Edwin R. Smith

10.2k citations

57 papers · 7.6k indexed · 2 hit papers · h-index 43

Impact in

Molecular Biology top 0.5%
- Genomics and Chromatin Dynamics
- Epigenetics and DNA Methylation
- RNA Research and Splicing
- RNA modifications and cancer
- Cancer-related gene regulation
- Protein Degradation and Inhibitors
- Ubiquitin and proteasome pathways
- Histone Deacetylase Inhibitors Research
Aging top 5%

Papers in ⓘ

Molecular Biology 54
- Genomics and Chromatin Dynamics 39
- Epigenetics and DNA Methylation 25
- Cancer-related gene regulation 19
- RNA Research and Splicing 15
- RNA modifications and cancer 10
- Protein Degradation and Inhibitors 7
- CRISPR and Genetic Engineering 4
Genetics 5

Co-authors: Ali Shilatifard (43 shared papers)Chengqi Lin (10 shared papers)John C. Lucchesi (9 shared papers)C. David Allis (5 shared papers)Sukesh R. Bhaumik (1 shared paper)Jung‐Shin Lee (2 shared papers)Fei Chen (4 shared papers)Michael P. Washburn (9 shared papers)
Journals: Molecular and Cellular Biology (11 papers)Genes & Development (8 papers)Molecular Cell (7 papers)Cell (6 papers)Nature Structural & Molecular Biology (3 papers)
Partner nations: United States Canada Spain

In The Last Decade

Edwin R. Smith

57 papers receiving 7.5k citations

Hit Papers

align trajectories log scale

Covalent modifications of histones during development and disease pathogenesis 2007 · 511 citations

Peers

Countries citing papers authored by Edwin R. Smith

Since Specialization

Citations

This map shows the geographic impact of Edwin R. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edwin R. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edwin R. Smith more than expected).

Fields of papers citing papers by Edwin R. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edwin R. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edwin R. Smith. The network helps show where Edwin R. Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Edwin R. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edwin R. Smith Line = papers co-authored together Edwin R. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 57 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Physical Association and Coordinate Function of the H3 K4 Methyltransferase MLL1 and the H4 K16 Acetyltransferase MOF Cell ·Yali Dou, Thomas A. Milne, Alan J. Tackett, Edwin R. Smith, Aya Fukuda, Joanna Wysocka, C. David Allis, Brian T. Chait, Jay L. Hess, Robert G. Roeder Hit paper breakdown →	2005	532
2	Covalent modifications of histones during development and disease pathogenesis Nature Structural & Molecular Biology ·Sukesh R. Bhaumik, Edwin R. Smith, Ali Shilatifard Hit paper breakdown →	2007	511
3	AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia Molecular Cell ·Chengqi Lin, Edwin R. Smith, Hidehisa Takahashi, Ka Chun Lai, Skylar Martin‐Brown, Laurence Florens, Michael P. Washburn, Joan Conaway, Ronald Conaway, Ali Shilatifard	2010	443
4	The Language of Histone Crosstalk Cell ·Jung‐Shin Lee, Edwin R. Smith, Ali Shilatifard	2010	434
5	The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers Molecular and Cellular Biology ·Deqing Hu, Xin Gao, Marc A. Morgan, Hans-Martin Herz, Edwin R. Smith, Ali Shilatifard	2013	304
6	Born to run: control of transcription elongation by RNA polymerase II Nature Reviews Molecular Cell Biology ·Fei Chen, Edwin R. Smith, Ali Shilatifard	2018	286
7	Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II Molecular and Cellular Biology ·Pengfei Wang, Chengqi Lin, Edwin R. Smith, Hong Guo, Brian W. Sanderson, Min Wu, Madelaine Gogol, Tara B. Alexander, Christopher Seidel, Leanne M. Wiedemann, Kai Ge, Robb Krumlauf, Ali Shilatifard	2009	285
8	ESA1 is a histone acetyltransferase that is essential for growth in yeast Proceedings of the National Academy of Sciences ·Edwin R. Smith, Arri Eisen, Weigang Gu, Martin Sattah, Antonio Pannuti, Zhou Jian-xin, Richard G. Cook, John C. Lucchesi, C. David Allis	1998	272
9	The Drosophila MSL Complex Acetylates Histone H4 at Lysine 16, a Chromatin Modification Linked to Dosage Compensation Molecular and Cellular Biology ·Edwin R. Smith, Antonio Pannuti, Weigang Gu, Arnd Steurnagel, Richard G. Cook, C. David Allis, John C. Lucchesi	2000	269
10	Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors Cell ·Hidehisa Takahashi, Tari Parmely, Shigeo Sato, Chieri Tomomori‐Sato, Charles A.S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin‐Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald Conaway, Joan Conaway	2011	264
11	A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16 Molecular and Cellular Biology ·Edwin R. Smith, Christelle Cayrou, Rong Huang, William S. Lane, Jacques Côté, John C. Lucchesi	2005	263
12	The super elongation complex (SEC) and MLL in development and disease Genes & Development ·Edwin R. Smith, Chengqi Lin, Ali Shilatifard	2011	256
13	Enhancer biology and enhanceropathies Nature Structural & Molecular Biology ·Edwin R. Smith, Ali Shilatifard	2014	220
14	Involvement of Human MOF in ATM Function Molecular and Cellular Biology ·Arun Gupta, Girdhar G. Sharma, Charles S. H. Young, Manjula Agarwal, Edwin R. Smith, Tanya T. Paull, John C. Lucchesi, Kum Kum Khanna, Thomas Ludwig, Tej K. Pandita	2005	185
15	The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes Molecular Cell ·Edwin R. Smith, Ali Shilatifard	2010	181
16	PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II Cell ·Fei Chen, Ashley R. Woodfin, Alessandro Gardini, Ryan Rickels, Stacy A. Marshall, Edwin R. Smith, Ramin Shiekhattar, Ali Shilatifard	2015	177
17	The COMPASS Family of H3K4 Methylases in Drosophila Molecular and Cellular Biology ·Man Mohan, Hans-Martin Herz, Edwin R. Smith, Ying Zhang, Jessica Jackson, Michael P. Washburn, Laurence Florens, Joel C. Eissenberg, Ali Shilatifard	2011	172
18	Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC) Genes & Development ·Chengqi Lin, Alexander S. Garrett, Bony De Kumar, Edwin R. Smith, Madelaine Gogol, Christopher Seidel, Robb Krumlauf, Ali Shilatifard	2011	149
19	Characterization of Human Cyclin-Dependent Kinase 12 (CDK12) and CDK13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and RNA Processing Molecular and Cellular Biology ·Kaiwei Liang, Xin Gao, Joshua M. Gilmore, Laurence Florens, Michael P. Washburn, Edwin R. Smith, Ali Shilatifard	2015	147
20	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability Nature Genetics ·Ryan Rickels, Hans-Martin Herz, Christie C. Sze, Kaixiang Cao, Marc A. Morgan, Clayton K. Collings, Maria Gause, Yoh-hei Takahashi, Lu Wang, Emily J. Rendleman, Stacy A. Marshall, Annika Krueger, Elizabeth T. Bartom, Andrea Piunti, Edwin R. Smith, Nebiyu Abshiru, Neil L. Kelleher, Dale Dorsett, Ali Shilatifard	2017	143

About Edwin R. Smith

Edwin R. Smith is a scholar working on Molecular Biology, Genetics, Plant Science, Radiology, Nuclear Medicine and Imaging and Hematology, having authored 57 papers that have together received 7.6k indexed citations. Recurring topics across this work include Genomics and Chromatin Dynamics (39 papers), Epigenetics and DNA Methylation (25 papers), Cancer-related gene regulation (19 papers), RNA Research and Splicing (15 papers), RNA modifications and cancer (10 papers), Protein Degradation and Inhibitors (7 papers), CRISPR and Genetic Engineering (4 papers) and Chromosomal and Genetic Variations (4 papers). The work is most often cited by research in Molecular Biology (6.9k citations), Aging (84 citations), Hematology (440 citations), Cancer Research (545 citations) and Virology (146 citations). Edwin R. Smith has collaborated with scholars based in United States, Canada and Spain. Frequent co-authors include Ali Shilatifard, Chengqi Lin, John C. Lucchesi, C. David Allis, Sukesh R. Bhaumik, Jung‐Shin Lee, Fei Chen, Michael P. Washburn, Laurence Florens and Xin Gao. Their work appears in journals such as Molecular and Cellular Biology, Genes & Development, Molecular Cell, Cell and Nature Structural & Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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