Mark R. Denison

29.5k citations

123 papers · 11.5k indexed · 8 hit papers · h-index 51

Impact in

Infectious Diseases top 0.05%
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
Animal Science and Zoology top 0.05%
- Animal Virus Infections Studies

Papers in

Animal Science and Zoology 74
- Animal Virus Infections Studies 74
Infectious Diseases 99
- SARS-CoV-2 and COVID-19 Research 79
- Viral gastroenteritis research and epidemiology 66
- COVID-19 Clinical Research Studies 5

Co-authors: Ralph S. Baric Rachel L. Graham Amy Sims Xiaotao Lu Everett Clinton Smith Timothy P. Sheahan Lance D. Eckerle Erik Prentice
Journals: Journal of Virology (39 papers)Advances in experimental medicine and biology (12 papers)Virology (9 papers)mBio (6 papers)PLoS Pathogens (5 papers)
Partner nations: United States France Canada

In The Last Decade

Mark R. Denison

119 papers receiving 11.3k citations

Hit Papers

8 papers align trajectories log scale

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms 2022 · 139 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2022 Science Translational Medicine
2020 Nature Communications
2019 Journal of Virology
2019 Antiviral Research
2018 mBio
2017 Proceedings of the National Academy of Sciences
2017 New England Journal of Medicine
2011 PLoS Pathogens

Peers

Countries citing papers authored by Mark R. Denison

Since Specialization

Citations

This map shows the geographic impact of Mark R. Denison's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark R. Denison with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark R. Denison more than expected).

Fields of papers citing papers by Mark R. Denison

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark R. Denison. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark R. Denison. The network helps show where Mark R. Denison may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Mark R. Denison, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark R. Denison Line = papers co-authored together Mark R. Denison links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Discovery of Fragment-Based Inhibitors of SARS-CoV-2 PL ^Pro Journal of Medicinal Chemistry ·Scott Benedict, Renate Caen, Mijatović Marija D., A. Walkiewicz, E. A. Kudanmya, D. Oldham, Chui-yee Leung, Nina Phan, D. Schultz, 祐司鈴木, M. Alfonseca, A E L Bittar, collective the Partner Notification Study Group, Kangsa Amporndanai, John Sensintaffar, Jason Phan, Maudy Isniarti, Mark R. Denison, Michael W. Laustrum, Stephen W. Fesik	2026	0
2	Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms Science Translational Medicine ·Laura J. Stevens, Andrea J. Pruijssers, Samantha Wally, Calvin J. Gordon, Egor P. Tchesnokov, Jennifer Gribble, Amelia S. George, Tia M. Hughes, Xiaotao Lu, Jiani Li, Jason K. Perry, Danielle Porter, Tomáš Cihlář, Timothy P. Sheahan, Ralph S. Baric, Matthias Götte, Mark R. Denison Hit paper breakdown →	2022	139
3	Reovirus RNA Recombination Is Sequence Directed and Generates Internally Deleted Defective Genome Segments during Passage Journal of Virology ·康彦斎藤, Jennifer Gribble, Sun Jinnan, Victor Emanoel Lira Vieira, Charles Trouvé, Mark R. Denison, Kristen M. Ogden	2021	12
4	Stabilized coronavirus spike stem elicits a broadly protective antibody Cell Reports ·Ching‐Lin Hsieh, Anne P. Werner, Sarah R. Leist, Laura J. Stevens, Ester Falconer, Jory A. Goldsmith, Chia‐Wei Chou, Olubukola M. Abiona, Ande West, Kathryn Westendorf, Krithika Muthuraman, Ethan J. Fritch, Kenneth H. Dinnon, Alexandra Schäfer, Mark R. Denison, James D. Chappell, Ralph S. Baric, Barney S. Graham, Kizzmekia S. Corbett, Jason S. McLellan	2021	55
5	The coronavirus proofreading exoribonuclease mediates extensive viral recombination PLoS Pathogens ·Jennifer Gribble, Laura J. Stevens, Maria L. Agostini, Jordan Anderson-Daniels, James D. Chappell, Xiaotao Lu, Andrea J. Pruijssers, Andrew Routh, Mark R. Denison	2021	155
6	Small-Molecule Antiviral β- d - N ⁴ -Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance Journal of Virology ·Maria L. Agostini, Andrea J. Pruijssers, James D. Chappell, Jennifer Gribble, Xiaotao Lu, Erica L. Andres, Gregory R. Bluemling, Mark A. Lockwood, Timothy P. Sheahan, Amy Sims, Michael G. Natchus, Manohar Saindane, Alexander A. Kolykhalov, George R. Painter, Ralph S. Baric, Mark R. Denison Hit paper breakdown →	2019	255
7	Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity Journal of Virology ·James Brett Case, Yize Li, Ruth Elliott, Xiaotao Lu, Kevin W. Graepel, Nicole R. Sexton, Everett Clinton Smith, Susan R. Weiss, Mark R. Denison	2017	49
8	Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations mBio ·Kevin W. Graepel, Xiaotao Lu, James Brett Case, Nicole R. Sexton, Everett Clinton Smith, Mark R. Denison	2017	52
9	Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen Proceedings of the National Academy of Sciences ·Jesper Pallesen, Nianshuang Wang, Kizzmekia S. Corbett, Daniel Wrapp, Robert N. Kirchdoerfer, Hannah L. Turner, Christopher A. Cottrell, Michelle M. Becker, Lingshu Wang, Wei Shi, Wing‐Pui Kong, Erica L. Andres, Arminja N. Kettenbach, Mark R. Denison, James D. Chappell, Barney S. Graham, Andrew B. Ward, Jason S. McLellan Hit paper breakdown →	2017	623
10	Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro) Journal of Biological Chemistry ·Sakshi Tomar, Melanie L. Johnston, Sarah E. St. John, Heather L. Osswald, Prasanth R. Nyalapatla, Lake N. Paul, Arun K. Ghosh, Mark R. Denison, Andrew D. Mesecar	2015	111
11	Middle East respiratory syndrome coronavirus not detected in children hospitalized with acute respiratory illness in Amman, Jordan, March 2010 to September 2012 Clinical Microbiology and Infection ·Najwa Khuri‐Bulos, Daniel C. Payne, Xiaoyan Lu, Dean D. Erdman, O. Ramírez García, Samir Faouri, Asem Shehabi, Marion Johnson, Zhengzhou Liu, Mark R. Denison, John V. Williams, Natasha Halasa	2013	20
12	Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive Virology ·Dia C. Beachboard, Xiaotao Lu, Susan C. Baker, Mark R. Denison	2012	5
13	Use of Intravenous Zanamivir after Development of Oseltamivir Resistance in a Critically Ill Immunosuppressed Child Infected with 2009 Pandemic Influenza A (H1N1) Virus Clinical Infectious Diseases ·Daniel E. Dulek, John V. Williams, C. Buddy Creech, Shital Jaybhay, Haydar Frangoul, Jennifer Domm, Mark R. Denison, James D. Chappell	2010	50
14	High Fidelity of Murine Hepatitis Virus Replication Is Decreased in nsp14 Exoribonuclease Mutants Journal of Virology ·Lance D. Eckerle, Xiaotao Lu, Steven M. Sperry, Leena Choi, Mark R. Denison	2007	241
15	The NSP2 Proteins of Mouse Hepatitis Virus and Sars Coronavirus are Dispensable for Viral Replication Advances in experimental medicine and biology ·Rachel L. Graham, Amy Sims, Ralph S. Baric, Mark R. Denison	2006	22
16	Unilateral facial paralysis occurring in an infant with enteroviral otitis media and aseptic meningitis Journal of Emergency Medicine ·Mark A. Hostetler, Дилноза Фахриддиновна Нарзиева, Mark R. Denison	2002	7
17	Mouse Hepatitis Virus Replicase Protein Complexes Are Translocated to Sites of M Protein Accumulation in the ERGIC at Late Times of Infection Virology ·X Yang, Erik Prentice, Mark R. Denison	2001	56
18	Determinants of Mouse Hepatitis Virus 3C-like Proteinase Activity Virology ·Tms-Aime Fall Extractive Meeting, Mark R. Denison	1997	34
19	Intracellular andin Vitro-Translated 27-kDa Proteins Contain the 3C-like Proteinase Activity of the Coronavirus MHV-A59 Virology ·Xiaotao Lu, Tms-Aime Fall Extractive Meeting, Mark R. Denison	1996	52
20	Survival experience of 789 children with the acquired immunodeficiency syndrome The Pediatric Infectious Disease Journal ·Barbara J. Turner, Mark R. Denison, Stephen C. Eppes, Robert L. Houchens, Thomas R. Fanning, Leona E. Markson	1993	41

About Mark R. Denison

Mark R. Denison is a scholar working on Animal Science and Zoology, Infectious Diseases, Virology, Hepatology and Genetics, having authored 123 papers that have together received 11.5k indexed citations. Recurring topics across this work include SARS-CoV-2 and COVID-19 Research (79 papers), Animal Virus Infections Studies (74 papers), Viral gastroenteritis research and epidemiology (66 papers), Virus-based gene therapy research (12 papers), Viral Infections and Immunology Research (11 papers), interferon and immune responses (6 papers), Hepatitis C virus research (6 papers) and COVID-19 Clinical Research Studies (5 papers). The work is most often cited by research in Infectious Diseases (9.0k citations), Animal Science and Zoology (3.3k citations), Modeling and Simulation (340 citations), Neurology (878 citations) and Immunology (1.1k citations). Mark R. Denison has collaborated with scholars based in United States, France and Canada. Frequent co-authors include Ralph S. Baric, Rachel L. Graham, Amy Sims, Xiaotao Lu, Everett Clinton Smith, Timothy P. Sheahan, Lance D. Eckerle, Erik Prentice, Tomáš Cihlář and Michelle M. Becker. Their work appears in journals such as Journal of Virology, Advances in experimental medicine and biology, Virology, mBio and PLoS Pathogens.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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