Heidrun Interthal

2.8k total citations
27 papers, 2.4k citations indexed

About

Heidrun Interthal is a scholar working on Molecular Biology, Oncology and Toxicology. According to data from OpenAlex, Heidrun Interthal has authored 27 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 5 papers in Oncology and 5 papers in Toxicology. Recurrent topics in Heidrun Interthal's work include Cancer therapeutics and mechanisms (17 papers), DNA Repair Mechanisms (7 papers) and Bioactive Compounds and Antitumor Agents (5 papers). Heidrun Interthal is often cited by papers focused on Cancer therapeutics and mechanisms (17 papers), DNA Repair Mechanisms (7 papers) and Bioactive Compounds and Antitumor Agents (5 papers). Heidrun Interthal collaborates with scholars based in United States, United Kingdom and Germany. Heidrun Interthal's co-authors include James J. Champoux, Wolf‐Dietrich Heyer, Wim G. J. Hol, D.R. Davies, Jeffrey J. Pouliot, Paul Shanahan, Antonia Lopez‐Girona, Michael N. Boddy, Paul Russell and Thomas E. Kehl‐Fie and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Heidrun Interthal

27 papers receiving 2.4k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Heidrun Interthal United States 22 2.2k 552 307 241 239 27 2.4k
Ole Westergaard Denmark 37 3.4k 1.5× 965 1.7× 340 1.1× 79 0.3× 669 2.8× 92 3.6k
Christine Jaxel France 24 1.8k 0.8× 605 1.1× 193 0.6× 40 0.2× 395 1.7× 44 2.0k
Bryan H. Thurtle-Schmidt United States 8 1.3k 0.6× 259 0.5× 192 0.6× 267 1.1× 219 0.9× 12 1.4k
Warren J. Rocque United States 21 1.6k 0.7× 395 0.7× 311 1.0× 41 0.2× 36 0.2× 28 2.0k
S.M. Soisson United States 19 1.1k 0.5× 192 0.3× 277 0.9× 27 0.1× 63 0.3× 32 1.6k
James C. Burnett United States 26 928 0.4× 241 0.4× 427 1.4× 58 0.2× 70 0.3× 57 1.9k
Darcie J. Miller United States 23 1.6k 0.7× 442 0.8× 113 0.4× 120 0.5× 15 0.1× 48 2.0k
Stephen A. Margosiak United States 21 925 0.4× 358 0.6× 351 1.1× 177 0.7× 14 0.1× 28 1.6k
Dindial Ramotar Canada 30 2.5k 1.1× 372 0.7× 53 0.2× 248 1.0× 17 0.1× 115 2.9k
Tamio Mizukami Japan 26 1.8k 0.8× 260 0.5× 371 1.2× 206 0.9× 49 0.2× 76 2.5k

Countries citing papers authored by Heidrun Interthal

Since Specialization
Citations

This map shows the geographic impact of Heidrun Interthal's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Heidrun Interthal with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Heidrun Interthal more than expected).

Fields of papers citing papers by Heidrun Interthal

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Heidrun Interthal. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Heidrun Interthal. The network helps show where Heidrun Interthal may publish in the future.

Co-authorship network of co-authors of Heidrun Interthal

This figure shows the co-authorship network connecting the top 25 collaborators of Heidrun Interthal. A scholar is included among the top collaborators of Heidrun Interthal based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Heidrun Interthal. Heidrun Interthal is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Flett, Fiona, Lee A. Armstrong, E.R. Morris, et al.. (2017). Structural basis for DNA 3′-end processing by human tyrosyl-DNA phosphodiesterase 1. Nature Communications. 9(1). 24–24. 31 indexed citations
2.
Flett, Fiona, et al.. (2015). Click Chemistry Generated Model DNA–Peptide Heteroconjugates as Tools for Mass Spectrometry. Analytical Chemistry. 87(19). 9595–9599. 7 indexed citations
3.
Dean, Richard A., Jianghong An, Kunho Choi, et al.. (2014). Identification of a Putative Tdp1 Inhibitor (CD00509) by in Vitro and Cell-Based Assays. SLAS DISCOVERY. 19(10). 1372–1382. 41 indexed citations
4.
Flett, Fiona & Heidrun Interthal. (2013). Separation of DNA Oligonucleotides Using Denaturing Urea PAGE. Methods in molecular biology. 1054. 173–185. 4 indexed citations
5.
Interthal, Heidrun & James J. Champoux. (2011). Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1. Biochemical Journal. 436(3). 559–566. 44 indexed citations
6.
Walton, Cheryl, Heidrun Interthal, Ryuki Hirano, et al.. (2010). Spinocerebellar Ataxia with Axonal Neuropathy. Advances in experimental medicine and biology. 685. 75–83. 7 indexed citations
7.
Amaro, Rommie E., Achim Schnaufer, Heidrun Interthal, et al.. (2008). Discovery of drug-like inhibitors of an essential RNA-editing ligase in Trypanosoma brucei. Proceedings of the National Academy of Sciences. 105(45). 17278–17283. 107 indexed citations
8.
Hirano, Ryuki, Heidrun Interthal, Cheng Huang, et al.. (2007). Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?. The EMBO Journal. 26(22). 4732–4743. 116 indexed citations
9.
Davies, D.R., Adeel Mushtaq, Heidrun Interthal, James J. Champoux, & Wim G. J. Hol. (2006). The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA. Journal of Molecular Biology. 357(4). 1202–1210. 70 indexed citations
10.
Interthal, Heidrun, et al.. (2005). SCAN1 mutant Tdp1 accumulates the enzyme–DNA intermediate and causes camptothecin hypersensitivity. The EMBO Journal. 24(12). 2224–2233. 177 indexed citations
11.
Interthal, Heidrun, et al.. (2005). Human Tdp1 Cleaves a Broad Spectrum of Substrates, Including Phosphoamide Linkages. Journal of Biological Chemistry. 280(43). 36518–36528. 188 indexed citations
12.
Barthelmes, Hans, Michael Habermeyer, Morten O. Christensen, et al.. (2004). TDP1 Overexpression in Human Cells Counteracts DNA Damage Mediated by Topoisomerases I and II. Journal of Biological Chemistry. 279(53). 55618–55625. 122 indexed citations
13.
Davies, D.R., Heidrun Interthal, James J. Champoux, & Wim G. J. Hol. (2004). Explorations of Peptide and Oligonucleotide Binding Sites of Tyrosyl-DNA Phosphodiesterase Using Vanadate Complexes. Journal of Medicinal Chemistry. 47(4). 829–837. 46 indexed citations
14.
Interthal, Heidrun, et al.. (2004). The Role of Lysine 532 in the Catalytic Mechanism of Human Topoisomerase I. Journal of Biological Chemistry. 279(4). 2984–2992. 38 indexed citations
15.
Davies, D.R., Heidrun Interthal, James J. Champoux, & Wim G. J. Hol. (2003). Crystal Structure of a Transition State Mimic for Tdp1 Assembled from Vanadate, DNA, and a Topoisomerase I-Derived Peptide. Chemistry & Biology. 10(2). 139–147. 113 indexed citations
16.
Davies, D.R., Heidrun Interthal, James J. Champoux, & Wim G. J. Hol. (2002). The Crystal Structure of Human Tyrosyl-DNA Phosphodiesterase, Tdp1. Structure. 10(2). 237–248. 148 indexed citations
17.
Davies, D.R., Heidrun Interthal, James J. Champoux, & Wim G. J. Hol. (2002). Insights into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate and Tungstate-inhibited Structures. Journal of Molecular Biology. 324(5). 917–932. 114 indexed citations
18.
Interthal, Heidrun & Wolf‐Dietrich Heyer. (2000). MUS81 encodes a novel Helix-hairpin-Helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae. Molecular and General Genetics MGG. 263(5). 812–827. 188 indexed citations
19.
Interthal, Heidrun, et al.. (1995). A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae.. The EMBO Journal. 14(6). 1057–1066. 54 indexed citations
20.
Seyfert, Hans‐Martin, et al.. (1993). Definition, distribution, and use of a conserved Bovidae retroposon element sequence motif. Mammalian Genome. 4(3). 153–158. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Ole Westergaard Breakdown of academic impact, for papers by Christine Jaxel Breakdown of academic impact, for papers by Bryan H. Thurtle-Schmidt Breakdown of academic impact, for papers by Warren J. Rocque Breakdown of academic impact, for papers by S.M. Soisson Breakdown of academic impact, for papers by James C. Burnett Breakdown of academic impact, for papers by Darcie J. Miller Breakdown of academic impact, for papers by Stephen A. Margosiak Breakdown of academic impact, for papers by Dindial Ramotar Breakdown of academic impact, for papers by Tamio Mizukami
Rankless by CCL
2026