Debra L. Dugger

6.8k total citations · 3 hit papers
24 papers, 4.3k citations indexed

About

Debra L. Dugger is a scholar working on Molecular Biology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Debra L. Dugger has authored 24 papers receiving a total of 4.3k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 10 papers in Oncology and 7 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Debra L. Dugger's work include Cell death mechanisms and regulation (9 papers), Monoclonal and Polyclonal Antibodies Research (7 papers) and Ubiquitin and proteasome pathways (5 papers). Debra L. Dugger is often cited by papers focused on Cell death mechanisms and regulation (9 papers), Monoclonal and Polyclonal Antibodies Research (7 papers) and Ubiquitin and proteasome pathways (5 papers). Debra L. Dugger collaborates with scholars based in United States, France and Australia. Debra L. Dugger's co-authors include Kim Newton, Vishva M. Dixit, Joshua D. Webster, Merone Roose‐Girma, Katherine E. Wickliffe, László G. Kömüves, Ralph Schwall, Allie Maltzman, Elaine Mai and Mark X. Sliwkowski and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Debra L. Dugger

23 papers receiving 4.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

2008 1.3k citations Gail D. Lewis Phillips, Guangmin Li et al. Cancer Research profile →
Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

2014 531 citations Kim Newton, Debra L. Dugger et al. Science profile →
Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis

2019 407 citations Kim Newton, Katherine E. Wickliffe et al. Nature profile →

Peers

Countries citing papers authored by Debra L. Dugger

Since Specialization

Citations

This map shows the geographic impact of Debra L. Dugger's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Debra L. Dugger with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Debra L. Dugger more than expected).

Fields of papers citing papers by Debra L. Dugger

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Debra L. Dugger. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Debra L. Dugger. The network helps show where Debra L. Dugger may publish in the future.

Co-authorship network of co-authors of Debra L. Dugger

This figure shows the co-authorship network connecting the top 25 collaborators of Debra L. Dugger. A scholar is included among the top collaborators of Debra L. Dugger based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Debra L. Dugger. Debra L. Dugger is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Impairment of DET1 causes neurological defects and lethality in mice and humans 2025 ·Proceedings of the National Academy of Sciences ·Özge Karayel, Allison Soung, (unknown), Alexander F. Schubert, Susan Klaeger, Marc Kschonsak, (unknown), Ajaz A. Bhat, Ammira Al‐Shabeeb Akil, Debra L. Dugger, Joshua D. Webster, Dorothy French, (unknown), (unknown), Khalid A. Fakhro, Christopher M. Rose, Seth F. Harris, Ada Ndoja, Kim Newton, Vishva M. Dixit	2
2	cFLIP suppresses caspase-1- and MLKL-independent perinatal lethality driven by auto-processing impaired caspase-8 D387A 2025 ·Cell Death and Differentiation ·Kim Newton, Katherine E. Wickliffe, Allie Maltzman, Debra L. Dugger, Juan G. Reyes, (unknown), Søren Warming, Neha Rohatgi, Rohit Reja, Joshua D. Webster, Vishva M. Dixit	0
3	Caspase cleavage of RIPK3 after Asp333 is dispensable for mouse embryogenesis 2024 ·Cell Death and Differentiation ·Kim Newton, Katherine E. Wickliffe, Allie Maltzman, Debra L. Dugger, Joshua D. Webster, Hongyan Guo, Vishva M. Dixit	8
4	XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death 2023 ·Cell Death and Disease ·Axel Witt, Tatiana Goncharov, (unknown), Matthias Kist, Monika Dohse, (unknown), Debra L. Dugger, Kim Newton, Joshua D. Webster, Domagoj Vucic	5
5	Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death 2020 ·Cell Death and Differentiation ·Matthias Kist, László G. Kömüves, Tatiana Goncharov, Debra L. Dugger, Charles Q. Yu, Merone Roose‐Girma, Kim Newton, Joshua D. Webster, Domagoj Vucic	54
6	Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia 2020 ·Cell ·Ada Ndoja, Rohit Reja, Seung-Hye Lee, Joshua D. Webster, Hai Ngu, Christopher M. Rose, Donald S. Kirkpatrick, Zora Modrušan, (unknown), Debra L. Dugger, Vineela Gandham, Luke Xie, Kim Newton, Vishva M. Dixit	107
7	Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1 2019 ·Science ·Meng He, Mira S. Chaurushiya, Joshua D. Webster, Sarah Kummerfeld, Rohit Reja, Subhra Chaudhuri, Ying‐Jiun Chen, Zora Modrušan, Benjamin Haley, Debra L. Dugger, Jeffrey Eastham‐Anderson, (unknown), Anwesha Dey, Roger Caothien, Merone Roose‐Girma, Kim Newton, Vishva M. Dixit	71
8	Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis breakdown → 2019 ·Nature ·Kim Newton, Katherine E. Wickliffe, Debra L. Dugger, Allie Maltzman, Merone Roose‐Girma, Monika Dohse, László G. Kömüves, Joshua D. Webster, Vishva M. Dixit	407
9	Activity of caspase-8 determines plasticity between cell death pathways 2019 ·Nature ·Kim Newton, Katherine E. Wickliffe, Allie Maltzman, Debra L. Dugger, Rohit Reja, Yue Zhang, Merone Roose‐Girma, Zora Modrušan, Meredith Sagolla, Joshua D. Webster, Vishva M. Dixit	289
10	The RIPK4–IRF6 signalling axis safeguards epidermal differentiation and barrier function 2019 ·Nature ·(unknown), Victoria C. Pham, Joshua D. Webster, Rohit Reja, Christine Huang, Yue Zhang, Merone Roose‐Girma, Søren Warming, Qingling Li, (unknown), (unknown), Wendy Sandoval, László G. Kömüves, Kebing Yu, Debra L. Dugger, Allie Maltzman, Kim Newton, Vishva M. Dixit	54
11	Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation 2019 ·Cell Reports ·Jieqiong Zhang, Joshua D. Webster, Debra L. Dugger, Tatiana Goncharov, Merone Roose‐Girma, Jeffrey Hung, Youngsu Kwon, Domagoj Vucic, Kim Newton, Vishva M. Dixit	49
12	RIPK1 inhibits ZBP1-driven necroptosis during development 2016 ·Nature ·Kim Newton, Katherine E. Wickliffe, Allie Maltzman, Debra L. Dugger, Andreas Strasser, Victoria C. Pham, Jennie R. Lill, Merone Roose‐Girma, Søren Warming, Margaret Solon, Hai Ngu, Joshua D. Webster, Vishva M. Dixit	307
13	β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1 2015 ·Cell ·Rowena Suriben, Kelly A. Kaihara, Magdalena Paolino, Mike Reichelt, Sarah Kummerfeld, Zora Modrušan, Debra L. Dugger, Kim Newton, Meredith Sagolla, Joshua D. Webster, Jinfeng Liu, Matthias Hebrok, Vishva M. Dixit	46
14	Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis breakdown → 2014 ·Science ·Kim Newton, Debra L. Dugger, Katherine E. Wickliffe, Neeraj Kapoor, M. Cristina de Almagro, Domagoj Vucic, László G. Kömüves, Ronald E. Ferrando, Dorothy French, Joshua D. Webster, Merone Roose‐Girma, Søren Warming, Vishva M. Dixit	531
15	Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer 2010 ·Clinical Cancer Research ·Jagath R. Junutula, Kelly M. Flagella, Richard Graham, Kathryn L. Parsons, (unknown), Helga Raab, Sunil Bhakta, Trung Van Nguyen, Debra L. Dugger, Guangmin Li, Elaine Mai, Gail D. Lewis Phillips, Hajime Hiraragi, Reina N. Fuji, Jay Tibbitts, Richard Vandlen, Susan D. Spencer, Richard H. Scheller, Paul Polakis, Mark X. Sliwkowski	214
16	Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice 2010 ·Journal of Pharmacokinetics and Pharmacodynamics ·Nelson L. ‘Shasha’ Jumbe, Xin Yan, Douglas D. Leipold, Lisa Crocker, Debra L. Dugger, Elaine Mai, Mark X. Sliwkowski, Paul J. Fielder, Jay Tibbitts	90
17	Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies 2008 ·Cell ·Kim Newton, M Matsumoto, Ingrid E. Wertz, Donald S. Kirkpatrick, Jennie R. Lill, Jenille Tan, Debra L. Dugger, Nathaniel C. Gordon, Sachdev S. Sidhu, Frédéric A. Fellouse, László G. Kömüves, Dorothy French, Ronald E. Ferrando, Cynthia Lam, Deanne M. Compaan, Christine Yu, Ivan Bosanac, S.G. Hymowitz, Robert F. Kelley, Vishva M. Dixit	473
18	Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate breakdown → 2008 ·Cancer Research ·Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger, Lisa Crocker, Kathryn L. Parsons, Elaine Mai, Walter A. Blättler, John M. Lambert, Ravi Chari, Robert J. Lutz, Wai Lee Wong, (unknown), Hartmut Koeppen, Ralph Schwall, Sara Kenkare-Mitra, Susan D. Spencer, Mark X. Sliwkowski	1259
19	Trastuzumab-MC-vc-PAB-MMAF: The effects of the Drug:Antibody Ratio (DAR) on efficacy, toxicity and pharmacokinetics. 2007 ·Cancer Research ·Douglas D. Leipold, Nelson L. ‘Shasha’ Jumbe, Debra L. Dugger, Lisa Crocker, (unknown), Mark X. Sliwkowski, Damon L. Meyer, Peter D. Senter, Jay Tibbitts	3
20	Long-Term Erythropoietin Expression in Rodents and Non-Human Primates Following Intramuscular Injection of a Replication-Defective Adenoviral Vector 1997 ·Human Gene Therapy ·E. C. Svensson, Hugh B. Black, Debra L. Dugger, Sandeep K. Tripathy, Eugene Goldwasser, (unknown), Lien Chu, Jeffrey M. Leiden	82

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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