F. Anthony Lai

13.2k citations

191 papers · 10.7k indexed · 3 hit papers · h-index 56

Impact in

Reproductive Medicine top 0.1%
- Sperm and Testicular Function
- Ovarian function and disorders
Physiology top 0.1%
- Calcium signaling and nucleotide metabolism

Papers in

Reproductive Medicine 49
- Sperm and Testicular Function 49
- Ovarian function and disorders 34
Physiology 22
- Calcium signaling and nucleotide metabolism 19

Co-authors: Karl Swann Gerhard Meissner Christopher M. Saunders Lynda Blayney John Parrington Michail Nomikos Mark G. Larman Éric Rousseau
Journals: Biochemical Journal (19 papers)Journal of Biological Chemistry (15 papers)Biophysical Journal (9 papers)Journal of Cell Science (9 papers)Molecular Human Reproduction (7 papers)
Partner nations: United Kingdom United States Greece

In The Last Decade

F. Anthony Lai

187 papers receiving 10.6k citations

Hit Papers

align trajectories log scale

PLCζ: a sperm-specific trigger of Ca2+ oscillations in eggs and embryo development 2002 · 804 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2002 Development
1990 Journal of Biological Chemistry
1988 Nature

Peers

Countries citing papers authored by F. Anthony Lai

Since Specialization

Citations

This map shows the geographic impact of F. Anthony Lai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by F. Anthony Lai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites F. Anthony Lai more than expected).

Fields of papers citing papers by F. Anthony Lai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by F. Anthony Lai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by F. Anthony Lai. The network helps show where F. Anthony Lai may publish in the future.

Co-authors

The 25 scholars most cited alongside F. Anthony Lai, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with F. Anthony Lai Line = papers co-authored together F. Anthony Lai links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function Cardiovascular Research ·Michèle Aumont, Avninder Dhaliwal, Махфуза Oчиловна Одилова, Dimitris Parthimos, Mark L. Bannister, N. Lowri Thomas, Muflihah Fithriani, F. Anthony Lai, Spyros Zissimopoulos	2020	8
2	Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update Frontiers in Cell and Developmental Biology ·Alaaeldin Saleh, Junaid Kashir, Angelos Thanassoulas, Bared Safieh‐Garabedian, F. Anthony Lai, Michail Nomikos	2020	48
3	Association of cardiac myosin-binding protein-C with the ryanodine receptor channel – putative retrograde regulation? Journal of Cell Science ·Sandra Valéria Araújo Macedo, Michèle Aumont, Judith White, Cédric Viéro, Christopher H. George, Spyros Zissimopoulos, F. Anthony Lai	2018	10
4	Ryanodine receptors are part of the myospryn complex in cardiac muscle Scientific Reports ·Matthew A. Benson, Caroline L. Tinsley, Adrian J. Waite, 村田洋三, Steve M. M. Sweet, Elisabeth Ehler, Christopher H. George, F. Anthony Lai, Enca Martin‐Rendon, Derek J. Blake	2017	23
5	Genetic and Biochemical Approaches for <em>In Vivo</em> and <em>In Vitro</em> Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study Journal of Visualized Experiments ·Sandra Valéria Araújo Macedo, F. Anthony Lai, Spyros Zissimopoulos	2016	3
6	Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2) Journal of Biological Chemistry ·Michail Nomikos, Jessica R. Sanders, Dimitris Parthimos, Brianna L. Scotland, Brian L. Calver, St. Bartholomew-the-Great, Adrian Smith, Mauro Passamonti, Zili Sideratou, Karl Swann, F. Anthony Lai	2015	32
7	Oligomerisation of the Human Cardiac Ryanodine Receptor Amino-Terminus Biophysical Journal ·Michèle Aumont, F. Anthony Lai, Spyros Zissimopoulos	2012	1
8	The dynamics of PKC‐induced phosphorylation triggered by Ca²⁺ oscillations in mouse eggs Journal of Cellular Physiology ·Baptiste Nairaud, Zoltán Macháty, F. Anthony Lai, Karl Swann	2012	16
9	PLCζ causes Ca ²⁺ oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P ₂ Molecular Biology of the Cell ·Yuansong Yu, Michail Nomikos, Maria Theodoridou, George Nounesis, F. Anthony Lai, Karl Swann	2011	74
10	Ouabain is a Pharmacomimic of Mutant RyR2 Ca2+ Release Dysfunction but is not a Serum-Borne Trigger of CPVT Biophysical Journal ·Huiling Zhao, Nicole Silvester, Mary O’Shea, A. Tylikowski, Raffaella Bloise, Mark C. Bagley, Valerie B. O’Donnell, Carlo Napolitano, Silvia G. Priori, F. Anthony Lai, Christopher H. George	2011	1
11	Distinct Properties of CPVT Mutations Located in the Central Domain of Human RyR2 Biophysical Journal ·Lynda Blayney, Michail Nomikos, Konrad Beck, Clementine Z. Aster, Genshi Minamida, Sreedhar Rao Boyenpally, F. Anthony Lai	2010	1
12	Redistribution of mitochondria leads to bursts of ATP production during spontaneous mouse oocyte maturation Journal of Cellular Physiology ·Yuansong Yu, Rémi Dumollard, Andreas Rossbach, F. Anthony Lai, Karl Swann	2010	201
13	Investigating the Ca2+-Cycling Basis of Rhythmicity and Synchronicity in Coupled Cardiomyocyte Monolayers Biophysical Journal ·Nicole Silvester, Huiling Zhao, Phillip M. Ashton, 謙二郎岡村, Alina R. Islamova, Shahrzad Jozghasemi, Soumen Chowdhury, F. Anthony Lai, Christopher H. George	2009	1
14	Molecular biology of ryanodine receptors Cronfa (Swansea University) ·Christopher H. George, F. Anthony Lai	2007	2
15	Syntillas Release Ca2+ at a Site Different from the Microdomain Where Exocytosis Occurs in Mouse Chromaffin Cells Biophysical Journal ·Пушкина Оксана Владимировна, Suharyani, Vincenzo Sorrentino, F. Anthony Lai, Richard A. Tuft, Lawrence M. Lifshitz, José R. Lémos, Corey L. Smith, Kevin E. Fogarty, John V. Walsh	2005	29
16	Ryanodine Receptor Regulation by Intramolecular Interaction between Cytoplasmic and Transmembrane Domains Molecular Biology of the Cell ·Christopher H. George, شیماء امین, N. Lowri Thomas, Diaa Alsultani, Nicola Walters, Alan J. Williams, F. Anthony Lai	2004	55
17	Ryanodine Receptor Oligomeric Interaction Journal of Biological Chemistry ·Lynda Blayney, Spyros Zissimopoulos, Albert D. Trevino, Vinodhini Jayapal, Paul E. Bégin, F. Anthony Lai	2004	8
18	Sperm phospholipase Czeta from humans and cynomolgus monkeys triggers Ca2+ oscillations, activation and development of mouse oocytes Reproduction ·С. А. Шерстюк, Mark G. Larman, Christopher M. Saunders, Keiko Hashimoto, Karl Swann, F. Anthony Lai	2002	231
19	Multiple isoforms of the ryanodine receptor are expressed in rat pancreatic acinar cells Biochemical Journal ·Thiago Coelho da Fonseca, Ilya Gukovsky, James A. McRoberts, Edwin S. Millis, F. Anthony Lai, Stephen J. Pandol	2000	49
20	7 A Novel Protein for Ca2+ Signaling at Fertilization Current topics in developmental biology ·John Parrington, F. Anthony Lai, Karl Swann	1998	20

About F. Anthony Lai

F. Anthony Lai is a scholar working on Reproductive Medicine, Physiology, Cardiology and Cardiovascular Medicine, Sensory Systems and Public Health, Environmental and Occupational Health, having authored 191 papers that have together received 10.7k indexed citations. Recurring topics across this work include Ion channel regulation and function (97 papers), Cardiac electrophysiology and arrhythmias (70 papers), Reproductive Biology and Fertility (56 papers), Sperm and Testicular Function (49 papers), Ovarian function and disorders (34 papers), Calcium signaling and nucleotide metabolism (19 papers), Neuroscience and Neuropharmacology Research (18 papers) and Cardiovascular Effects of Exercise (17 papers). The work is most often cited by research in Reproductive Medicine (2.8k citations), Physiology (1.1k citations), Sensory Systems (786 citations), Cardiology and Cardiovascular Medicine (2.9k citations) and Cellular and Molecular Neuroscience (2.2k citations). F. Anthony Lai has collaborated with scholars based in United Kingdom, United States and Greece. Frequent co-authors include Karl Swann, Gerhard Meissner, Christopher M. Saunders, Lynda Blayney, John Parrington, Michail Nomikos, Mark G. Larman, Éric Rousseau, Harold Erickson and Christopher H. George. Their work appears in journals such as Biochemical Journal, Journal of Biological Chemistry, Biophysical Journal, Journal of Cell Science and Molecular Human Reproduction.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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