Frank Lezoualc’h

17.8k total citations · 2 hit papers
84 papers, 9.7k citations indexed

About

Frank Lezoualc’h is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Cellular and Molecular Neuroscience. According to data from OpenAlex, Frank Lezoualc’h has authored 84 papers receiving a total of 9.7k indexed citations (citations by other indexed papers that have themselves been cited), including 61 papers in Molecular Biology, 18 papers in Cardiology and Cardiovascular Medicine and 15 papers in Cellular and Molecular Neuroscience. Recurrent topics in Frank Lezoualc’h's work include Receptor Mechanisms and Signaling (24 papers), Phosphodiesterase function and regulation (22 papers) and Signaling Pathways in Disease (15 papers). Frank Lezoualc’h is often cited by papers focused on Receptor Mechanisms and Signaling (24 papers), Phosphodiesterase function and regulation (22 papers) and Signaling Pathways in Disease (15 papers). Frank Lezoualc’h collaborates with scholars based in France, United States and Netherlands. Frank Lezoualc’h's co-authors include Barbara Demeneix, Jean‐Paul Behr, Daniel Scherman, Otmane Boussif, Christian Behl, Éric Morel, Rodolphe Fischmeister, Thomas Skutella, Florian Holsboer and Anke Post and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Frank Lezoualc’h

82 papers receiving 9.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

1995 5.2k citations Frank Lezoualc’h, Barbara Demeneix et al. profile →
Neuroprotection against Oxidative Stress by Estrogens: Structure-Activity Relationship

1997 646 citations Christian Behl, Frank Lezoualc’h et al. profile →

Peers

Countries citing papers authored by Frank Lezoualc’h

Since Specialization

Citations

This map shows the geographic impact of Frank Lezoualc’h's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Lezoualc’h with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Lezoualc’h more than expected).

Fields of papers citing papers by Frank Lezoualc’h

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Lezoualc’h. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Lezoualc’h. The network helps show where Frank Lezoualc’h may publish in the future.

Co-authorship network of co-authors of Frank Lezoualc’h

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Lezoualc’h. A scholar is included among the top collaborators of Frank Lezoualc’h based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Lezoualc’h. Frank Lezoualc’h is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	EPAC1 enhances brown fat growth and beige adipogenesis 2024 ·Nature Cell Biology ·Laia Reverte-Salisa, (unknown), Staffan Hildebrand, Xi Yao, (unknown), Michelle Y. Jaeckstein, Jöerg Heeren, Frank Lezoualc’h, Natalie Krahmer, Alexander Pfeifer	23
2	Macromolecular Complex Including MLL3, Carabin and Calcineurin Regulates Cardiac Remodeling 2023 ·Circulation Research ·(unknown), (unknown), Karina Formoso, (unknown), Yannis Sainte–Marie, (unknown), (unknown), (unknown), (unknown), Émeline Lhuillier, Frank Lezoualc’h, Caroline Conte	1
3	EPAC1 Pharmacological Inhibition with AM-001 Prevents SARS-CoV-2 and Influenza A Virus Replication in Cells 2023 ·Viruses ·(unknown), (unknown), (unknown), (unknown), Alexandre Lucas, (unknown), Marine Wasniewski, Alexandre Servat, Arnaud Tessier, Frank Lezoualc’h, Romain Volmer	3
4	Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics 2020 ·Journal of Computer-Aided Molecular Design ·(unknown), Marion Laudette, Jean‐Paul Blondeau, Frank Lezoualc’h, Marianna Nalli, Romano Silvestri, Andrea Brancale, Antonio Coluccia	3
5	Mitochondrial 4-HNE derived from MAO-A promotes mitoCa2+ overload in chronic postischemic cardiac remodeling 2019 ·Cell Death and Differentiation ·Yohan Santin, Loubina Fazal, Yannis Sainte–Marie, Pierre Sicard, Damien Maggiorani, Florence Tortosa, (unknown), (unknown), Jacques Rouquette, Marlène Marcellin, Cécile Vindis, Jean C. Shih, Olivier Lairez, Odile Burlet‐Schiltz, Angelo Parini, Frank Lezoualc’h, Jeanne Mialet‐Perez	67
6	Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy 2014 ·Cardiovascular Research ·Anne‐Coline Laurent, Malik Bisserier, Alexandre Lucas, Florence Tortosa, (unknown), (unknown), Audrey Swiader, Yannis Sainte–Marie, Christophe Heymes, Cécile Vindis, Frank Lezoualc’h	61
7	The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1) 2013 ·Biochemical and Biophysical Research Communications ·Delphine Courilleau, Pascal Bouyssou, Rodolphe Fischmeister, Frank Lezoualc’h, Jean‐Paul Blondeau	56
8	Specific interactions between Epac1, β-arrestin2 and PDE4D5 regulate β-adrenergic receptor subtype differential effects on cardiac hypertrophic signaling 2012 ·Cellular Signalling ·(unknown), Alexandre Lucas, Aude Saulière, Yuan Yan Sin, Anne‐Coline Laurent, Céline Galès, George S. Baillie, Frank Lezoualc’h	50
9	PKC-delta and PKC-epsilon: Foes of the same family or strangers? 2011 ·Journal of Molecular and Cellular Cardiology ·Nicolas Duquesnes, Frank Lezoualc’h, Bertrand Crozatier	80
10	Epac enhances excitation–transcription coupling in cardiac myocytes 2011 ·Journal of Molecular and Cellular Cardiology ·Laëtitia Pereira, Gema Ruiz‐Hurtado, Éric Morel, Anne‐Coline Laurent, Mélanie Metrich, Alejandro Domínguez‐Rodríguez, Sandra Lauton‐Santos, Alexandre Lucas, Jean‐Pierre Bénitah, Donald M. Bers, Frank Lezoualc’h, Ana M. Gómez	58
11	Functional characterization of the cAMP-binding proteins Epac in cardiac myocytes 2009 ·Pharmacological Reports ·Mélanie Metrich, Éric Morel, Magali Berthouze, Laëtitia Pereira, Philippe Charron, Ana M. Gómez, Frank Lezoualc’h	19
12	Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4receptor and its consequences in early BALB/c mouse embryonic development 2007 ·BMC Developmental Biology ·Rehab Kamel, (unknown), Frank Lezoualc’h, Rodolphe Fischmeister, Sylviane Muller, (unknown), Pierre Eftekhari	11
13	The cAMP binding protein Epac modulates Ca ²⁺ sparks by a Ca ²⁺ /calmodulin kinase signalling pathway in rat cardiac myocytes 2007 ·The Journal of Physiology ·Laëtitia Pereira, Mélanie Metrich, María Fernández‐Velasco, Alexandre Lucas, Jérôme Leroy, Romain Perrier, Éric Morel, Rodolphe Fischmeister, Sylvain Richard, Jean‐Pierre Bénitah, Frank Lezoualc’h, Ana M. Gómez	173
14	VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux 2007 ·Neuropharmacology ·Eric G. Mohler, Sharon Shacham, Silvia Noiman, Frank Lezoualc’h, Sylvain J. Robert, Monique Gastineau, Joseph M. Rutkowski, Yael Marantz, Aline Dumuis, Joël Bockaert, Paul E. Gold, Michael E. Ragozzino	87
15	A high-affinity monoclonal antibody with functional activity against the 5-hydroxytryptaminergic (5-HT4) receptor 2005 ·Biochemical Pharmacology ·Rehab Kamel, Pierre Eftekhari, (unknown), Magali Berthouze, Isabelle Berque‐Bestel, Jean‐Christophe Peter, Frank Lezoualc’h, Johan Hoebeke	17
16	New Insights into Serotonin 5-HT4 Receptors : A Novel Therapeutic Target for Alzheimers Disease? 2004 ·Current Alzheimer Research ·Marjorie Maillet, Sylvain J. Robert, Frank Lezoualc’h	44
17	Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4serotoninergic receptor could explain neonatal lupus congenital heart block 2000 ·European Journal of Immunology ·Pierre Eftekhari, Laurent Sallé, Frank Lezoualc’h, Jeanne Mialet‐Perez, Monique Gastineau, Jean‐Paul Briand, David Isenberg, Gilbert J. Fournié, Jorge Argibay, Rodolphe Fischmeister, Sylviane Muller, Johan Hoebeke	95
18	Isolation of the serotoninergic 5‐HT_4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6‐glial and CHO cell lines 2000 ·British Journal of Pharmacology ·Jeanne Mialet‐Perez, Isabelle Berque‐Bestel, Pierre Eftekhari, Monique Gastineau, (unknown), (unknown), Patrick Donzeau‐Gouge, Johan Hoebeke, Michel Langlois, Sames Sicsic, Rodolphe Fischmeister, Frank Lezoualc’h	56
19	Estrogens with an Intact Phenolic Group Prevent Death of Neuronal Cells Following Glutathione Depletion 1998 ·Restorative Neurology and Neuroscience ·Christian Behl, Frank Lezoualc’h	10
20	Inhibition of Neurogenic Precursor Proliferation by Antisense α Thyroid Hormone Receptor Oligonucleotides 1995 ·Journal of Biological Chemistry ·Frank Lezoualc’h, Isabelle Seugnet, (unknown), Jacques Ghysdael, Jean‐Paul Behr, Barbara Demeneix	36

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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