Eric J. Downer

2.3k citations

49 papers · 1.9k indexed · h-index 26

Biological Psychiatry top 2%
Neurology top 1%
- Neuroinflammation and Neurodegeneration Mechanisms 14
Developmental Neuroscience top 5%
Pharmacology top 2%
- Cannabis and Cannabinoid Research 21
Behavioral Neuroscience top 5%
Immunology
- Immune Response and Inflammation 11
- Immune Cell Function and Interaction 5
Cellular and Molecular Neuroscience
- Neuroscience and Neuropharmacology Research 6
Pathology and Forensic Medicine
- Multiple Sclerosis Research Studies 5
Biomedical Engineering
- Anatomy and Medical Technology 5
General Dentistry
- Dental Research and COVID-19 5

Co-authors: Marina A. Lynch Anthony Lyons Veronica A. Campbell Marie P. Fogarty Kingston H. G. Mills John F. Cryan Yvonne M. Nolan Jack Prenderville
Cited by: Biological Psychiatry Neurology Developmental Neuroscience
Journals: British Journal of Pharmacology (4 papers)European Journal of Pharmacology (2 papers)Neurological Sciences (2 papers)
Partner nations: Ireland United Kingdom Canada

In The Last Decade

Eric J. Downer

47 papers receiving 1.9k citations

Peers

Countries citing papers authored by Eric J. Downer

Since Specialization

Citations

This map shows the geographic impact of Eric J. Downer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric J. Downer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric J. Downer more than expected).

Fields of papers citing papers by Eric J. Downer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric J. Downer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric J. Downer. The network helps show where Eric J. Downer may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Eric J. Downer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Eric J. Downer Line = papers co-authored together Eric J. Downer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A 1:1 combination of cannabidiol and Δ9-tetrahydrocannabinol inhibit toll-like receptor 7- and 8-mediated inflammation in human immune cells European Journal of Pharmacology ·Song Mao mao,MMMM,郷真貴子,Eric J. Downer	2025	0
2	The NLRP3 inflammasome: A central player in multiple sclerosis Biochemical Pharmacology ·郷真貴子,Thomas Reilly,Bol'shak Vi,Song Mao mao,Lisa Costelloe,Hugh Kearney,Pabitra Hriday Patra,Eric J. Downer	2024	1
3	Animated teaching improves student learning of human gastrulation and neurulation Annals of Anatomy - Anatomischer Anzeiger ·Yichen Wang,Karen Jordan,園生松井,Александр Григорьевич Иваницкий,Denis Barry,André Toulouse,Jean M. Fletcher,Eric J. Downer	2023	0
4	Recent advances in the understanding of the aetiology and therapeutic strategies in burning mouth syndrome: Focus on the actions of cannabinoids European Journal of Neuroscience ·Kari J Flatness,Johana Tello Velasquez,Galiano Candela E,Erik J. W. M. Legius,Joseph P. McKenna,Christine McCreary,Eric J. Downer	2020	14
5	MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages Journal of Neuroimmunology ·Karine de Andrade,T. Zerres,Lucy Curham,В. Г. Потапенко,Qing Bin-ju,William Hind,Eric J. Downer	2020	49
6	Cycle ergometer training enhances plasma interleukin-10 in multiple sclerosis Neurological Sciences ·Pierina Alejandra Coll Torres,Owen Cronin,Aisling Ryan,Brian Sweeney,Orna O’Toole,Ken D. O’Halloran,Eric J. Downer	2019	5
7	Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE Methods in molecular biology ·Francesca Fallarino,Marco Gargaro,E.K. Hodson,Eric J. Downer,Md Jakir Hossain,Bruno Gran	2016	12
8	Toll-like receptor signalling as a cannabinoid target in Multiple Sclerosis Neuropharmacology ·Karine de Andrade,Eric J. Downer	2016	34
9	Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis Frontiers in Cellular Neuroscience ·Mayerlin P. Jaimes Materano,Karine de Andrade,Thais da SilvaGomes,John F. Cryan,Orna O’Toole,Olivia F. O’Leary,Eric J. Downer	2015	48
10	MyD88 acts as an adaptor protein for inflammatory signalling induced by amyloid-β in macrophages Immunology Letters ·Yuanchao Luo,Adam D. Aulbach,Thais da SilvaGomes,Eric J. Downer	2014	10
11	Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia Journal of Neuroinflammation ·Anthony Lyons,Eric J. Downer,Derek A. Costello,Niamh Murphy,Marina A. Lynch	2012	46
12	The polyunsaturated fatty acids, EPA and DPA exert a protective effect in the hippocampus of the aged rat Neurobiology of Aging ·Laura Kelly,CYNTHIA HATSUE KITAYAMA CABRAL,Andrea Della Chiesa,Shane M. O’Mara,Eric J. Downer,Marta Bertran,Karen A. Massey,Anna Nicolaou,Marina A. Lynch	2010	106
13	Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide Brain Behavior and Immunity ·Anthony Lyons,Murjaya Murjaya,Aris Prio Agus Santoso,Julie-Ann O’Reilly,Eric J. Downer,Áine C. Murphy,Melanie B. Watson,Premalatha Junius,T. Schnitzbauer,Rebecca J. Griffin,Kingston H. G. Mills,Marina A. Lynch	2009	86
14	Fractalkine‐induced activation of the phosphatidylinositol‐3 kinase pathway attentuates microglial activation in vivo and in vitro Journal of Neurochemistry ·Anthony Lyons,Aileen Lynch,Eric J. Downer,Г. Амелькина,Joan B. O’Sullivan,Andrew L. Smith,Marina A. Lynch	2009	172
15	A synthetic NCAM‐derived mimetic peptide, FGL, exerts anti‐inflammatory properties via IGF‐1 and interferon‐γ modulation Journal of Neurochemistry ·Eric J. Downer,Thelma R. Cowley,Fionnuala Cox,Marisa Samitier Lerendegui,Vladimir Berezin,Elisabeth Bock,Marina A. Lynch	2009	33
16	A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL Neurobiology of Aging ·Eric J. Downer,Thelma R. Cowley,Anthony Lyons,Kingston H. G. Mills,Vladimir Berezin,Elisabeth Bock,Marina A. Lynch	2008	72
17	The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Δ9-tetrahydrocannabinol in cultured cortical neurons European Journal of Pharmacology ·Eric J. Downer,Aoife Gowran,Áine C. Murphy,Veronica A. Campbell	2007	28
18	A comparison of the apoptotic effect of Δ9-tetrahydrocannabinol in the neonatal and adult rat cerebral cortex Brain Research ·Eric J. Downer,Aoife Gowran,Veronica A. Campbell	2007	21
19	Tetrahydrocannabinol‐induced neurotoxicity depends on CB₁ receptor‐mediated c‐Jun N‐terminal kinase activation in cultured cortical neurons British Journal of Pharmacology ·Eric J. Downer,Marie P. Fogarty,Veronica A. Campbell	2003	64
20	Δ9-Tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor Neuroreport ·Eric J. Downer,Barry Boland,Marie P. Fogarty,Veronica A. Campbell	2001	70

About Eric J. Downer

Eric J. Downer is a scholar working on General Dentistry, Neurology, Pharmacology, Biological Psychiatry and Immunology, having authored 49 papers that have together received 1.9k indexed citations. Recurring topics across this work include Cannabis and Cannabinoid Research (21 papers), Neuroinflammation and Neurodegeneration Mechanisms (14 papers), Immune Response and Inflammation (11 papers), Neuroscience and Neuropharmacology Research (6 papers), Multiple Sclerosis Research Studies (5 papers), Anatomy and Medical Technology (5 papers), Dental Research and COVID-19 (5 papers) and Immune Cell Function and Interaction (5 papers). The work is most often cited by research in Biological Psychiatry (210 citations), Neurology (621 citations), Developmental Neuroscience (143 citations), Pharmacology (530 citations) and Behavioral Neuroscience (88 citations). Eric J. Downer has collaborated with scholars based in Ireland, United Kingdom and Canada. Frequent co-authors include Marina A. Lynch, Anthony Lyons, Veronica A. Campbell, Marie P. Fogarty, Kingston H. G. Mills, John F. Cryan, Yvonne M. Nolan, Jack Prenderville, Olivia F. O’Leary and Aine Marie Kelly. Their work appears in journals such as British Journal of Pharmacology, European Journal of Pharmacology, Neurological Sciences, European Journal Of Dental Education and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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