Edward J. Cragoe

14.5k citations

346 papers · 12.4k indexed · 2 hit papers · h-index 56

Molecular Biology top 0.5%
Cellular and Molecular Neuroscience top 0.5%
Physiology top 1%
Cardiology and Cardiovascular Medicine top 1%
Surgery top 5%

Co-authors: Thomas R. Kleyman L Simchowitz L E Limbird Otto W. Woltersdorf John B. Bicking Christian Frelin A Franchi Gregory J. Kaczorowski
Topics: Ion Transport and Channel Regulation (115 papers)Ion channel regulation and function (100 papers)Neuroscience and Neuropharmacology Research (40 papers)
Cited by: Cellular and Molecular Neuroscience Molecular Biology Physiology
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: United States Canada Japan

In The Last Decade

Edward J. Cragoe

345 papers receiving 11.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Amiloride and its analogs as tools in the study of ion transport

1988 1.0k citations Edward J. Cragoe et al. profile →
Pyrazine Diuretics. II. N-Amidino-3-amino-5-substituted 6-Halopyrazinecarboxamides

1967 289 citations Edward J. Cragoe, Otto W. Woltersdorf et al. profile →

Peers

Countries citing papers authored by Edward J. Cragoe

Since Specialization

Citations

This map shows the geographic impact of Edward J. Cragoe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward J. Cragoe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward J. Cragoe more than expected).

Fields of papers citing papers by Edward J. Cragoe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward J. Cragoe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward J. Cragoe. The network helps show where Edward J. Cragoe may publish in the future.

Co-authorship network of co-authors of Edward J. Cragoe

This figure shows the co-authorship network connecting the top 25 collaborators of Edward J. Cragoe. A scholar is included among the top collaborators of Edward J. Cragoe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward J. Cragoe. Edward J. Cragoe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Control of hepatocyte DNA synthesis by intracellular pH and its role in the action of tumor promoters 2003 ·Journal of Cellular Physiology ·Chow H. Lee,Edward J. Cragoe,A. Edwards	24
2	Conductive cation transport in apical membrane vesicles prepared from fetal lung 1994 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Gregor K. Fyfe,Paul J. Kemp,Edward J. Cragoe,R. E. Olver	15
3	Sodium–Proton (Na+/H+) Exchange Inhibition Increases Blood Pressure in Spontaneously Hypertensive Rat 1994 ·The American Journal of the Medical Sciences ·Yiu-Fai Chen,Renhui Yang,Qingcheng Meng,Edward J. Cragoe,Suzanne Oparil	2
4	Amiloride inhibition of angiogenesis in vitro 1993 ·Journal of Experimental Zoology ·Mark C. Alliegro,Mary Anne Alliegro,Edward J. Cragoe,Bert M. Glaser	33
5	Pyrazine Compounds and the Measurement of Cytosolic Ca2+ 1993 ·Analytical Biochemistry ·(unknown),(unknown),Edward J. Cragoe,R Bose	7
6	Novel amiloride analog allosterically modulates the alpha 2-adrenergic receptor but does not inhibit Na+/H+ exchange. 1992 ·Molecular Pharmacology ·Amy L. Wilson,(unknown),Chandra Prakash,Edward J. Cragoe,(unknown),L E Limbird	9
7	Role of sodium in mediator release from human basophils 1992 ·Journal of Allergy and Clinical Immunology ·Thomas F. Smith,(unknown),(unknown),Michael H. Kutner,Edward J. Cragoe,Douglas C. Eaton	6
8	Inhibitory effect of local anesthetics on Na+/H+ antiporter in brush border membrane-reconstituted vesicles 1990 ·Life Sciences ·Sayumi Shibamoto,Takamitsu Hori,Makio Hayakawa,Mamoru Nango,Edward J. Cragoe,Naoto Oku,Fumiaki Ito	7
9	Species‐specific Mn²⁺/Mg²⁺ antiport from Mg²⁺‐loaded erythrocytes 1990 ·FEBS Letters ·Thomas Günther,Jürgen Vormann,Edward J. Cragoe	22
10	Effects of muscarinic, alpha-adrenergic, and substance P agonists and ionomycin on ion transport mechanisms in the rat parotid acinar cell. The dependence of ion transport on intracellular calcium. 1989 ·The Journal of General Physiology ·Stephen P. Soltoff,Michael McMillian,Lewis C. Cantley,Edward J. Cragoe,Barbara R. Talamo	73
11	Cytoplasmic alkalinization produced by the combination of anti-immunoglobulin antibody plus cytochalasin D in murine B lymphocytes 1989 ·Experimental Cell Research ·(unknown),Edward J. Cragoe,Thomas L. Rothstein	3
12	Treatment of tyramine-induced brain edema with anion transport inhibitor L-644, 711 1988 ·Life Sciences ·Bahjat A. Faraj,Edward J. Cragoe,(unknown),(unknown)	5
13	Paradoxical effects of amiloride analogs on protein phosphorylation and serotonin release induced by agonists in human platelets 1988 ·Biochemical and Biophysical Research Communications ·Ken‐ichi Yoshida,Ryoji Matoba,Edward J. Cragoe,Vivianne T. Nachmias	5
14	Intracellular pH changes of cultured bovine aortic endothelial cells in response to ATP addition 1988 ·Biochemical and Biophysical Research Communications ·Takanari Kitazono,Koichiro Takeshige,Edward J. Cragoe,Shigeki Minakami	46
15	Preparation of 6-125I-labeled amiloride derivatives 1988 ·Analytical Biochemistry ·Dan Cassel,Miriam Rotman,Edward J. Cragoe,Peter Igarashi	5
16	Activation of sodium‐proton exchange is not a prerequisite for Ca²⁺ mobilization and aggregation in human platelets 1987 ·FEBS Letters ·László Hunyady,Balázs Sarkadi,Edward J. Cragoe,András Spät,G. Gárdos	19
17	Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption. 1987 ·Journal of Clinical Investigation ·Patricia A. Preisig,Harlan E. Ives,Edward J. Cragoe,Robert J. Alpern,F. C. Rector	121
18	Improved Recovery from a Traumatic-Hypoxic Brain Injury in Cats by Intracisternal Injection of an Anion Transport Inhibitor 1987 ·PubMed ·Harold K. Kimelberg,Edward J. Cragoe,Louis R. Nelson,Alexander Popp,(unknown),(unknown),Otto W. Woltersdorf,(unknown)	25
19	Diuretic agents : based on a symposium sponsored by the ACS Division of Medicinal Chemistry at the 174th meeting of the American Chemical Society, Chicago, Illinois, August 29, 1977 1978 ·American Chemical Society eBooks ·Edward J. Cragoe	2
20	Inhibition of Dimethyltryptamine Biosynthesis by N,N'-Bis-(3-methyl-2-thiazolidinylidene)Succinamide (I) and 2-Imino-3-Methylthiazolidine (II) 1978 ·Molecular Pharmacology ·L Mandel,Joshua Rokach,C. S. ROONEY,Edward J. Cragoe	1

About Edward J. Cragoe

Edward J. Cragoe is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Physiology, having authored 346 papers that have together received 12.4k indexed citations. Recurring topics across this work include Ion Transport and Channel Regulation (115 papers), Ion channel regulation and function (100 papers) and Neuroscience and Neuropharmacology Research (40 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (2.8k citations), Molecular Biology (8.3k citations) and Physiology (437 citations). Edward J. Cragoe has collaborated with scholars based in United States, Canada and Japan. Frequent co-authors include Thomas R. Kleyman, L Simchowitz, L E Limbird, Otto W. Woltersdorf, John B. Bicking, Christian Frelin, A Franchi, Gregory J. Kaczorowski, James H. Jones and Qais Al‐Awqati. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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