David S. Waugh

9.6k citations

140 papers · 7.7k indexed · 1 hit paper · h-index 48

Impact in

Endocrinology top 0.5%
Molecular Biology top 1%
- RNA and protein synthesis mechanisms
- Protein purification and stability
- Viral Infectious Diseases and Gene Expression in Insects

Papers in

Genetics 57
- Bacterial Genetics and Biotechnology 34
- Yersinia bacterium, plague, ectoparasites research 25
Endocrinology 9

Co-authors: Rachel B. Kapust Joseph E. Tropea Sreedevi Nallamsetty Scott Cherry Karen M. Routzahn A.G. Evdokimov Brian Austin Xinhua Ji
Journals: Protein Expression and Purification (13 papers)Protein Science (12 papers)Journal of Molecular Biology (8 papers)Journal of Biological Chemistry (7 papers)Structure (6 papers)
Partner nations: United States Hungary Switzerland

In The Last Decade

David S. Waugh

139 papers receiving 7.5k citations

Hit Papers

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Escherichia coli maltose‐binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fused 1999 · 770 citations

Peers

Countries citing papers authored by David S. Waugh

Since Specialization

Citations

This map shows the geographic impact of David S. Waugh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David S. Waugh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David S. Waugh more than expected).

Fields of papers citing papers by David S. Waugh

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David S. Waugh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David S. Waugh. The network helps show where David S. Waugh may publish in the future.

Co-authors

The 25 scholars most cited alongside David S. Waugh, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David S. Waugh Line = papers co-authored together David S. Waugh links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	P1′ specificity of the S219V/R203G mutant tobacco etch virus protease Proteins Structure Function and Bioinformatics ·Sophia Davidov, R.V. McMillen, Scott Cherry, Joseph E. Tropea, G.T. Lountos, David S. Waugh, Alexander Wlodawer, József Tőzsér, János András Mótyán	2024	0
2	Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites Chemical Science ·Xue Zhi Zhao, Evgeny Kiselev, G.T. Lountos, Wenjie Wang, Joseph E. Tropea, D. Needle, Thomas A. Hilimire, John S. Schneekloth, David S. Waugh, Yves Pommier, Terrence R. Burke	2021	27
3	Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9 Angewandte Chemie ·William M. Hewitt, G.T. Lountos, Yecheng Ding, Samuel D. Dahlhauser, Lindsey B. Saunders, D. Needle, Joseph E. Tropea, Chendi Zhan, Guanghong Wei, Buyong Ma, Ruth Nussinov, David S. Waugh, John S. Schneekloth	2016	1
4	Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9 Angewandte Chemie International Edition ·William M. Hewitt, G.T. Lountos, Yecheng Ding, Samuel D. Dahlhauser, Lindsey B. Saunders, D. Needle, Joseph E. Tropea, Chendi Zhan, Guanghong Wei, Buyong Ma, Ruth Nussinov, David S. Waugh, John S. Schneekloth	2016	16
5	Positional effects of fusion partners on the yield and solubility of MBP fusion proteins Protein Expression and Purification ·Sreejith Raran‐Kurussi, Alice Evatt, David S. Waugh	2015	37
6	Structures of theMiddle East respiratory syndrome coronavirus3C-like protease reveal insights into substrate specificity Acta Crystallographica Section D Biological Crystallography ·D. Needle, G.T. Lountos, David S. Waugh	2015	86
7	Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases Analytical Biochemistry ·Sreejith Raran‐Kurussi, József Tőzsér, Scott Cherry, Joseph E. Tropea, David S. Waugh	2013	20
8	Structure of human dual-specificity phosphatase 27 at 2.38 Å resolution Acta Crystallographica Section D Biological Crystallography ·G.T. Lountos, Joseph E. Tropea, David S. Waugh	2011	17
9	Overproduction, Purification and Structure Determination of Human Dual Specificity Phosphatase 14 Biophysical Journal ·G.T. Lountos, Joseph E. Tropea, Scott Cherry, David S. Waugh	2010	8
10	Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase Structure ·Chao Tu, Joseph E. Tropea, Brian Austin, Donald L. Court, David S. Waugh, Xinhua Ji	2009	26
11	Molecular cloning, overproduction, purification and biochemical characterization of the p39 nsp2 protease domains encoded by three alphaviruses Protein Expression and Purification ·Di Zhang, József Tőzsér, David S. Waugh	2008	22
12	Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor Protein Science ·G.T. Lountos, Joseph E. Tropea, Di Zhang, Andrew G. Jobson, Yves Pommier, Robert H. Shoemaker, David S. Waugh	2008	25
13	Hexahistidine-Tagged Maltose-Binding Protein as a Fusion Partner for the Production of Soluble Recombinant Proteins in Escherichia coli Methods in molecular biology ·Brian Austin, Sreedevi Nallamsetty, David S. Waugh	2008	28
14	A generic protocol for the expression and purification of recombinant proteins in Escherichia coli using a combinatorial His6-maltose binding protein fusion tag Nature Protocols ·Sreedevi Nallamsetty, David S. Waugh	2007	91
15	Structural Insight into the Mechanism of Double-Stranded RNA Processing by Ribonuclease III Cell ·Jianhua Gan, Joseph E. Tropea, Brian Austin, Donald L. Court, David S. Waugh, Xinhua Ji	2006	185
16	Overproduction, purification, and biochemical characterization of the dual specificity H1 protein phosphatase encoded by variola major virus Protein Expression and Purification ·Joseph E. Tropea, Jason Phan, David S. Waugh	2006	11
17	Processive Degradation of Nascent Polypeptides, Triggered by Tandem AGA Codons, Limits the Accumulation of Recombinant Tobacco Etch Virus Protease in Escherichia coli BL21(DE3) Protein Expression and Purification ·Rachel B. Kapust, Karen M. Routzahn, David S. Waugh	2002	29
18	Crystallization and preliminary X-ray diffraction studies of NusG, a protein shared by the transcription and translation machines Acta Crystallographica Section D Biological Crystallography ·Arne Ansper, Wei Guo, Karen M. Routzahn, Yijun Gu, David E. Anderson, L. Reshetnikova, Erika Lencsés-Varga, David S. Waugh, Xinhua Ji	2002	6
19	Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of ras (KSR) Journal of Molecular Biology ·Ming Zhou, David A. Horita, David S. Waugh, R. Andrew Byrd, Deborah K. Morrison	2002	77
20	Crystallographic and Modeling Studies of RNase III Suggest a Mechanism for Double-Stranded RNA Cleavage Structure ·Jarosław Błaszczyk, Joseph E. Tropea, Mikhail Bubunenko, Karen M. Routzahn, David S. Waugh, Donald L. Court, Xinhua Ji	2001	186

About David S. Waugh

David S. Waugh is a scholar working on Genetics, Endocrinology, Molecular Biology, Pharmacology and Ecology, having authored 140 papers that have together received 7.7k indexed citations. Recurring topics across this work include Bacterial Genetics and Biotechnology (34 papers), Bacteriophages and microbial interactions (28 papers), RNA and protein synthesis mechanisms (25 papers), Yersinia bacterium, plague, ectoparasites research (25 papers), Protein purification and stability (20 papers), Enzyme Structure and Function (19 papers), Protein Tyrosine Phosphatases (18 papers) and Monoclonal and Polyclonal Antibodies Research (17 papers). The work is most often cited by research in Endocrinology (577 citations), Molecular Biology (5.8k citations), Genetics (1.8k citations), Biotechnology (397 citations) and Radiology, Nuclear Medicine and Imaging (1.0k citations). David S. Waugh has collaborated with scholars based in United States, Hungary and Switzerland. Frequent co-authors include Rachel B. Kapust, Joseph E. Tropea, Sreedevi Nallamsetty, Scott Cherry, Karen M. Routzahn, A.G. Evdokimov, Brian Austin, Xinhua Ji, Donald L. Court and József Tőzsér. Their work appears in journals such as Protein Expression and Purification, Protein Science, Journal of Molecular Biology, Journal of Biological Chemistry and Structure.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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