Eric M. Tam

3.1k total citations · 2 hit papers
23 papers, 2.5k citations indexed

About

Eric M. Tam is a scholar working on Cancer Research, Oncology and Immunology and Allergy. According to data from OpenAlex, Eric M. Tam has authored 23 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Cancer Research, 11 papers in Oncology and 7 papers in Immunology and Allergy. Recurrent topics in Eric M. Tam's work include Protease and Inhibitor Mechanisms (12 papers), Peptidase Inhibition and Analysis (8 papers) and Cell Adhesion Molecules Research (7 papers). Eric M. Tam is often cited by papers focused on Protease and Inhibitor Mechanisms (12 papers), Peptidase Inhibition and Analysis (8 papers) and Cell Adhesion Molecules Research (7 papers). Eric M. Tam collaborates with scholars based in Canada, United States and India. Eric M. Tam's co-authors include Christopher M. Overall, M. Sharon Stack, Yi Wu, Georgina S. Butler, G. Angus McQuibban, Christopher A. McCulloch, Jiang-Hong Gong, Ian Clark‐Lewis, Peter Friedl and Jörg Geiger and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Eric M. Tam

23 papers receiving 2.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

2007 770 citations Katarina Wolf, Yi Wu et al. Nature Cell Biology profile →
Inflammation Dampened by Gelatinase A Cleavage of Monocyte Chemoattractant Protein-3

2000 633 citations G. Angus McQuibban, Eric M. Tam et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Eric M. Tam Canada	13	1.2k	1.1k	894	603	498	23	2.5k
Charlotte Morrison Canada	23	1.2k 1.0×	919 0.8×	1.0k 1.1×	253 0.4×	281 0.6×	30	2.4k
Hidetoshi Mori United States	23	1.3k 1.1×	1.7k 1.5×	1.4k 1.5×	823 1.4×	602 1.2×	52	3.5k
Chris D. Madsen Sweden	19	666 0.6×	1.0k 0.9×	1.1k 1.2×	672 1.1×	230 0.5×	33	2.6k
Stephen J. Weiss United States	11	1.3k 1.1×	952 0.9×	856 1.0×	456 0.8×	628 1.3×	12	2.3k
Ute Reuning Germany	34	1.5k 1.3×	1.2k 1.1×	1.8k 2.1×	396 0.7×	1.3k 2.7×	83	4.3k
Amin Hajitou United Kingdom	29	569 0.5×	663 0.6×	1.7k 1.9×	295 0.5×	236 0.5×	64	3.0k
Enrica Balza Italy	29	512 0.4×	898 0.8×	1.4k 1.6×	359 0.6×	1.1k 2.2×	56	3.1k
Vishnu C. Ramani United States	23	850 0.7×	868 0.8×	1.5k 1.7×	853 1.4×	204 0.4×	31	2.6k
C.N. Rao United States	28	930 0.8×	765 0.7×	1.5k 1.7×	735 1.2×	1.7k 3.4×	37	3.4k
Frédéric Saltel France	34	480 0.4×	1.0k 0.9×	2.1k 2.4×	1.5k 2.5×	937 1.9×	73	4.4k

Countries citing papers authored by Eric M. Tam

Since Specialization

Citations

This map shows the geographic impact of Eric M. Tam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric M. Tam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric M. Tam more than expected).

Fields of papers citing papers by Eric M. Tam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric M. Tam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric M. Tam. The network helps show where Eric M. Tam may publish in the future.

Co-authorship network of co-authors of Eric M. Tam

This figure shows the co-authorship network connecting the top 25 collaborators of Eric M. Tam. A scholar is included among the top collaborators of Eric M. Tam based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric M. Tam. Eric M. Tam is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Sergeeva, Oksana A., Eric M. Tam, Guixian Jin, et al.. (2023). 1386 EVOLVE-106, a T cell engager with integrated CD2 costimulation targeting B7-H4, is a precision therapy for estrogen and Her2 receptor low breast cancers. SHILAP Revista de lepidopterología. A1541–A1541. 2 indexed citations

Tam, Eric M., Guixian Jin, Oksana A. Sergeeva, et al.. (2023). 1392 EVOLVE-104, a novel ULBP2-targeted T cell engager that integrates CD2 costimulation for the treatment of basal and squamous lineage tumors. SHILAP Revista de lepidopterología. A1547–A1547. 1 indexed citations

Kamoun, Walid S., Anne‐Sophie Dugast, James Suchy, et al.. (2019). Synergy between EphA2-ILs-DTXp, a Novel EphA2-Targeted Nanoliposomal Taxane, and PD-1 Inhibitors in Preclinical Tumor Models. Molecular Cancer Therapeutics. 19(1). 270–281. 15 indexed citations

Wong, Christina S.F., Jennifer Richards, Stephanie Grabow, et al.. (2019). Abstract 2491: Engineering and preclinical activity of MM-201, a best-in-class TRAIL receptor agonist. Cancer Research. 79(13_Supplement). 2491–2491. 2 indexed citations

Fulton, Ross B., Jennifer Richards, Christina S.F. Wong, et al.. (2019). Abstract 3270: Mechanism of action of a novel agonist TNFR2 antibody that induces co-stimulation of T cells and promotes robust anti-tumor immunity. Cancer Research. 79(13_Supplement). 3270–3270. 1 indexed citations

Paragas, Violette, Sandeep Kumar, Ross B. Fulton, et al.. (2019). Abstract 555: A novel human TNFR2 antibody (MM-401) modulates T cell responses in anti-cancer immunity. Cancer Research. 79(13_Supplement). 555–555. 6 indexed citations

Paragas, Violette, Ross B. Fulton, Jennifer Richards, et al.. (2019). Abstract 555: A novel human TNFR2 antibody (MM-401) modulates T cell responses in anti-cancer immunity. Immunology. 555–555. 1 indexed citations

Huang, Betty, Robyn Cotter, Eric M. Tam, et al.. (2013). Discovery of diverse and functional antibodies from large human repertoire antibody libraries. Journal of Immunological Methods. 391(1-2). 60–71. 38 indexed citations

Beaber, John W., et al.. (2011). A new helper phage for improved monovalent display of Fab molecules. Journal of Immunological Methods. 376(1-2). 46–54. 6 indexed citations

10.

Tam, Eric M., Lydia Santell, Clifford Quan, et al.. (2008). Noncompetitive Inhibition of Hepatocyte Growth Factor-dependent Met Signaling by a Phage-derived Peptide. Journal of Molecular Biology. 385(1). 79–90. 9 indexed citations

11.

Wolf, Katarina, Yi Wu, Yueying Liu, et al.. (2007). Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nature Cell Biology. 9(8). 893–904. 770 indexed citations breakdown →

12.

Tam, Eric M., Charlotte Morrison, Yi Wu, M. Sharon Stack, & Christopher M. Overall. (2004). Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1–matrix metalloproteinase substrates. Proceedings of the National Academy of Sciences. 101(18). 6917–6922. 236 indexed citations

13.

Overall, Christopher M., Eric M. Tam, Reinhild Kappelhoff, et al.. (2004). Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors. Biological Chemistry. 385(6). 493–504. 103 indexed citations

14.

Butler, Georgina S., Eric M. Tam, & Christopher M. Overall. (2004). The Canonical Methionine 392 of Matrix Metalloproteinase 2 (Gelatinase A) Is Not Required for Catalytic Efficiency or Structural Integrity. Journal of Biological Chemistry. 279(15). 15615–15620. 42 indexed citations

15.

Tam, Eric M., et al.. (2004). Characterization of the Distinct Collagen Binding, Helicase and Cleavage Mechanisms of Matrix Metalloproteinase 2 and 14 (Gelatinase A and MT1-MMP). Journal of Biological Chemistry. 279(41). 43336–43344. 138 indexed citations

16.

Tam, Eric M., Yi Wu, Georgina S. Butler, M. Sharon Stack, & Christopher M. Overall. (2002). Collagen Binding Properties of the Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Hemopexin C Domain. Journal of Biological Chemistry. 277(41). 39005–39014. 120 indexed citations

17.

Butler, Georgina S., Derek Sim, Eric M. Tam, Dana V. Devine, & Christopher M. Overall. (2002). Mannose-binding Lectin (MBL) Mutants Are Susceptible to Matrix Metalloproteinase Proteolysis. Journal of Biological Chemistry. 277(20). 17511–17519. 46 indexed citations

18.

Overall, Christopher M., Eric M. Tam, G. Angus McQuibban, et al.. (2000). Domain Interactions in the Gelatinase A·TIMP-2·MT1-MMP Activation Complex. Journal of Biological Chemistry. 275(50). 39497–39506. 82 indexed citations

19.

Overall, Christopher M., Heather F. Bigg, Tim T Y Lau, et al.. (1999). Identification of the TIMP‐2 Binding Site on the Gelatinase A Hemopexin C‐Domain by Site‐Directed Mutagenesis and the Yeast Two‐Hybrid System. Annals of the New York Academy of Sciences. 878(1). 747–753. 9 indexed citations

20.

Tam, Eric M. & Jack L. Pate. (1985). Amino Acid Transport by Prosthecae of Asticcacaulis biprosthecum: Evidence for a Broad-range Transport System. Microbiology. 131(10). 2687–2699. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact