Fernando Setién

9.9k citations

57 papers · 3.4k indexed · 1 hit paper · h-index 30

Impact in

Cancer Research top 1%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
Molecular Biology top 2%
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Cancer-related gene regulation
- Histone Deacetylase Inhibitors Research
- Circular RNAs in diseases
- RNA Research and Splicing

Papers in ⓘ

Immunology 14
- Immune Cell Function and Interaction 7
- T-cell and B-cell Immunology 6
Molecular Biology 43
- Epigenetics and DNA Methylation 19
- RNA modifications and cancer 12
- Cancer-related gene regulation 11
- DNA Repair Mechanisms 6
- Genomics and Chromatin Dynamics 5

Co-authors: Manel Esteller (39 shared papers)Mario F. Fraga (13 shared papers)Santiago Ropero (12 shared papers)Esteban Ballestar (8 shared papers)Miguel Alaminos (9 shared papers)Montse Sánchez‐Céspedes (4 shared papers)Alberto Villanueva (11 shared papers)Celia Cerrato (1 shared paper)
Journals: Nucleic Acids Research (5 papers)Cancer Research (5 papers)Oncogene (5 papers)Proceedings of the National Academy of Sciences (4 papers)Immunogenetics (3 papers)
Partner nations: Spain United States Netherlands

In The Last Decade

Fernando Setién

57 papers receiving 3.4k citations

Hit Papers

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Genetic Unmasking of an Epigenetically Silenced microRNA in Human Cancer Cells 2007 · 729 citations

Peers

Countries citing papers authored by Fernando Setién

Since Specialization

Citations

This map shows the geographic impact of Fernando Setién's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fernando Setién with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fernando Setién more than expected).

Fields of papers citing papers by Fernando Setién

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fernando Setién. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fernando Setién. The network helps show where Fernando Setién may publish in the future.

Co-authors

The 25 scholars most cited alongside Fernando Setién, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Fernando Setién Line = papers co-authored together Fernando Setién links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 57 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Genetic Unmasking of an Epigenetically Silenced microRNA in Human Cancer Cells Cancer Research ·Amaia Lujambio, Santiago Ropero, Esteban Ballestar, Mario F. Fraga, Celia Cerrato, Fernando Setién, Sara Casado, Ana Suárez‐Gauthier, Montse Sánchez‐Céspedes, Anna Gitt, Inmaculada Spiteri, Partha Pratim Das, Carlos Caldas, Eric A. Miska, Manel Esteller Hit paper breakdown →	2007	729
2	HLA‐B27 subtypes in Asian patients with ankylosing spondylitis Evidence for new associations Tissue Antigens ·Carlos López‐Larrea, K Sujirachato, Narinder K. Mehra, P Chiewsilp, D. Isarangkura, Uma Kanga, Orlando Domı́nguez, Eliécer Coto, (unknown), Fernando Setién, Severino González-Roces	1995	208
3	A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition Nature Genetics ·Santiago Ropero, Mario F. Fraga, Esteban Ballestar, Richard C. Hamelin, Hiroyuki Yamamoto, Manuel Boix-Chornet, Rosalía Caballero, Miguel Alaminos, Fernando Setién, Maria F. Paz, Michel Herranz, José Palacios, Diego Arango, Torben F. Ørntoft, Lauri A. Aaltonen, Simó Schwartz, Manel Esteller	2006	206
4	Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing Proceedings of the National Academy of Sciences ·Sónia A. Melo, Alberto Villanueva, Cátia Moutinho, Verónica Dávalos, Riccardo Spizzo, Cristina Ivan, Simona Rossi, Fernando Setién, Oriol Casanovas, Laia Simó‐Riudalbas, F. Javier Carmona, Jordi Carrère, August Vidal, Àlvaro Aytés, Sara Puertas, Santiago Ropero, Raghu Kalluri, Carlo M. Croce, George A. Calin, Manel Esteller	2011	194
5	Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer Proceedings of the National Academy of Sciences ·Rubén Agrelo, Wen‐Hsing Cheng, Fernando Setién, Santiago Ropero, Jesús Espada, Mario F. Fraga, Michel Herranz, Maria F. Paz, Montse Sánchez‐Céspedes, María J. Artiga, David Guerrero, Antoni Castells, Cayetano von Kobbe, Vilhelm A. Bohr, Manel Esteller	2006	188
6	Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma Proceedings of the National Academy of Sciences ·María Berdasco, Santiago Ropero, Fernando Setién, Mario F. Fraga, Pablo Lapunzina, Régine Losson, Miguel Alaminos, Nai‐Kong V. Cheung, Nazneen Rahman, Manel Esteller	2009	160
7	Epigenetic Inactivation of the Circadian Clock Gene BMAL1 in Hematologic Malignancies Cancer Research ·Hiroaki Taniguchi, Agustín F. Fernández, Fernando Setién, Santiago Ropero, Esteban Ballestar, Alberto Villanueva, Hiroyuki Yamamoto, Kohzoh Imai, Yasuhisa Shinomura, Manel Esteller	2009	146
8	EMP3, a Myelin-Related Gene Located in the Critical 19q13.3 Region, Is Epigenetically Silenced and Exhibits Features of a Candidate Tumor Suppressor in Glioma and Neuroblastoma Cancer Research ·Miguel Alaminos, Verónica Dávalos, Santiago Ropero, Fernando Setién, Maria F. Paz, Michel Herranz, Mario F. Fraga, Jaume Mora, Nai‐Kong V. Cheung, William L. Gerald, Manel Esteller	2005	119
9	Inactivation of the Lamin A/C Gene by CpG Island Promoter Hypermethylation in Hematologic Malignancies, and Its Association With Poor Survival in Nodal Diffuse Large B-Cell Lymphoma Journal of Clinical Oncology ·Rubén Agrelo, Fernando Setién, Jesús Espada, María J. Artiga, María E. Rodríguez, Alberto Pérez‐Rosado, Abel Sánchez‐Aguilera, Mario F. Fraga, Miguel Á. Piris, Manel Esteller	2005	111
10	A Profile of Methyl-CpG Binding Domain Protein Occupancy of Hypermethylated Promoter CpG Islands of Tumor Suppressor Genes in Human Cancer Cancer Research ·Lidia Lopez‐Serra, Esteban Ballestar, Mario F. Fraga, Miguel Alaminos, Fernando Setién, Manel Esteller	2006	102
11	Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis Oncogene ·Carmen M. Anadon, Sònia Guil, Laia Simó‐Riudalbas, Cátia Moutinho, Fernando Setién, Anna Martínez‐Cardús, Sebastián Morán, Alberto Villanueva, Mónica Calaf, August Vidal, Pedro A. Lazo, Ilse Zondervan, Suvi Savola, Tomoko Kohno, Jun Yokota, L Ribas de Pouplana, Manel Esteller	2015	95
12	CpG island promoter hypermethylation of the pro-apoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme Carcinogenesis ·Ramón Martínez, Fernando Setién, Christiane Voelter, Sara Casado, María Paz Quesada, Gabriele Schackert, Manel Esteller	2007	78
13	Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19 Frontiers in Immunology ·Xavier Solanich, Gardenia Vargas‐Parra, Caspar I. van der Made, Annet Simons, Janneke Schuurs-Hoeijmakers, Arnau Antolí, Jesús Del Valle, Gemma Rocamora-Blanch, Fernando Setién, Manel Esteller, Simon V. van Reijmersdal, Antoni Riera‐Mestre, Joan Sabater‐Riera, Gabriel Capellá, Frank L. van de Veerdonk, Ben van der Hoven, Xavier Corbella, Alexander Hoischen, Conxi Lázaro	2021	74
14	The tumour suppressor and chromatin‐remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer EMBO Molecular Medicine ·Octavio A. Romero, Fernando Setién, Sam John, Pol Giménez‐Xavier, Gonzalo Goméz-López, David G. Pisano, Enric Condom, Alberto Villanueva, Gordon L. Hager, Montse Sánchez‐Céspedes	2012	70
15	Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context Nucleic Acids Research ·Jesús Espada, Héctor Peinado, L. Lopez-Serra, Fernando Setién, Paula López-Serra, Anna Portela, Jaime Renart, Elisa Carrasco, María I. Calvo-Sánchez, Ángeles Juarranz, Amparo Cano, Manel Esteller	2011	68
16	Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells Human Molecular Genetics ·Santiago Ropero, Fernando Setién, Jesús Espada, Mario F. Fraga, Michel Herranz, Julia Asp, Maria Serena Benassi, Alessandro Franchi, Ana Patiño‐García, Laura Sterian Ward, Judith V.M.G. Bovée, Juan C. Cigudosa, Wim Wuyts, Manel Esteller	2004	66
17	The impact of MECP2 mutations in the expression patterns of Rett syndrome patients Human Genetics ·Esteban Ballestar, Santiago Ropero, Miguel Alaminos, Judith Armstrong, Fernando Setién, Rubén Agrelo, Mario F. Fraga, Michel Herranz, Sonia Avila, Mercédes Pineda, Eugènia Monrós, Manel Esteller	2004	57
18	Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer Breast Cancer Research ·Sònia Palomeras, Ángel Díaz‐Lagares, Gemma Viñas, Fernando Setién, Humberto J. Ferreira, Glòria Oliveras, Ana B. Crujeiras, A. Hernández, David H. Lum, Alana L. Welm, Manel Esteller, Teresa Puig	2019	50
19	Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer Oncogene ·Laia Piqué, Alexia Martínez de Paz, David Piñeyro, Anna Martínez‐Cardús, Manuel Castro de Moura, Pere Llinàs‐Arias, Fernando Setién, Jorge Gómez‐Miragaya, Eva González‐Suárez, Stefán Sigurðsson, Jón G. Jónasson, Alberto Villanueva, August Vidal, Verónica Dávalos, Manel Esteller	2019	49
20	Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins Oncogene ·Lidia Lopez‐Serra, Esteban Ballestar, Santiago Ropero, Fernando Setién, L-M Billard, Mario F. Fraga, Pilar López‐Nieva, Miguel Alaminos, Dharma Carfantan Guerrero, R. Dante, Manel Esteller	2008	47

About Fernando Setién

Fernando Setién is a scholar working on Immunology, Molecular Biology, Cancer Research, Transplantation and Microbiology, having authored 57 papers that have together received 3.4k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (19 papers), RNA modifications and cancer (12 papers), Cancer-related gene regulation (11 papers), Immune Cell Function and Interaction (7 papers), T-cell and B-cell Immunology (6 papers), DNA Repair Mechanisms (6 papers), Genomics and Chromatin Dynamics (5 papers) and Genetics and Neurodevelopmental Disorders (5 papers). The work is most often cited by research in Cancer Research (1.1k citations), Molecular Biology (2.7k citations), Aging (44 citations), Immunology (403 citations) and Endocrine and Autonomic Systems (125 citations). Fernando Setién has collaborated with scholars based in Spain, United States and Netherlands. Frequent co-authors include Manel Esteller, Mario F. Fraga, Santiago Ropero, Esteban Ballestar, Miguel Alaminos, Montse Sánchez‐Céspedes, Alberto Villanueva, Celia Cerrato, Ana Suárez‐Gauthier and Inmaculada Spiteri. Their work appears in journals such as Nucleic Acids Research, Cancer Research, Oncogene, Proceedings of the National Academy of Sciences and Immunogenetics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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