Fred J.H. Tilders

12.0k citations

163 papers · 9.9k indexed · 2 hit papers · h-index 55

Behavioral Neuroscience top 0.02%
Social Psychology top 0.2%
Cellular and Molecular Neuroscience top 0.5%
Biological Psychiatry top 0.1%
Endocrine and Autonomic Systems top 0.2%

Co-authors: F. Berkenbosch Dick F. Swaab E.D. Schmidt F.C. Raadsheer Adriana del Rey Hugo O. Besedovsky Rob Binnekade Dimphena C.E. de Goeij
Topics: Stress Responses and Cortisol (90 papers)Neuroendocrine regulation and behavior (44 papers)Neuropeptides and Animal Physiology (23 papers)
Cited by: Behavioral Neuroscience Biological Psychiatry Endocrine and Autonomic Systems
Journals: Nature Science The Journal of Experimental Medicine
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Fred J.H. Tilders

162 papers receiving 9.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Corticotropin-Releasing Factor-Producing Neurons in the Rat Activated by Interleukin-1

1987 913 citations F. Berkenbosch, Adriana del Rey et al. profile →
Increased Numbers of Corticotropin-Releasing Hormone Expressing Neurons in the Hypothalamic Paraventricular Nucleus of Depressed Patients

1994 507 citations F.C. Raadsheer, Witte J.G. Hoogendijk et al. Neuroendocrinology profile →

Peers

Countries citing papers authored by Fred J.H. Tilders

Since Specialization

Citations

This map shows the geographic impact of Fred J.H. Tilders's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fred J.H. Tilders with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fred J.H. Tilders more than expected).

Fields of papers citing papers by Fred J.H. Tilders

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fred J.H. Tilders. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fred J.H. Tilders. The network helps show where Fred J.H. Tilders may publish in the future.

Co-authorship network of co-authors of Fred J.H. Tilders

This figure shows the co-authorship network connecting the top 25 collaborators of Fred J.H. Tilders. A scholar is included among the top collaborators of Fred J.H. Tilders based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Fred J.H. Tilders. Fred J.H. Tilders is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Single administration of interleukin-1 increased corticotropin releasing hormone and corticotropin releasing hormone-receptor mRNA in the hypothalamic paraventricular nucleus which paralleled long-lasting (weeks) sensitization to emotional stressors 2003 ·Neuroscience ·E.D. Schmidt,G. Aguilera,Rob Binnekade,Fred J.H. Tilders	63
2	Effects of Low-Frequency Cranial Electrostimulation on the Rest-Activity Rhythm and Salivary Cortisol in Alzheimer's Disease 2003 ·Neurorehabilitation and neural repair ·Erik Scherder,Dirk L. Knol,Eus J.W. Van Someren,J.B. Deijen,Rob Binnekade,Fred J.H. Tilders,Joseph A. Sergeant	20
3	Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells 2000 ·Pure Amsterdam UMC ·Annemarie Ledeboer,John J. P. Brevé,(unknown),Fred J.H. Tilders,(unknown)	2
4	Increased Activity of the Hypothalamic-Pituitary-Adrenal Axis of Rats Exposed to Alcohol in Utero: Role of Altered Pituitary and Hypothalamic Function 2000 ·Molecular and Cellular Neuroscience ·Soon Lee,(unknown),Fred J.H. Tilders,Catherine Rivier	69
5	IL-1β immunoreactive neurons in the human hypothalamus: reduced numbers in multiple sclerosis 2000 ·Journal of Neuroimmunology ·Inge Huitinga,(unknown),Liesbeth P. Salm,Zeynel A. Erkut,Anne‐Marie van Dam,Fred J.H. Tilders,Dick F. Swaab	47
6	Vagotomy does not inhibit high dose lipopolysaccharide-induced interleukin-1β immunoreactivity in rat brain and pituitary gland 2000 ·Neuroscience Letters ·Anne‐Marie van Dam,John G. J. M. Bol,Ron P.A. Gaykema,Lisa E. Goehler,Steven F. Maier,Linda R. Watkins,Fred J.H. Tilders	35
7	Role of astrocyte-derived tissue-type plasminogen activator in the regulation of endotoxin-stimulated nitric oxide production by microglial cells 1998 ·Pure Amsterdam UMC ·V.A.M. Vincent,Clemens W.G.M. Löwik,(unknown),A.C.W. de Bart,Fred J.H. Tilders,(unknown)	2
8	Interleukin‐1‐Induced Plasticity of Hypothalamic CRH Neurons and Long‐Term Stress Hyperresponsiveness^a 1998 ·Annals of the New York Academy of Sciences ·Fred J.H. Tilders,E.D. Schmidt	51
9	Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: A role for transforming growth factor ? 1997 ·Glia ·V.A.M. Vincent,Fred J.H. Tilders,(unknown)	115
10	CHRONIC STIMULATION OF THE HYPOTHALAMUS–PITUITARY–ADRENAL AXIS IN RATS BY INTERLEUKIN 1β: CENTRAL AND PERIPHERAL MECHANISMS 1996 ·Cytokine ·(unknown),Fred C.G.J. Sweep,Gerard J. Pesman,Fred J.H. Tilders,Ad R. Hermus	22
11	Effects of Monoclonal Antibodies to Specific Epitopes of Rat Interleukin‐1 Beta (IL‐Iβ) on IL‐1β‐Induced ACTH, Corticosterone and IL‐6 Responses in Rats 1995 ·Journal of Neuroendocrinology ·K. Schotanus,Rob H. Meloen,Wouter C. Puijk,F. Berkenbosch,Rob Binnekade,Fred J.H. Tilders	8
12	Increased Numbers of Corticotropin-Releasing Hormone Expressing Neurons in the Hypothalamic Paraventricular Nucleus of Depressed Patientsbreakdown → 1994 ·Neuroendocrinology ·F.C. Raadsheer,Witte J.G. Hoogendijk,(unknown),Fred J.H. Tilders,Dick F. Swaab	507
13	Phenotypic Plasticity of CRF Neurons during Stressa 1993 ·Annals of the New York Academy of Sciences ·Fred J.H. Tilders,E.D. Schmidt,Dimphena C.E. de Goeij	80
14	Characterization of stress-induced long-term behavioural changes in rats: Evidence in favor of anxiety 1992 ·Physiology & Behavior ·Hielke H. van Dijken,J. Mos,J.A.M. van der Heyden,Fred J.H. Tilders	140
15	Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain. 1991 ·The Journal of Experimental Medicine ·Jane K. Relton,Paul J. L. M. Strijbos,C.T. O'Shaughnessy,F. Carey,Robert A. Forder,Fred J.H. Tilders,N. J. Rothwell	120
16	Selective Depletion of Macrophages Prevents Pituitary-Adrenal Activation in Response to Subpyrogenic, but not to Pyrogenic, Doses of Bacterial Endotoxin in Rats* 1991 ·Endocrinology ·Roel H. DeRijk,Nico van Rooijen,Fred J.H. Tilders,Hugo O. Besedovsky,Adriana del Rey,F. Berkenbosch	96
17	Central activation of thermogenesis and fever by interleukin-1β and interleukin-1α involves different mechanisms 1989 ·Biochemical and Biophysical Research Communications ·(unknown),Michael J. Dascombe,Fred J.H. Tilders,(unknown),E. A. Linton,Nancy J. Rothwell	59
18	Hypoglycemia Enhances Turnover of Corticotropin-Releasing Factor and of Vasopressin in the Zona Externa of the Rat Median Eminence* 1989 ·Endocrinology ·F. Berkenbosch,Dimphena C.E. de Goeij,Fred J.H. Tilders	51
19	Quantitative immunocytochemistry of corticotropin-releasing factor (CRF). Studies on nonbiological models and on hypothalamic tissues of rats after hypophysectomy, adrenalectomy and dexamethasone treatment 1984 ·Brain Research ·J. Schipper,Taco R. Werkman,Fred J.H. Tilders	30
20	Vasopressin Is not Involved in the Catecholamine-Induced Release of ACTH, α-MSH and β-Endorphin from the Rat Pituitary Gland 1983 ·Neuroendocrinology ·F. Berkenbosch,I. Vermes,Ruud M. Buijs,Fred J.H. Tilders	6

About Fred J.H. Tilders

Fred J.H. Tilders is a scholar working on Behavioral Neuroscience, Biological Psychiatry and Endocrine and Autonomic Systems, having authored 163 papers that have together received 9.9k indexed citations. Recurring topics across this work include Stress Responses and Cortisol (90 papers), Neuroendocrine regulation and behavior (44 papers) and Neuropeptides and Animal Physiology (23 papers). The work is most often cited by research in Behavioral Neuroscience (5.2k citations), Biological Psychiatry (1.6k citations) and Endocrine and Autonomic Systems (1.6k citations). Fred J.H. Tilders has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include F. Berkenbosch, Dick F. Swaab, E.D. Schmidt, F.C. Raadsheer, Adriana del Rey, Hugo O. Besedovsky, Rob Binnekade, Dimphena C.E. de Goeij, Witte J.G. Hoogendijk and I. Vermes. Their work appears in journals such as Nature, Science and The Journal of Experimental Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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