David Pearce

9.0k total citations · 1 hit paper
112 papers, 7.3k citations indexed

About

David Pearce is a scholar working on Molecular Biology, Endocrinology, Diabetes and Metabolism and Genetics. According to data from OpenAlex, David Pearce has authored 112 papers receiving a total of 7.3k indexed citations (citations by other indexed papers that have themselves been cited), including 75 papers in Molecular Biology, 45 papers in Endocrinology, Diabetes and Metabolism and 24 papers in Genetics. Recurrent topics in David Pearce's work include Ion Transport and Channel Regulation (49 papers), Hormonal Regulation and Hypertension (40 papers) and Electrolyte and hormonal disorders (20 papers). David Pearce is often cited by papers focused on Ion Transport and Channel Regulation (49 papers), Hormonal Regulation and Hypertension (40 papers) and Electrolyte and hormonal disorders (20 papers). David Pearce collaborates with scholars based in United States, Germany and Switzerland. David Pearce's co-authors include Aditi Bhargava, Keith R. Yamamoto, Rama Soundararajan, Jian Wang, Onno C. Meijer, Gary L. Firestone, François Verrey, Jian Wang, Jorge A. Iñiguez‐Lluhí and Luca Mastroberardino and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

David Pearce

111 papers receiving 7.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Epithelial sodium channel regulated by aldosterone-induced protein sgk

1999 626 citations Aditi Bhargava, Luca Mastroberardino et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David Pearce United States	49	4.6k	2.5k	1.3k	1.3k	890	112	7.3k
Anikó Náray‐Fejes‐Tóth United States	39	2.8k 0.6×	1.9k 0.8×	843 0.6×	476 0.4×	685 0.8×	90	4.5k
Marc Lombès France	51	3.1k 0.7×	4.3k 1.7×	638 0.5×	1.7k 1.3×	1.7k 1.9×	191	8.2k
Donald Defranco United States	55	5.3k 1.2×	1.3k 0.5×	761 0.6×	2.3k 1.8×	248 0.3×	165	9.1k
Zygmunt S. Krozowski Australia	46	2.5k 0.5×	4.9k 2.0×	735 0.6×	1.6k 1.3×	1.2k 1.4×	131	7.8k
Nadine Binart France	54	3.8k 0.8×	3.9k 1.6×	302 0.2×	2.8k 2.2×	749 0.8×	154	10.5k
James L. Roberts United States	56	3.3k 0.7×	1.9k 0.8×	558 0.4×	1.4k 1.1×	542 0.6×	188	10.8k
Albert F. Parlow United States	48	2.7k 0.6×	2.5k 1.0×	331 0.3×	1.8k 1.4×	514 0.6×	150	8.4k
Michael J. Garabedian United States	54	5.0k 1.1×	1.4k 0.6×	895 0.7×	2.9k 2.3×	602 0.7×	133	9.6k
A. Negro‐Vilar United States	56	2.6k 0.6×	2.5k 1.0×	460 0.4×	1.3k 1.0×	613 0.7×	233	9.4k
Markku Pelto‐Huikko Finland	49	4.6k 1.0×	1.5k 0.6×	535 0.4×	4.9k 3.8×	855 1.0×	142	10.9k

Countries citing papers authored by David Pearce

Since Specialization

Citations

This map shows the geographic impact of David Pearce's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Pearce with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Pearce more than expected).

Fields of papers citing papers by David Pearce

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Pearce. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Pearce. The network helps show where David Pearce may publish in the future.

Co-authorship network of co-authors of David Pearce

This figure shows the co-authorship network connecting the top 25 collaborators of David Pearce. A scholar is included among the top collaborators of David Pearce based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Pearce. David Pearce is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Saha, Bidisha, et al.. (2025). Coordinated Regulation of Renal Glucose Reabsorption and Gluconeogenesis by mTORC2 and Potassium. Journal of the American Society of Nephrology. 36(9). 1733–1748.

Yu, Zanlin, Feng Wang, Bidisha Saha, et al.. (2022). Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. Journal of Biological Chemistry. 298(9). 102288–102288. 23 indexed citations

Pearce, David, et al.. (2022). Regulation of distal tubule sodium transport: mechanisms and roles in homeostasis and pathophysiology. Pflügers Archiv - European Journal of Physiology. 474(8). 869–884. 28 indexed citations

Dowling, Mark R., Cara E. Brocklehurst, Michael Faller, et al.. (2018). Development of autotaxin inhibitors: A series of zinc binding triazoles. Bioorganic & Medicinal Chemistry Letters. 28(13). 2279–2284. 9 indexed citations

Soundararajan, Rama, Ming Lu, & David Pearce. (2012). Organization of the ENaC-regulatory machinery. Critical Reviews in Biochemistry and Molecular Biology. 47(4). 349–359. 40 indexed citations

Soundararajan, Rama, et al.. (2012). Scaffold Protein Connector Enhancer of Kinase Suppressor of Ras Isoform 3 (CNK3) Coordinates Assembly of a Multiprotein Epithelial Sodium Channel (ENaC)-regulatory Complex. Journal of Biological Chemistry. 287(39). 33014–33025. 25 indexed citations

Soundararajan, Rama, et al.. (2011). The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport. Molecular and Cellular Endocrinology. 350(2). 242–247. 53 indexed citations

Pao, Alan C., Aditi Bhargava, Francesca Di Sole, et al.. (2010). Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na ⁺ /H ⁺ exchanger 3 in the mammalian kidney. American Journal of Physiology-Renal Physiology. 299(6). F1496–F1506. 39 indexed citations

Pasham, Venkanna, Anand Rotte, Madhuri Bhandaru, et al.. (2010). Regulation of gastric acid secretion by the serum and glucocorticoid inducible kinase isoform SGK3. Journal of Gastroenterology. 46(3). 305–317. 6 indexed citations

10.

Kempe, Daniela S., Teresa F. Ackermann, Krishna M. Boini, et al.. (2010). Akt2/PKBβ‐sensitive regulation of renal phosphate transport. Acta Physiologica. 200(1). 75–85. 15 indexed citations

11.

Soundararajan, Rama, Jian Wang, Daniël P. Melters, & David Pearce. (2010). Glucocorticoid-induced Leucine Zipper 1 Stimulates the Epithelial Sodium Channel by Regulating Serum- and Glucocorticoid-induced Kinase 1 Stability and Subcellular Localization. Journal of Biological Chemistry. 285(51). 39905–39913. 42 indexed citations

12.

Soundararajan, Rama, et al.. (2005). A Novel Role for Glucocorticoid-induced Leucine Zipper Protein in Epithelial Sodium Channel-mediated Sodium Transport. Journal of Biological Chemistry. 280(48). 39970–39981. 151 indexed citations

13.

Ni, Xi-Ping, David Pearce, Andrew A. Butler, Roger D. Cone, & Michael H. Humphreys. (2003). Genetic disruption of γ-melanocyte–stimulating hormone signaling leads to salt-sensitive hypertension in the mouse. Journal of Clinical Investigation. 111(8). 1251–1258. 59 indexed citations

14.

Verrey, François, David Pearce, Rahel Pfeiffer, et al.. (2000). Pleiotropic action of aldosterone in epithelia mediated by transcription and post-transcription mechanisms. Kidney International. 57(4). 1277–1282. 68 indexed citations

15.

Wissink, Sacha, Onno C. Meijer, David Pearce, Bart van der Burg, & Paul T. van der Saag. (2000). Regulation of the Rat Serotonin-1A Receptor Gene by Corticosteroids. Journal of Biological Chemistry. 275(2). 1321–1326. 63 indexed citations

16.

Wang, Jian, et al.. (1997). Androgen and Glucocorticoid Receptor Heterodimer Formation. Journal of Biological Chemistry. 272(22). 14087–14092. 159 indexed citations

17.

Tattersall, F.D., Wayne Rycroft, B. Francis, et al.. (1996). Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets. Neuropharmacology. 35(8). 1121–1129. 189 indexed citations

18.

Hutson, Peter H., Linda J. Bristow, J.R. Cunningham, et al.. (1995). The effects of GR127935, a putative 5-HT1D receptor antagonist, on brain 5-HT metabolism, extracellular 5-HTT concentration and behaviour in the guinea pig. Neuropharmacology. 34(4). 383–392. 33 indexed citations

19.

Yamamoto, Keith R., et al.. (1992). 43 Combinatorial Regulation at a Mammalian Composite Response Element. Cold Spring Harbor Monograph Archive. 1169–1192. 7 indexed citations

20.

Krapf, Reto, David Pearce, Colleen D. Lynch, et al.. (1991). Expression of rat renal Na/H antiporter mRNA levels in response to respiratory and metabolic acidosis.. Journal of Clinical Investigation. 87(2). 747–751. 53 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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