Douglas R. Lowy

50.2k total citations · 13 hit papers
339 papers, 37.9k citations indexed

About

Douglas R. Lowy is a scholar working on Epidemiology, Molecular Biology and Genetics. According to data from OpenAlex, Douglas R. Lowy has authored 339 papers receiving a total of 37.9k indexed citations (citations by other indexed papers that have themselves been cited), including 145 papers in Epidemiology, 133 papers in Molecular Biology and 98 papers in Genetics. Recurrent topics in Douglas R. Lowy's work include Cervical Cancer and HPV Research (119 papers), Virus-based gene therapy research (95 papers) and Hepatitis B Virus Studies (62 papers). Douglas R. Lowy is often cited by papers focused on Cervical Cancer and HPV Research (119 papers), Virus-based gene therapy research (95 papers) and Hepatitis B Virus Studies (62 papers). Douglas R. Lowy collaborates with scholars based in United States, France and Costa Rica. Douglas R. Lowy's co-authors include John T. Schiller, Berthe M. Willumsen, Alex G. Papageorge, Edward M. Scolnick, William C. Vass, Patricia M. Day, N L Hubbert, Esther H. Chang, Reinhard Kirnbauer and Christopher B. Buck and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Douglas R. Lowy

332 papers receiving 35.4k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mechanism of activation of a human oncogene

1982 1.1k citations Alex G. Papageorge, Douglas R. Lowy et al. profile →
The Effect of Advances in Lung-Cancer Treatment on Population Mortality

2020 1.1k citations Douglas R. Lowy et al. profile →
Toward a Shared Vision for Cancer Genomic Data

2016 1.1k citations Douglas R. Lowy et al. profile →
FUNCTION AND REGULATION OF RAS

1993 980 citations Douglas R. Lowy, Berthe M. Willumsen profile →
Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic.

1992 883 citations Douglas R. Lowy, John T. Schiller et al. profile →
HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes.

1989 772 citations Douglas R. Lowy, John T. Schiller et al. profile →
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

1981 644 citations Douglas R. Lowy et al. profile →
Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles

1993 504 citations Douglas R. Lowy, John T. Schiller et al. profile →
The p21 ras C-terminus is required for transformation and membrane association

1984 501 citations Berthe M. Willumsen, Alex G. Papageorge et al. profile →
Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 500 citations Douglas R. Lowy et al. profile →
Murine Leukemia Virus: High-Frequency Activation in vitro by 5-Iododeoxyuridine and 5-Bromodeoxyuridine

1971 488 citations Douglas R. Lowy et al. profile →
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1992 482 citations Alex G. Papageorge, William C. Vass et al. profile →
Reduced Prevalence of Oral Human Papillomavirus (HPV) 4 Years after Bivalent HPV Vaccination in a Randomized Clinical Trial in Costa Rica

2013 350 citations Rolando Herrero, Wim Quint et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Douglas R. Lowy United States	114	15.9k	14.7k	8.5k	8.1k	7.8k	339	37.9k
Peter M. Howley United States	101	19.4k 1.2×	17.9k 1.2×	10.4k 1.2×	7.0k 0.9×	15.8k 2.0×	244	40.4k
Herbert W. Virgin United States	98	12.7k 0.8×	16.0k 1.1×	4.7k 0.6×	10.5k 1.3×	6.0k 0.8×	258	38.7k
John T. Schiller United States	97	5.7k 0.4×	18.7k 1.3×	5.4k 0.6×	8.4k 1.0×	4.1k 0.5×	292	27.8k
Hilary Koprowski United States	105	16.7k 1.1×	8.1k 0.6×	5.4k 0.6×	10.1k 1.2×	6.5k 0.8×	811	41.4k
Karl Münger United States	75	9.6k 0.6×	11.5k 0.8×	4.5k 0.5×	3.7k 0.5×	9.4k 1.2×	190	23.0k
Stuart A. Aaronson United States	107	27.9k 1.8×	3.4k 0.2×	9.3k 1.1×	6.4k 0.8×	12.2k 1.6×	438	45.8k
Charles M. Rice United States	140	16.8k 1.1×	27.4k 1.9×	3.7k 0.4×	13.1k 1.6×	3.4k 0.4×	476	67.0k
Harald zur Hausen Germany	79	8.0k 0.5×	20.1k 1.4×	5.6k 0.7×	5.1k 0.6×	10.9k 1.4×	261	32.2k
Hidde L. Ploegh United States	133	30.3k 1.9×	11.7k 0.8×	4.5k 0.5×	25.9k 3.2×	9.9k 1.3×	607	62.0k
James M. Wilson United States	136	37.1k 2.3×	7.3k 0.5×	34.5k 4.1×	6.8k 0.8×	8.6k 1.1×	900	64.0k

Countries citing papers authored by Douglas R. Lowy

Since Specialization

Citations

This map shows the geographic impact of Douglas R. Lowy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas R. Lowy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas R. Lowy more than expected).

Fields of papers citing papers by Douglas R. Lowy

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas R. Lowy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas R. Lowy. The network helps show where Douglas R. Lowy may publish in the future.

Co-authorship network of co-authors of Douglas R. Lowy

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas R. Lowy. A scholar is included among the top collaborators of Douglas R. Lowy based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas R. Lowy. Douglas R. Lowy is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sierra, Mónica S., Peter Dull, Rolando Herrero, et al.. (2025). Human papillomavirus type 16 and 18 viral clearance and progression to precancer among women aged 18–25 years enrolled in the Costa Rica HPV prophylactic vaccine trial (CVT). Vaccine. 50. 126841–126841.

Halpern, Michael T., Benmei Liu, Douglas R. Lowy, et al.. (2024). The Annual Cost of Cancer Screening in the United States. Annals of Internal Medicine. 177(9). 1170–1178. 12 indexed citations

Hu, Shangying, Aimée R. Kreimer, Carolina Porras, et al.. (2022). Performance of Cervical Screening a Decade Following HPV Vaccination: The Costa Rica Vaccine Trial. JNCI Journal of the National Cancer Institute. 114(9). 1253–1261. 3 indexed citations

Tripathi, Brajendra K., Xiaolan Qian, Dunrui Wang, et al.. (2021). Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein. Nature Communications. 12(1). 6941–6941. 12 indexed citations

Wang, Dunrui, Xiaolan Qian, Beatriz Sánchez‐Solana, et al.. (2020). Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function. Cancer Research. 80(17). 3568–3579. 15 indexed citations

Kreimer, Aimée R., Rolando Herrero, Joshua N. Sampson, et al.. (2018). Evidence for single-dose protection by the bivalent HPV vaccine—Review of the Costa Rica HPV vaccine trial and future research studies. Vaccine. 36(32). 4774–4782. 97 indexed citations

Robbins, Hilary A., Troy J. Kemp, Carolina Porras, et al.. (2014). Comparison of Antibody Responses to Human Papillomavirus Vaccination as Measured by Three Assays. Frontiers in Oncology. 3. 328–328. 21 indexed citations

Safaeian, Mahboobeh, Carolina Porras, Yuanji Pan, et al.. (2013). Durable Antibody Responses Following One Dose of the Bivalent Human Papillomavirus L1 Virus-Like Particle Vaccine in the Costa Rica Vaccine Trial. Cancer Prevention Research. 6(11). 1242–1250. 159 indexed citations

Qian, Xiaolan, Marian E. Durkin, Dunrui Wang, et al.. (2012). Inactivation of the Dlc1 Gene Cooperates with Downregulation of p15INK4b and p16Ink4a , Leading to Neoplastic Transformation and Poor Prognosis in Human Cancer. Cancer Research. 72(22). 5900–5911. 25 indexed citations

10.

Du, Xiaoli, Xiaolan Qian, Alex G. Papageorge, et al.. (2012). Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells. Cancer Research. 72(17). 4405–4416. 42 indexed citations

11.

Mitsunaga, Makoto, Nobuyuki Kosaka, Rhonda C. Kines, et al.. (2011). In Vivo Longitudinal Imaging of Experimental Human Papillomavirus Infection in Mice with a Multicolor Fluorescence Mini-Endoscopy System. Cancer Prevention Research. 4(5). 767–773. 14 indexed citations

12.

Herrero, Rolando, Sholom Wacholder, Ana Cecilia Rodríguez, et al.. (2011). Prevention of Persistent Human Papillomavirus Infection by an HPV16/18 Vaccine: A Community-Based Randomized Clinical Trial in Guanacaste, Costa Rica. Cancer Discovery. 1(5). 408–419. 116 indexed citations

13.

Hildesheim, Allan, Rolando Herrero, Sholom Wacholder, et al.. (2007). Effect of Human Papillomavirus 16/18 L1 Viruslike Particle Vaccine Among Young Women With Preexisting Infection. JAMA. 298(7). 743–743. 463 indexed citations

14.

Lowy, Douglas R., Jeffrey E. DeClue, Ke Zhang, et al.. (2007). Cell Transformation by ras and Regulation of its Protein Product. Novartis Foundation symposium. 176. 67–84. 1 indexed citations

15.

Durkin, Marian E., Bao‐Zhu Yuan, Xiaoling Zhou, et al.. (2007). DLC‐1:a Rho GTPase‐activating protein and tumour suppressor. Journal of Cellular and Molecular Medicine. 11(5). 1185–1207. 155 indexed citations

16.

Lowy, Douglas R.. (2006). Prophylactic human papillomavirus vaccines. Journal of Clinical Investigation. 116(5). 1167–1173. 288 indexed citations

17.

Melillo, Rosa Marina, Kristian Helin, Douglas R. Lowy, & John T. Schiller. (1994). Positive and Negative Regulation of Cell Proliferation by E2F-1: Influence of Protein Level and Human Papillomavirus Oncoproteins. Molecular and Cellular Biology. 14(12). 8241–8249. 34 indexed citations

18.

Willumsen, Berthe M., William C. Vass, Thierry Velu, et al.. (1991). The Bovine Papillomavirus E5 Oncogene Can Cooperate with ras: Identification of p21 Amino Acids Critical for Transformation by c-ras ^H but Not v-ras ^H. Molecular and Cellular Biology. 11(12). 6026–6033. 19 indexed citations

19.

Collin, Carlos, et al.. (1990). Early regulation of membrane excitability by ras oncogene proteins. Biophysical Journal. 58(3). 785–790. 13 indexed citations

20.

Stone, James C., William C. Vass, Berthe M. Willumsen, & Douglas R. Lowy. (1988). p21- ras Effector Domain Mutants Constructed by "Cassette" Mutagenesis. Molecular and Cellular Biology. 8(8). 3565–3569. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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