Hitoshi Nagaoka

5.4k citations

70 papers · 4.4k indexed · 2 hit papers · h-index 33

Immunology top 0.5%
Molecular Biology top 5%
Radiology, Nuclear Medicine and Imaging top 2%
Oncology top 5%
Epidemiology top 5%

Co-authors: Tasuku Honjo Masamichi Muramatsu Kazuo Kinoshita Reiko Shinkura Nasim A. Begum Sidonia Fagarasan Keiichiro Suzuki Michel C. Nussenzweig
Topics: T-cell and B-cell Immunology (27 papers)Immune Cell Function and Interaction (18 papers)Cytomegalovirus and herpesvirus research (9 papers)
Cited by: Immunology Genetics Molecular Biology
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: Japan United States United Kingdom

In The Last Decade

Hitoshi Nagaoka

69 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Critical Roles of Activation-Induced Cytidine Deaminase in the Homeostasis of Gut Flora

2002 474 citations Masamichi Muramatsu, Hitoshi Nagaoka et al. Science profile →
Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locus

1993 276 citations Fumihiko Matsuda, Euy Kyun Shin et al. Nature Genetics profile →

Peers

Countries citing papers authored by Hitoshi Nagaoka

Since Specialization

Citations

This map shows the geographic impact of Hitoshi Nagaoka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hitoshi Nagaoka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hitoshi Nagaoka more than expected).

Fields of papers citing papers by Hitoshi Nagaoka

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hitoshi Nagaoka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hitoshi Nagaoka. The network helps show where Hitoshi Nagaoka may publish in the future.

Co-authorship network of co-authors of Hitoshi Nagaoka

This figure shows the co-authorship network connecting the top 25 collaborators of Hitoshi Nagaoka. A scholar is included among the top collaborators of Hitoshi Nagaoka based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hitoshi Nagaoka. Hitoshi Nagaoka is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Regulation of RHOV signaling by interaction with SH3 domain-containing adaptor proteins and phosphorylation by PKA 2024 ·Biochemical and Biophysical Research Communications ·(unknown),Takuya Ito,Shun Nakano,(unknown),Katsuya Sato,Masashi Nishikawa,Katsuyuki Nakamura,Hitoshi Nagaoka,Takahiro Nagase,Hiroshi Ueda	0
2	The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells 2019 ·Cellular Signalling ·Masashi Nishikawa,Shun Nakano,(unknown),Katsuya Sato,Tsuyoshi Sugiyama,Yukihiro Akao,Hitoshi Nagaoka,Hisashi Yamakawa,Takahiro Nagase,Hiroshi Ueda	6
3	DBS is activated by EPHB2/SRC signaling-mediated tyrosine phosphorylation in HEK293 cells 2019 ·Molecular and Cellular Biochemistry ·Shun Nakano,Masashi Nishikawa,(unknown),(unknown),(unknown),Katsuya Sato,Hitoshi Nagaoka,Hisashi Yamakawa,Takahiro Nagase,Hiroshi Ueda	4
4	The circulating immunoglobulins negatively impact on the parasite clearance in the liver of Leishmania donovani-infected mice via dampening ROS activity 2018 ·Biochemical and Biophysical Research Communications ·(unknown),Zhiliang Wu,Katsuya Sato,Hitoshi Nagaoka,Yoichi Maekawa	3
5	Mitotic catastrophe and cell death induced by depletion of centrosomal proteins 2013 ·Cell Death and Disease ·Makoto Kimura,Takashi Yoshioka,Masanao Saio,Yoshiko Banno,Hitoshi Nagaoka,Yukio Okano	69
6	Imatinib mesylate directly impairs class switch recombination through down-regulation of AID: its potential efficacy as an AID suppressor 2012 ·Blood ·Toyotaka Kawamata,Jun Lü,Tadayuki Sato,Masafumi Tanaka,Hitoshi Nagaoka,Yasutoshi Agata,(unknown),Kazuaki Yokoyama,Naoki Oyaizu,Naoya Nakamura,Kiyoshi Ando,Arinobu Tojo,Ai Kotani	5
7	Identification of a Rho family specific guanine nucleotide exchange factor, FLJ00018, as a novel actin-binding protein 2012 ·Cellular Signalling ·Katsuya Sato,(unknown),Masashi Kimura,Yukio Okano,Hitoshi Nagaoka,Takahiro Nagase,Tsuyoshi Sugiyama,Yukio Kitade,Hiroshi Ueda	9
8	Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity 2010 ·International Immunology ·Hitoshi Nagaoka,Thu Ha Tran,Maki Kobayashi,(unknown),Tasuku Honjo	31
9	Discovery of Activation‐Induced Cytidine Deaminase, the Engraver of Antibody Memory 2007 ·Advances in immunology ·Masamichi Muramatsu,Hitoshi Nagaoka,Reiko Shinkura,Nasim A. Begum,Tasuku Honjo	92
10	Negative regulation of activation-induced cytidine deaminase in B cells 2006 ·Proceedings of the National Academy of Sciences ·Taro Muto,Il‐mi Okazaki,Shuichi Yamada,Yoshimasa Tanaka,Kazuo Kinoshita,Masamichi Muramatsu,Hitoshi Nagaoka,Tasuku Honjo	76
11	Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch 2004 ·Science ·Nasim A. Begum,Kazuo Kinoshita,Naoki Kakazu,Masamichi Muramatsu,Hitoshi Nagaoka,Reiko Shinkura,Detlev Biniszkiewicz,Laurie A. Boyer,Rudolf Jaenisch,Tasuku Honjo	91
12	AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts 2002 ·Science ·Kiyotsugu Yoshikawa,Il‐mi Okazaki,(unknown),Kazuo Kinoshita,Masamichi Muramatsu,Hitoshi Nagaoka,Tasuku Honjo	312
13	Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region 2002 ·The Journal of Experimental Medicine ·Hitoshi Nagaoka,Masamichi Muramatsu,(unknown),Kazuo Kinoshita,Tasuku Honjo	162
14	Effects of Lentinus edodes mycelia on Dietary-Induced Atherosclerotic Involvement in Rabbit Aorta. 2002 ·Journal of Atherosclerosis and Thrombosis ·Tsutomu Yamada,Toshinori Oinuma,(unknown),Masako Mitsumata,(unknown),Kenji Hasegawa,Hitoshi Nagaoka,Hiroshige Itakura	36
15	RAG Expression in B Cells in Secondary Lymphoid Tissues 1999 ·Cold Spring Harbor Symposia on Quantitative Biology ·(unknown),Hitoshi Nagaoka,Ziva Misulovin,Eric Meffre,Heikyung Suh,Mila Janković,N. Yannoutsos,Rafael Casellas,Eva Besmer,F. Nina Papavasiliou,F. Xiao‐Feng Qin,Michel C. Nussenzweig	9
16	Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6) Stimulates Extracellular Signal–regulated Kinase (ERK) Activity in CD40 Signaling Along a Ras-independent Pathway 1998 ·The Journal of Experimental Medicine ·Masaki Kashiwada,Yumiko Shirakata,Jun‐ichiro Inoue,Hiroyasu Nakano,Kenji Okazaki,Ko Okumura,Tadashi Yamamoto,Hitoshi Nagaoka,Toshitada Takemori	117
17	Accumulation of somatic hypermutation and antigen‐driven selection in rapidly cycling surface Ig⁺ germinal center (GC) B cells which occupy GC at a high frequency during the primary antihapten response in mice 1997 ·European Journal of Immunology ·Hiroshi Kimoto,Hitoshi Nagaoka,(unknown),Toshiaki Mizuochi,Takachika Azuma,(unknown),Tetsutaro Sata,(unknown),Yasuko Tsunetsugu‐Yokota,Masaru Taniguchi,Toshitada Takemori	31
18	Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locusbreakdown → 1993 ·Nature Genetics ·Fumihiko Matsuda,Euy Kyun Shin,Hitoshi Nagaoka,Ryusuke Matsumura,Makoto Haino,Yosho Fukita,Shigeo Takaishi,Takashi Imai,John Riley,Rakesh Anand,Eiichi Soeda,Tasuku Honjo	276
19	Effects of YM264, a novel PAF antagonist, on puromycin aminonucleoside-induced nephropathy in the rat 1991 ·Biochemical and Biophysical Research Communications ·Toshimitsu Yamada,K. Tomioka,(unknown),Yasuhiro Sakurai,Hitoshi Nagaoka,Toshiyasu Mase	7
20	Physical map of the 3′ region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotype. 1991 ·The EMBO Journal ·(unknown),Fumihiko Matsuda,Hitoshi Nagaoka,Yosho Fukita,Takashi Imai,(unknown),E Soeda,Tasuku Honjo	102

About Hitoshi Nagaoka

Hitoshi Nagaoka is a scholar working on Immunology, Immunology and Allergy and Molecular Biology, having authored 70 papers that have together received 4.4k indexed citations. Recurring topics across this work include T-cell and B-cell Immunology (27 papers), Immune Cell Function and Interaction (18 papers) and Cytomegalovirus and herpesvirus research (9 papers). The work is most often cited by research in Immunology (2.9k citations), Genetics (385 citations) and Molecular Biology (1.8k citations). Hitoshi Nagaoka has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Tasuku Honjo, Masamichi Muramatsu, Kazuo Kinoshita, Reiko Shinkura, Nasim A. Begum, Sidonia Fagarasan, Keiichiro Suzuki, Michel C. Nussenzweig, Satomi Ito and Il‐mi Okazaki. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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