Frank L. Graham

34.0k citations

184 papers · 28.6k indexed · 7 hit papers · h-index 69

Molecular Biology top 0.1%
Genetics top 0.01%
Oncology top 0.2%
Immunology top 0.5%
Epidemiology top 0.5%

Co-authors: A.J. van der Eb James R. Smiley RODERICK NAIRN W. C. Russell L. Prevec Jack Gauldie Robin J. Parks Mary Hitt
Topics: Virus-based gene therapy research (152 papers)Viral Infectious Diseases and Gene Expression in Insects (73 papers)CAR-T cell therapy research (39 papers)
Cited by: Genetics Molecular Biology Virology
Journals: Nature Cell Proceedings of the National Academy of Sciences
Partner nations: Canada United States Netherlands

In The Last Decade

Frank L. Graham

182 papers receiving 26.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 9.0k citations Frank L. Graham et al. Virology profile →
Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 4.0k citations Frank L. Graham et al. Journal of General Virology profile →
Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

1997 836 citations Frank L. Graham, Jack Gauldie et al. Journal of Clinical Investigation profile →
Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells

2002 625 citations Frank L. Graham et al. profile →
Transformation of rat cells by DNA of human adenovirus 5

1973 589 citations Frank L. Graham et al. Virology profile →
A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal

1996 569 citations Robin J. Parks, Martina Anton et al. profile →
A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

1988 553 citations Frank L. Graham et al. Virology profile →

Peers

Countries citing papers authored by Frank L. Graham

Since Specialization

Citations

This map shows the geographic impact of Frank L. Graham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank L. Graham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank L. Graham more than expected).

Fields of papers citing papers by Frank L. Graham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank L. Graham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank L. Graham. The network helps show where Frank L. Graham may publish in the future.

Co-authorship network of co-authors of Frank L. Graham

This figure shows the co-authorship network connecting the top 25 collaborators of Frank L. Graham. A scholar is included among the top collaborators of Frank L. Graham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank L. Graham. Frank L. Graham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	A phase I trial of adenovector-mediated delivery of interleukin-2 (AdIL-2) in high-risk localized prostate cancer 2003 ·Cancer Gene Therapy ·(unknown),John Trachtenberg,Ants Toi,Joan Sweet,Zhihua Li,Michael Jewett,(unknown),(unknown),Mary Hitt,Yonghong Wan,Jack Gauldie,Frank L. Graham,Janet Dancey,A. Keith Stewart	47
2	Large Nontransplanted Hepatocellular Carcinoma in Woodchucks: Treatment With Adenovirus-Mediated Delivery of Interleukin 12/B7.1 Genes 2001 ·JNCI Journal of the National Cancer Institute ·Brigitte M. Pützer,Thorsten Stiewe,(unknown),Oliver Schildgen,(unknown),Olaf Dirsch,Melanie Fiedler,(unknown),Bud C. Tennant,Clemens Scherer,Frank L. Graham,M Roggendorf	48
3	Adenovirus vectors for high-efficiency gene transfer into mammalian cells 2000 ·Immunology Today ·Frank L. Graham	33
4	4 Structure and Genetic Organization of Adenovirus Vectors 1999 ·Cold Spring Harbor Monograph Archive ·Mary Hitt,Robin J. Parks,Frank L. Graham	23
5	Autologous lymphocyte responses to adenovirus-B7-1-transduced human cancer cells 1999 ·Cancer Gene Therapy ·Sophie Dessureault,Frank L. Graham,Steven Gallinger	7
6	Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models 1999 ·Human Gene Therapy ·Peter Emtage,Yonghong Wan,Mary Hitt,Frank L. Graham,William J. Muller,Albert Zlotnik,Jack Gauldie	97
7	Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis 1998 ·Molecular and Cellular Biology ·Marc Webster,John N. Hutchinson,Michael J. Rauh,Senthil K. Muthuswamy,Martina Anton,(unknown),Robert D. Cardiff,Frank L. Graham,John A. Hassell,William J. Muller	174
8	Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer 1998 ·Human Gene Therapy ·Brigitte M. Pützer,Jonathan L. Bramson,Christina Addison,Mary Hitt,Peter M. Siegel,William J. Muller,Frank L. Graham	53
9	Human Adenovirus Vectors for Gene Transfer into Mammalian Cells 1997 ·Advances in pharmacology ·Mary Hitt,Christina Addison,Frank L. Graham	156
10	Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line 1997 ·Virology ·(unknown),Carole Evelegh,Frank L. Graham	170
11	Construction, function and in vivo expression of a complement receptor type 1 containing recombinant adenovirus for use in xenotransplantation 1997 ·Transplantation Proceedings ·(unknown),(unknown),Junko Nakamura,Joy Hammel,D T Fearon,Frank L. Graham,Ira J. Fox	1
12	B7-1 gene transfer into human cancer cells by infection with an adenovirus-B7 (Ad-B7) expression vector 1996 ·Annals of Surgical Oncology ·Sophie Dessureault,Frank L. Graham,Steven Gallinger	8
13	Investigation of promoter function in human and animal cells infected with human recombinant adenoviruses expressing rotavirus antigen VP7sc 1995 ·Journal of General Virology ·(unknown),Valeri Krougliak,L. Prevec,Frank L. Graham,G W Both	21
14	Identification of Adenovirus E1A Regions Which Affect MHC Class I Expression and Susceptibility to Cytotoxic T Lymphocytes 1995 ·Virology ·Daniel S. Pereira,(unknown),Frank L. Graham	22
15	Herpes Simplex Virus (HSV) Glycoproteins B and K Inhibit Cell Fusion Induced by HSV Syncytial Mutants 1993 ·Virology ·Lloyd Hutchinson,Frank L. Graham,Weizhong Cai,Chitrita DebRoy,Stanley Person,David C. Johnson	36
16	Monitoring foreign gene expression by a human adenovirus-based vector using the firefly luciferase gene as a reporter 1993 ·Virus Research ·Suresh K. Mittal,Mark R. McDermott,David C. Johnson,L. Prevec,Frank L. Graham	121
17	Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes. 1993 ·Journal of Clinical Investigation ·(unknown),(unknown),Andrew Bett,Frank L. Graham,C. Thomas Caskey	78
18	Transduction of the CHOaprt gene into mouse L cells using an adeno-5/APRT recombinant virus 1991 ·Somatic Cell and Molecular Genetics ·(unknown),Amrik Sahota,Frank L. Graham,Michael W. Taylor	4
19	Cytotoxic T lymphocytes specific for herpes simplex virus (HSV) studied using adenovirus vectors expressing HSV glycoproteins 1990 ·Journal of General Virology ·(unknown),K L Rosenthal,Frank L. Graham,(unknown),Anne Yee,David C. Johnson	45
20	The effect of E1 mutations on biochemical transformation by an adenovirus carrying the herpes simplex virus thymidine kinase gene in region E3 1989 ·Virus Research ·Gary M. Wilson,Frank L. Graham	1

About Frank L. Graham

Frank L. Graham is a scholar working on Genetics, Infectious Diseases and Oncology, having authored 184 papers that have together received 28.6k indexed citations. Recurring topics across this work include Virus-based gene therapy research (152 papers), Viral Infectious Diseases and Gene Expression in Insects (73 papers) and CAR-T cell therapy research (39 papers). The work is most often cited by research in Genetics (14.3k citations), Molecular Biology (17.7k citations) and Virology (1.2k citations). Frank L. Graham has collaborated with scholars based in Canada, United States and Netherlands. Frequent co-authors include A.J. van der Eb, James R. Smiley, RODERICK NAIRN, W. C. Russell, L. Prevec, Jack Gauldie, Robin J. Parks, Mary Hitt, G. F. Whitmore and Martina Anton. Their work appears in journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact