Diether Lambrechts

69.4k total citations · 5 hit papers
296 papers, 14.4k citations indexed

About

Diether Lambrechts is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Diether Lambrechts has authored 296 papers receiving a total of 14.4k indexed citations (citations by other indexed papers that have themselves been cited), including 120 papers in Molecular Biology, 113 papers in Oncology and 81 papers in Cancer Research. Recurrent topics in Diether Lambrechts's work include Cancer Genomics and Diagnostics (51 papers), Ovarian cancer diagnosis and treatment (26 papers) and Epigenetics and DNA Methylation (23 papers). Diether Lambrechts is often cited by papers focused on Cancer Genomics and Diagnostics (51 papers), Ovarian cancer diagnosis and treatment (26 papers) and Epigenetics and DNA Methylation (23 papers). Diether Lambrechts collaborates with scholars based in Belgium, United States and Netherlands. Diether Lambrechts's co-authors include Peter Carmeliet, Bram Boeckx, Erik Storkebaum, Bart Claes, Massimiliano Mazzone, Bernard Thienpont, Stein Aerts, Ian Buysschaert, Serena Zacchigna and Joke Reumers and has published in prestigious journals such as Nature, New England Journal of Medicine and Cell.

In The Last Decade

Diether Lambrechts

278 papers receiving 14.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Phenotype molding of stromal cells in the lung tumor microenvironment

2018 1.0k citations Diether Lambrechts, Els Wauters et al. Nature Medicine profile →
Gene prioritization through genomic data fusion

2006 661 citations Stein Aerts, Diether Lambrechts et al. profile →
Tumour hypoxia causes DNA hypermethylation by reducing TET activity

2016 459 citations Bernard Thienpont, Bram Boeckx et al. profile →
A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer

2021 442 citations Ayse Bassez, Ingrid Arijs et al. Nature Medicine profile →
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

2014 388 citations Matthieu Moisse, Diether Lambrechts et al. Nature Communications profile →

Peers

Countries citing papers authored by Diether Lambrechts

Since Specialization

Citations

This map shows the geographic impact of Diether Lambrechts's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Diether Lambrechts with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Diether Lambrechts more than expected).

Fields of papers citing papers by Diether Lambrechts

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Diether Lambrechts. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Diether Lambrechts. The network helps show where Diether Lambrechts may publish in the future.

Co-authorship network of co-authors of Diether Lambrechts

This figure shows the co-authorship network connecting the top 25 collaborators of Diether Lambrechts. A scholar is included among the top collaborators of Diether Lambrechts based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Diether Lambrechts. Diether Lambrechts is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Single-cell transcriptome atlas of male mouse pituitary across postnatal life highlighting its stem cell landscape 2025 ·iScience ·(unknown), (unknown), (unknown), (unknown), Florian Hermans, Diether Lambrechts, Hugo Vankelecom	2
2	Single-cell profiling in ovarian germ cell and sex cord-stromal tumours 2025 ·British Journal of Cancer ·(unknown), Anne‐Sophie Van Rompuy, (unknown), Gloria Marquina, (unknown), Siel Olbrecht, (unknown), Thaïs Baert, Toon Van Gorp, I. Vergote, Diether Lambrechts, Els Van Nieuwenhuysen	0
3	2MO Expression levels of immune checkpoint markers (IC) in hormone receptor-positive/HER2-negative (HR+/HER2-) metastatic breast cancer (BC) 2023 ·ESMO Open ·(unknown), (unknown), Maxim De Schepper, Tatjana Geukens, Karen Van Baelen, Marion Maetens, (unknown), (unknown), Bram Boeckx, (unknown), Kevin Punie, Patrick Neven, Hans Wildiers, W. Van den Bogaert, Elia Biganzoli, Diether Lambrechts, Gianluca Floris, François Richard, Christine Desmedt	1
4	PD-1- CD45RA+ effector-memory CD8 T cells and CXCL10+ macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma 2023 ·Nature Communications ·Sarah Cappuyns, (unknown), Vincent Vandecaveye, Bram Boeckx, Rogier Schepers, Thomas Van Brussel, Ingrid Arijs, (unknown), Ayse Bassez, Francesca Lodi, Joris Jaekers, (unknown), Baki Topal, Orian Bricard, Junbin Qian, Eric Van Cutsem, Chris Verslype, Diether Lambrechts, Jeroen Dekervel	33
5	2022-RA-638-ESGO Pembrolizumab with multimodal immunomodulation in chemotherapy-pretreated cervical, endometrial, and uterine cancer: the PRIMMO phase II trial 2022 ·International Journal of Gynecological Cancer ·Emiel A. De Jaeghere, Sandra Tuyaerts, (unknown), Ann Belmans, Kris Bogaerts, (unknown), Peter Vuylsteke, Stéphanie Henry, Xuan Bich Trinh, Peter A. van Dam, Sandrine Aspeslagh, (unknown), Eline Naert, Diether Lambrechts, An Hendrix, Olivier De Wever, Koen Van de Vijver, Frédéric Amant, Katrien Vandecasteele, Hannelore Denys	0
6	2022-RA-1136-ESGO A single-cell map of rare ovarian cancer 2022 ·International Journal of Gynecological Cancer ·(unknown), Pieter Busschaert, Siel Olbrecht, Liselore Loverix, Francesca Lodi, Thaïs Baert, Toon Van Gorp, Anne‐Sophie Van Rompuy, Ignace Vergote, Diether Lambrechts, Els Van Nieuwenhuysen	2
7	Organoids from human tooth showing epithelial stemness phenotype and differentiation potential 2022 ·Cellular and Molecular Life Sciences ·(unknown), Florian Hermans, Joel Chappell, Hiroto Kobayashi, Diether Lambrechts, Ivo Lambrichts, Annelies Bronckaers, Hugo Vankelecom	30
8	CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation 2022 ·Cell Reports ·Juan Fernández-García, Fabien Franco, Sweta Parik, Patricia Altea‐Manzano, (unknown), Dorien Broekaert, Joke Van Elsen, Giusy Di Conza, Ines Vermeire, (unknown), Mélanie Planque, Thomas Van Brussel, Rogier Schepers, Elodie Modave, Tobias K. Karakach, Peter Carmeliet, Diether Lambrechts, Ping‐Chih Ho, Sarah‐Maria Fendt	21
9	BCL9 regulates CD226 and CD96 checkpoints in CD8+ T cells to improve PD-1 response in cancer 2021 ·Signal Transduction and Targeted Therapy ·Mei Feng, (unknown), Yan Zhou, (unknown), (unknown), Shenglin Mei, Yuanyuan Zhu, Chenglong Liu, (unknown), Huiyu Li, Cao Xie, Joy Q. Jin, Jibin Dong, Dehua Yang, Ker Yu, Jun Qian, Diether Lambrechts, Ming‐Wei Wang, Di Zhu	28
10	Molecular Biomarkers of Response to Eribulin in Patients with Leiomyosarcoma 2021 ·Clinical Cancer Research ·Agnieszka Woźniak, Bram Boeckx, Elodie Modave, (unknown), Diether Lambrechts, Bruce A. Littlefield, Patrick Schöffski	8
11	Cytotoxic T-lymphocytes and dendritic cells driving the inflammatory micro-environment of Peyronie’s disease 2020 ·European Urology Open Science ·Uroš Milenković, Bram Boeckx, Diether Lambrechts, (unknown), (unknown), Dirk De Ridder, Maarten Albersen	0
12	Characterization of Stromal Tumor-infiltrating Lymphocytes and Genomic Alterations in Metastatic Lobular Breast Cancer 2020 ·Clinical Cancer Research ·François Richard, Samira Majjaj, David Venet, Françoise Rothé, (unknown), Bram Boeckx, Caterina Marchiò, Florian Clatot, François Bertucci, Odette Mariani, Christine Galant, Gert Van den Eynden, Roberto Salgado, Elia Biganzoli, Diether Lambrechts, Anne Vincent‐Salomon, Giancarlo Pruneri, Denis Larsimont, Christos Sotiriou, Christine Desmedt	19
13	Polymorphisms in the Von Hippel–Lindau Gene Are Associated With Overall Survival in Metastatic Clear-Cell Renal-Cell Carcinoma Patients Treated With VEGFR Tyrosine Kinase Inhibitors 2018 ·Clinical Genitourinary Cancer ·Annelies Verbiest, Diether Lambrechts, Thomas Van Brussel, Gabrielle Couchy, Agnieszka Woźniak, Arnaud Méjean, Evelyne Lerut, Stéphane Oudard, Virginie Verkarre, Sylvie Job, Aurélien de Reyniès, Jean‐Pascal Machiels, Jean‐Jacques Patard, Jessica Zucman‐Rossi, Benoit Beuselinck	8
14	Phenotype molding of stromal cells in the lung tumor microenvironment breakdown → 2018 ·Nature Medicine ·Diether Lambrechts, Els Wauters, Bram Boeckx, Sara Aibar, David Nittner, Oliver T. Burton, Ayse Bassez, Herbert Decaluwé, Andreas Pircher, Kathleen Van den Eynde, Birgit Weynand, Erik Verbeken, Paul De Leyn, Adrian Liston, Johan Vansteenkiste, Peter Carmeliet, Stein Aerts, Bernard Thienpont	1037
15	Global and gene-specific DNA methylation effects of different asbestos fibres on human bronchial epithelial cells 2018 ·Environment International ·Deniz Öner, Manosij Ghosh, Matthieu Moisse, Radu Corneliu Duca, (unknown), Jeroen Vanoirbeek, Diether Lambrechts, Lode Godderis, Peter Hoet	8
16	Amplification of 1q32.1 Refines the Molecular Classification of Endometrial Carcinoma 2017 ·Clinical Cancer Research ·Jeroen Depreeuw, Ellen Stelloo, Elisabeth M. Osse, Carien L. Creutzberg, Remi A. Nout, Matthieu Moisse, (unknown), Michael Dewaele, Karen Willekens, Jean‐Christophe Marine, Xavier Matías‐Guiu, Frédéric Amant, Diether Lambrechts, Tjalling Bosse	35
17	Chromosomal Instability in Cell-Free DNA as a Highly Specific Biomarker for Detection of Ovarian Cancer in Women with Adnexal Masses 2016 ·Clinical Cancer Research ·Adriaan Vanderstichele, Pieter Busschaert, Dominiek Smeets, C. Landolfo, Els Van Nieuwenhuysen, Karin Leunen, Patrick Neven, Frédéric Amant, Sven� Mahner, Elena Ioana Braicu, (unknown), An Coosemans, D. Timmerman, Diether Lambrechts, Ignace Vergote	78
18	Chromosomal instability in cell-free DNA as a highly specific biomarker for ovarian cancer detection 2016 ·International Journal of Gynecological Cancer ·Adriaan Vanderstichele, Pieter Busschaert, Dominiek Smeets, Els Van Nieuwenhuysen, Karin Leunen, Patrick Neven, Frédéric Amant, Sven� Mahner, Elena Ioana Braicu, Robert Zeillinger, An Coosemans, D. Timmerman, Diether Lambrechts, Ignace Vergote	2
19	Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy ± Cetuximab 2013 ·Clinical Cancer Research ·Christopher G. Smith, David J. Fisher, Bart Claes, Tim Maughan, Shelley Idziaszczyk, Gilian Peuteman, Rebecca Harris, Michelle D. James, Angela Meade, Bharat Jasani, Richard Adams, Sarah Kenny, Richard Kaplan, Diether Lambrechts, Jeremy P. Cheadle	86
20	PIK3CA Mutations Are Not a Major Determinant of Resistance to the Epidermal Growth Factor Receptor Inhibitor Cetuximab in Metastatic Colorectal Cancer 2009 ·Clinical Cancer Research ·Hans Prenen, Jef De Schutter, Bart Jacobs, Wendy De Roock, Bart Biesmans, Bart Claes, Diether Lambrechts, Eric Van Cutsem, Sabine Tejpar	241

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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