Herbert L. Heyneker

14.0k citations

35 papers · 11.9k indexed · 8 hit papers · h-index 27

Molecular Biology top 0.5%
Genetics top 0.1%
Ecology top 0.5%
Plant Science top 2%
Biotechnology top 0.2%

Co-authors: Jorge H. Crosa Stanley Falkow Francisco Bolívar Herbert W. Boyer Mary C. Betlach Raymond L. Rodriguez Patricia J. Greene David V. Goeddel
Topics: Bacterial Genetics and Biotechnology (8 papers)Bacteriophages and microbial interactions (5 papers)Peptidase Inhibition and Analysis (4 papers)
Cited by: Genetics Endocrinology Molecular Medicine
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: United States Germany Netherlands

In The Last Decade

Herbert L. Heyneker

32 papers receiving 10.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 3.6k citations Francisco Bolívar, Raymond L. Rodriguez et al. Gene profile →
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.

1977 2.6k citations Raymond L. Rodriguez, Herbert L. Heyneker et al. profile →
Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

1983 1.0k citations Diane Pennica, William E. Holmes et al. Nature profile →
Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatin

1977 610 citations Keiichi Itakura, Roberto Crea et al. Science profile →
Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

1995 558 citations Willem P.C. Stemmer, Andreas Crameri et al. Gene profile →
Expression in Escherichia coli of chemically synthesized genes for human insulin.

1979 548 citations David V. Goeddel, Dennis G. Kleid et al. Proceedings of the National Academy of Sciences profile →
Human leukocyte interferon produced by E. coli is biologically active

1980 413 citations David V. Goeddel, Elizabeth Yelverton et al. Nature profile →
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone

1979 389 citations David V. Goeddel, Herbert L. Heyneker et al. Nature profile →

Peers

Countries citing papers authored by Herbert L. Heyneker

Since Specialization

Citations

This map shows the geographic impact of Herbert L. Heyneker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Herbert L. Heyneker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Herbert L. Heyneker more than expected).

Fields of papers citing papers by Herbert L. Heyneker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Herbert L. Heyneker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Herbert L. Heyneker. The network helps show where Herbert L. Heyneker may publish in the future.

Co-authorship network of co-authors of Herbert L. Heyneker

This figure shows the co-authorship network connecting the top 25 collaborators of Herbert L. Heyneker. A scholar is included among the top collaborators of Herbert L. Heyneker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Herbert L. Heyneker. Herbert L. Heyneker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotidesbreakdown → 1995 ·Gene ·Willem P.C. Stemmer,Andreas Crameri,(unknown),Thomas M. Brennan,Herbert L. Heyneker	558
2	High-level secretion of human growth hormone by Escherichia coli 1987 ·Gene ·Chung Nan Chang,Michael L. Key,Barry R. Bochner,Herbert L. Heyneker,Gregory C. Gray	137
3	ROLE OF PROTEOLYSIS AT ARGININE-275 OF TISSUE PLASMINOGEN ACTIVATOR (t-PA) AS ASSESSED BY SITE-DIRECTED MUTAGENESIS 1987 ·Thrombosis and Haemostasis ·Gordon A. Vehar,K. Tate,Deborah L. Higgins,(unknown),Herbert L. Heyneker	4
4	Non-toxic expression in Escherichia coli of a plasmid-encoded gene for phage T4 lysozyme 1985 ·Gene ·L. Jeanne Perry,Herbert L. Heyneker,Ronald Wetzel	26
5	Periplasmic production of correctly processed human growth hormone in Escherichia coli: natural and bacterial signal sequences are interchangeable 1985 ·Gene ·Gregory L. Gray,(unknown),(unknown),Herbert L. Heyneker,Chung Nan Chang	94
6	Cloning and Expression of the Gene for Pro-urokinase in Escherichia coli 1985 ·Bio/Technology ·William E. Holmes,Diane Pennica,(unknown),Michael W. Rey,(unknown),Gerd Steffens,Herbert L. Heyneker	185
7	Complete nucleotide sequence of the glutamate dehydrogenase gene from Escherichia coli K-12 1984 ·Gene ·Fernando Valle,Baltazar Becerril,(unknown),Peter H. Seeburg,Herbert L. Heyneker,Francisco Bolívar	43
8	Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. 1984 ·Proceedings of the National Academy of Sciences ·Gregory L. Gray,Douglas H. Smith,(unknown),Richard N. Harkins,Michael L. Vasil,(unknown),Herbert L. Heyneker	235
9	Efficient Bacterial Expression of Bovine and Porcine Growth Hormones 1983 ·DNA ·Peter H. Seeburg,(unknown),John P. Adelman,Herman A. de Boer,Joel S. Hayflick,Parkash Jhurani,David V. Goeddel,Herbert L. Heyneker	120
10	Nucleotide sequence of the gene for heat-stable enterotoxin II of Escherichia coli 1983 ·Infection and Immunity ·Roger N. Picken,A J Mazaitis,Werner K. Maas,Michael W. Rey,Herbert L. Heyneker	125
11	Corrections - Production of Biologically Active N^α-Desacetylthymosin α₁ in Escherichia coli through Expression of a Chemically Synthesized Gene 1981 ·Biochemistry ·Ronald Wetzel,Herbert L. Heyneker,David V. Goeddel,Parkash Jhurani,(unknown),(unknown),Teresa L. K. Low,John E. McClure,Gary B. Thurman,Allan L. Goldstein	1
12	Synthesis, Cloning, and Expression of Hormone Genes in Escherichia coli 1980 ·Elsevier eBooks ·Arthur D. Riggs,Keiichi Itakura,Roberto Crea,(unknown),Adam Kraszewski,David V. Goeddel,Dennis G. Kleid,Daniel G. Yansura,Francisco Bolívar,Herbert L. Heyneker	1
13	Human leukocyte interferon produced by E. coli is biologically activebreakdown → 1980 ·Nature ·David V. Goeddel,Elizabeth Yelverton,Axel Ullrich,Herbert L. Heyneker,Giuseppe Miozzari,William E. Holmes,Peter H. Seeburg,Thomas J. Dull,Laurie May,N. Stebbing,Roberto Crea,Shuichiro Maeda,Russell McCandliss,Alan Sloma,John Tabor,Mitchell Gross,P C Familletti,Sidney Pestka	413
14	Construction of new cloning vehicles with genes of the tryptophan operon of Escherichia coli as genetic markers 1980 ·Gene ·B.E. Enger-Valk,Herbert L. Heyneker,R.A. Oosterbaan,Peter H. Pouwels	23
15	Direct expression in Escherichia coli of a DNA sequence coding for human growth hormonebreakdown → 1979 ·Nature ·David V. Goeddel,Herbert L. Heyneker,(unknown),René Arentzen,Keiichi Itakura,Daniel G. Yansura,Michael J. Ross,Giuseppe Miozzari,Roberto Crea,Peter H. Seeburg	389
16	Characterizing wild-type and mutant promoters of the tetracycline resistance gene in pBR313 1979 ·Nucleic Acids Research ·Raymond L. Rodriguez,Robert W. West,Herbert L. Heyneker,Francisco Bolívar,H W Boyer	64
17	Origin of replication of pBR345 plasmid DNA. 1977 ·Proceedings of the National Academy of Sciences ·Francisco Bolívar,Mary C. Betlach,Herbert L. Heyneker,John Shine,Raymond L. Rodriguez,H W Boyer	98
18	Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatinbreakdown → 1977 ·Science ·Keiichi Itakura,(unknown),Roberto Crea,Arthur D. Riggs,Herbert L. Heyneker,Francisco Bolívar,Herbert W. Boyer	610
19	Synthetic lacoperator DNA is functional in vivo 1976 ·Nature ·Herbert L. Heyneker,John Shine,Howard M. Goodman,Herbert W. Boyer,John M. Rosenberg,Richard E. Dickerson,Saran A. Narang,Keiichi Itakura,Syr-Yaung Lin,Arthur D. Riggs	151
20	Involvement of Escherichia coli DNA Polymerase-I-Associated 5′→3′ Exonuclease in Excision-Repair of UV-Damaged DNA 1975 ·Herbert L. Heyneker,Hans Klenow	4

About Herbert L. Heyneker

Herbert L. Heyneker is a scholar working on Biotechnology, Genetics and Endocrinology, having authored 35 papers that have together received 11.9k indexed citations. Recurring topics across this work include Bacterial Genetics and Biotechnology (8 papers), Bacteriophages and microbial interactions (5 papers) and Peptidase Inhibition and Analysis (4 papers). The work is most often cited by research in Genetics (4.7k citations), Endocrinology (700 citations) and Molecular Medicine (627 citations). Herbert L. Heyneker has collaborated with scholars based in United States, Germany and Netherlands. Frequent co-authors include Jorge H. Crosa, Stanley Falkow, Francisco Bolívar, Herbert W. Boyer, Mary C. Betlach, Raymond L. Rodriguez, Patricia J. Greene, Raymond L. Rodriguez, David V. Goeddel and Roberto Crea. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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