Herbert L. Heyneker

14.0k total citations · 8 hit papers
35 papers, 11.9k citations indexed

About

Herbert L. Heyneker is a scholar working on Molecular Biology, Genetics and Biotechnology. According to data from OpenAlex, Herbert L. Heyneker has authored 35 papers receiving a total of 11.9k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 13 papers in Genetics and 7 papers in Biotechnology. Recurrent topics in Herbert L. Heyneker's work include Bacterial Genetics and Biotechnology (8 papers), Bacteriophages and microbial interactions (5 papers) and DNA and Nucleic Acid Chemistry (4 papers). Herbert L. Heyneker is often cited by papers focused on Bacterial Genetics and Biotechnology (8 papers), Bacteriophages and microbial interactions (5 papers) and DNA and Nucleic Acid Chemistry (4 papers). Herbert L. Heyneker collaborates with scholars based in United States, Germany and Netherlands. Herbert L. Heyneker's co-authors include Stanley Falkow, Jorge H. Crosa, Francisco Bolívar, Herbert W. Boyer, Mary C. Betlach, Raymond L. Rodriguez, Patricia J. Greene, Raymond L. Rodriguez, David V. Goeddel and Roberto Crea and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Herbert L. Heyneker

32 papers receiving 10.1k citations

Hit Papers

Construction and characterization of new cloning vehicle.... 1977 2026 1993 2009 1977 1977 1983 1977 1995 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Construction and characterization of new cloning vehicle. II. A multipurpose cloning system
    1977 3.6k citations Francisco Bolívar, Raymond L. Rodriguez et al. Gene profile →
  2. Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.
    1977 2.6k citations Raymond L. Rodriguez, Herbert L. Heyneker et al. profile →
  3. Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli
    1983 1.0k citations William E. Holmes, Gordon A. Vehar et al. Nature profile →
  4. Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatin
    1977 610 citations Keiichi Itakura, Roberto Crea et al. profile →
  5. Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides
    1995 558 citations Willem P.C. Stemmer, Andreas Crameri et al. Gene profile →
  6. Expression in Escherichia coli of chemically synthesized genes for human insulin.
    1979 548 citations David V. Goeddel, Dennis G. Kleid et al. Proceedings of the National Academy of Sciences profile →
  7. Human leukocyte interferon produced by E. coli is biologically active
    1980 413 citations David V. Goeddel, Herbert L. Heyneker et al. Nature profile →
  8. Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone
    1979 389 citations David V. Goeddel, Herbert L. Heyneker et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Herbert L. Heyneker United States 27 8.1k 4.7k 2.1k 1.1k 910 35 11.9k
Martin Rosenberg United States 63 11.0k 1.4× 5.0k 1.1× 2.3k 1.1× 759 0.7× 609 0.7× 181 15.2k
Allan M. Maxam United States 20 18.3k 2.3× 6.2k 1.3× 3.0k 1.4× 2.9k 2.7× 574 0.6× 25 24.1k
Waclaw Szybalski United States 56 8.7k 1.1× 3.9k 0.8× 3.5k 1.7× 875 0.8× 298 0.3× 252 11.5k
I Lehman United States 73 13.0k 1.6× 4.9k 1.0× 2.2k 1.0× 1.1k 1.0× 394 0.4× 190 16.4k
C C Richardson United States 56 10.9k 1.3× 5.6k 1.2× 3.5k 1.6× 970 0.9× 292 0.3× 116 13.9k
Sankar Adhya United States 67 10.9k 1.3× 6.8k 1.4× 5.3k 2.5× 1.2k 1.1× 965 1.1× 204 15.4k
Alan H. Rosenberg United States 18 7.3k 0.9× 2.8k 0.6× 1.7k 0.8× 816 0.8× 473 0.5× 19 9.5k
Aaron J. Shatkin United States 68 11.0k 1.4× 3.1k 0.7× 2.0k 0.9× 1.4k 1.3× 226 0.2× 197 15.4k
Jeffrey K. Pullen United States 11 6.9k 0.8× 1.9k 0.4× 696 0.3× 1.0k 1.0× 567 0.6× 14 10.4k
Dominique Belin Switzerland 52 8.0k 1.0× 4.3k 0.9× 1.5k 0.7× 356 0.3× 579 0.6× 114 15.0k

Countries citing papers authored by Herbert L. Heyneker

Since Specialization
Citations

This map shows the geographic impact of Herbert L. Heyneker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Herbert L. Heyneker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Herbert L. Heyneker more than expected).

Fields of papers citing papers by Herbert L. Heyneker

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Herbert L. Heyneker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Herbert L. Heyneker. The network helps show where Herbert L. Heyneker may publish in the future.

Co-authorship network of co-authors of Herbert L. Heyneker

This figure shows the co-authorship network connecting the top 25 collaborators of Herbert L. Heyneker. A scholar is included among the top collaborators of Herbert L. Heyneker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Herbert L. Heyneker. Herbert L. Heyneker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Stemmer, Willem P.C., et al.. (1995). Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides. Gene. 164(1). 49–53. 558 indexed citations breakdown →
2.
Chang, Chung Nan, Michael L. Key, Barry R. Bochner, Herbert L. Heyneker, & Gregory C. Gray. (1987). High-level secretion of human growth hormone by Escherichia coli. Gene. 55(2-3). 189–196. 137 indexed citations
3.
Vehar, Gordon A., et al.. (1987). ROLE OF PROTEOLYSIS AT ARGININE-275 OF TISSUE PLASMINOGEN ACTIVATOR (t-PA) AS ASSESSED BY SITE-DIRECTED MUTAGENESIS. Thrombosis and Haemostasis. 4 indexed citations
4.
Tate, Keri, Deborah L. Higgins, William E. Holmes, et al.. (1987). Functional role of proteolytic cleavage at arginine-275 of human tissue plasminogen activator as assessed by site-directed mutagenesis. Biochemistry. 26(2). 338–343. 118 indexed citations
5.
Perry, L. Jeanne, Herbert L. Heyneker, & Ronald Wetzel. (1985). Non-toxic expression in Escherichia coli of a plasmid-encoded gene for phage T4 lysozyme. Gene. 38(1-3). 259–264. 26 indexed citations
6.
7.
Valle, Fernando, et al.. (1984). Complete nucleotide sequence of the glutamate dehydrogenase gene from Escherichia coli K-12. Gene. 27(2). 193–199. 43 indexed citations
8.
Seeburg, Peter H., John P. Adelman, Herman A. de Boer, et al.. (1983). Efficient Bacterial Expression of Bovine and Porcine Growth Hormones. DNA. 2(1). 37–45. 120 indexed citations
9.
Picken, Roger N., A J Mazaitis, Werner K. Maas, Michael W. Rey, & Herbert L. Heyneker. (1983). Nucleotide sequence of the gene for heat-stable enterotoxin II of Escherichia coli. Infection and Immunity. 42(1). 269–275. 125 indexed citations
10.
Wetzel, Ronald, Herbert L. Heyneker, David V. Goeddel, et al.. (1981). Corrections - Production of Biologically Active Nα-Desacetylthymosin α1 in Escherichia coli through Expression of a Chemically Synthesized Gene. Biochemistry. 20(17). 5094–5094. 1 indexed citations
11.
Wetzel, Ronald, Dennis G. Kleid, Roberto Crea, et al.. (1981). Expression in escherichia coli of a chemically synthesized gene for a “mini-c” analog of human proinsulin. Gene. 16(1-3). 63–71. 38 indexed citations
12.
Riggs, Arthur D., Keiichi Itakura, Roberto Crea, et al.. (1980). Synthesis, Cloning, and Expression of Hormone Genes in Escherichia coli. Elsevier eBooks. 36. 261–276. 1 indexed citations
13.
Stuitje, Antoine R., E. Veltkamp, J. Maat, & Herbert L. Heyneker. (1980). The nucleotide sequence surrounding the replication origin of the cop3 mutant of the bacterio-cinogenic plasmid Clo DF13. Nucleic Acids Research. 8(7). 1459–1473. 23 indexed citations
14.
Goeddel, David V., Herbert L. Heyneker, René Arentzen, et al.. (1979). Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone. Nature. 281(5732). 544–548. 389 indexed citations breakdown →
15.
Rodriguez, Raymond L., Robert W. West, Herbert L. Heyneker, Francisco Bolívar, & H W Boyer. (1979). Characterizing wild-type and mutant promoters of the tetracycline resistance gene in pBR313. Nucleic Acids Research. 6(10). 3267–3288. 64 indexed citations
16.
Greene, Patricia J., Herbert L. Heyneker, Francisco Bolívar, et al.. (1978). A general method for the purification of restriction enzymes. Nucleic Acids Research. 5(7). 2373–2380. 296 indexed citations
17.
Bolívar, Francisco, Mary C. Betlach, Herbert L. Heyneker, et al.. (1977). Origin of replication of pBR345 plasmid DNA.. Proceedings of the National Academy of Sciences. 74(12). 5265–5269. 98 indexed citations
18.
Sugino, Akio, H. M. Goodman, Herbert L. Heyneker, et al.. (1977). Interaction of bacteriophage T4 RNA and DNA ligases in joining of duplex DNA at base-paired ends.. Journal of Biological Chemistry. 252(11). 3987–3994. 100 indexed citations
19.
Heyneker, Herbert L., John Shine, Howard M. Goodman, et al.. (1976). Synthetic lacoperator DNA is functional in vivo. Nature. 263(5580). 748–752. 151 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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