Douglas R. Seals

44.1k total citations · 6 hit papers
440 papers, 34.2k citations indexed

About

Douglas R. Seals is a scholar working on Cardiology and Cardiovascular Medicine, Physiology and Complementary and alternative medicine. According to data from OpenAlex, Douglas R. Seals has authored 440 papers receiving a total of 34.2k indexed citations (citations by other indexed papers that have themselves been cited), including 260 papers in Cardiology and Cardiovascular Medicine, 191 papers in Physiology and 160 papers in Complementary and alternative medicine. Recurrent topics in Douglas R. Seals's work include Cardiovascular and exercise physiology (157 papers), Cardiovascular Health and Disease Prevention (124 papers) and Heart Rate Variability and Autonomic Control (116 papers). Douglas R. Seals is often cited by papers focused on Cardiovascular and exercise physiology (157 papers), Cardiovascular Health and Disease Prevention (124 papers) and Heart Rate Variability and Autonomic Control (116 papers). Douglas R. Seals collaborates with scholars based in United States, United Kingdom and Australia. Douglas R. Seals's co-authors include Hirofumi Tanaka, Kevin D. Monahan, Anthony J. Donato, Christopher A. DeSouza, Frank A. Dinenno, Iratxe Eskurza, Gary L. Pierce, Thomas J. LaRocca, P. P. Jones and Kristen Jablonski and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and JAMA.

In The Last Decade

Douglas R. Seals

430 papers receiving 33.2k citations

Hit Papers

Age-predicted maximal hea... 2000 2026 2008 2017 2001 2000 2000 2011 2018 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Age-predicted maximal heart rate revisited
    2001 2.6k citations Douglas R. Seals et al. profile →
  2. Aging, Habitual Exercise, and Dynamic Arterial Compliance
    2000 866 citations Frank A. Dinenno, Christopher A. DeSouza et al. Circulation profile →
  3. Regular Aerobic Exercise Prevents and Restores Age-Related Declines in Endothelium-Dependent Vasodilation in Healthy Men
    2000 699 citations Christopher A. DeSouza, Frank A. Dinenno et al. Circulation profile →
  4. Aging and vascular endothelial function in humans
    2011 538 citations Douglas R. Seals, Anthony J. Donato et al. profile →
  5. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
    2018 425 citations Michel Chonchol, Douglas R. Seals et al. profile →
  6. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults
    2018 331 citations Matthew J. Rossman, Jessica R. Santos‐Parker et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Douglas R. Seals United States 104 17.1k 11.1k 9.8k 3.7k 3.1k 440 34.2k
Michael J. Joyner United States 81 11.8k 0.7× 7.2k 0.6× 7.4k 0.8× 2.0k 0.5× 2.9k 0.9× 572 24.2k
Ross Arena United States 80 21.0k 1.2× 7.9k 0.7× 14.0k 1.4× 1.6k 0.5× 2.0k 0.6× 708 38.3k
Daniel J. Green Australia 84 14.1k 0.8× 6.2k 0.6× 6.9k 0.7× 1.7k 0.5× 1.4k 0.5× 529 26.4k
Ulrik Wisløff Norway 80 10.5k 0.6× 7.2k 0.6× 10.0k 1.0× 2.5k 0.7× 5.9k 1.9× 348 24.6k
Jerome L. Fleg United States 78 16.5k 1.0× 4.3k 0.4× 7.0k 0.7× 1.2k 0.3× 1.5k 0.5× 323 25.5k
Jonathan Myers United States 80 20.6k 1.2× 6.8k 0.6× 15.8k 1.6× 718 0.2× 1.7k 0.6× 621 31.4k
Bengt Saltin Denmark 122 12.8k 0.8× 19.5k 1.8× 19.2k 2.0× 7.1k 1.9× 14.8k 4.8× 496 52.0k
Timothy S. Church United States 85 7.5k 0.4× 14.3k 1.3× 7.0k 0.7× 1.2k 0.3× 1.7k 0.5× 308 28.8k
Robert Ross Canada 85 6.1k 0.4× 20.6k 1.9× 3.7k 0.4× 2.3k 0.6× 2.3k 0.7× 208 34.8k
Arthur S. Leon United States 67 6.6k 0.4× 14.9k 1.3× 5.2k 0.5× 1.6k 0.4× 2.5k 0.8× 253 33.8k

Countries citing papers authored by Douglas R. Seals

Since Specialization
Citations

This map shows the geographic impact of Douglas R. Seals's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas R. Seals with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas R. Seals more than expected).

Fields of papers citing papers by Douglas R. Seals

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas R. Seals. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas R. Seals. The network helps show where Douglas R. Seals may publish in the future.

Co-authorship network of co-authors of Douglas R. Seals

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas R. Seals. A scholar is included among the top collaborators of Douglas R. Seals based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas R. Seals. Douglas R. Seals is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chonchol, Michel, et al.. (2025). Oxidative stress suppresses internal carotid artery dilation to hypercapnia in healthy older adults. Journal of Applied Physiology. 138(2). 536–545.
2.
Mahoney, Sophia, David A. Hutton, Nicholas S. VanDongen, et al.. (2025). Cellular senescence mediates doxorubicin chemotherapy-induced vascular endothelial dysfunction: translational evidence of prevention with senolytic treatment. American Journal of Physiology-Heart and Circulatory Physiology. 329(6). H1672–H1683.
3.
Murray, Kevin, Katelyn R. Ludwig, Daniel H. Craighead, et al.. (2025). Preservation of Vascular Endothelial Function in Late-Onset Postmenopausal Women. Circulation Research. 136(5). 455–469. 2 indexed citations
4.
Seals, Douglas R., Christopher A. DeSouza, Roger M. Enoka, et al.. (2024). Is it the people or the place? The remarkable 30-year period of integrative physiology research in the Carlson Gymnasium at the University of Colorado Boulder. Journal of Applied Physiology. 137(1). 42–50. 1 indexed citations
5.
Wang, Wei, Douglas R. Seals, Michel Chonchol, et al.. (2023). Cerebrovascular pulsatility index is higher in chronic kidney disease. Physiological Reports. 11(1). e15561–e15561. 8 indexed citations
6.
Moreau, Kerrie L., Zachary S. Clayton, Lyndsey E. DuBose, Ryan Rosenberry, & Douglas R. Seals. (2023). Effects of regular exercise on vascular function with aging: Does sex matter?. American Journal of Physiology-Heart and Circulatory Physiology. 326(1). H123–H137. 25 indexed citations
7.
Craighead, Daniel H., Matthew J. Rossman, Brian P. Ziemba, et al.. (2021). Time‐Efficient Inspiratory Muscle Strength Training Lowers Blood Pressure and Improves Endothelial Function, NO Bioavailability, and Oxidative Stress in Midlife/Older Adults With Above‐Normal Blood Pressure. Journal of the American Heart Association. 10(13). e020980–e020980. 75 indexed citations
8.
Wahl, Devin, et al.. (2020). Healthy Aging Interventions Reduce Repetitive Element Transcripts. The Journals of Gerontology Series A. 76(5). 805–810. 23 indexed citations
9.
Rossman, Matthew J., Rachel A. Gioscia‐Ryan, Jessica R. Santos‐Parker, et al.. (2020). Inorganic Nitrite Supplementation Improves Endothelial Function with Aging: Translational Evidence for Suppression of Mitochondria-Derived Oxidative Stress. Journal of the American Society of Nephrology. 31(10S). 40–40. 1 indexed citations
10.
Ozemek, Cemal, Kerry L. Hildreth, Patrick J. Blatchford, et al.. (2020). Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women. Journal of Applied Physiology. 128(4). 739–747. 27 indexed citations
11.
Lesniewski, Lisa A., Douglas R. Seals, Ashley E. Walker, et al.. (2016). Dietary rapamycin supplementation reverses age‐related vascular dysfunction and oxidative stress, while modulating nutrient‐sensing, cell cycle, and senescence pathways. Aging Cell. 16(1). 17–26. 137 indexed citations
12.
Gavin, Kathleen M., Douglas R. Seals, Annemarie Silver, & Kerrie L. Moreau. (2009). Vascular Endothelial Estrogen Receptor α Is Modulated by Estrogen Status and Related to Endothelial Function and Endothelial Nitric Oxide Synthase in Healthy Women. The Journal of Clinical Endocrinology & Metabolism. 94(9). 3513–3520. 161 indexed citations
13.
Donato, Anthony J., Gary L. Pierce, Lisa A. Lesniewski, & Douglas R. Seals. (2009). Role of NFκB in age-related vascular endothelial dysfunction in humans. Aging. 1(8). 678–680. 60 indexed citations
14.
Pierce, Gary L., Lisa A. Lesniewski, Brooke R. Lawson, Stacy D. Beske, & Douglas R. Seals. (2008). Abstract 5459: Vascular Endothelial Nuclear Factor-{kappa}B Contributes to Endothelial Dysfunction Via Oxidative Stress in Middle-Aged and Older Overweight/Obese Humans. Circulation. 118. 1 indexed citations
15.
Gates, Phillip E. & Douglas R. Seals. (2006). Decline in large elastic artery compliance with age: a therapeutic target for habitual exercise. British Journal of Sports Medicine. 40(11). 897–899. 18 indexed citations
16.
Eskurza, Iratxe, et al.. (2006). Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium‐dependent dilatation with ageing. The Journal of Physiology. 571(3). 661–668. 82 indexed citations
17.
Seals, Douglas R. & Frank A. Dinenno. (2004). Collateral damage: cardiovascular consequences of chronic sympathetic activation with human aging. American Journal of Physiology-Heart and Circulatory Physiology. 287(5). H1895–H1905. 110 indexed citations
18.
DeSouza, Christopher A., et al.. (2001). Total and regional body composition across age in healthy Hispanic and white women of similar socioeconomic status. American Journal of Clinical Nutrition. 73(1). 13–18. 55 indexed citations
19.
Jones, P. P., et al.. (1997). The influence of total body and abdominal fatness on sympathetic nerve activity in older vs young adults. The FASEB Journal. 11(3). 254. 2 indexed citations
20.
Seals, Douglas R., et al.. (1988). Left ventricular dysfunction after prolonged strenuous exercise in healthy subjects. The American Journal of Cardiology. 61(11). 875–879. 62 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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