Potent and Selective Agonists at the Human A₃Adenosine Receptor Nucleosides Nucleotides & Nucleic Acids ·Lak Shin Jeong,Hyuk Woo Lee,Hea Ok Kim,Ji Young Jung,Prashantha Gunaga,Sang Kook Lee,Eun‐Jin Lee,Moon Woo Chun,Zhan‐Guo Gao,Kenneth A. Jacobson,Hyung Ryong Moon	2007	0
16	Alternative and improved syntheses of highly potent and selective A3 adenosine receptor agonists, CI-IB-MECA and Thio-CI-IB-MECA Archives of Pharmacal Research ·Xiyan Hou,Hyuk Woo Lee,Dilip K. Tosh,Long Zhao,Lak Shin Jeong	2007	4
17	Design, synthesis, and biological activity of N6-substituted-4′-thioadenosines at the human A3 adenosine receptor Bioorganic & Medicinal Chemistry ·Lak Shin Jeong,Hyuk Woo Lee,Hea Ok Kim,Ji Young Jung,Zhan‐Guo Gao,Heng T. Duong,Juha Venho,Kenneth A. Jacobson,Dae Hong Shin,FACR Ritsuko U. Komaki,Prashantha Gunaga,Sang Kook Lee,E Campos Rodríguez,Moon Woo Chun,Hyung Ryong Moon	2006	20
18	Stereoselective Functionalization of the 1‘-Position of 4‘-Thionucleosides Organic Letters ·Prashantha Gunaga,Hea Ok Kim,Hyuk Woo Lee,Dilip K. Tosh,Borisov Nikolai,Sun Choi,Lak Shin Jeong	2006	8
19	Conversion of A3 adenosine receptor agonists into selective antagonists by modification of the 5′-ribofuran-uronamide moiety Bioorganic & Medicinal Chemistry Letters ·Zhan‐Guo Gao,Bhalchandra V. Joshi,Athena M. Klutz,Soo‐Kyung Kim,Hyuk Woo Lee,Hea Ok Kim,Lak Shin Jeong,Kenneth A. Jacobson	2005	30
20	Synthesis of (−)-neplanocin A analogues as potential antiviral agents Archives of Pharmacal Research ·Dae Hong Shin,Hyuk Woo Lee,Sung Soo Park,Joong Hyup Kim,Lak Shin Jeong,Moon Woo Chun	2000	4

About Hyuk Woo Lee

Hyuk Woo Lee is a scholar working on Physiology, Infectious Diseases and Molecular Biology, having authored 43 papers that have together received 1.2k indexed citations. Recurring topics across this work include Adenosine and Purinergic Signaling (21 papers), Biochemical and Molecular Research (10 papers), Pharmacological Receptor Mechanisms and Effects (9 papers), HIV/AIDS drug development and treatment (9 papers), Synthesis and Biological Evaluation (7 papers), Ubiquitin and proteasome pathways (6 papers), Bipolar Disorder and Treatment (4 papers) and DNA and Nucleic Acid Chemistry (3 papers). The work is most often cited by research in Physiology (370 citations), Toxicology (52 citations) and Organic Chemistry (317 citations). Hyuk Woo Lee has collaborated with scholars based in South Korea, United States and China. Frequent co-authors include Lak Shin Jeong, Hea Ok Kim, Won Jun Choi, Sang Kook Lee, Kenneth A. Jacobson, Zhan‐Guo Gao, Dilip K. Tosh, Hyung Ryong Moon, Varughese Alexander and Lijun Jia. Their work appears in journals such as Journal of Medicinal Chemistry, Archives of Pharmacal Research, Bioorganic & Medicinal Chemistry, Nucleosides Nucleotides & Nucleic Acids and Organic Letters.

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