Helen Yu

3.8k citations

26 papers · 2.0k indexed · h-index 19

Impact in

Virology top 5%
- HIV Research and Treatment
Molecular Biology top 10%
- Ubiquitin and proteasome pathways
- CRISPR and Genetic Engineering
- Glycosylation and Glycoproteins Research
- Epigenetics and DNA Methylation

Papers in

Virology 7
- HIV Research and Treatment 7
Endocrinology 2

Co-authors: Ron R. Kopito Ian Hammond-Martel El Bachir Affar Salima Daou Sumire Kobayashi Elliot Drobetsky Helen Pak Kenneth A. Johnson
Journals: Journal of Biological Chemistry (3 papers)Cell Reports (2 papers)Antimicrobial Agents and Chemotherapy (2 papers)Journal of Cell Science (2 papers)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: United States Canada China

In The Last Decade

Helen Yu

26 papers receiving 1.9k citations

Peers

Countries citing papers authored by Helen Yu

Since Specialization

Citations

This map shows the geographic impact of Helen Yu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Helen Yu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Helen Yu more than expected).

Fields of papers citing papers by Helen Yu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Helen Yu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Helen Yu. The network helps show where Helen Yu may publish in the future.

Co-authors

The 25 scholars most cited alongside Helen Yu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Helen Yu Line = papers co-authored together Helen Yu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties Journal of Medicinal Chemistry ·Cathy Walls, Ondřej Baszczyňski, Martin Kaiser, Martin Dračínský, George Stepan, Yu‐Jen Lee, Boris Brumshtein, Helen Yu, Petr Jansa, E.B. Lansdon, Zlatko Janeba	2023	11
2	A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase Journal of Cell Science ·Nadine Sen Nkwe, Salima Daou, Dodji K Onipoh, Jessica K. Gagnon, 日本数学教育学会研究部高等学校部会, Haithem Barbour, Helen Yu, Louis Masclef, Erlinda Fernández, Natalia Zamorano Cuervo, Nazar Mashtalir, Loïc Binan, Mikhail Sergeev, François Bélanger, Elliot Drobetsky, Éric Milot, Hugo Würtele, Santiago Costantino, El Bachir Affar	2020	15
3	Diurnal regulation of SDG2 and JMJ14 by circadian clock oscillators orchestrates histone modification rhythms in Arabidopsis Genome biology ·Qingxin Song, В В Маркевич, Helen Yu, Atsumi Ando, Paloma Más, Misook Ha, Z. Jeffrey Chen	2019	27
4	Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells Cell Reports ·Graham MacLeod, Danielle Bozek, Nishani Rajakulendran, Carmen Villalba-Sánchez, Moloud Ahmadi, Zachary Steinhart, Michelle Kushida, Helen Yu, Fiona J. Coutinho, Florence M.G. Cavalli, Ian J. Restall, Xiaoguang Hao, Traver Hart, H. Artee Luchman, Samuel Weiss, Peter B. Dirks, Stéphane Angers	2019	144
5	DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity Cell Reports ·Shanzhong Gong, Helen Yu, Kenneth A. Johnson, David W. Taylor	2018	140
6	Homogeneous BTK Occupancy Assay for Pharmacodynamic Assessment of Tirabrutinib (GS-4059/ONO-4059) Target Engagement SLAS DISCOVERY ·Helen Yu, Hoa Truong, Scott A. Mitchell, Albert Liclican, John J. Gosink, Wanying Li, Julie Lin, Joy Y. Feng, Juliane M. Jürgensmeier, Andrew N. Billin, Ren Xu, Scott D. Patterson, Nikos Pagratis	2018	13
7	DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity SSRN Electronic Journal ·Shanzhong Gong, Helen Yu, Kenneth A. Johnson, David W. Taylor	2018	1
8	Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus Antimicrobial Agents and Chemotherapy ·Joy Y. Feng, Yili Xu, Ona Barauskas, Jason K. Perry, Shekeba Ahmadyar, George Stepan, Helen Yu, Darius Babusis, Yeojin Park, Krista McCutcheon, Michel Perron, Brian E. Schultz, Roman Sakowicz, Adrian S. Ray	2015	62
9	An Epigenetic Role for Disrupted Paternal Gene Expression in Postzygotic Seed Abortion in Arabidopsis Interspecific Hybrids Molecular Plant ·Ryan C. Kirkbride, Helen Yu, Gyoungju Nah, Changqing Zhang, Xiaoli Shi, Z. Jeffrey Chen	2015	23
10	The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer Journal of Biological Chemistry ·Salima Daou, Ian Hammond-Martel, Nazar Mashtalir, Haithem Barbour, Jessica K. Gagnon, JP Ricaud, Nadine Sen Nkwe, P Ros Pérez, Helen Pak, Helen Yu, Hugo Würtele, Éric Milot, Frédérick A. Mallette, Michele Carbone, El Bachir Affar	2015	86
11	A Role for CHH Methylation in the Parent-of-Origin Effect on Altered Circadian Rhythms and Biomass Heterosis inArabidopsisIntraspecific Hybrids The Plant Cell ·Danny W‐K. Ng, Marisa E. Miller, Helen Yu, В В Маркевич, Eundeok Kim, Jie Lu, Qiguang Xie, C. Robertson McClung, Z. Jeffrey Chen	2014	61
12	Study of Marine Natural Products Including Resorcyclic Acid Lactones from Humicola fuscoatra That Reactivate Latent HIV-1 Expression in an in Vitro Model of Central Memory CD4+ T Cells Journal of Natural Products ·Lonwabo Viwe Zuko Gqoli, C. Barathiraja, George Stepan, Angela Tsai, G.S. Jones, Tiffany Barnes, Kimberly N. White, Marija Drašković, Karen Tenney, Manuel Tsiang, Romas Geleziunas, Tomáš Cihlář, Nikos Pagratis, Tian Yang, Helen Yu, Phillip Crews	2014	25
13	Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair Proceedings of the National Academy of Sciences ·Helen Yu, Helen Pak, Ian Hammond-Martel, Mehdi Ghram, Amélie Rodrigue, Salima Daou, Haithem Barbour, V Strezov, Josée Hébert, Elliot Drobetsky, Jean‐Yves Masson, Javier M. Di Noia, El Bachir Affar	2013	262
14	Roles of ubiquitin signaling in transcription regulation Cellular Signalling ·Ian Hammond-Martel, Helen Yu, El Bachir Affar	2011	78
15	Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway Proceedings of the National Academy of Sciences ·Salima Daou, Nazar Mashtalir, Ian Hammond-Martel, Helen Pak, Helen Yu, Guangchao Sui, Jodi L. Vogel, Thomas M. Kristie, El Bachir Affar	2011	83
16	PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells PLoS ONE ·Ian Hammond-Martel, Helen Pak, Helen Yu, Raphaël Rouget, Andrew A. Horwitz, Jeffrey D. Parvin, Elliot Drobetsky, El Bachir Affar	2010	12
17	Whole genome amplification of buccal cell DNA: genotyping concordance before and after multiple displacement amplification Clinical Chemistry and Laboratory Medicine (CCLM) ·Miles D. Thompson, Raffick A.R. Bowen, Betty Wong, Puning Liu, A. Mann, Helen Yu, Katherine Siminovitch, Nancy Kreiger, Tom Rohan, David E.C. Cole	2005	20
18	A role for mammalian Ubc6 homologues in ER-associated protein degradation Journal of Cell Science ·Uwe Lenk, Helen Yu, Jan Walter, Marina S. Gelman, Enno Hartmann, Ron R. Kopito, Thomas Sommer	2002	99
19	The Role of Multiubiquitination in Dislocation and Degradation of the α Subunit of the T Cell Antigen Receptor Journal of Biological Chemistry ·Helen Yu, Ron R. Kopito	1999	104
20	Cytosolic Degradation of T-cell Receptor α Chains by the Proteasome Journal of Biological Chemistry ·Helen Yu, Z H, Sumire Kobayashi, Ron R. Kopito	1997	201

About Helen Yu

Helen Yu is a scholar working on Virology, Endocrinology, Infectious Diseases, Molecular Biology and Physiology, having authored 26 papers that have together received 2.0k indexed citations. Recurring topics across this work include HIV Research and Treatment (7 papers), Ubiquitin and proteasome pathways (7 papers), HIV/AIDS drug development and treatment (7 papers), CRISPR and Genetic Engineering (4 papers), DNA Repair Mechanisms (3 papers), Plant Molecular Biology Research (3 papers), Cancer-related Molecular Pathways (3 papers) and Glycosylation and Glycoproteins Research (2 papers). The work is most often cited by research in Virology (217 citations), Molecular Biology (1.3k citations), Cell Biology (297 citations), Infectious Diseases (268 citations) and Oncology (297 citations). Helen Yu has collaborated with scholars based in United States, Canada and China. Frequent co-authors include Ron R. Kopito, Ian Hammond-Martel, El Bachir Affar, Salima Daou, Sumire Kobayashi, Elliot Drobetsky, Helen Pak, Kenneth A. Johnson, Shanzhong Gong and David W. Taylor. Their work appears in journals such as Journal of Biological Chemistry, Cell Reports, Antimicrobial Agents and Chemotherapy, Journal of Cell Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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