Dennis Bigg

1.6k citations

47 papers · 1.3k indexed · h-index 20

Impact in

Toxicology top 0.5%
- Bioactive Compounds and Antitumor Agents
Organic Chemistry top 5%
- Synthesis and biological activity
- Synthetic Organic Chemistry Methods

Papers in

Toxicology 4
- Bioactive Compounds and Antitumor Agents 4
Organic Chemistry 24
- Chemical Synthesis and Reactions 4
- Chemical synthesis and alkaloids 4

Co-authors: Olivier Lavergne Guy Bertrand Laurence Lesueur‐Ginot Danièle Demarquay Marion Huchet Hélène Coulomb Philip G. Kasprzyk Alain Rolland
Journals: Bioorganic & Medicinal Chemistry Letters (12 papers)Synthesis (6 papers)The Journal of Organic Chemistry (4 papers)Journal of Medicinal Chemistry (3 papers)Annals of the New York Academy of Sciences (3 papers)
Partner nations: France United Kingdom Spain

In The Last Decade

Dennis Bigg

47 papers receiving 1.2k citations

Peers

Countries citing papers authored by Dennis Bigg

Since Specialization

Citations

This map shows the geographic impact of Dennis Bigg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dennis Bigg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dennis Bigg more than expected).

Fields of papers citing papers by Dennis Bigg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dennis Bigg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dennis Bigg. The network helps show where Dennis Bigg may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Dennis Bigg, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dennis Bigg Line = papers co-authored together Dennis Bigg links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Novel azoles as potent and selective cannabinoid CB2 receptor agonists Bioorganic & Medicinal Chemistry Letters ·S. Cavirani, Saning’o John Sindila, Isabelle Viossat, Leah Emary, Eric Ferrandis, Dennis Bigg, Michel Auguet, Stéphane Auvin, Caroline Bernardi	2014	4
2	IRC‐083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells International Journal of Cancer ·Marie-Christine Brézak, Annie Valette, Muriel Quaranta, Marie-Odile Contour-Galcéra, Denis Jullien, Olivier Lavergne, Céline Frongia, Dennis Bigg, Philip G. Kasprzyk, Grégoire Prévost, Bernard Ducommun	2008	42
3	Synthesis and bioevaluation of 22-hydroxyacuminatine analogs Bioorganic & Medicinal Chemistry Letters ·Dieli Simionatto, Su Jie Fan, Grégoire Prévost, Jean‐François Constant, Quvonchbek Sag`Dullayev, Dennis Bigg, Andrew E. Greene, Alice Kanazawa	2008	19
4	A novel synthetic CDC25 phosphatase inhibitor inhibits human cancer growth in vitro and in vivo Cancer Research ·Grégoire Prévost, Muriel Quaranta, Wang Zheng-zhao, Céline Frongia, 尚哉谷川, Quvonchbek Sag`Dullayev, Talia Kohen, Olivier Lavergne, Dennis Bigg, Annie Valette, Philip G. Kasprzyk, Bernard Ducommun	2007	1
5	What's new on CDC25 phosphatase inhibitors Pharmacology & Therapeutics ·Marie-Odile Contour-Galcéra, 尚哉谷川, P. Klinckhachom, Dennis Bigg, Bernard Ducommun	2007	63
6	Butyl 2-(4-[1.1′-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate, a potent sodium channel blocker for the treatment of neuropathic pain Bioorganic & Medicinal Chemistry Letters ·Leif Löher, Peter Toth, Rebecca Sarvendram, Jacques Pommier, Alfonso Muñoz Velasquez, ゆい竹中, Sherri Spelic, Marion Huchet, Michel Auguet, Pierre‐Etienne Chabrier, Dennis Bigg	2006	11
7	Novel dual inhibitors of calpain and lipid peroxidation with enhanced cellular activity Bioorganic & Medicinal Chemistry Letters ·Stéphane Auvin, Bernadette Pignol, Felice Achilli, D Sripurna, Denis Carré, José Camara, Dennis Bigg, Caroline Bernardi	2005	6
8	2-Alkyl-4-arylimidazoles: structurally novel sodium channel modulators Bioorganic & Medicinal Chemistry Letters ·Leif Löher, Peter Toth, Jacques Pommier, Sherri Spelic, Marion Huchet, Pierre‐Etienne Chabrier, Dennis Bigg	2004	9
9	Novel dual inhibitors of calpain and lipid peroxidation Bioorganic & Medicinal Chemistry Letters ·Stéphane Auvin, Bernadette Pignol, Felice Achilli, Jeffrey Min Hsin Chen, Horton Lawrence Fross, Dennis Bigg, Caroline Bernardi	2004	12
10	Phenolic thiazoles as novel orally-active neuroprotective agents Bioorganic & Medicinal Chemistry Letters ·S. Cavirani, L Dawydzik, Saning’o John Sindila, S Rippstein, B. Spinnewyn, 郭筱君, Alain Rolland, Jean‐Grégoire Marin, Dennis Bigg, Caroline Bernardi	2003	59
11	Novel inhibitors of neuronal nitric oxide synthase with potent antioxidant properties Bioorganic & Medicinal Chemistry Letters ·Stéphane Auvin, Michel Auguet, Felice Achilli, S. Cavirani, Isabelle Viossat, Peter Toth, Dennis Bigg, H. Matthies	2003	14
12	New Method of Synthesis of Vinca Alkaloid Derivatives Bioorganic & Medicinal Chemistry Letters ·Jacques Fahy, Peter W. E. Jacobsen, Dennis Bigg	2002	15
13	The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison Anti-Cancer Drugs ·Danièle Demarquay, Marion Huchet, Hélène Coulomb, Laurence Lesueur‐Ginot, Olivier Lavergne, Philip G. Kasprzyk, Christian Bailly, José Camara, Dennis Bigg	2001	24
14	Unusual potency of BN 80915, a novel fluorinated E-ring modified camptothecin, toward human colon carcinoma cells. PubMed ·Annette K. Larsen, Ioana Lazarescu, Zhengyun Pan, Sergey Plisov, Irina Naguibneva, Olivier Lavergne, Laurence Lesueur‐Ginot, Dennis Bigg	2001	31
15	The Dual Topoisomerase Inhibitor, BN 80927, Is Highly Potent against Cell Proliferation and Tumor Growth Annals of the New York Academy of Sciences ·Marion Huchet, Danièle Demarquay, Hélène Coulomb, Philip G. Kasprzyk, Mark A. Carlson, Yuto Nakagawa, Wang De-zhi, Dennis Bigg	2000	13
16	Homocamptothecins: E‐Ring Modified CPT Analogues Annals of the New York Academy of Sciences ·Olivier Lavergne, Danièle Demarquay, Philip G. Kasprzyk, Dennis Bigg	2000	20
17	BN 80927: A novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II Bioorganic & Medicinal Chemistry Letters ·Olivier Lavergne, S. Cavirani, Alain Rolland, Varvara Bazilova, Laurence Lesueur‐Ginot, Danièle Demarquay, Marion Huchet, Hélène Coulomb, Dennis Bigg	1999	40
18	Binding of antipsychotic drugs at α1A- and α1B-adrenoceptors: risperidone is selective for the α1B-adrenoceptors European Journal of Pharmacology ·Andrew J. Sleight, Wouter Koek, Dennis Bigg	1993	46
19	Characterization of Polymorphs and Solvates of 3-Amino-1-(m-trifluoromethylphenyl)-6-methyl-1H-pyridazin-4-one Journal of Pharmaceutical Sciences ·Alain Chauvet, Maria Antônia de Oliveira Porto, Jean‐Paul Ribet, Dennis Bigg, محمدرضا رهنما, Dawn O. Pratt, Jean‐François Patoiseau, J. Jaud	1992	12
20	Synthesis and reactivity of stable silyl-substituted nitrilimines The Journal of Organic Chemistry ·Г А Аверьянова, Antoine Baceiredo, Dennis Bigg, Guy Bertrand	1991	18

About Dennis Bigg

Dennis Bigg is a scholar working on Toxicology, Organic Chemistry, Oncology, Molecular Biology and Pharmacology, having authored 47 papers that have together received 1.3k indexed citations. Recurring topics across this work include Cancer therapeutics and mechanisms (13 papers), Neutropenia and Cancer Infections (10 papers), Lung Cancer Research Studies (7 papers), Bioactive Compounds and Antitumor Agents (4 papers), Chemical Synthesis and Analysis (4 papers), Phenothiazines and Benzothiazines Synthesis and Activities (4 papers), Chemical Synthesis and Reactions (4 papers) and Chemical synthesis and alkaloids (4 papers). The work is most often cited by research in Toxicology (244 citations), Organic Chemistry (507 citations), Oncology (354 citations), Molecular Biology (863 citations) and Biochemistry (52 citations). Dennis Bigg has collaborated with scholars based in France, United Kingdom and Spain. Frequent co-authors include Olivier Lavergne, Guy Bertrand, Laurence Lesueur‐Ginot, Danièle Demarquay, Marion Huchet, Hélène Coulomb, Philip G. Kasprzyk, Alain Rolland, Marie-Odile Contour-Galcéra and José Camara. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Synthesis, The Journal of Organic Chemistry, Journal of Medicinal Chemistry and Annals of the New York Academy of Sciences.

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