Frank J. Beurskens

5.8k citations

72 papers · 4.4k indexed · 2 hit papers · h-index 32

Immunology top 0.5%
- Complement system in diseases 29
- T-cell and B-cell Immunology 9
- Immune Cell Function and Interaction 8
Virology top 1%
Radiology, Nuclear Medicine and Imaging top 0.5%
- Monoclonal and Polyclonal Antibodies Research 51
Genetics top 2%
- Chronic Lymphocytic Leukemia Research 14
Hematology top 2%
- Blood groups and transfusion 13
Molecular Biology
- Glycosylation and Glycoproteins Research 17
Microbiology
- Bacterial Infections and Vaccines 5

Co-authors: Paul W.H.I. Parren Janine Schuurman Jan G. J. van de Winkel Ronald P. Taylor Margaret A. Lindorfer Rob N. de Jong Dennis R. Burton Joost M. Bakker
Cited by: Immunology Virology Radiology, Nuclear Medicine and Imaging
Journals: The Journal of Immunology (11 papers)Molecular Immunology (8 papers)Blood (4 papers)
Partner nations: Netherlands United States Denmark

In The Last Decade

Frank J. Beurskens

71 papers receiving 4.3k citations

Hit Papers

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Peers

Countries citing papers authored by Frank J. Beurskens

Since Specialization

Citations

This map shows the geographic impact of Frank J. Beurskens's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank J. Beurskens with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank J. Beurskens more than expected).

Fields of papers citing papers by Frank J. Beurskens

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank J. Beurskens. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank J. Beurskens. The network helps show where Frank J. Beurskens may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Frank J. Beurskens, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frank J. Beurskens Line = papers co-authored together Frank J. Beurskens links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Complement activation by IgG subclasses is governed by their ability to oligomerize upon antigen binding Proceedings of the National Academy of Sciences ·J. F. Barreto,Jürgen Strasser,Ellen G. F. Borg,Aran F. Labrijn,Frank J. Beurskens,Johannes Preiner	2024	7
2	Agnostic B cell selection approach identifies antibodies against K. pneumoniae that synergistically drive complement activation Nature Communications ·T Smithers,Bart W. Bardoel,Maartje Ruyken,Carla J. C. de Haas,Hossein Shiri,赵雪珂,María Julia López García,Piet C. Aerts,Yuli Ardiani,Johannes Preiner,Renoud J. Marijnissen,Janine Schuurman,Frank J. Beurskens,Priscilla F. Kerkman,Suzan H. M. Rooijakkers	2024	6
3	Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches Seminars in Immunology ·Vitalijs Ovcinnikovs,Karin Dijkman,Gijs G. Zom,Frank J. Beurskens,Leendert A. Trouw	2024	10
4	Monoclonal antibodies effectively potentiate complement activation and phagocytosis of Staphylococcus epidermidis in neonatal human plasma Frontiers in Immunology ·王春庭,Rafael Herrera,Ahmed S. Abou-Elyazed,María Julia López García,Piet C. Aerts,Daniel C. Vijlbrief,Mireille N. Bekker,Frank J. Beurskens,Kok P. M. van Kessel,Carla J. C. de Haas,Suzan H. M. Rooijakkers,Michiel van der Flier	2022	7
5	Biophysical Characterization and Stability of Modified IgG1 Antibodies with Different Hexamerization Propensities Journal of Pharmaceutical Sciences ·Muriel D. van Kampen,Le Galand-Carval,Rory W. Steinke,L V Budakova,Ewald T.J. van den Bremer,Guanbo Wang,Albert J. R. Heck,Paul W.H.I. Parren,Frank J. Beurskens,Janine Schuurman,Rob N. de Jong	2022	10
6	C1q binding to surface-bound IgG is stabilized by C1r ₂ s ₂ proteases Proceedings of the National Academy of Sciences ·Xiaohong Kuang,Mona Pia Glock,Annemarie Kuipers,Jürgen Strasser,Maartje Ruyken,Piet C. Aerts,Carla J. C. de Haas,Deniz Ugurlar,Maurits A. den Boer,Gestur Vidarsson,Jos A. G. van Strijp,Piet Gros,Paul W.H.I. Parren,Kok P. M. van Kessel,Johannes Preiner,Frank J. Beurskens,Janine Schuurman,Daniel Ricklin,Suzan H. M. Rooijakkers	2021	39
7	Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation Proceedings of the National Academy of Sciences ·Ana Rita Cruz,Maurits A. den Boer,Jürgen Strasser,Xiaohong Kuang,Frank J. Beurskens,Carla J. C. de Haas,Piet C. Aerts,Guanbo Wang,Rob N. de Jong,Fábio Bagnoli,Jos A. G. van Strijp,Kok P. M. van Kessel,Janine Schuurman,Johannes Preiner,Albert J. R. Heck,Suzan H. M. Rooijakkers	2021	67
8	Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism Molecular Cancer Therapeutics ·Marije B. Overdijk,Kristin Strumane,Frank J. Beurskens,Antonio Ortiz Buijsse,Claudine Vermot‐Desroches,Hilyana Zilfit,Thessa Kroes,服部政治,Т.А. Дятлова,Richard G. Hibbert,Andreas Lingnau,Ulf Forssmann,Janine Schuurman,Paul W.H.I. Parren,Rob N. de Jong,Esther C.W. Breij	2020	36
9	Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody PLoS Biology ·Sunita Gulati,Frank J. Beurskens,Bart-Jan de Kreuk,Marcel Roza,Bo Zheng,Rosane B. DeOliveira,Jutamas Shaughnessy,Nancy Nowak,Ronald P. Taylor,Marina Botto,Xianbao He,Robin R. Ingalls,Trent M. Woodruff,Wen‐Chao Song,Janine Schuurman,Peter A. Rice,Sanjay Ram	2019	62
10	Immune Effector Functions of Human IgG2 Antibodies against EGFR Molecular Cancer Therapeutics ·Thies Rösner,A Lateng,Uva A. Clavijo,Hanke L. Matlung,J.H. Marco Jansen,Mitchell Evers,Frank J. Beurskens,Jeanette H.W. Leusen,Timo K. van den Berg,Thomas Valerius	2018	25
11	Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells The Journal of Immunology ·Jonghyun Sohn,Stefanie Derer,Ralf Schwanbeck,Thies Rösner,J.H. Westing,Frank J. Beurskens,Janine Schuurman,Paul W.H.I. Parren,Thomas Valerius	2017	23
12	Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions The Journal of Immunology ·Erika M. Cook,Margaret A. Lindorfer,钱春荣,Simone C. Oostindie,Frank J. Beurskens,Janine Schuurman,Clive S. Zent,Richard Burack,Paul W.H.I. Parren,Ronald P. Taylor	2016	48
13	A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface PLoS Biology ·Rob N. de Jong,Frank J. Beurskens,Sandra Verploegen,Kristin Strumane,Muriel D. van Kampen,Marleen Voorhorst,علی کاظميان,Patrick Engelberts,Simone C. Oostindie,Guanbo Wang,Albert J. R. Heck,Janine Schuurman,Paul W.H.I. Parren	2016	153
14	The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden Haematologica ·Péter Boross,J.H. Marco Jansen,Simone de Haij,Frank J. Beurskens,Cees E. van der Poel,Lisette Bevaart,Maaike Nederend,Josée Golay,Jan G. J. van de Winkel,Paul W.H.I. Parren,Jeanette H.W. Leusen	2011	55
15	Binding of Submaximal C1q Promotes Complement-Dependent Cytotoxicity (CDC) of B Cells Opsonized with Anti-CD20 mAbs Ofatumumab (OFA) or Rituximab (RTX): Considerably Higher Levels of CDC Are Induced by OFA than by RTX The Journal of Immunology ·Andrew W. Pawluczkowycz,Frank J. Beurskens,Paul V. Beum,Margaret A. Lindorfer,Jan G. J. van de Winkel,Paul W.H.I. Parren,Ronald P. Taylor	2009	198
16	IL-8 as Antibody Therapeutic Target in Inflammatory Diseases: Reduction of Clinical Activity in Palmoplantar Pustulosis The Journal of Immunology ·Lone Skov,Frank J. Beurskens,Claus Zachariae,Sakari Reitamo,Jessica L. Teeling,David Satijn,Kim Knudsen,Colin Lanceley,Darryl Hudson,Ole Baadsgaard,Paul W.H.I. Parren,Jan G. J. van de Winkel	2008	134
17	Complement Activation on B Lymphocytes Opsonized with Rituximab or Ofatumumab Produces Substantial Changes in Membrane Structure Preceding Cell Lysis The Journal of Immunology ·Paul V. Beum,Margaret A. Lindorfer,Frank J. Beurskens,P. Todd Stukenberg,Henk M. Lokhorst,Andrew W. Pawluczkowycz,Paul W.H.I. Parren,Jan G. J. van de Winkel,Ronald P. Taylor	2008	96
18	Manifestations of Inflammatory Arthritis Are Critically Dependent on LFA-1 The Journal of Immunology ·Gerald F. Watts,Frank J. Beurskens,Inés Martín-Padura,Christie M. Ballantyne,Lloyd B. Klickstein,Michael B. Brenner,David M. Lee	2005	67
19	Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model Journal of Clinical Investigation ·Louise S. Villadsen,Janine Schuurman,Frank J. Beurskens,Tomas Norman Dam,Frederik Dagnæs‐Hansen,Lone Skov,Jørgen Rygaard,Marleen M. Voorhorst‐Ogink,Arnout F. Gerritsen,Marc A. van Dijk,Paul W.H.I. Parren,Ole Baadsgaard,Jan G. J. van de Winkel	2003	138
20	Mouse complement components C4 and Slp act synergistically in a homologous hemolytic C4 assay European Journal of Immunology ·Frank J. Beurskens,Mario Tosi,Jean-François Guillemolles,Diane M. Robins,Michael C. Carroll,Johannes van Dijk	2000	6

About Frank J. Beurskens

Frank J. Beurskens is a scholar working on Radiology, Nuclear Medicine and Imaging, Immunology and Hematology, having authored 72 papers that have together received 4.4k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (51 papers), Complement system in diseases (29 papers), Glycosylation and Glycoproteins Research (17 papers), Chronic Lymphocytic Leukemia Research (14 papers), Blood groups and transfusion (13 papers), T-cell and B-cell Immunology (9 papers), Immune Cell Function and Interaction (8 papers) and Bacterial Infections and Vaccines (5 papers). The work is most often cited by research in Immunology (2.7k citations), Virology (494 citations) and Radiology, Nuclear Medicine and Imaging (1.8k citations). Frank J. Beurskens has collaborated with scholars based in Netherlands, United States and Denmark. Frequent co-authors include Paul W.H.I. Parren, Janine Schuurman, Jan G. J. van de Winkel, Ronald P. Taylor, Margaret A. Lindorfer, Rob N. de Jong, Dennis R. Burton, Joost M. Bakker, Albert J. R. Heck and Kristin Strumane. Their work appears in journals such as The Journal of Immunology, Molecular Immunology, Blood, Haematologica and Clinical & Experimental Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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