Eric Gouaux

30.2k total citations · 17 hit papers
141 papers, 23.4k citations indexed

About

Eric Gouaux is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Spectroscopy. According to data from OpenAlex, Eric Gouaux has authored 141 papers receiving a total of 23.4k indexed citations (citations by other indexed papers that have themselves been cited), including 113 papers in Molecular Biology, 84 papers in Cellular and Molecular Neuroscience and 15 papers in Spectroscopy. Recurrent topics in Eric Gouaux's work include Neuroscience and Neuropharmacology Research (77 papers), Ion channel regulation and function (45 papers) and Receptor Mechanisms and Signaling (33 papers). Eric Gouaux is often cited by papers focused on Neuroscience and Neuropharmacology Research (77 papers), Ion channel regulation and function (45 papers) and Receptor Mechanisms and Signaling (33 papers). Eric Gouaux collaborates with scholars based in United States, United Kingdom and Denmark. Eric Gouaux's co-authors include Toshimitsu Kawate, N. Armstrong, Satinder K. Singh, Ryan Hibbs, Atsuko Yamashita, Yan Jin, Hiroyasu Furukawa, Roderick MacKinnon, Kevin H. Wang and Aravind Penmatsa and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Eric Gouaux

139 papers receiving 23.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

2005 1.3k citations Atsuko Yamashita, Satinder K. Singh et al. profile →
Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH

2007 864 citations Eric Gouaux et al. profile →
Principles of Selective Ion Transport in Channels and Pumps

2005 817 citations Eric Gouaux et al. Science profile →
Principles of activation and permeation in an anion-selective Cys-loop receptor

2011 816 citations Eric Gouaux et al. profile →
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

2009 791 citations Eric Gouaux et al. profile →
Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor

2000 747 citations N. Armstrong, Eric Gouaux profile →
Structure of a glutamate transporter homologue from Pyrococcus horikoshii

2004 640 citations Eric Gouaux et al. profile →
Crystal structure of the ATP-gated P2X4 ion channel in the closed state

2009 620 citations Eric Gouaux et al. profile →
Subunit arrangement and function in NMDA receptors

2005 594 citations Satinder K. Singh, Eric Gouaux et al. profile →
Mechanism of glutamate receptor desensitization

2002 555 citations N. Armstrong, Eric Gouaux et al. profile →
Fluorescence-Detection Size-Exclusion Chromatography for Precrystallization Screening of Integral Membrane Proteins

2006 547 citations Eric Gouaux et al. Structure profile →
Structure of a glutamate-receptor ligand-binding core in complex with kainate

1998 523 citations N. Armstrong, Eric Gouaux et al. profile →
Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

2014 503 citations April Goehring, Isabelle Baconguis et al. profile →
X-ray structures and mechanism of the human serotonin transporter

2016 501 citations Jonathan A. Coleman, Eric Gouaux et al. profile →
X-ray structure of dopamine transporter elucidates antidepressant mechanism

2013 490 citations Eric Gouaux et al. profile →
Molecular mechanism of ATP binding and ion channel activation in P2X receptors

2012 455 citations Eric Gouaux et al. profile →
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel

2014 237 citations Isabelle Baconguis, Christopher J. Bohlen et al. Cell profile →

Peers

Countries citing papers authored by Eric Gouaux

Since Specialization

Citations

This map shows the geographic impact of Eric Gouaux's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric Gouaux with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric Gouaux more than expected).

Fields of papers citing papers by Eric Gouaux

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric Gouaux. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric Gouaux. The network helps show where Eric Gouaux may publish in the future.

Co-authorship network of co-authors of Eric Gouaux

This figure shows the co-authorship network connecting the top 25 collaborators of Eric Gouaux. A scholar is included among the top collaborators of Eric Gouaux based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric Gouaux. Eric Gouaux is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements 2025 ·Science Advances ·(unknown), Jun Hoe Kim, Beiying Liu, Gabriela Popescu, Eric Gouaux, Farzad Jalali‐Yazdi	2
2	Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses 2024 ·eLife ·Aya Matsui, Cathy J. Spangler, Johannes Elferich, Momoko Shiozaki, (unknown), Xiaowei Zhao, Maozhen Qin, Haining Zhong, Zhiheng Yu, Eric Gouaux	2
3	Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses 2024 ·eLife ·Aya Matsui, Cathy J. Spangler, Johannes Elferich, Momoko Shiozaki, (unknown), Xiaowei Zhao, Maozhen Qin, Haining Zhong, Zhiheng Yu, Eric Gouaux	11
4	Molecular mechanism of prestin electromotive signal amplification 2021 ·Cell ·Jingpeng Ge, Johannes Elferich, Sepehr Dehghani‐Ghahnaviyeh, Zhiyu Zhao, (unknown), Henrique von Gersdorff, Emad Tajkhorshid, Eric Gouaux	62
5	Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding 2021 ·Journal of Biological Chemistry ·(unknown), (unknown), Jonathan A. Coleman, Rong Zhu, Eric Gouaux, Michael Freissmuth, Walter Sandtner	10
6	The intracellular domain of homomeric glycine receptors modulates agonist efficacy 2020 ·Journal of Biological Chemistry ·(unknown), Remigijus Lapė, (unknown), Jie Yu, Hongtao Zhu, Eric Gouaux, Matthew G. Gold, (unknown)	17
7	Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM 2019 ·Science ·Yan Zhao, Shanshuang Chen, Adam Swensen, Weijun Qian, Eric Gouaux	137
8	Autoimmune receptor encephalitis in mice induced by active immunization with conformationally stabilized holoreceptors 2019 ·Science Translational Medicine ·(unknown), Kenneth R. Tovar, April Goehring, Farzad Jalali‐Yazdi, Nana J. Okada, Eric Gouaux, Gary L. Westbrook	59
9	Insights into the mechanism and pharmacology of neurotransmitter sodium symporters 2019 ·Current Opinion in Structural Biology ·Vikas Navratna, Eric Gouaux	47
10	Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5 2018 ·eLife ·Jingpeng Ge, Johannes Elferich, April Goehring, Huaying Zhao, Peter Schuck, Eric Gouaux	57
11	Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation 2017 ·Science ·(unknown), (unknown), April Goehring, Eric Gouaux	134
12	X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel breakdown → 2014 ·Cell ·Isabelle Baconguis, Christopher J. Bohlen, April Goehring, David Julius, Eric Gouaux	237
13	Structure and Mechanism of a Na ⁺ -Independent Amino Acid Transporter 2009 ·Science ·P.L. Shaffer, April Goehring, Aruna Shankaranarayanan, Eric Gouaux	267
14	A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation 2008 ·Science ·Satinder K. Singh, Chayne L. Piscitelli, Atsuko Yamashita, Eric Gouaux	350
15	Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor 2006 ·Cell ·N. Armstrong, (unknown), Mads Beich-Frandsen, Eric Gouaux	172
16	High resolution crystallographic studies of α‐hemolysin–phospholipid complexes define heptamer–lipid head group interactions: Implication for understanding protein–lipid interactions 2004 ·Protein Science ·Stefania Galdiero, Eric Gouaux	61
17	A new protein folding screen: Application to the ligand binding domains of a glutamate and kainate receptor and to lysozyme and carbonic anhydrase 1999 ·Protein Science ·N. Armstrong, Alexandre de Lencastre, Eric Gouaux	90
18	Single potassium ion seeks open channel for transmembrane travels: tales from the KcsA structure 1998 ·Structure ·Eric Gouaux	3
19	The long and short of colicin action: the molecular basis for the biological activity of channel-forming colicins 1997 ·Structure ·Eric Gouaux	29
20	α‐Hemolysin, γ‐hemolysin, and leukocidin from Staphylococcus aureus: Distant in sequence but similar in structure 1997 ·Protein Science ·Eric Gouaux, Michael R. Hobaugh, Langzhou Song	97

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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