Simon Melov

22.4k total citations · 7 hit papers
124 papers, 15.1k citations indexed

About

Simon Melov is a scholar working on Molecular Biology, Physiology and Aging. According to data from OpenAlex, Simon Melov has authored 124 papers receiving a total of 15.1k indexed citations (citations by other indexed papers that have themselves been cited), including 71 papers in Molecular Biology, 48 papers in Physiology and 39 papers in Aging. Recurrent topics in Simon Melov's work include Genetics, Aging, and Longevity in Model Organisms (39 papers), Mitochondrial Function and Pathology (32 papers) and Telomeres, Telomerase, and Senescence (13 papers). Simon Melov is often cited by papers focused on Genetics, Aging, and Longevity in Model Organisms (39 papers), Mitochondrial Function and Pathology (32 papers) and Telomeres, Telomerase, and Senescence (13 papers). Simon Melov collaborates with scholars based in United States, Canada and Australia. Simon Melov's co-authors include Judith Campisi, Douglas C. Wallace, Gordon J. Lithgow, Pankaj Kapahi, Alan Hubbard, James M. Flynn, Tamara R. Golden, Mark A. Tarnopolsky, Thomas E. Johnson and Enrique Samper and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Simon Melov

118 papers receiving 14.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

1995 1.4k citations Simon Melov, Douglas C. Wallace et al. profile →
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

2003 885 citations Enrique Samper, Simon Melov et al. profile →
From discoveries in ageing research to therapeutics for healthy ageing

2019 877 citations Judith Campisi, Pankaj Kapahi et al. Nature profile →
Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

2000 719 citations Simon Melov, Douglas C. Wallace et al. profile →
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress.

1995 711 citations Gordon J. Lithgow, Simon Melov et al. profile →
Unmasking Transcriptional Heterogeneity in Senescent Cells

2017 616 citations Simon Melov, Judith Campisi et al. profile →
Mitochondrial disease in mouse results in increased oxidative stress

1999 523 citations Simon Melov, Douglas C. Wallace et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Simon Melov United States	61	8.3k	5.0k	3.3k	1.2k	1.1k	124	15.1k
Holly Van Remmen United States	68	12.6k 1.5×	7.1k 1.4×	3.0k 0.9×	1.1k 0.9×	1.4k 1.3×	220	20.5k
Michael Ristow Germany	56	6.6k 0.8×	5.1k 1.0×	2.2k 0.7×	1.0k 0.9×	1.0k 0.9×	162	15.7k
Pankaj Kapahi United States	49	4.8k 0.6×	2.8k 0.5×	3.8k 1.1×	1.1k 1.0×	559 0.5×	107	11.1k
Randy Strong United States	50	5.9k 0.7×	5.1k 1.0×	4.1k 1.3×	1.8k 1.6×	825 0.8×	130	13.8k
Reinald Pamplona Spain	64	6.6k 0.8×	4.9k 1.0×	1.7k 0.5×	717 0.6×	857 0.8×	285	13.3k
Riekelt H. Houtkooper Netherlands	60	9.1k 1.1×	4.7k 0.9×	1.5k 0.5×	622 0.5×	1.1k 1.0×	193	16.9k
George M. Martin United States	64	11.3k 1.4×	6.6k 1.3×	2.3k 0.7×	1.7k 1.5×	1.2k 1.1×	316	17.9k
Matt Kaeberlein United States	65	12.7k 1.5×	6.0k 1.2×	9.0k 2.7×	892 0.8×	1.3k 1.2×	226	21.8k
Siegfried Hekimi Canada	49	6.7k 0.8×	2.6k 0.5×	5.5k 1.7×	643 0.6×	715 0.7×	114	11.9k
Carles Cantó Switzerland	47	7.4k 0.9×	6.3k 1.2×	1.0k 0.3×	585 0.5×	915 0.8×	72	15.9k

Countries citing papers authored by Simon Melov

Since Specialization

Citations

This map shows the geographic impact of Simon Melov's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon Melov with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon Melov more than expected).

Fields of papers citing papers by Simon Melov

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon Melov. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon Melov. The network helps show where Simon Melov may publish in the future.

Co-authorship network of co-authors of Simon Melov

This figure shows the co-authorship network connecting the top 25 collaborators of Simon Melov. A scholar is included among the top collaborators of Simon Melov based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Simon Melov. Simon Melov is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Mahoney, Sophia, David A. Hutton, Nicholas S. VanDongen, et al.. (2025). Cellular senescence mediates doxorubicin chemotherapy-induced vascular endothelial dysfunction: translational evidence of prevention with senolytic treatment. American Journal of Physiology-Heart and Circulatory Physiology. 329(6). H1672–H1683.

Bose, Neelanjan, Martín Valdearcos, Parminder Singh, et al.. (2025). Glycation-lowering compounds inhibit ghrelin signaling to reduce food intake, lower insulin resistance, and extend lifespan. Cell Reports. 44(10). 116422–116422.

Goncharova, Elena A., Edna Nyangau, Mahalakshmi Shankaran, et al.. (2023). The D₃‐creatine dilution method non‐invasively measures muscle mass in mice. Aging Cell. 22(8). e13897–e13897. 3 indexed citations

Hodge, Brian A., Subhash D. Katewa, Ting Lian, et al.. (2022). Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster. Nature Communications. 13(1). 3156–3156. 22 indexed citations

Wong, Hoi Shan, Vojtěch Mezera, Pratiksha Dighe, et al.. (2021). Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice. Free Radical Biology and Medicine. 164. 223–232. 13 indexed citations

Campisi, Judith, Pankaj Kapahi, Gordon J. Lithgow, et al.. (2019). From discoveries in ageing research to therapeutics for healthy ageing. Nature. 571(7764). 183–192. 877 indexed citations breakdown →

Myagmar, Bat‐Erdene, James M. Flynn, Patrick M. Cowley, et al.. (2017). Adrenergic Receptors in Individual Ventricular Myocytes. Circulation Research. 120(7). 1103–1115. 91 indexed citations

Fontana, Luigi, Brian K. Kennedy, Valter D. Longo, Douglas R. Seals, & Simon Melov. (2014). Medical research: Treat ageing. Nature. 511(7510). 405–407. 191 indexed citations

Flynn, James M. & Simon Melov. (2013). SOD2 in mitochondrial dysfunction and neurodegeneration. Free Radical Biology and Medicine. 62. 4–12. 280 indexed citations

10.

An, Mahru C., Ningzhe Zhang, Gary K. Scott, et al.. (2012). Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells. Cell stem cell. 11(2). 253–263. 284 indexed citations

11.

Campisi, Judith, Julie K. Andersen, Pankaj Kapahi, & Simon Melov. (2011). Cellular senescence: A link between cancer and age-related degenerative disease?. Seminars in Cancer Biology. 21(6). 354–9. 322 indexed citations

12.

Rogers, Aric N., Di Chen, Gawain McColl, et al.. (2011). Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans. Cell Metabolism. 14(1). 55–66. 103 indexed citations

13.

McColl, Gawain, Aric N. Rogers, Silvestre Alavez, et al.. (2010). Insulin-like Signaling Determines Survival during Stress via Posttranscriptional Mechanisms in C. elegans. Cell Metabolism. 12(3). 260–272. 87 indexed citations

14.

Bell, Russell, Alan Hubbard, Rakesh Chettier, et al.. (2009). A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species. PLoS Genetics. 5(3). e1000414–e1000414. 94 indexed citations

15.

Abadi, Arkan, Elisa I. Glover, Robert J. Isfort, et al.. (2009). Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women. PLoS ONE. 4(8). e6518–e6518. 149 indexed citations

16.

Golden, Tamara R., et al.. (2007). Dramatic age‐related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans. Aging Cell. 6(2). 179–188. 45 indexed citations

17.

Puglielli, Luigi, Avi L. Friedlich, Kenneth D.R. Setchell, et al.. (2005). Alzheimer disease β-amyloid activity mimics cholesterol oxidase. Journal of Clinical Investigation. 115(9). 2556–2563. 116 indexed citations

18.

Lopez, Mary F., Alvydas Mikulskis, Eva Golenko, et al.. (2004). Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples. Electrophoresis. 25(15). 2557–2563. 5 indexed citations

19.

Golden, Tamara R. & Simon Melov. (2001). Mitochondrial DNA mutations, oxidative stress, and aging. Mechanisms of Ageing and Development. 122(14). 1577–1589. 91 indexed citations

20.

Melov, Simon, John M. Shoffner, A. Kaufman, & Douglas C. Wallace. (1995). Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle. Nucleic Acids Research. 23(20). 4122–4126. 222 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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