Genta Ito

3.3k citations

43 papers · 2.3k indexed · 1 hit paper · h-index 20

Impact in

Neurology top 0.5%
- Parkinson's Disease Mechanisms and Treatments
- Neurological diseases and metabolism
- Neurological disorders and treatments
Cell Biology top 2%
- Cellular transport and secretion

Papers in ⓘ

Neurology 26
- Parkinson's Disease Mechanisms and Treatments 25
Molecular Biology 15
- Plant Gene Expression Analysis 5
- Retinal Development and Disorders 5
- Fungal and yeast genetics research 3

Co-authors: Takeshi Iwatsubo (15 shared papers)Dario R. Alessi (5 shared papers)Francesca Tonelli (2 shared papers)Alastair D. Reith (2 shared papers)Marco A. S. Baptista (2 shared papers)Graham Duddy (2 shared papers)Stephen Wilson (1 shared paper)Stefanie Wachter (1 shared paper)
Journals: Biochemical and Biophysical Research Communications (4 papers)Biochemical Journal (3 papers)Journal of Biological Chemistry (3 papers)Biochemistry (3 papers)Journal of Visualized Experiments (2 papers)
Partner nations: Japan United States United Kingdom

In The Last Decade

Genta Ito

39 papers receiving 2.3k citations

Hit Papers

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Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases 2016 · 705 citations

Peers

Countries citing papers authored by Genta Ito

Since Specialization

Citations

This map shows the geographic impact of Genta Ito's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Genta Ito with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Genta Ito more than expected).

Fields of papers citing papers by Genta Ito

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Genta Ito. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Genta Ito. The network helps show where Genta Ito may publish in the future.

Co-authors

The 25 scholars most cited alongside Genta Ito, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Genta Ito Line = papers co-authored together Genta Ito links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 43 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases eLife ·Martin Steger, Francesca Tonelli, Genta Ito, Paul Davies, Matthias Trost, Melanie Vetter, Stefanie Wachter, Esben Lorentzen, Graham Duddy, Stephen Wilson, Marco A. S. Baptista, Brian Fiske, Matthew Fell, John A. Morrow, Alastair D. Reith, Dario R. Alessi, Matthias Mann Hit paper breakdown →	2016	705
2	GTP Binding Is Essential to the Protein Kinase Activity of LRRK2, a Causative Gene Product for Familial Parkinson's Disease Biochemistry ·Genta Ito, Takuro Okai, Go Fujino, Kohsuke Takeda, Hidenori Ichijo, Toshiaki Katada, Takeshi Iwatsubo	2007	218
3	LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis Proceedings of the National Academy of Sciences ·Tomoya Eguchi, Tomoki Kuwahara, Maria Sakurai, Tadayuki Komori, Tetta Fujimoto, Genta Ito, Shin‐ichiro Yoshimura, Akihiro Harada, Mitsunori Fukuda, Masato Koike, Takeshi Iwatsubo	2018	212
4	Lewy Body Pathology Involves Cutaneous Nerves Journal of Neuropathology & Experimental Neurology ·Masako Ikemura, Yuko Saito, Renpei Sengoku, Yoshio Sakiyama, Hiroyuki Hatsuta, Kazutomi Kanemaru, Motoji Sawabe, Tomio Arai, Genta Ito, Takeshi Iwatsubo, Masashi Fukayama, Shigeo Murayama	2008	166
5	Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors Biochemical Journal ·Genta Ito, Kristina Katsemonova, Francesca Tonelli, Paweł Lis, Marco A. S. Baptista, Natalia Shpiro, Graham Duddy, Steve Wilson, Philip Wing‐Lok Ho, Shu‐Leong Ho, Alastair D. Reith, Dario R. Alessi	2016	123
6	Analysis of the Adrenal Gland Is Useful for Evaluating Pathology of the Peripheral Autonomic Nervous System in Lewy Body Disease Journal of Neuropathology & Experimental Neurology ·Yuichi Fumimura, Masako Ikemura, Yuko Saito, Renpei Sengoku, Kazutomi Kanemaru, Motoji Sawabe, Tomio Arai, Genta Ito, Takeshi Iwatsubo, Masashi Fukayama, Hidehiro Mizusawa, Shigeo Murayama	2007	107
7	Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils Biochemical Journal ·Ying Fan, Andrew J.M. Howden, Adil R. Sarhan, Paweł Lis, Genta Ito, Terina N. Martinez, Kathrin Brockmann, Thomas Gasser, Dario R. Alessi, Esther Sammler	2017	100
8	Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1 Neuroscience Letters ·Sho Takatori, Genta Ito, Takeshi Iwatsubo	2007	95
9	Identification of the Autophosphorylation Sites of LRRK2 Biochemistry ·Shogo Kamikawaji, Genta Ito, Takeshi Iwatsubo	2009	90
10	Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1 Biochemical and Biophysical Research Communications ·Genta Ito, Hiroyoshi Ariga, Yasuhito Nakagawa, Takeshi Iwatsubo	2005	65
11	Phosphorylation of α-Synuclein Protein at Ser-129 Reduces Neuronal Dysfunction by Lowering Its Membrane Binding Property in Caenorhabditis elegans Journal of Biological Chemistry ·Tomoki Kuwahara, Reina Tonegawa‐Kuji, Genta Ito, Shohei Mitani, Takeshi Iwatsubo	2012	62
12	LRRK2 in Parkinson's disease and dementia with Lewy bodies. Molecular Neurodegeneration ·Xiongwei Zhu, Asim K. Babar, Sandra L. Siedlak, Qiwei Yang, Genta Ito, Takeshi Iwatsubo, Mark A. Smith, George Perry, Shu G. Chen	2006	48
13	Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor ACS Medicinal Chemistry Letters ·John M. Hatcher, Jinwei Zhang, Hwan Geun Choi, Genta Ito, Dario R. Alessi, Nathanael S. Gray	2015	44
14	Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form Biochemical Journal ·Genta Ito, Takeshi Iwatsubo	2011	35
15	Enhanced Accumulation of Phosphorylated α-Synuclein and Elevated β-Amyloid 42/40 Ratio Caused by Expression of the Presenilin-1 ΔT440 Mutant Associated with Familial Lewy Body Disease and Variant Alzheimer's Disease Journal of Neuroscience ·Hiroyuki Kaneko, Akiyoshi Kakita, Kensaku Kasuga, Hiroaki Nozaki, Atsushi Ishikawa, Akinori Miyashita, Ryozo Kuwano, Genta Ito, Takeshi Iwatsubo, Hitoshi Takahashi, Masatoyo Nishizawa, Osamu Onodera, Sangram S. Sisodia, Takeshi Ikeuchi	2007	34
16	Structural Characterization of LRRK2 Inhibitors Journal of Medicinal Chemistry ·Bernd K. Gilsbach, Ana C. Messias, Genta Ito, Michael Sattler, Dario R. Alessi, Alfred Wittinghofer, Arjan Kortholt	2015	28
17	Leucine-Rich Repeat Kinase 2 Colocalizes with α-Synuclein in Parkinson’s Disease, but Not Tau-Containing Deposits in Tauopathies Neurodegenerative Diseases ·George Perry, Xiongwei Zhu, Asim K. Babar, Sandra L. Siedlak, Qiwei Yang, Genta Ito, Takeshi Iwatsubo, Mark A. Smith, Shu G. Chen	2008	25
18	Lack of Correlation between the Kinase Activity of LRRK2 Harboring Kinase-Modifying Mutations and Its Phosphorylation at Ser910, 935, and Ser955 PLoS ONE ·Genta Ito, Tetta Fujimoto, Shogo Kamikawaji, Tomoki Kuwahara, Takeshi Iwatsubo	2014	25
19	The Regulation of Rab GTPases by Phosphorylation Biomolecules ·Lejia Xu, Yuki Nagai, Yotaro Kajihara, Genta Ito, Taisuke Tomita	2021	24
20	INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model iScience ·Akihiro Iguchi, Sho Takatori, Shingo Kimura, Hiroki Muneto, Kai Wang, Hayato Etani, Genta Ito, Haruaki Sato, Yukiko Hori, Junko Sasaki, Takashi Saito, Takaomi C. Saido, Tsuneya Ikezu, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita	2023	19

About Genta Ito

Genta Ito is a scholar working on Neurology, Molecular Biology, Cell Biology, Physiology and Infectious Diseases, having authored 43 papers that have together received 2.3k indexed citations. Recurring topics across this work include Parkinson's Disease Mechanisms and Treatments (25 papers), Cellular transport and secretion (14 papers), Alzheimer's disease research and treatments (7 papers), Lysosomal Storage Disorders Research (5 papers), Plant Gene Expression Analysis (5 papers), Retinal Development and Disorders (5 papers), Animal Virus Infections Studies (3 papers) and Fungal and yeast genetics research (3 papers). The work is most often cited by research in Neurology (1.7k citations), Cell Biology (707 citations), Neurology (352 citations), Physiology (715 citations) and Cellular and Molecular Neuroscience (418 citations). Genta Ito has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Takeshi Iwatsubo, Dario R. Alessi, Francesca Tonelli, Alastair D. Reith, Marco A. S. Baptista, Graham Duddy, Stephen Wilson, Stefanie Wachter, Matthias Trost and Matthew Fell. Their work appears in journals such as Biochemical and Biophysical Research Communications, Biochemical Journal, Journal of Biological Chemistry, Biochemistry and Journal of Visualized Experiments.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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