Elizabeth A. Lyle

2.3k citations

24 papers · 1.6k indexed · h-index 17

Infectious Diseases top 2%
Immunology top 5%
Molecular Biology
Microbiology top 2%
Pulmonary and Respiratory Medicine top 10%

Co-authors: Robert A. Weinstein Donald Blom Mary K. Hayden Richard I. Tapping Katherine Omueti Ayoade David van de Vijver Marc J. M. Bonten C. Mark Johnson
Topics: Chemical Synthesis and Analysis (6 papers)Peptidase Inhibition and Analysis (6 papers)Immune Response and Inflammation (6 papers)
Cited by: Microbiology Applied Microbiology and Biotechnology Infectious Diseases
Journals: Journal of Biological Chemistry The Journal of Immunology Clinical Infectious Diseases
Partner nations: United States Canada United Kingdom

In The Last Decade

Elizabeth A. Lyle

24 papers receiving 1.5k citations

Peers

Countries citing papers authored by Elizabeth A. Lyle

Since Specialization

Citations

This map shows the geographic impact of Elizabeth A. Lyle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Elizabeth A. Lyle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Elizabeth A. Lyle more than expected).

Fields of papers citing papers by Elizabeth A. Lyle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Elizabeth A. Lyle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Elizabeth A. Lyle. The network helps show where Elizabeth A. Lyle may publish in the future.

Co-authorship network of co-authors of Elizabeth A. Lyle

This figure shows the co-authorship network connecting the top 25 collaborators of Elizabeth A. Lyle. A scholar is included among the top collaborators of Elizabeth A. Lyle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Elizabeth A. Lyle. Elizabeth A. Lyle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	P3 optimization of functional potency, in vivo efficacy and oral bioavailability in 3-aminopyrazinone thrombin inhibitors bearing non-charged groups at the P1 position 2010 ·Bioorganic & Medicinal Chemistry Letters ·Richard C.A. Isaacs,(unknown),(unknown),Swati P. Mercer,Bruce D. Dorsey,Colleen M. McDonough,Jacquelynn J. Cook,Julie A. Krueger,Sidney D. Lewis,Bobby J. Lucas,Elizabeth A. Lyle,Joseph J. Lynch,Cynthia Miller‐Stein,(unknown),Audrey A. Wallace,Rebecca B. White,Bradley K. Wong	3
2	Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·Richard C.A. Isaacs,(unknown),(unknown),Swati P. Mercer,Linda S. Payne,Kenneth J. Stauffer,Peter Williams,Jacquelynn J. Cook,Julie A. Krueger,Sidney D. Lewis,Bobby J. Lucas,Elizabeth A. Lyle,Joseph J. Lynch,Daniel R. McMasters,Adel M. Naylor-Olsen,(unknown),Audrey A. Wallace	6
3	Characterization of the cell surface glycolipid from Spirochaeta aurantia 2009 ·Glycoconjugate Journal ·Catherine J. Paul,Elizabeth A. Lyle,Terry J. Beveridge,Richard I. Tapping,Andrew M. Kropinski,Evgeny Vinogradov	3
4	Cutting Edge: A Common Polymorphism Impairs Cell Surface Trafficking and Functional Responses of TLR1 but Protects against Leprosy 2007 ·The Journal of Immunology ·C. Mark Johnson,Elizabeth A. Lyle,Katherine Omueti Ayoade,(unknown),Olcay Yeğin,Erkan Alpsoy,Lutz Hamann,Ralf R. Schumann,Richard I. Tapping	211
5	Risk of Hand or Glove Contamination After Contact With Patients Colonized With Vancomycin-Resistant Enterococcus or the Colonized Patients' Environment 2007 ·Infection Control and Hospital Epidemiology ·Mary K. Hayden,Donald Blom,Elizabeth A. Lyle,Charity G. Moore,Robert A. Weinstein	232
6	Identification and Characterization of 4-Methylbenzyl 4-[(Pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an Orally Bioavailable, Brain Penetrant NR2B SelectiveN-Methyl-d-Aspartate Receptor Antagonist 2007 ·Journal of Medicinal Chemistry ·Nigel J. Liverton,Rodney A. Bednar,Bohumil Bednář,John W. Butcher,Christopher F. Claiborne,David A. Claremon,Michael E. Cunningham,Anthony G. DiLella,Stanley L. Gaul,Brian E. Libby,Elizabeth A. Lyle,Joseph J. Lynch,John A. McCauley,Scott D. Mosser,Kevin T. Nguyen,Gary L. Stump,Hong Sun,Hao Wang,James A. Yergey,Kenneth S. Koblan	32
7	Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus 2006 ·Cellular Microbiology ·George Hajishengallis,Richard I. Tapping,Evlambia Harokopakis,(unknown),(unknown),Robert E. Schifferle,Elizabeth A. Lyle,Martha Triantafilou,Kathy Triantafilou,Fuminobu Yoshimura	155
8	Reduction in Acquisition of Vancomycin-Resistant Enterococcus after Enforcement of Routine Environmental Cleaning Measures 2006 ·Clinical Infectious Diseases ·Mary K. Hayden,Marc J. M. Bonten,Donald Blom,Elizabeth A. Lyle,David van de Vijver,Robert A. Weinstein	291
9	Domain Exchange between Human Toll-like Receptors 1 and 6 Reveals a Region Required for Lipopeptide Discrimination 2005 ·Journal of Biological Chemistry ·Katherine Omueti Ayoade,(unknown),C. Mark Johnson,Elizabeth A. Lyle,Richard I. Tapping	121
10	Low molecular weight thrombin inhibitors with excellent potency, metabolic stability, and oral bioavailability 2004 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Kenneth J. Stauffer,Peter Williams,Terry A. Lyle,Joseph P. Vacca,Julie A. Krueger,Sidney D. Lewis,Bobby J. Lucas,Bradley K. Wong,Rebecca B. White,Cynthia Miller‐Stein,Elizabeth A. Lyle,Audrey A. Wallace,Yvonne Leonard,(unknown),Joseph J. Lynch,Daniel R. McMasters	16
11	The structure and biological characteristics of the Spirochaeta aurantia outer membrane glycolipid LGL_B 2004 ·European Journal of Biochemistry ·Evgeny Vinogradov,Catherine J. Paul,Jianjun Li,Yuchen Zhou,Elizabeth A. Lyle,Richard I. Tapping,Andrew M. Kropinski,Malcolm B. Perry	6
12	3-Amino-4-sulfonylpyridinone acetamide and related pyridothiadiazine thrombin inhibitors 2003 ·Bioorganic & Medicinal Chemistry Letters ·Philip E.J. Sanderson,(unknown),(unknown),Adel M. Naylor-Olsen,(unknown),(unknown),Franklin C. Clayton,Julie A. Krueger,Sidney D. Lewis,Bobby J. Lucas,Elizabeth A. Lyle,Audrey A. Wallace,(unknown),Youwei Yan	8
13	Differential effects of sodium nitroprusside and hydralazine in a rat model of topical FeCl3-induced carotid artery thrombosis 2003 ·Thrombosis Research ·Mary Ann Robinson,(unknown),(unknown),Joseph J. Lynch,Elizabeth A. Lyle	13
14	Bicyclic pyridones as potent, efficacious and orally bioavailable thrombin inhibitors 2000 ·Bioorganic & Medicinal Chemistry Letters ·Craig A. Coburn,(unknown),Peter Williams,Carl F. Homnick,Elizabeth A. Lyle,Sidney D. Lewis,Bobby J. Lucas,(unknown),(unknown),Julie A. Krueger,Kari Vastag,I‐Wu Chen,Joseph P. Vacca	19
15	L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor 1998 ·Bioorganic & Medicinal Chemistry Letters ·Philip E.J. Sanderson,(unknown),Bruce D. Dorsey,(unknown),Colleen M. McDonough,Adel M. Naylor-Olsen,I‐Wu Chen,Zhongguo Chen,Jacquelynn J. Cook,(unknown),Julie A. Krueger,Sidney D. Lewis,Jiunn H. Lin,Bobby J. Lucas,Elizabeth A. Lyle,Joseph J. Lynch,Maria T. Stranieri,Kari Vastag,Jules A. Shafer,(unknown)	51
16	C6 Modification of the pyridinone core of thrombin inhibitor L-374,087 as a means of enhancing its oral absorption 1998 ·Bioorganic & Medicinal Chemistry Letters ·Richard C.A. Isaacs,(unknown),(unknown),Philip E.J. Sanderson,(unknown),Elizabeth Baskin,I‐Wu Chen,(unknown),Jacquelynn J. Cook,(unknown),Sidney D. Lewis,Robert J. Lucas,Elizabeth A. Lyle,Joseph J. Lynch,Adel M. Naylor-Olsen,Maria T. Stranieri,Kari Vastag,(unknown)	19
17	Discovery and Development of the Novel Potent Orally Active Thrombin Inhibitor N-(9-Hydroxy-9-fluorenecarboxy)prolyl trans-4-Aminocyclohexylmethyl Amide (L-372,460): Coapplication of Structure-Based Design and Rapid Multiple Analogue Synthesis on Solid Support 1998 ·Journal of Medicinal Chemistry ·Stephen F. Brady,Kenneth J. Stauffer,William C. Lumma,Graham Smith,Harri G. Ramjit,Sidney D. Lewis,Bobby J. Lucas,(unknown),Elizabeth A. Lyle,(unknown),Jacquelynn J. Cook,Marie A. Holahan,Maria T. Stranieri,Joseph J. Lynch,Jiunn H. Lin,(unknown),Kari Vastag,Adel M. Naylor-Olsen,Joseph P. Vacca	59
18	Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor 1997 ·Bioorganic & Medicinal Chemistry Letters ·Terry A. Lyle,Zhongguo Chen,(unknown),Roger Freidinger,Stephen J. Gardell,Sidney D. Lewis,Ying Li,Elizabeth A. Lyle,Joseph J. Lynch,A. M. Mulichak,(unknown),Adel M. Naylor-Olsen,William M. Sanders	34
19	L-373,890, An achiral, noncovalent, subnanomolar thrombin inhibitor 1997 ·Bioorganic & Medicinal Chemistry Letters ·Philip E.J. Sanderson,(unknown),Adel M. Naylor-Olsen,Joseph P. Vacca,(unknown),Sidney D. Lewis,Bobby J. Lucas,Elizabeth A. Lyle,Joseph J. Lynch,A. M. Mulichak	32
20	Inhibition of Thrombin by Peptides Containing Lysyl-α-Keto Carbonyl Derivatives 1995 ·Thrombosis and Haemostasis ·(unknown),(unknown),Elizabeth A. Lyle,Michael J. Mellott,(unknown),Stephen F. Brady,Kenneth J. Stauffer,John T. Sisko,Shi‐Shan Mao,Daniel F. Veber,Ruth F. Nutt,Joseph J. Lynch,Jacquelynn J. Cook,(unknown),Jules A. Shafer	23

About Elizabeth A. Lyle

Elizabeth A. Lyle is a scholar working on Hematology, Immunology and Organic Chemistry, having authored 24 papers that have together received 1.6k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (6 papers), Peptidase Inhibition and Analysis (6 papers) and Immune Response and Inflammation (6 papers). The work is most often cited by research in Microbiology (271 citations), Applied Microbiology and Biotechnology (72 citations) and Infectious Diseases (578 citations). Elizabeth A. Lyle has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Robert A. Weinstein, Donald Blom, Mary K. Hayden, Richard I. Tapping, Katherine Omueti Ayoade, David van de Vijver, Marc J. M. Bonten, C. Mark Johnson, Charity G. Moore and Joseph J. Lynch. Their work appears in journals such as Journal of Biological Chemistry, The Journal of Immunology and Clinical Infectious Diseases.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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