Frédéric Chédin

9.3k citations

58 papers · 6.0k indexed · 3 hit papers · h-index 41

Impact in

Molecular Biology top 1%
- DNA Repair Mechanisms
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- RNA modifications and cancer
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- Cancer-related gene regulation
Genetics top 1%

Papers in ⓘ

Molecular Biology 57
- DNA Repair Mechanisms 22
- Genomics and Chromatin Dynamics 20
- Epigenetics and DNA Methylation 20
- RNA and protein synthesis mechanisms 11
- DNA and Nucleic Acid Chemistry 11
- RNA modifications and cancer 10
- Cancer-related gene regulation 9
Genetics 19
- Bacterial Genetics and Biotechnology 10

Co-authors: Lionel A. Sanz (15 shared papers)Michael R. Lieber (2 shared papers)Paul A. Ginno (4 shared papers)Stella R. Hartono (19 shared papers)Ian Korf (3 shared papers)Paul C. Lott (2 shared papers)Chih‐Lin Hsieh (2 shared papers)Yoong Wearn Lim (3 shared papers)
Journals: Nucleic Acids Research (5 papers)eLife (5 papers)Journal of Biological Chemistry (4 papers)Proceedings of the National Academy of Sciences (4 papers)Molecular Microbiology (4 papers)
Partner nations: United States France Canada

In The Last Decade

Frédéric Chédin

56 papers receiving 6.0k citations

Hit Papers

align trajectories log scale

Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals 2016 · 395 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2016 Molecular Cell
2012 Molecular Cell
2003 Nature Immunology

Peers

Countries citing papers authored by Frédéric Chédin

Since Specialization

Citations

This map shows the geographic impact of Frédéric Chédin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frédéric Chédin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frédéric Chédin more than expected).

Fields of papers citing papers by Frédéric Chédin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frédéric Chédin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frédéric Chédin. The network helps show where Frédéric Chédin may publish in the future.

Co-authors

The 25 scholars most cited alongside Frédéric Chédin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frédéric Chédin Line = papers co-authored together Frédéric Chédin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 58 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters Molecular Cell ·Paul A. Ginno, Paul C. Lott, Holly C. Christensen, Ian Korf, Frédéric Chédin Hit paper breakdown →	2012	641
2	R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells Nature Immunology ·Kefei Yu, Frédéric Chédin, Chih-Lin Hsieh, Thomas E. Wilson, Michael R. Lieber Hit paper breakdown →	2003	601
3	Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals Molecular Cell ·Lionel A. Sanz, Stella R. Hartono, Yoong Wearn Lim, Sandra Steyaert, Aparna R. Rajpurkar, Paul A. Ginno, Xiaoqin Xu, Frédéric Chédin Hit paper breakdown →	2016	395
4	The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a Proceedings of the National Academy of Sciences ·Frédéric Chédin, Michael R. Lieber, Chih‐Lin Hsieh	2002	389
5	GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination Genome Research ·Paul A. Ginno, Yoong Wearn Lim, Paul C. Lott, Ian Korf, Frédéric Chédin	2013	275
6	Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage eLife ·Caroline Townsend Stork, M Bocek, Magdalena P. Crossley, Julie Sollier, Lionel A. Sanz, Frédéric Chédin, Tomek Swigut, Karlene A. Cimprich	2016	216
7	Arginine Methylation Facilitates the Recruitment of TOP3B to Chromatin to Prevent R Loop Accumulation Molecular Cell ·Yanzhong Yang, Kevin M. McBride, Sean C. Hensley, Yue Lu, Frédéric Chédin, Mark T. Bedford	2014	183
8	Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region PLoS Genetics ·Erick Loomis, Lionel A. Sanz, Frédéric Chédin, Paul J. Hagerman	2014	173
9	Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family Journal of Cellular Biochemistry ·Zhaoxia Chen, Jeffrey R. Mann, Chih‐Lin Hsieh, Arthur D. Riggs, Frédéric Chédin	2005	165
10	High-resolution, strand-specific R-loop mapping via S9.6-based DNA–RNA immunoprecipitation and high-throughput sequencing Nature Protocols ·Lionel A. Sanz, Frédéric Chédin	2019	153
11	Nascent Connections: R-Loops and Chromatin Patterning Trends in Genetics ·Frédéric Chédin	2016	152
12	Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein Journal of Biological Chemistry ·Nataliya Nady, Alexander Lemak, John R. Walker, G.V. Avvakumov, Michael S. Kareta, Mayada Achour, Sheng Xue, Shili Duan, Abdellah Allali‐Hassani, Xiaobing Zuo, Yun‐Xing Wang, Christian Bronner, Frédéric Chédin, C.H. Arrowsmith, Sirano Dhe‐Paganon	2011	152
13	Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome eLife ·Yoong Wearn Lim, Lionel A. Sanz, Xiaoqin Xu, Stella R. Hartono, Frédéric Chédin	2015	142
14	Reconstitution and Mechanism of the Stimulation of de Novo Methylation by Human DNMT3L Journal of Biological Chemistry ·Michael S. Kareta, Zaida M. Botello, Joshua Ennis, Christina Chou, Frédéric Chédin	2006	137
15	Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites Nature Communications ·Alexy Promonet, Ismaël Padioleau, Yaqun Liu, Lionel A. Sanz, Anna Biernacka, Anne-Lyne Schmitz, Magdalena Skrzypczak, Amélie Sarrazin, Clément Mettling, Maga Rowicka, Krzysztof Ginalski, Frédéric Chédin, Chun-Long Chen, Yea-Lih Lin, Philippe Pasero	2020	129
16	The DNMT3 Family of Mammalian De Novo DNA Methyltransferases Progress in molecular biology and translational science ·Frédéric Chédin	2011	128
17	R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation Proceedings of the National Academy of Sciences ·Weston T. Powell, Rochelle L. Coulson, Michael L. Gonzales, Florence K. Crary, Spencer S. Wong, Sarrita Adams, Robert A. Ach, Peter Tsang, N. Alice Yamada, Dag H. Yasui, Frédéric Chédin, Janine M. LaSalle	2013	126
18	DNA Topoisomerase I differentially modulates R-loops across the human genome Genome biology ·Stefano Giustino Manzo, Stella R. Hartono, Lionel A. Sanz, Jessica Marinello, Sara De Biasi, Andrea Cossarizza, Giovanni Capranico, Frédéric Chédin	2018	110
19	The Affinity of the S9.6 Antibody for Double-Stranded RNAs Impacts the Accurate Mapping of R-Loops in Fission Yeast Journal of Molecular Biology ·Stella R. Hartono, Amélie Malapert, Pénélope Legros, Pascal Bernard, Frédéric Chédin, Vincent Vanoosthuyse	2017	106
20	DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo PLoS Genetics ·Bethany L. Wienholz, Michael S. Kareta, Amir Moarefi, Catherine A. Gordon, Paul A. Ginno, Frédéric Chédin	2010	101

About Frédéric Chédin

Frédéric Chédin is a scholar working on Molecular Biology, Genetics, Epidemiology, Plant Science and Ecology, having authored 58 papers that have together received 6.0k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (22 papers), Genomics and Chromatin Dynamics (20 papers), Epigenetics and DNA Methylation (20 papers), RNA and protein synthesis mechanisms (11 papers), DNA and Nucleic Acid Chemistry (11 papers), Bacterial Genetics and Biotechnology (10 papers), RNA modifications and cancer (10 papers) and Cancer-related gene regulation (9 papers). The work is most often cited by research in Molecular Biology (5.5k citations), Genetics (1.2k citations), Cancer Research (426 citations), Aging (37 citations) and Immunology (417 citations). Frédéric Chédin has collaborated with scholars based in United States, France and Canada. Frequent co-authors include Lionel A. Sanz, Michael R. Lieber, Paul A. Ginno, Stella R. Hartono, Ian Korf, Paul C. Lott, Chih‐Lin Hsieh, Yoong Wearn Lim, Kefei Yu and Chih-Lin Hsieh. Their work appears in journals such as Nucleic Acids Research, eLife, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences and Molecular Microbiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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