Emmanuelle Comets

3.9k citations

84 papers · 2.8k indexed · 1 hit paper · h-index 26

Impact in

Statistics and Probability top 1%
- Statistical Methods in Clinical Trials
Pharmacology top 2%
- Antibiotics Pharmacokinetics and Efficacy
- Pharmacogenetics and Drug Metabolism

Papers in ⓘ

Statistics and Probability 39
- Statistical Methods in Clinical Trials 32
- Statistical Methods and Bayesian Inference 10
- Statistical Methods and Inference 9
Pharmacology 10
- Pharmacogenetics and Drug Metabolism 10
- Antibiotics Pharmacokinetics and Efficacy 9

Co-authors: France Mentré (37 shared papers)Karl Brendel (7 shared papers)Céline M. Laffont (6 shared papers)Christian Laveille (3 shared papers)Julie Bertrand (9 shared papers)Nicholas H. G. Holford (3 shared papers)Corinne Miceli‐Richard (4 shared papers)Xavier Mariette (4 shared papers)
Journals: CPT Pharmacometrics & Systems Pharmacology (8 papers)The AAPS Journal (7 papers)Journal of Pharmacokinetics and Pharmacodynamics (6 papers)Antimicrobial Agents and Chemotherapy (5 papers)British Journal of Clinical Pharmacology (4 papers)
Partner nations: France Germany United Kingdom

In The Last Decade

Emmanuelle Comets

78 papers receiving 2.7k citations

Hit Papers

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Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics 2016 · 292 citations

Peers

Countries citing papers authored by Emmanuelle Comets

Since Specialization

Citations

This map shows the geographic impact of Emmanuelle Comets's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Emmanuelle Comets with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Emmanuelle Comets more than expected).

Fields of papers citing papers by Emmanuelle Comets

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Emmanuelle Comets. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Emmanuelle Comets. The network helps show where Emmanuelle Comets may publish in the future.

Co-authors

The 25 scholars most cited alongside Emmanuelle Comets, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Emmanuelle Comets Line = papers co-authored together Emmanuelle Comets links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 84 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R Computer Methods and Programs in Biomedicine ·Emmanuelle Comets, Karl Brendel, France Mentré	2008	380
2	Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics CPT Pharmacometrics & Systems Pharmacology ·Thi Huyen Tram Nguyen, Samer Mouksassi, Nicholas H. G. Holford, Nidal Al‐Huniti, Immanuel Freedman, Andrew C. Hooker, Johina M. John, Mats O. Karlsson, Diane R. Mould, Juan José Pérez Ruixo, Elodie L. Plan, Radojka M. Savić, J. G. Coen van Hasselt, Benjamin Weber, Congya Zhou, Emmanuelle Comets, France Mentré Hit paper breakdown →	2016	292
3	Metrics for External Model Evaluation with an Application to the Population Pharmacokinetics of Gliclazide Pharmaceutical Research ·Karl Brendel, Emmanuelle Comets, Céline M. Laffont, Christian Laveille, France Mentré	2006	263
4	Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load CPT Pharmacometrics & Systems Pharmacology ·António Gonçalves, Julie Bertrand, Ruian Ke, Emmanuelle Comets, Xavier de Lamballerie, Denis Malvy, Andrés Pizzorno, Olivier Terrier, Manuel Rosa‐Calatrava, France Mentré, Patrick F. Smith, Alan S. Perelson, Jérémie Guedj	2020	150
5	Are Population Pharmacokinetic and/or Pharmacodynamic Models Adequately Evaluated? Clinical Pharmacokinetics ·Karl Brendel, Céline Dartois, Emmanuelle Comets, Annabelle Lemenuel‐Diot, Christian Laveille, Brigitte Tranchand, Pascal Girard, Céline M. Laffont, (unknown)	2007	145
6	Association of an IRF5 gene functional polymorphism with Sjögren's syndrome Arthritis & Rheumatism ·Corinne Miceli‐Richard, Emmanuelle Comets, Pascale Loiseau, Xavier Puéchal, É. Hachulla, Xavier Mariette	2007	121
7	The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome Arthritis & Rheumatism ·Corinne Miceli‐Richard, Nicolas Gestermann, Marc Ittah, Emmanuelle Comets, Pascale Loiseau, Xavier Puéchal, É. Hachulla, Jacques‐Eric Gottenberg, Pierre Lebon, Laurent Becquemont, Xavier Mariette	2009	74
8	Parameter Estimation in Nonlinear Mixed Effect Models Using saemix, an R Implementation of the SAEM Algorithm Journal of Statistical Software ·Emmanuelle Comets, Audrey Lavenu, Marc Lavielle	2017	73
9	Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey British Journal of Clinical Pharmacology ·Céline Dartois, Karl Brendel, Emmanuelle Comets, Céline M. Laffont, Christian Laveille, Brigitte Tranchand, France Mentré, Annabelle Lemenuel‐Diot, Pascal Girard	2007	70
10	A comparison of bootstrap approaches for estimating uncertainty of parameters in linear mixed‐effects models Pharmaceutical Statistics ·Hoai‐Thu Thai, France Mentré, Nicholas H. G. Holford, Christine Veyrat‐Follet, Emmanuelle Comets	2013	67
11	Evaluation of different tests based on observations for external model evaluation of population analyses Journal of Pharmacokinetics and Pharmacodynamics ·Karl Brendel, Emmanuelle Comets, Céline M. Laffont, France Mentré	2009	66
12	New Colistin Population Pharmacokinetic Data in Critically Ill Patients Suggesting an Alternative Loading Dose Rationale Antimicrobial Agents and Chemotherapy ·Nicolas Grégoire, Olivier Mimoz, Bruno Mégarbane, Emmanuelle Comets, Delphine Chatelier, Sigismond Lasocki, R. Gauzit, Dorothée Balayn, P. Gobin, Sandrine Marchand, William Couet	2014	66
13	A single tumour necrosis factor haplotype influences the response to adalimumab in rheumatoid arthritis Annals of the Rheumatic Diseases ·Corinne Miceli‐Richard, Emmanuelle Comets, Céline Verstuyft, Ryad Tamouza, Philippe M. Loiseau, Philippe Ravaud, H. Küpper, Laurent Becquemont, Dominique Charron, Xavier Mariette	2007	65
14	STAT4 is a confirmed genetic risk factor for Sjögren's syndrome and could be involved in type 1 interferon pathway signaling Genes and Immunity ·Nicolas Gestermann, A. Mékinian, Emmanuelle Comets, Philippe M. Loiseau, Xavier Puéchal, É. Hachulla, J-E Gottenberg, Xavier Mariette, Corinne Miceli‐Richard	2010	62
15	Design in nonlinear mixed effects models: Optimization using the Fedorov–Wynn algorithm and power of the Wald test for binary covariates Statistics in Medicine ·Sylvie Retout, Emmanuelle Comets, Adeline Samson, France Mentré	2007	58
16	Cerebral uptake of mefloquine enantiomers with and without the P‐gp inhibitor elacridar (GF1210918) in mice British Journal of Pharmacology ·Sylvie Barraud de Lagerie, Emmanuelle Comets, Céline Gautrand, Christine Fernandez, Daniel Auchère, E Singlas, France Mentré, François Gimenez	2004	57
17	Evaluation of bootstrap methods for estimating uncertainty of parameters in nonlinear mixed-effects models: a simulation study in population pharmacokinetics Journal of Pharmacokinetics and Pharmacodynamics ·Hoai‐Thu Thai, France Mentré, Nicholas H. G. Holford, Christine Veyrat-Follet, Emmanuelle Comets	2013	51
18	Dose‐finding methods for Phase I clinical trials using pharmacokinetics in small populations Biometrical Journal ·Moreno Ursino, Sarah Zohar, Frederike Lentz, Corinne Alberti, Tim Friede, Nigel Stallard, Emmanuelle Comets	2017	41
19	Population Pharmacokinetic-Pharmacogenetic Study of Nevirapine in HIV-Infected Cambodian Patients Antimicrobial Agents and Chemotherapy ·Monidarin Chou, Julie Bertrand, Olivier Ségéral, Céline Verstuyft, Laurence Borand, Emmanuelle Comets, Clotilde Le Tiec, Laurent Becquemont, Vara Ouk, France Mentré, Anne‐Marie Taburet	2010	34
20	Comparison of Model-Based Tests and Selection Strategies to Detect Genetic Polymorphisms Influencing Pharmacokinetic Parameters Journal of Biopharmaceutical Statistics ·Julie Bertrand, Emmanuelle Comets, France Mentré	2008	33

About Emmanuelle Comets

Emmanuelle Comets is a scholar working on Statistics and Probability, Pharmacology, Virology, Management Science and Operations Research and Pediatrics, Perinatology and Child Health, having authored 84 papers that have together received 2.8k indexed citations. Recurring topics across this work include Statistical Methods in Clinical Trials (32 papers), Statistical Methods and Bayesian Inference (10 papers), Pharmacogenetics and Drug Metabolism (10 papers), Drug Transport and Resistance Mechanisms (10 papers), Statistical Methods and Inference (9 papers), Antibiotics Pharmacokinetics and Efficacy (9 papers), Optimal Experimental Design Methods (8 papers) and Pharmaceutical studies and practices (7 papers). The work is most often cited by research in Statistics and Probability (447 citations), Pharmacology (556 citations), Molecular Medicine (161 citations), Transplantation (77 citations) and Pharmacology (233 citations). Emmanuelle Comets has collaborated with scholars based in France, Germany and United Kingdom. Frequent co-authors include France Mentré, Karl Brendel, Céline M. Laffont, Christian Laveille, Julie Bertrand, Nicholas H. G. Holford, Corinne Miceli‐Richard, Xavier Mariette, Xavier Puéchal and É. Hachulla. Their work appears in journals such as CPT Pharmacometrics & Systems Pharmacology, The AAPS Journal, Journal of Pharmacokinetics and Pharmacodynamics, Antimicrobial Agents and Chemotherapy and British Journal of Clinical Pharmacology.

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