Hugo O. Besedovsky

13.4k total citations · 4 hit papers
143 papers, 10.3k citations indexed

About

Hugo O. Besedovsky is a scholar working on Immunology, Behavioral Neuroscience and Neurology. According to data from OpenAlex, Hugo O. Besedovsky has authored 143 papers receiving a total of 10.3k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Immunology, 39 papers in Behavioral Neuroscience and 37 papers in Neurology. Recurrent topics in Hugo O. Besedovsky's work include Stress Responses and Cortisol (39 papers), Neuroinflammation and Neurodegeneration Mechanisms (28 papers) and Adrenal Hormones and Disorders (25 papers). Hugo O. Besedovsky is often cited by papers focused on Stress Responses and Cortisol (39 papers), Neuroinflammation and Neurodegeneration Mechanisms (28 papers) and Adrenal Hormones and Disorders (25 papers). Hugo O. Besedovsky collaborates with scholars based in Germany, Argentina and Switzerland. Hugo O. Besedovsky's co-authors include Adriana del Rey, E. Sorkin, Charles A. Dinarello, F. Berkenbosch, Fred J.H. Tilders, Alexa Kabiersch, C.G. Honegger, Óscar Bottasso, Ábel Lajtha and Fernando J. Pitossi and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Hugo O. Besedovsky

141 papers receiving 9.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Immune-Neuro-Endocrine Interactions: Facts and Hypotheses

1996 1.2k citations Hugo O. Besedovsky, Adriana del Rey Endocrine Reviews profile →
Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 1.2k citations Hugo O. Besedovsky, Adriana del Rey et al. profile →
Corticotropin-Releasing Factor-Producing Neurons in the Rat Activated by Interleukin-1

1987 913 citations F. Berkenbosch, Adriana del Rey et al. profile →
Immunoregulation mediated by the sympathetic nervous system

1979 380 citations Hugo O. Besedovsky, Adriana del Rey et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hugo O. Besedovsky Germany	47	3.6k	2.1k	2.0k	1.8k	1.6k	143	10.3k
Adriana del Rey Germany	47	3.4k 0.9×	2.1k 1.0×	2.2k 1.1×	1.9k 1.0×	1.5k 0.9×	146	9.8k
Fred J.H. Tilders Netherlands	55	5.2k 1.5×	1.4k 0.7×	1.6k 0.8×	1.6k 0.9×	1.5k 0.9×	163	9.9k
Adrian J. Dunn United States	56	5.0k 1.4×	752 0.4×	1.3k 0.7×	2.7k 1.5×	1.8k 1.1×	183	11.0k
Gregory G. Freund United States	38	2.6k 0.7×	1.2k 0.6×	2.0k 1.0×	3.6k 2.0×	2.1k 1.3×	121	9.9k
Monika Fleshner United States	72	5.6k 1.6×	1.0k 0.5×	2.0k 1.0×	2.4k 1.3×	3.0k 1.9×	213	16.1k
J. Edwin Blalock United States	68	2.6k 0.7×	3.5k 1.6×	690 0.4×	853 0.5×	4.7k 3.0×	303	15.5k
Raz Yirmiya Israel	57	4.8k 1.3×	1.1k 0.5×	4.1k 2.1×	5.1k 2.8×	1.8k 1.2×	149	12.7k
Ilia J. Elenkov United States	33	1.8k 0.5×	1.6k 0.8×	763 0.4×	810 0.4×	986 0.6×	39	6.9k
Rodney W. Johnson United States	62	4.1k 1.2×	2.4k 1.1×	5.5k 2.8×	5.5k 3.0×	3.0k 1.9×	205	18.2k
Carmen Guaza Spain	54	1.2k 0.3×	959 0.4×	1.3k 0.7×	1.1k 0.6×	1.8k 1.1×	160	8.5k

Countries citing papers authored by Hugo O. Besedovsky

Since Specialization

Citations

This map shows the geographic impact of Hugo O. Besedovsky's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hugo O. Besedovsky with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hugo O. Besedovsky more than expected).

Fields of papers citing papers by Hugo O. Besedovsky

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hugo O. Besedovsky. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hugo O. Besedovsky. The network helps show where Hugo O. Besedovsky may publish in the future.

Co-authorship network of co-authors of Hugo O. Besedovsky

This figure shows the co-authorship network connecting the top 25 collaborators of Hugo O. Besedovsky. A scholar is included among the top collaborators of Hugo O. Besedovsky based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hugo O. Besedovsky. Hugo O. Besedovsky is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Besedovsky, Hugo O. & Adriana del Rey. (2022). To protect or to kill: A persisting Darwinian immune dilemma. Brain Behavior and Immunity. 103. 205–214. 1 indexed citations

Besedovsky, Hugo O.. (2018). The immune system as a sensorial system that can modulate brain functions and reset homeostasis. Annals of the New York Academy of Sciences. 1437(1). 5–14. 9 indexed citations

Wolff, Christine, Rainer H. Straub, Anke Randolf, et al.. (2015). Mimicking disruption of brain-immune system-joint communication results in collagen type II-induced arthritis in non-susceptible PVG rats. Molecular and Cellular Endocrinology. 415. 56–63. 3 indexed citations

Nava‐Castro, Karen Elizabeth, Saé Muñiz‐Hernández, Romel Hernández‐Bello, et al.. (2014). Gender-Associated Differential Expression of Cytokines in Specific Areas of the Brain During Helminth Infection. Journal of Interferon & Cytokine Research. 35(2). 116–125. 9 indexed citations

Besedovsky, Hugo O. & A. Rey. (2014). Physiologic Versus Diabetogenic Effects of Interleukin-1: A Question of Weight. Current Pharmaceutical Design. 20(29). 4733–4740. 14 indexed citations

Wildmann, Johannes, et al.. (2012). T cells affect central and peripheral noradrenergic mechanisms and neurotrophin concentration in the spleen and hypothalamus. Annals of the New York Academy of Sciences. 1261(1). 18–25. 9 indexed citations

Engler, Harald, Raphaël Doenlen, Carsten Riether, et al.. (2010). Chemical destruction of brain noradrenergic neurons affects splenic cytokine production. Journal of Neuroimmunology. 219(1-2). 75–80. 16 indexed citations

Bay, María Luisa, et al.. (2010). The Immune-Endocrine-Metabolic Unit During Human Tuberculosis. Current Immunology Reviews. 6(4). 314–322. 5 indexed citations

Besedovsky, Hugo O. & Adriana del Rey. (2010). Interleukin-1 Resets Glucose Homeostasis at Central and Peripheral Levels: Relevance for Immunoregulation. NeuroImmunoModulation. 17(3). 139–141. 10 indexed citations

10.

Savino, Wilson, et al.. (2009). Neuroimmunomodulation : from fundamental biology to therapy. Annals of the New York Academy of Sciences. 1171. 1 indexed citations

11.

Pérez, Ana Rosa, et al.. (2007). Thymus atrophy during Trypanosoma cruzi infection is caused by an immuno-endocrine imbalance. Brain Behavior and Immunity. 21(7). 890–900. 84 indexed citations

12.

Besedovsky, Hugo O., Detlef Balschun, Fernando J. Pitossi, H. Schneider, & Adriana del Rey. (2004). Brain cytokines integrate immune and neural signals. Periodicum Biologorum. 106(4). 325–328. 1 indexed citations

13.

Balschun, Detlef, et al.. (2003). Hippocampal Interleukin‐1β Gene Expression during Long‐Term Potentiation Decays with Age. Annals of the New York Academy of Sciences. 992(1). 1–8. 36 indexed citations

14.

Kabiersch, Alexa, Hiromu Furukawa, Adriana del Rey, & Hugo O. Besedovsky. (1998). Administration of Interleukin‐1 at Birth Affects Dopaminergic Neurons in Adult Mice^a. Annals of the New York Academy of Sciences. 840(1). 123–127. 36 indexed citations

15.

Schneider, Hannah, Fernando J. Pitossi, Detlef Balschun, et al.. (1998). IL-1 receptor antagonist blocks the maintenance of long term potentiation in vitro and in vivo. European Cytokine Network. 9(3). 383–383. 1 indexed citations

16.

Pitossi, Fernando J., Adriana del Rey, Alexa Kabiersch, & Hugo O. Besedovsky. (1997). Induction of cytokine transcripts in the central nervous system and pituitary following peripheral administration of endotoxin to mice. Journal of Neuroscience Research. 48(4). 287–298. 155 indexed citations

17.

Besedovsky, Hugo O.. (1996). Immune-neuro-endocrine interactions: facts and hypotheses. Endocrine Reviews. 17(1). 64–102. 121 indexed citations

18.

DeRijk, Roel H., Nico van Rooijen, Fred J.H. Tilders, et al.. (1991). Selective Depletion of Macrophages Prevents Pituitary-Adrenal Activation in Response to Subpyrogenic, but not to Pyrogenic, Doses of Bacterial Endotoxin in Rats*. Endocrinology. 129(1). 330–338. 96 indexed citations

19.

Normann, Sigurd J., et al.. (1988). Interactions Between Endogenous Glucocorticoids and Inflammatory Responses in Normal and Tumor-Bearing Mice: Role of T Cells. Journal of Leukocyte Biology. 44(6). 551–558. 17 indexed citations

20.

Besedovsky, Hugo O. & Adriana del Rey. (1987). Neuroendocrine and metabolic responses induced by Interleukin‐1. Journal of Neuroscience Research. 18(1). 172–178. 66 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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