Emmanuelle Comets

3.9k total citations · 1 hit paper
84 papers, 2.8k citations indexed

About

Emmanuelle Comets is a scholar working on Statistics and Probability, Oncology and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, Emmanuelle Comets has authored 84 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 39 papers in Statistics and Probability, 13 papers in Oncology and 12 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in Emmanuelle Comets's work include Statistical Methods in Clinical Trials (32 papers), Pharmacogenetics and Drug Metabolism (10 papers) and Statistical Methods and Bayesian Inference (10 papers). Emmanuelle Comets is often cited by papers focused on Statistical Methods in Clinical Trials (32 papers), Pharmacogenetics and Drug Metabolism (10 papers) and Statistical Methods and Bayesian Inference (10 papers). Emmanuelle Comets collaborates with scholars based in France, Germany and United Kingdom. Emmanuelle Comets's co-authors include France Mentré, Karl Brendel, Céline M. Laffont, Christian Laveille, Julie Bertrand, Nicholas H. G. Holford, Corinne Miceli‐Richard, É. Hachulla, Xavier Puéchal and Xavier Mariette and has published in prestigious journals such as Scientific Reports, Biometrics and Journal of Controlled Release.

In The Last Decade

Emmanuelle Comets

78 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics

2016 292 citations Thi Huyen Tram Nguyen, Samer Mouksassi et al. CPT Pharmacometrics & Systems Pharmacology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Emmanuelle Comets France	26	556	447	420	398	358	84	2.8k
Andrew C. Hooker Sweden	21	741 1.3×	568 1.3×	531 1.3×	543 1.4×	421 1.2×	109	3.8k
Martin Bergstrand Sweden	17	487 0.9×	175 0.4×	376 0.9×	425 1.1×	315 0.9×	38	2.5k
Ene Ette United States	24	436 0.8×	375 0.8×	423 1.0×	411 1.0×	252 0.7×	68	2.1k
Marc Pfister Switzerland	33	600 1.1×	161 0.4×	600 1.4×	250 0.6×	379 1.1×	184	3.9k
Radojka M. Savić United States	25	656 1.2×	251 0.6×	493 1.2×	484 1.2×	1.2k 3.2×	89	3.3k
Ron J. Keizer Netherlands	20	386 0.7×	124 0.3×	295 0.7×	364 0.9×	254 0.7×	60	2.0k
David Z. D’Argenio United States	26	384 0.7×	260 0.6×	180 0.4×	326 0.8×	294 0.8×	96	2.3k
Ulrika S. H. Simonsson Sweden	29	619 1.1×	139 0.3×	368 0.9×	354 0.9×	1.0k 2.8×	114	2.6k
Iñaki F. Trocóniz Spain	31	423 0.8×	181 0.4×	263 0.6×	887 2.2×	92 0.3×	187	3.6k
DR Mould United States	7	287 0.5×	225 0.5×	202 0.5×	225 0.6×	117 0.3×	7	1.5k

Countries citing papers authored by Emmanuelle Comets

Since Specialization

Citations

This map shows the geographic impact of Emmanuelle Comets's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Emmanuelle Comets with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Emmanuelle Comets more than expected).

Fields of papers citing papers by Emmanuelle Comets

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Emmanuelle Comets. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Emmanuelle Comets. The network helps show where Emmanuelle Comets may publish in the future.

Co-authorship network of co-authors of Emmanuelle Comets

This figure shows the co-authorship network connecting the top 25 collaborators of Emmanuelle Comets. A scholar is included among the top collaborators of Emmanuelle Comets based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Emmanuelle Comets. Emmanuelle Comets is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Röver, Christian, Emmanuelle Comets, Markus C. Elze, et al.. (2025). In Silico Clinical Trials in Drug Development: A Systematic Review. Therapeutic Innovation & Regulatory Science. 60(2). 423–439.

Woillard, Jean‐Baptiste, Sébastien Benzekry, Julie Josse, et al.. (2025). Digital pharmacological twins: Bridging multi-scale modelling and artificial intelligence for precision medicine: The DIGPHAT consortium. Therapies. 81(2). 147–158.

Comets, Emmanuelle, et al.. (2024). Joint modeling of tumor dynamics and progression‐free survival in advanced breast cancer: Leveraging data from amcenestrant early phase I–II trials. CPT Pharmacometrics & Systems Pharmacology. 13(6). 941–953. 2 indexed citations

Comets, Emmanuelle, Antoine Guillon, Robin Michelet, et al.. (2024). Straightforward Phase I Dose-Finding Design for Healthy Volunteers Accounting for Surrogate Activity Biomarkers. Statistics in Biopharmaceutical Research. 17(3). 496–505.

Baldolli, Aurélie, Christian Créveuil, Jean‐Jacques Parienti, et al.. (2024). Pharmacokinetics and safety of daptomycin administered subcutaneously in healthy volunteers: a single-blinded randomized crossover trial. Journal of Antimicrobial Chemotherapy. 79(11). 3016–3022. 3 indexed citations

Hooker, Andrew C., Emmanuelle Comets, Andreas Traschütz, et al.. (2024). Longitudinal Analysis of Natural History Progression of Rare and Ultra‐Rare Cerebellar Ataxias Using Item Response Theory. Clinical Pharmacology & Therapeutics. 116(6). 1593–1605. 2 indexed citations

Comets, Emmanuelle, et al.. (2023). Multivariate Exact Discrepancy: A New Tool for PK/PD Model Evaluation. Clinical Pharmacokinetics. 62(11). 1599–1609. 3 indexed citations

Lemaı̂tre, F., Marie‐Claude Gagnieu, François Parant, et al.. (2023). Therapeutic drug monitoring and virological response at week 48 in a cohort of HIV‐1‐infected patients switching to dolutegravir/rilpivirine dual maintenance therapy (ANRS‐MIE‐BIRIDER study). British Journal of Clinical Pharmacology. 90(1). 264–273.

Michelet, Robin, Moreno Ursino, Mara Baldry, et al.. (2021). The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia. Pharmaceutics. 13(5). 601–601. 2 indexed citations

10.

Lemaı̂tre, F., F. Fily, Matthieu Revest, et al.. (2021). Development of a dosing-adjustment tool for fluoroquinolones in osteoarticular infections: The Fluo-pop study. Biomedicine & Pharmacotherapy. 142. 112053–112053. 1 indexed citations

11.

Bizzotto, Roberto, et al.. (2017). PharmML in Action: an Interoperable Language for Modeling and Simulation. CPT Pharmacometrics & Systems Pharmacology. 6(10). 651–665. 5 indexed citations

12.

Comets, Emmanuelle, Audrey Lavenu, & Marc Lavielle. (2017). Parameter Estimation in Nonlinear Mixed Effect Models Using saemix, an R Implementation of the SAEM Algorithm. Journal of Statistical Software. 80(3). 73 indexed citations

13.

Nguyen, Thi Huyen Tram, Samer Mouksassi, Nicholas H. G. Holford, et al.. (2016). Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics. CPT Pharmacometrics & Systems Pharmacology. 6(2). 87–109. 292 indexed citations breakdown →

14.

Bertrand, Julie, et al.. (2015). Comparison of Nonlinear Mixed Effects Models and Noncompartmental Approaches in Detecting Pharmacogenetic Covariates. The AAPS Journal. 17(3). 597–608. 6 indexed citations

15.

Bertrand, Julie, Emmanuelle Comets, Marylore Chenel, & France Mentré. (2011). Some Alternatives to Asymptotic Tests for the Analysis of Pharmacogenetic Data Using Nonlinear Mixed Effects Models. Biometrics. 68(1). 146–155. 12 indexed citations

16.

Comets, Emmanuelle & Karl Brendel. (2010). Model evaluation in nonlinear mixed effect models, with applications to pharmacokinetics. French digital mathematics library (Numdam). 151(1). 106–128. 29 indexed citations

17.

Comets, Emmanuelle & Sarah Zohar. (2009). A Survey of the Way Pharmacokinetics are Reported in Published Phase I Clinical Trials, with an Emphasis on Oncology. Clinical Pharmacokinetics. 48(6). 387–395. 13 indexed citations

18.

Comets, Emmanuelle, Karl Brendel, & France Mentré. (2008). Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R. Computer Methods and Programs in Biomedicine. 90(2). 154–166. 380 indexed citations

19.

Brendel, Karl, Emmanuelle Comets, Céline M. Laffont, et al.. (2007). Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey. British Journal of Clinical Pharmacology. 64(5). 603–612. 70 indexed citations

20.

Aymard, Guy, et al.. (1998). Rapid and simple micromethod for the quantification of fluindione in human plasma using high-performance liquid chromatography. Journal of Chromatography B Biomedical Sciences and Applications. 707(1-2). 169–173. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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