Helen Tuppen

2.9k citations

34 papers · 1.7k indexed · h-index 20

Molecular Biology top 5%
Clinical Biochemistry top 0.5%
Cellular and Molecular Neuroscience top 10%
Genetics
Physiology

Co-authors: Robert W. Taylor Douglass M. Turnbull Emma L. Blakely Robert N. Lightowlers Patrick F. Chinnery Julie L. Murphy Gareth D. Greggains Lyndsey Craven
Topics: Mitochondrial Function and Pathology (31 papers)Metabolism and Genetic Disorders (21 papers)ATP Synthase and ATPases Research (11 papers)
Cited by: Clinical Biochemistry Aging Molecular Biology
Journals: Nature Nucleic Acids Research PLoS ONE
Partner nations: United Kingdom Italy United States

In The Last Decade

Helen Tuppen

32 papers receiving 1.7k citations

Peers

Countries citing papers authored by Helen Tuppen

Since Specialization

Citations

This map shows the geographic impact of Helen Tuppen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Helen Tuppen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Helen Tuppen more than expected).

Fields of papers citing papers by Helen Tuppen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Helen Tuppen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Helen Tuppen. The network helps show where Helen Tuppen may publish in the future.

Co-authorship network of co-authors of Helen Tuppen

This figure shows the co-authorship network connecting the top 25 collaborators of Helen Tuppen. A scholar is included among the top collaborators of Helen Tuppen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Helen Tuppen. Helen Tuppen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A study protocol to investigate if acipimox improves muscle function and sarcopenia: an open-label, uncontrolled, before-and-after experimental medicine feasibility study in community-dwelling older adults 2024 ·BMJ Open ·Claire McDonald,(unknown),(unknown),(unknown),Silvia Del Din,Gráinne S. Gorman,Kieren G. Hollingsworth,(unknown),Rana Zia Ur Rehman,Lynn Rochester,(unknown),(unknown),Helen Tuppen,(unknown),Miles D. Witham	0
2	Single Cell Analysis of Mitochondrial DNA Deletions 2023 ·Methods in molecular biology ·Helen Tuppen,Amy K. Reeve,Amy E. Vincent	2
3	Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis 2016 ·Nucleic Acids Research ·Karolina A. Rygiel,Helen Tuppen,John P. Grady,Amy E. Vincent,Emma L. Blakely,Amy K. Reeve,Robert W. Taylor,Martin Picard,James Miller,Douglass M. Turnbull	33
4	Pathogenic mitochondrial mt-tRNAAla variants are uniquely associated with isolated myopathy 2015 ·European Journal of Human Genetics ·Diana Lehmann,(unknown),Pushpa Raj Joshi,Steven Hardy,Helen Tuppen,(unknown),Emma L. Blakely,Christian Bamberg,Stephan Zierz,Marcus Deschauer,Robert W. Taylor	20
5	Triplex real-time PCR–an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells 2015 ·Scientific Reports ·Karolina A. Rygiel,John P. Grady,Robert W. Taylor,Helen Tuppen,Douglass M. Turnbull	32
6	Short peptides from leucyl-tRNA synthetase rescue disease-causing mitochondrial tRNA point mutations 2015 ·Human Molecular Genetics ·Elena Perli,Annarita Fiorillo,Carla Giordano,Annalinda Pisano,Arianna Montanari,Paola Grazioli,Antonio Francesco Campese,Patrizio Di Micco,Helen Tuppen,Ilaria Genovese,Elena Poser,Carmela Preziuso,Robert W. Taylor,Veronica Morea,Gianni Colotti,Giulia d’Amati	19
7	Therapeutic potential of somatic cell nuclear transfer for degenerative disease caused by mitochondrial DNA mutations 2014 ·Scientific Reports ·Gareth D. Greggains,Lisa Lister,Helen Tuppen,Qí Zhāng,(unknown),Nilendran Prathalingam,Louise Hyslop,Lyndsey Craven,Zbigniew Polański,Alison Murdoch,Douglass M. Turnbull,Mary Herbert	14
8	A novel mitochondrial DNA m.7507A>G mutation is only pathogenic at high levels of heteroplasmy 2014 ·Neuromuscular Disorders ·(unknown),Helen Tuppen,Benno Küsters,Martin Lammens,Jan Smeıtınk,Robert W. Taylor,Richard J. Rodenburg,Saskia B. Wortmann	6
9	Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing 2014 ·PLoS Genetics ·Laura C. Greaves,Marco Nooteboom,Joanna L. Elson,Helen Tuppen,Geoffrey A. Taylor,Daniel M. Commane,Ramesh Arasaradnam,Konstantin Khrapko,Robert W. Taylor,Thomas B. L. Kirkwood,John C. Mathers,Douglass M. Turnbull	112
10	Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt‐ tRNA mutations 2014 ·EMBO Molecular Medicine ·(unknown),Arianna Montanari,Agata Rozanska,Helen Tuppen,Abdulraheem Ali Almalki,(unknown),Laura Frontali,Silvia Francisci,Robert N. Lightowlers,Zofia M. Chrzanowska‐Lightowlers	43
11	The isolated carboxy‐terminal domain of human mitochondrial leucyl‐ tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells 2014 ·EMBO Molecular Medicine ·Elena Perli,Carla Giordano,Annalinda Pisano,Arianna Montanari,Antonio Francesco Campese,Aurelio Reyes,Daniele Ghezzi,Alessia Nasca,Helen Tuppen,Maurizia Orlandi,Patrizio Di Micco,Elena Poser,Robert W. Taylor,Gianni Colotti,Silvia Francisci,Veronica Morea,Laura Frontali,Massimo Zeviani,Giulia d’Amati	37
12	Accurate Measurement of Mitochondrial DNA Deletion Level and Copy Number Differences in Human Skeletal Muscle 2014 ·PLoS ONE ·John P. Grady,Julie L. Murphy,Emma L. Blakely,Ronald G. Haller,Robert W. Taylor,Douglass M. Turnbull,Helen Tuppen	50
13	Mutations in the mitochondrial tRNASer(AGY) gene are associated with deafness, retinal degeneration, myopathy and epilepsy 2012 ·European Journal of Human Genetics ·Helen Tuppen,K Naess,Nancy G. Kennaway,Mazhor Aldosary,Nicole Lesko,John W. Yarham,Helene Bruhn,Rolf Wibom,Inger Nennesmo,Richard G. Weleber,Emma L. Blakely,Robert W. Taylor,Robert McFarland	11
14	Mitochondrial DNA disease: new options for prevention 2011 ·Human Molecular Genetics ·Lyndsey Craven,Joanna L. Elson,Laura Irving,Helen Tuppen,Lisa Lister,Gareth D. Greggains,(unknown),Alison Murdoch,Mary Herbert,Douglass M. Turnbull	46
15	Isoleucyl-tRNA synthetase levels modulate the penetrance of a homoplasmic m.4277T>C mitochondrial tRNAIle mutation causing hypertrophic cardiomyopathy 2011 ·Human Molecular Genetics ·Elena Perli,Carla Giordano,Helen Tuppen,Monica Montopoli,Arianna Montanari,Maurizia Orlandi,Annalinda Pisano,Daniela Catanzaro,Laura Caparrotta,Beatrice Musumeci,Camillo Autore,Veronica Morea,Patrizio Di Micco,Antonio Francesco Campese,Martina Leopizzi,Pietro Gallo,Silvia Francisci,Laura Frontali,Robert W. Taylor,Giulia d’Amati	55
16	Long-term survival of neonatal mitochondrial complex III deficiency associated with a novel BCS1L gene mutation 2010 ·Molecular Genetics and Metabolism ·Helen Tuppen,Janev Fehmi,Birgit Czermin,P Goffrini,Francesca Meloni,Iliana Ferrero,Langping He,Emma L. Blakely,Robert McFarland,Rita Horváth,Douglass M. Turnbull,Robert W. Taylor	24
17	Nuclear factors involved in mitochondrial translation cause a subgroup of combined respiratory chain deficiency 2010 ·Brain ·John P. Kemp,Paul Smith,Angela Pyle,(unknown),Helen Tuppen,Ulrike Schara,Beril Talim,Haluk Topaloğlu,Elke Holinski‐Feder,Angela Abicht,Birgit Czermin,Hanns Lochmüller,Robert McFarland,Patrick F. Chinnery,Zofia M. Chrzanowska‐Lightowlers,Robert N. Lightowlers,Robert W. Taylor,Rita Horváth	55
18	Mitochondrial DNA mutations and human disease 2009 ·Biochimica et Biophysica Acta (BBA) - Bioenergetics ·Helen Tuppen,Emma L. Blakely,Douglass M. Turnbull,Robert W. Taylor	480
19	Further pitfalls in the diagnosis of mtDNA mutations: homoplasmic mt-tRNA mutations 2008 ·Journal of Medical Genetics ·Helen Tuppen,Fabiana Fattori,Rosalba Carrozzo,Massimo Zeviani,S. DiMauro,Sara Seneca,Joanne Martindale,(unknown),Eileen P. Treacy,Robert McFarland,Filippo M. Santorelli,Rachael W. Taylor	12
20	Overexpression of human mitochondrial valyl tRNA synthetase can partially restore levels of cognate mt-tRNAVal carrying the pathogenic C25U mutation 2008 ·Nucleic Acids Research ·Joanna Rorbach,Abdul Aziz Mohamed Yusoff,Helen Tuppen,(unknown),Zofia M. Chrzanowska‐Lightowlers,Robert W. Taylor,Douglass M. Turnbull,Robert McFarland,Robert N. Lightowlers	66

About Helen Tuppen

Helen Tuppen is a scholar working on Clinical Biochemistry, Molecular Biology and Cellular and Molecular Neuroscience, having authored 34 papers that have together received 1.7k indexed citations. Recurring topics across this work include Mitochondrial Function and Pathology (31 papers), Metabolism and Genetic Disorders (21 papers) and ATP Synthase and ATPases Research (11 papers). The work is most often cited by research in Clinical Biochemistry (721 citations), Aging (42 citations) and Molecular Biology (1.5k citations). Helen Tuppen has collaborated with scholars based in United Kingdom, Italy and United States. Frequent co-authors include Robert W. Taylor, Douglass M. Turnbull, Emma L. Blakely, Robert N. Lightowlers, Patrick F. Chinnery, Julie L. Murphy, Gareth D. Greggains, Lyndsey Craven, Mary Herbert and Alison Murdoch. Their work appears in journals such as Nature, Nucleic Acids Research and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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