Hélder A. Santos

29.4k total citations · 8 hit papers
452 papers, 22.4k citations indexed

About

Hélder A. Santos is a scholar working on Biomedical Engineering, Biomaterials and Molecular Biology. According to data from OpenAlex, Hélder A. Santos has authored 452 papers receiving a total of 22.4k indexed citations (citations by other indexed papers that have themselves been cited), including 199 papers in Biomedical Engineering, 153 papers in Biomaterials and 129 papers in Molecular Biology. Recurrent topics in Hélder A. Santos's work include Nanoparticle-Based Drug Delivery (87 papers), Nanoplatforms for cancer theranostics (75 papers) and Silicon Nanostructures and Photoluminescence (56 papers). Hélder A. Santos is often cited by papers focused on Nanoparticle-Based Drug Delivery (87 papers), Nanoplatforms for cancer theranostics (75 papers) and Silicon Nanostructures and Photoluminescence (56 papers). Hélder A. Santos collaborates with scholars based in Finland, Netherlands and China. Hélder A. Santos's co-authors include Jouni Hirvonen, Hongbo Zhang, Mohammad‐Ali Shahbazi, Jarno Salonen, Ermei Mäkilä, Dongfei Liu, Patrícia Figueiredo, Alexandra Correia, Flavia Fontana and Bruno Sarmento and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Chemical Society Reviews and Advanced Materials.

In The Last Decade

Hélder A. Santos

439 papers receiving 22.2k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Properties and chemical modifications of lignin: Towards lignin-based nanomaterials for biomedical applications

2017 707 citations Patrícia Figueiredo, Jouni Hirvonen et al. profile →
Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy

2019 679 citations Tuying Yong, Xiaoqiong Zhang et al. Nature Communications profile →
The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties

2020 397 citations Mohammad‐Ali Shahbazi, Patrícia Figueiredo et al. profile →
Engineered Extracellular Vesicles for Cancer Therapy

2021 342 citations Xu Zhang, Hongbo Zhang et al. profile →
Selenium Nanoparticles for Biomedical Applications: From Development and Characterization to Therapeutics

2021 316 citations Hélder A. Santos et al. profile →
A Hydrogen‐Bonded Extracellular Matrix‐Mimicking Bactericidal Hydrogel with Radical Scavenging and Hemostatic Function for pH‐Responsive Wound Healing Acceleration

2020 312 citations Alexandra Correia, Patrícia Figueiredo et al. profile →
In vitro evaluation of biodegradable lignin-based nanoparticles for drug delivery and enhanced antiproliferation effect in cancer cells

2017 294 citations Patrícia Figueiredo, Zehua Liu et al. profile →
Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy

2022 209 citations Hongbo Zhang, Hélder A. Santos et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hélder A. Santos Finland	84	10.4k	7.3k	5.9k	5.1k	2.7k	452	22.4k
Zhiyong Qian China	77	9.3k 0.9×	8.2k 1.1×	5.0k 0.8×	2.7k 0.5×	2.2k 0.8×	445	20.2k
Lin Mei China	73	9.8k 0.9×	7.0k 1.0×	6.0k 1.0×	5.4k 1.1×	1.6k 0.6×	276	20.0k
Abolfazl Akbarzadeh Iran	61	6.0k 0.6×	5.9k 0.8×	4.9k 0.8×	4.2k 0.8×	1.5k 0.5×	260	17.6k
Jouni Hirvonen Finland	76	6.9k 0.7×	5.2k 0.7×	3.6k 0.6×	4.9k 1.0×	3.9k 1.4×	336	17.9k
Wei Tao China	91	12.9k 1.2×	7.1k 1.0×	9.3k 1.6×	7.8k 1.5×	1.1k 0.4×	273	26.1k
Xiangliang Yang China	85	11.4k 1.1×	6.4k 0.9×	7.2k 1.2×	6.5k 1.3×	3.4k 1.2×	510	25.5k
Chenjie Xu Singapore	62	6.2k 0.6×	4.1k 0.6×	3.9k 0.7×	4.9k 1.0×	2.4k 0.9×	223	15.5k
Hongbo Zhang China	71	7.1k 0.7×	3.6k 0.5×	6.0k 1.0×	3.2k 0.6×	738 0.3×	507	18.4k
Jianxun Ding China	84	10.5k 1.0×	10.3k 1.4×	5.6k 0.9×	2.5k 0.5×	1.3k 0.5×	359	22.6k
Zhongwei Gu China	78	9.0k 0.9×	9.0k 1.2×	6.4k 1.1×	3.5k 0.7×	858 0.3×	464	20.1k

Countries citing papers authored by Hélder A. Santos

Since Specialization

Citations

This map shows the geographic impact of Hélder A. Santos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hélder A. Santos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hélder A. Santos more than expected).

Fields of papers citing papers by Hélder A. Santos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hélder A. Santos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hélder A. Santos. The network helps show where Hélder A. Santos may publish in the future.

Co-authorship network of co-authors of Hélder A. Santos

This figure shows the co-authorship network connecting the top 25 collaborators of Hélder A. Santos. A scholar is included among the top collaborators of Hélder A. Santos based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hélder A. Santos. Hélder A. Santos is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Yu, Dan, Jianmei Gu, Maoye Wang, et al.. (2025). Integrated Microfluidic Chip for Neutrophil Extracellular Vesicle Analysis and Gastric Cancer Diagnosis. ACS Nano. 19(10). 10078–10092. 11 indexed citations

Ding, Yaping, Yao Huang, Fucheng Zhang, et al.. (2025). Biological Augmentation Using Electrospun Constructs with Dual Growth Factor Release for Rotator Cuff Repair. ACS Applied Bio Materials. 8(3). 2548–2557. 1 indexed citations

Gao, Han, Ruoyu Cheng, Idaira Pacheco‐Fernández, et al.. (2025). Engineered Shape-Tunable Copper-Coordinated Nanoparticles for Macrophage Reprogramming. Nano Letters. 25(7). 2831–2840. 2 indexed citations

Prencipe, Giuseppe, Alexandra Correia, Sami Hietala, et al.. (2025). Development of Amniotic Epithelial Stem Cells Secretome-Loaded In Situ Inverse Electron Demand Diels–Alder-Cross-Linked Hydrogel as a Potential Immunomodulatory Therapeutical Tool. ACS Applied Materials & Interfaces. 17(2). 2977–2990. 1 indexed citations

Han, Huijie, Shiqi Wang, Mohammad‐Ali Shahbazi, et al.. (2024). Reactive oxygen species switcher via MnO2-coated Prussian blue loaded hyaluronic acid methacrylate hydrogel microspheres for local anti-tumor treatment. Journal of Controlled Release. 378. 350–364. 5 indexed citations

Guillot, Antonio José, et al.. (2024). Cyclosporin A-loaded dissolving microneedles for dermatitis therapy: Development, characterisation and efficacy in a delayed-type hypersensitivity in vivo model. Drug Delivery and Translational Research. 14(12). 3404–3421. 6 indexed citations

Wang, Shiqi, Flavia Fontana, Alexandra Correia, et al.. (2023). Fabrication of hydrogel microspheres via microfluidics using inverse electron demand Diels–Alder click chemistry-based tetrazine-norbornene for drug delivery and cell encapsulation applications. Biomaterials Science. 11(14). 4972–4984. 20 indexed citations

Paudel, Keshav Raj, Rashi Rajput, Sachin Kumar Singh, et al.. (2023). Emerging applications and prospects of NFκB decoy oligodeoxynucleotides in managing respiratory diseases. Chemico-Biological Interactions. 385. 110737–110737. 8 indexed citations

Cheng, Ruoyu, Shiqi Wang, & Hélder A. Santos. (2023). Acid-labile chemical bonds-based nanoparticles for endosome escape and intracellular delivery. SHILAP Revista de lepidopterología. 3. 52–58. 21 indexed citations

10.

Santos, Hélder A., et al.. (2020). The Aortomitral Continuity Challenge. 5(1).

11.

Yong, Tuying, Xiaoqiong Zhang, Nana Bie, et al.. (2019). Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy. Nature Communications. 10(1). 3838–3838. 679 indexed citations breakdown →

12.

Qiao, Yue, Ping Yuan, Hongbo Zhang, et al.. (2019). Laser-Activatable CuS Nanodots to Treat Multidrug-Resistant Bacteria and Release Copper Ion to Accelerate Healing of Infected Chronic Nonhealing Wounds. ACS Applied Materials & Interfaces. 11(4). 3809–3822. 195 indexed citations

13.

Khan, Daulat Haleem, Sajid Bashir, Alexandra Correia, et al.. (2019). Utilization of green formulation technique and efficacy estimation on cell line studies for dual anticancer drug therapy with niosomes. International Journal of Pharmaceutics. 572. 118764–118764. 18 indexed citations

14.

Ji, Jianfeng, Fei Ma, Hongbo Zhang, et al.. (2018). Light‐Activatable Assembled Nanoparticles to Improve Tumor Penetration and Eradicate Metastasis in Triple Negative Breast Cancer. Advanced Functional Materials. 28(33). 42 indexed citations

15.

Liu, Zehua, Lina Baranauskienė, Ermei Mäkilä, et al.. (2017). A Versatile Carbonic Anhydrase IX Targeting Ligand-Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging. ACS Applied Materials & Interfaces. 9(16). 13976–13987. 42 indexed citations

16.

Liu, Dongfei, Hongbo Zhang, Flavia Fontana, Jouni Hirvonen, & Hélder A. Santos. (2017). Microfluidic-assisted fabrication of carriers for controlled drug delivery. Lab on a Chip. 17(11). 1856–1883. 199 indexed citations

17.

Liu, Dongfei, Hongbo Zhang, Flavia Fontana, Jouni Hirvonen, & Hélder A. Santos. (2017). Current developments and applications of microfluidic technology toward clinical translation of nanomedicines. Advanced Drug Delivery Reviews. 128. 54–83. 182 indexed citations

18.

Zhang, Feng, Alexandra Correia, Ermei Mäkilä, et al.. (2017). Receptor-Mediated Surface Charge Inversion Platform Based on Porous Silicon Nanoparticles for Efficient Cancer Cell Recognition and Combination Therapy. ACS Applied Materials & Interfaces. 9(11). 10034–10046. 48 indexed citations

19.

Santos, Hélder A.. (2015). Opinion Paper: Microfluidics Technique to Revolutionize the Drug Delivery Field: Current Developments and Applications. Current Drug Delivery. 12(6). 642–644. 1 indexed citations

20.

Limnell, Tarja, Ermei Mäkilä, T. Heikkilä, et al.. (2011). Preparation and characterization of drug formulations of ordered and nonordered mesoporous silica microparticles. European Journal of Pharmaceutical Sciences. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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