Heping Shi

4.6k total citations · 4 hit papers
15 papers, 3.6k citations indexed

About

Heping Shi is a scholar working on Molecular Biology, Immunology and Infectious Diseases. According to data from OpenAlex, Heping Shi has authored 15 papers receiving a total of 3.6k indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Molecular Biology, 6 papers in Immunology and 3 papers in Infectious Diseases. Recurrent topics in Heping Shi's work include interferon and immune responses (6 papers), Viral Infections and Vectors (3 papers) and Immune Response and Inflammation (3 papers). Heping Shi is often cited by papers focused on interferon and immune responses (6 papers), Viral Infections and Vectors (3 papers) and Immune Response and Inflammation (3 papers). Heping Shi collaborates with scholars based in United States, Italy and France. Heping Shi's co-authors include Chuo Chen, Zhijian J. Chen, Lijun Sun, Jiaxi Wu, Xiang Chen, Fenghe Du, Xuewu Zhang, Xu Zhang, Shuiqing Hu and Hua Wang and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Heping Shi

15 papers receiving 3.6k citations

Hit Papers

Cyclic GMP-AMP Is an Endogenous Second Messenger in Innat... 2012 2026 2016 2021 2012 2013 2017 2022 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
    2012 1.9k citations Jiaxi Wu, Lijun Sun et al. Science profile →
  2. Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
    2013 822 citations Xu Zhang, Heping Shi et al. Molecular Cell profile →
  3. cGAS is essential for the antitumor effect of immune checkpoint blockade
    2017 425 citations Hua Wang, Shuiqing Hu et al. Proceedings of the National Academy of Sciences profile →
  4. Tumor-targeted delivery of a STING agonist improves cancer immunotherapy
    2022 145 citations Youtong Wu, Yan Fang et al. Proceedings of the National Academy of Sciences profile →

Peers

Heping Shi
Thomas Zillinger Germany
Marion Goldeck Germany
Andrea Kröger Germany
Carina C. de Oliveira Mann Germany
Tobias Deimling Germany
Tuo Li United States
Delphine Goubau United Kingdom
Sun Hur United States
Edward E. Lemmens United States
Beihua Dong United States
Thomas Zillinger Germany
Heping Shi
Citations per year, relative to Heping Shi Heping Shi (= 1×) peers Thomas Zillinger

Countries citing papers authored by Heping Shi

Since Specialization
Citations

This map shows the geographic impact of Heping Shi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Heping Shi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Heping Shi more than expected).

Fields of papers citing papers by Heping Shi

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Heping Shi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Heping Shi. The network helps show where Heping Shi may publish in the future.

Co-authorship network of co-authors of Heping Shi

This figure shows the co-authorship network connecting the top 25 collaborators of Heping Shi. A scholar is included among the top collaborators of Heping Shi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Heping Shi. Heping Shi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

15 of 15 papers shown
1.
Zhang, Chenyue, Yue Shen, Ming-Yang Huang, et al.. (2025). Dynamic hydrogel mechanics in organoid engineering: From matrix design to translational paradigms. Bioactive Materials. 55. 144–170. 2 indexed citations
2.
Lu, Yong, Lin You, Jessica A. Kilgore, et al.. (2023). Orthogonal Hydroxyl Functionalization of cGAMP Confers Metabolic Stability and Enables Antibody Conjugation. ACS Central Science. 9(12). 2298–2305. 3 indexed citations
3.
Wu, Youtong, Yan Fang, Heping Shi, et al.. (2022). Tumor-targeted delivery of a STING agonist improves cancer immunotherapy. Proceedings of the National Academy of Sciences. 119(49). e2214278119–e2214278119. 145 indexed citations breakdown →
4.
Zhang, Li-Shu, Xunlei Kang, Jianming Lü, et al.. (2018). Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9. EBioMedicine. 39. 145–158. 19 indexed citations
5.
Shi, Heping, et al.. (2018). A synthetic combinatorial approach to disabling deviant Hedgehog signaling. Scientific Reports. 8(1). 1133–1133. 6 indexed citations
6.
Wang, Hua, Shuiqing Hu, Xiang Chen, et al.. (2017). cGAS is essential for the antitumor effect of immune checkpoint blockade. Proceedings of the National Academy of Sciences. 114(7). 1637–1642. 425 indexed citations breakdown →
7.
Lomenick, Brett, Heping Shi, Jing Huang, & Chuo Chen. (2015). Identification and characterization of β-sitosterol target proteins. Bioorganic & Medicinal Chemistry Letters. 25(21). 4976–4979. 23 indexed citations
8.
Zhang, Wei, et al.. (2015). SLPI knockdown induced pancreatic ductal adenocarcinoma cells proliferation and invasion. Cancer Cell International. 15(1). 37–37. 10 indexed citations
9.
Shi, Heping, Jiaxi Wu, Zhijian J. Chen, & Chuo Chen. (2015). Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING. Proceedings of the National Academy of Sciences. 112(29). 8947–8952. 69 indexed citations
10.
Fan, Chih-Wei, Baozhi Chen, Irene Franco, et al.. (2014). The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation. Chemistry & Biology. 21(12). 1680–1689. 20 indexed citations
11.
Shi, Heping, et al.. (2014). Construction of the 5,6,7-tricyclic skeleton of lancifodilactone F. Tetrahedron Letters. 56(23). 3225–3227. 15 indexed citations
12.
Zhang, Xu, Heping Shi, Jiaxi Wu, et al.. (2013). Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING. Molecular Cell. 51(2). 226–235. 822 indexed citations breakdown →
13.
Wang, Xiaolei, Jesung Moon, Michael Dodge, et al.. (2013). The Development of Highly Potent Inhibitors for Porcupine. Journal of Medicinal Chemistry. 56(6). 2700–2704. 90 indexed citations
14.
Wu, Jiaxi, Lijun Sun, Xiang Chen, et al.. (2012). Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA. Science. 339(6121). 826–830. 1901 indexed citations breakdown →
15.
Dodge, Michael, Jesung Moon, Rubina Tuladhar, et al.. (2012). Diverse Chemical Scaffolds Support Direct Inhibition of the Membrane-bound O-Acyltransferase Porcupine. Journal of Biological Chemistry. 287(27). 23246–23254. 65 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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