Guoan Chen

13.9k citations

199 papers · 10.2k indexed · 4 hit papers · h-index 51

Impact in

Cancer Research top 0.2%
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Cancer Genomics and Diagnostics
Molecular Biology top 0.5%
- RNA modifications and cancer
- Circular RNAs in diseases
- Gene expression and cancer classification
- Epigenetics and DNA Methylation

Papers in

Cancer Research 54
- Cancer-related molecular mechanisms research 31
- MicroRNA in disease regulation 18
Mechanics of Materials 44
- Mechanical stress and fatigue analysis 22

Co-authors: David G. Beer Thomas J. Giordano Mark B. Orringer Dafydd G. Thomas Jeremy M. G. Taylor Samir Hanash David E. Misek Tarek G. Gharib
Journals: Cancer Research (9 papers)Wear (7 papers)Clinical Cancer Research (6 papers)Journal of Thoracic Oncology (5 papers)Neoplasia (4 papers)
Partner nations: China United States Australia

In The Last Decade

Guoan Chen

196 papers receiving 9.9k citations

Hit Papers

align trajectories log scale

HDAC2‐Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple‐Negative Breast Cancer 2025 · 19 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2025 Advanced Science
2023 Cell Communication and Signaling
2002 Nature Medicine
2002 Molecular & Cellular Proteomics

Peers

Countries citing papers authored by Guoan Chen

Since Specialization

Citations

This map shows the geographic impact of Guoan Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Guoan Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Guoan Chen more than expected).

Fields of papers citing papers by Guoan Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Guoan Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Guoan Chen. The network helps show where Guoan Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Guoan Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Guoan Chen Line = papers co-authored together Guoan Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Suppression of the long non-coding RNA LINC01279 triggers autophagy and apoptosis in lung cancer by regulating FAK and SIN3A Discover Oncology ·Christoph Amy L. McDoniels-Silvers, Xiaobi Huang, Xiaofang Li, A Bravo-Blas, А А Чатинян, Yongyang Chen, Yanagiuchi Akihiro, Jian Huang, 秀樹津村, Zhong Huang, Guoan Chen, Sonali Rehil, Jian Zhang, Wenmei Su	2024	5
2	Application of single-cell sequencing to the research of tumor microenvironment Frontiers in Immunology ·YU Xue-tin, شعله راهبی, Yu Li, Yuhui Du, Guoan Chen	2023	24
3	Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer Cancer Research ·Wenmei Su, Ruth Levinson, Xiuyuan Chen, Xia Yang, Rui Mao, Chunfang Guo, Zhuwen Wang, Dafydd G. Thomas, Jules Lin, Rishindra M. Reddy, Mark B. Orringer, Andrew C. Chang, Zhixiong Yang, David G. Beer, Guoan Chen	2018	119
4	Overexpression of FAM83H-AS1 indicates poor patient survival and knockdown impairs cell proliferation and invasion via MET/EGFR signaling in lung cancer Scientific Reports ·Jie Zhang, Ruth Levinson, Wenmei Su, R. Bermejo, Lei Xiao, Lihui Wang, Dafydd G. Thomas, Jules Lin, Rishindra M. Reddy, Philip W. Carrott, William R. Lynch, Andrew C. Chang, David G. Beer, إياد طه الرواشدة, Guoan Chen	2017	43
5	Fault diagnosis of rotating machinery based on noise reduction using empirical mode decomposition and singular value decomposition Journal of Vibroengineering ·Fan Jiang, Zhencai Zhu, Wei Li, Gongbo Zhou, Guoan Chen	2015	8
6	A Novel Serum 4-microRNA Signature for Lung Cancer Detection Scientific Reports ·Ernest Nadal, Anna Truini, Asuka Nakata, Jules Lin, Rishindra M. Reddy, Andrew C. Chang, Nithya Ramnath, Noriko Gotoh, David G. Beer, Guoan Chen	2015	108
7	A MicroRNA Cluster at 14q32 Drives Aggressive Lung Adenocarcinoma Clinical Cancer Research ·Ernest Nadal, Jinjie Zhong, Jules Lin, Rishindra M. Reddy, Nithya Ramnath, Mark B. Orringer, Andrew C. Chang, David G. Beer, Guoan Chen	2014	85
8	The probabilistic modeling and reliability analysis of brake shoes for hoist disc brake with correlated failure modes Advances in Mechanical Engineering ·Nahiro Uraoka, Guoan Chen, Gao Yana, M. TISLER	2014	4
9	Epigenetic Inactivation of microRNA-34b/c Predicts Poor Disease-Free Survival in Early-Stage Lung Adenocarcinoma Clinical Cancer Research ·Ernest Nadal, Guoan Chen, Priputnevich T.V. Priputnevich, Lin Lin, Daysha Ferrer-Torres, Anna Truini, Zhuwen Wang, Jules Lin, Rishindra M. Reddy, Roger Llatjós, Ignacio Escobar, Juan Moya, Andrew C. Chang, Felipe Cardenal, Gabriel Capellá, David G. Beer	2013	53
10	Integrated design of fault detection for LTI systems: An iterative LMI approach Chinese Control Conference ·Wei Li, Zhencai Zhu, Gongbo Zhou, Guoan Chen	2013	1
11	Stromal LRP1 in Lung Adenocarcinoma Predicts Clinical Outcome Clinical Cancer Research ·He Meng, Guoan Chen, Xiaojie Zhang, Zhuwen Wang, Dafydd G. Thomas, Thomas J. Giordano, David G. Beer, Michael M. Wang	2011	35
12	CYP24A1 Is an Independent Prognostic Marker of Survival in Patients with Lung Adenocarcinoma Clinical Cancer Research ·Guoan Chen, So Hee Kim, Amanda N. King, Lili Zhao, Robert U. Simpson, Paul J. Christensen, Zhuwen Wang, Dafydd G. Thomas, Thomas J. Giordano, Lin Lin, Dean E. Brenner, David G. Beer, Nithya Ramnath	2010	85
13	MicroRNA Classifiers for Predicting Prognosis of Squamous Cell Lung Cancer Cancer Research ·Mitch Raponi, Lesley Dossey, Tim Jatkoe, Xiaoying Wu, Guoan Chen, Hongtao Fan, David G. Beer	2009	333
14	An Embryonic Stem Cell–Like Signature Identifies Poorly Differentiated Lung Adenocarcinoma but not Squamous Cell Carcinoma Clinical Cancer Research ·Khaled A. Hassan, Guoan Chen, Gregory P. Kalemkerian, Max S. Wicha, David G. Beer	2009	51
15	Tribological behaviors of asbestos-free brake shoes for hoist winder disc brakes Ha'erbin gongye daxue xuebao ·Guoan Chen	2008	7
16	Simulation and Experimental Research on Three Dimensional Transient Temperature Field of Brake Shoe for Winder Disc Brake Tribology ·Guoan Chen	2008	3
17	Autoantibody Profiles Reveal Ubiquilin 1 as a Humoral Immune Response Target in Lung Adenocarcinoma Cancer Research ·Guoan Chen, Xiaoju Wang, Jianjun Yu, Sooryanarayana Varambally, Jindan Yu, Dafydd G. Thomas, Mu-Yen Lin, Prakash Vishnu, Zhuwen Wang, Rui Wang, E D Putra, Debashis Ghosh, Thomas J. Giordano, Donald Giacherio, Andrew C. Chang, Mark B. Orringer, Talal El‐Hefnawy, William L. Bigbee, David G. Beer, Arul M. Chinnaiyan	2007	73
18	A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome Cancer Research ·Jindan Yu, Jianjun Yu, Daniel R. Rhodes, Scott A. Tomlins, Xuhong Cao, Guoan Chen, Rohit Mehra, Xiaoju Wang, Debashis Ghosh, Rajal B. Shah, Sooryanarayana Varambally, Kenneth J. Pienta, Arul M. Chinnaiyan	2007	251
19	Gene Expression Signatures for Predicting Prognosis of Squamous Cell and Adenocarcinomas of the Lung Cancer Research ·Mitch Raponi, Yi Zhang, Jack X. Yu, Guoan Chen, Grace Lee, Jeremy M. G. Taylor, James W. MacDonald, Dafydd G. Thomas, Christopher A. Moskaluk, Yixin Wang, David G. Beer	2006	319
20	Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas Oncogene ·Charles T. Miller, Guoan Chen, Tarek G. Gharib, Hong Wang, Dafydd G. Thomas, David E. Misek, Thomas J. Giordano, John Yee, Mark B. Orringer, Samir Hanash, David G. Beer	2003	76

About Guoan Chen

Guoan Chen is a scholar working on Cancer Research, Mechanics of Materials, Automotive Engineering, Control and Systems Engineering and Molecular Biology, having authored 199 papers that have together received 10.2k indexed citations. Recurring topics across this work include RNA modifications and cancer (35 papers), Cancer-related molecular mechanisms research (31 papers), Mechanical stress and fatigue analysis (22 papers), MicroRNA in disease regulation (18 papers), Brake Systems and Friction Analysis (15 papers), Lung Cancer Treatments and Mutations (14 papers), Circular RNAs in diseases (13 papers) and Ubiquitin and proteasome pathways (11 papers). The work is most often cited by research in Cancer Research (3.0k citations), Molecular Biology (6.1k citations), Oncology (1.8k citations), Pulmonary and Respiratory Medicine (1.6k citations) and Spectroscopy (506 citations). Guoan Chen has collaborated with scholars based in China, United States and Australia. Frequent co-authors include David G. Beer, Thomas J. Giordano, Mark B. Orringer, Dafydd G. Thomas, Jeremy M. G. Taylor, Samir Hanash, David E. Misek, Tarek G. Gharib, Mark D. Iannettoni and Sharon L. R. Kardia. Their work appears in journals such as Cancer Research, Wear, Clinical Cancer Research, Journal of Thoracic Oncology and Neoplasia.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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