D. Needle

541 total citations
17 papers, 419 citations indexed

About

D. Needle is a scholar working on Molecular Biology, Infectious Diseases and Organic Chemistry. According to data from OpenAlex, D. Needle has authored 17 papers receiving a total of 419 indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 4 papers in Infectious Diseases and 3 papers in Organic Chemistry. Recurrent topics in D. Needle's work include Cancer therapeutics and mechanisms (4 papers), Viral gastroenteritis research and epidemiology (3 papers) and Protein Degradation and Inhibitors (3 papers). D. Needle is often cited by papers focused on Cancer therapeutics and mechanisms (4 papers), Viral gastroenteritis research and epidemiology (3 papers) and Protein Degradation and Inhibitors (3 papers). D. Needle collaborates with scholars based in United States, Israel and China. D. Needle's co-authors include David S. Waugh, G.T. Lountos, Joseph E. Tropea, Chitrita DebRoy, Pina M. Fratamico, Connie Briggs, Chin‐Yi Chen, Jacek Capala, Ilya Lyakhov and Brandon Smith and has published in prestigious journals such as Nucleic Acids Research, Angewandte Chemie International Edition and PLoS ONE.

In The Last Decade

D. Needle

17 papers receiving 410 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
D. Needle United States 11 211 127 75 61 57 17 419
Christine K. Maurer Germany 13 634 3.0× 85 0.7× 46 0.6× 72 1.2× 16 0.3× 21 827
Riley L. Svec United States 6 351 1.7× 85 0.7× 27 0.4× 239 3.9× 21 0.4× 7 812
Anke Steinbach Germany 14 680 3.2× 92 0.7× 51 0.7× 97 1.6× 15 0.3× 18 884
Yuxin Ye China 11 283 1.3× 146 1.1× 22 0.3× 74 1.2× 8 0.1× 28 486
Jorge Ramos Portugal 13 376 1.8× 517 4.1× 32 0.4× 132 2.2× 10 0.2× 26 901
Cenbin Lu Germany 6 446 2.1× 56 0.4× 31 0.4× 67 1.1× 15 0.3× 7 600
Daina Zeng United States 9 220 1.0× 97 0.8× 32 0.4× 76 1.2× 5 0.1× 12 447
Jason E. Cummings United States 14 307 1.5× 102 0.8× 15 0.2× 134 2.2× 11 0.2× 34 579
Catrien Bouwman Canada 9 259 1.2× 37 0.3× 112 1.5× 77 1.3× 6 0.1× 9 556

Countries citing papers authored by D. Needle

Since Specialization
Citations

This map shows the geographic impact of D. Needle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by D. Needle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites D. Needle more than expected).

Fields of papers citing papers by D. Needle

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by D. Needle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by D. Needle. The network helps show where D. Needle may publish in the future.

Co-authorship network of co-authors of D. Needle

This figure shows the co-authorship network connecting the top 25 collaborators of D. Needle. A scholar is included among the top collaborators of D. Needle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with D. Needle. D. Needle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

17 of 17 papers shown
1.
Zhao, Xue Zhi, Wenjie Wang, G.T. Lountos, et al.. (2023). Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification. RSC Chemical Biology. 4(5). 334–343. 7 indexed citations
2.
Lountos, G.T., D. Needle, Alexander Wlodawer, et al.. (2023). Self-inhibited State of Venezuelan Equine Encephalitis Virus (VEEV) nsP2 Cysteine Protease: A Crystallographic and Molecular Dynamics Analysis. Journal of Molecular Biology. 435(6). 168012–168012. 2 indexed citations
3.
Zhao, Xue Zhi, Wenjie Wang, G.T. Lountos, et al.. (2022). Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1. Frontiers in Chemistry. 10. 910953–910953. 5 indexed citations
4.
Zhao, Xue Zhi, Evgeny Kiselev, G.T. Lountos, et al.. (2021). Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites. Chemical Science. 12(11). 3876–3884. 27 indexed citations
5.
Giddings, LesleyAnn, G.T. Lountos, D. Needle, et al.. (2021). Characterization of a broadly specific cadaverine N-hydroxylase involved in desferrioxamine B biosynthesis in Streptomyces sviceus. PLoS ONE. 16(3). e0248385–e0248385. 9 indexed citations
6.
7.
Jin, Lan, Joseph E. Tropea, D. Needle, et al.. (2019). The molecular mechanism of dsRNA processing by a bacterial Dicer. Nucleic Acids Research. 47(9). 4707–4720. 14 indexed citations
8.
Hewitt, William M., Joseph E. Tropea, D. Needle, et al.. (2017). A Small-Molecule Microarray Approach for the Identification of E2 Enzyme Inhibitors in Ubiquitin-Like Conjugation Pathways. SLAS DISCOVERY. 22(6). 760–766. 22 indexed citations
9.
Hewitt, William M., G.T. Lountos, Samuel D. Dahlhauser, et al.. (2016). Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angewandte Chemie. 128(19). 5797–5801. 1 indexed citations
10.
Hewitt, William M., G.T. Lountos, Samuel D. Dahlhauser, et al.. (2016). Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angewandte Chemie International Edition. 55(19). 5703–5707. 16 indexed citations
11.
Needle, D., G.T. Lountos, & David S. Waugh. (2015). Structures of theMiddle East respiratory syndrome coronavirus3C-like protease reveal insights into substrate specificity. Acta Crystallographica Section D Biological Crystallography. 71(5). 1102–1111. 86 indexed citations
12.
Needle, D. & David S. Waugh. (2014). Rescuing Aggregation-Prone Proteins in Escherichia coli with a Dual His6-MBP Tag. Methods in molecular biology. 1177. 81–94. 9 indexed citations
13.
Shaw, G., Genbin Shi, Yan Wu, et al.. (2014). Structural enzymology and inhibition of the bi‐functional folate pathway enzyme HPPKDHPS from the biowarfare agent Francisella tularensis. FEBS Journal. 281(18). 4123–4137. 10 indexed citations
14.
Zieliński, Rafał, Moinuddin Hassan, Ilya Lyakhov, et al.. (2012). Affibody-DyLight Conjugates for In Vivo Assessment of HER2 Expression by Near-Infrared Optical Imaging. PLoS ONE. 7(7). e41016–e41016. 18 indexed citations
15.
Smith, Brandon, Ilya Lyakhov, Kristin H. Loomis, et al.. (2011). Hyperthermia-triggered intracellular delivery of anticancer agent to HER2+ cells by HER2-specific affibody (ZHER2-GS-Cys)-conjugated thermosensitive liposomes (HER2+ affisomes). Journal of Controlled Release. 153(2). 187–194. 70 indexed citations
16.
Fratamico, Pina M., Connie Briggs, D. Needle, Chin‐Yi Chen, & Chitrita DebRoy. (2003). Sequence of the Escherichia coli O121 O-Antigen Gene Cluster and Detection of Enterohemorrhagic E. coli O121 by PCR Amplification of the wzx and wzy Genes. Journal of Clinical Microbiology. 41(7). 3379–3383. 67 indexed citations
17.
White, David G., Shaohua Zhao, Patrick F. McDermott, et al.. (2002). Characterization of Antimicrobial Resistance Among Escherichia coli O111 Isolates of Animal and Human Origin. Microbial Drug Resistance. 8(2). 139–146. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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