David Middlemiss

1.4k citations

45 papers · 993 indexed · h-index 20

Impact in

Organic Chemistry top 5%
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Catalytic Alkyne Reactions
- Catalytic C–H Functionalization Methods
Inorganic Chemistry top 10%
- Asymmetric Hydrogenation and Catalysis

Papers in

Organic Chemistry 30
- Asymmetric Synthesis and Catalysis 10
- Synthetic Organic Chemistry Methods 7
- Chemical synthesis and alkaloids 6
- Catalytic Cross-Coupling Reactions 4
Pharmaceutical Science 3

Co-authors: William J. Kerr Stephen G. Davies Alan Naylor Steve P. Watson Steven J. Coote Joseph P. A. Harrity Duncan B. Judd Barry C. Ross
Journals: Tetrahedron Letters (8 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Medicinal Chemistry (5 papers)Tetrahedron (3 papers)Journal of Organometallic Chemistry (3 papers)
Partner nations: United Kingdom Australia New Zealand

In The Last Decade

David Middlemiss

45 papers receiving 919 citations

Peers

Countries citing papers authored by David Middlemiss

Since Specialization

Citations

This map shows the geographic impact of David Middlemiss's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Middlemiss with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Middlemiss more than expected).

Fields of papers citing papers by David Middlemiss

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Middlemiss. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Middlemiss. The network helps show where David Middlemiss may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David Middlemiss, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Middlemiss Line = papers co-authored together David Middlemiss links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Fragment-based and structure-guided discovery of perforin inhibitors European Journal of Medicinal Chemistry ·Jiney Jose, Ruby H. P. Law, Eleanor W. W. Leung, Dorothy C.C. Wai, Abdul Rohman, Indu R. Chandrashekaran, Tom T. Caradoc-Davies, Ilia Voskoboinik, 李晓琴, David Middlemiss, Rick Brandenstein, Tanya A. Bashtannyk-Puhalovich, О.А. Нелень, Tet Woo Lee, Stephen M. F. Jamieson, Joseph A. Trapani, James C. Whisstock, Julie A. Spicer, Raymond S. Norton	2023	2
2	Indole-3-acetic Acid Antagonists of the Prostaglandin D₂ Receptor CRTH2 Journal of Medicinal Chemistry ·Richard Armer, Mark Ashton, Miguel Domínguez Iturza, Charlotte Karlstrand, Frederick A. Brookfield, Lucien Gazi, Shân L. Gyles, 園部誠, Michael Hunter, David Middlemiss, Mark Whittaker, Luzheng Xue, Roy Pettipher	2005	39
3	Serotonergic targets in depression Current Opinion in Pharmacology ·David Middlemiss	2002	71
4	Tetrazole NK1 receptor antagonists: The identification of an exceptionally potent orally active antiemetic compound Bioorganic & Medicinal Chemistry Letters ·Duncan Armour, Kyeongwoon Chung, Miles Congreve, Brian Evans, Stephen B. Guntrip, Thomas Hubbard, Sabine Bell, David Middlemiss, J.E. Mordaunt, Neil Pegg, V. Vinader, P. Ward, 耕輝伊藤	1996	34
5	A convenient procedure for the solution phase preparation of 2-aminothiazole combinatorial libraries Bioorganic & Medicinal Chemistry Letters ·Nicholas Bailey, Anthony Dean, Duncan B. Judd, David Middlemiss, Richard Storer, Steve P. Watson	1996	84
6	Facile Synthesis of Functionalised β-Lactones; Novel Cyclisations of Chromium Carbene Complexes with Propargylic Alcohols Synlett ·Byambajav Munkhjargal, Nicola M. Heron, William J. Kerr, Carolyn Green, David Middlemiss, James S. Scott	1996	12
7	Discovery of an Orally Bioavailable NK1 Receptor Antagonist, (2S,3S)-(2-Methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine (GR203040), with Potent Antiemetic Activity Journal of Medicinal Chemistry ·P. Ward, Duncan Armour, N.M. Pavliuk, Brian Evans, Gerard M.P. Giblin, Nicola M. Heron, Per-Anders Clason, Kai Liang, David Middlemiss	1995	41
8	Highly Efficient Enantioselective Pauson-Khand Reactions Organometallics ·Lara Cristina Mesquita de Morais, William J. Kerr, Ammar G. Samir, David Middlemiss	1995	70
9	Enantioselective Pauson-Khand Reactions Mediated by a Chiral Amine N-Oxide Synlett ·William J. Kerr, Ammar G. Samir, David Middlemiss	1995	42
10	Cardiovascular effects of GR117289, a novel angiotensin AT₁ receptor antagonist British Journal of Pharmacology ·A. Hilditch, J. Jasinski, C. Gardner, D.J. Twissell, S. Belin, A. Travers, G.M. Drew, David Middlemiss, Barry C. Ross, Mark J. Robertson	1994	21
11	Bromobenzofuran-Based Non-peptide Antagonists of Angiotensin II: GR138950, a Potent Antihypertensive Agent with High Oral Bioavailability Journal of Medicinal Chemistry ·Duncan B. Judd, Michael D. Dowle, David Middlemiss, D. I. C. SCOPES, Barry C. Ross, T. Pasilio, Martin Pass, Hiramani Patgiri, Kimia Rajabzadeh Tabari	1994	33
12	Comparative pharmacology of recombinant rat AT_1A, AT_1Band human AT₁receptors expressed by transfected COS‐M6 cells British Journal of Pharmacology ·Anthony J. Balmforth, Susan E. Bryson, Gustavo Soroka, Philip Warburton, Stephen G. Ball, Kwok‐Tao Pun, David Middlemiss, G.M. Drew	1994	13
13	Promotion of the chromium carbene Dötz annulation reaction under sonochemical and dry state adsorption conditions Tetrahedron ·Joseph P. A. Harrity, William J. Kerr, David Middlemiss	1993	41
14	Pharmacological profile of GR117289 in vitro: a novel, potent and specific non‐peptide angiotensin AT₁ receptor antagonist British Journal of Pharmacology ·Mark J. Robertson, Jen Barnes, G.M. Drew, Kenneth L. Clark, Fiona H. Marshall, A.D. Michel, David Middlemiss, Barry C. Ross, D. I. C. SCOPES, Michael D. Dowle	1992	66
15	Bridged-ring nitrogen compounds. Part 10. Synthesis of bridged 3-benzazepine derivatives as conformationally restricted dopamine analogues Journal of the Chemical Society Perkin Transactions 1 ·Robert G. Gentles, David Middlemiss, George R. Proctor, Algebra its Relation to Analysis	1991	11
16	Chiral recognition in the reaction of the enolate derived from [(η⁵-C₅H₅)Fe(CO)(PPh₃)COCH₂OCH₂Ph] with 1-phenylethyl bromide Journal of the Chemical Society Chemical Communications ·Stephen G. Davies, David Middlemiss, Alan Naylor, Martin Wills	1990	15
17	Chiral recognition in the reaction of the enolate derived from [(η5-C5H5)Fe(CO)(PPh3)COCH2OCH2Ph] with cis- and trans-2,3-epoxybutane: The stereoselective synthesis of cis and trans-βγ-disubstituted-γ-lactones Tetrahedron Letters ·Stephen G. Davies, David Middlemiss, Alan Naylor, Martin Wills	1989	15
18	Photochemistry of ethenobenzocycloheptenones Tetrahedron ·Alfred Häßner, David Middlemiss, Judith Murray‐Rust, Peter Murray‐Rust	1982	7
19	1-Phenyl-2,3-diazacycl[3,2,2]azine, a new 10-π electron system. Involvement of 3,5-didehydroimidazo[1,5-a]pyridine? Tetrahedron Letters ·Diogo Wolf, David Middlemiss, Peter Murray‐Rust, Judith Murray‐Rust	1980	5
20	A direct method for the substitution of imidazo[1,5-a]pyridines at position 5 Tetrahedron Letters ·Diogo Wolf, David Middlemiss	1980	17

About David Middlemiss

David Middlemiss is a scholar working on Organic Chemistry, Pharmaceutical Science, Biochemistry, Inorganic Chemistry and Pharmacology, having authored 45 papers that have together received 993 indexed citations. Recurring topics across this work include Asymmetric Synthesis and Catalysis (10 papers), Receptor Mechanisms and Signaling (8 papers), Synthetic Organic Chemistry Methods (7 papers), Chemical synthesis and alkaloids (6 papers), Asymmetric Hydrogenation and Catalysis (5 papers), Catalytic Cross-Coupling Reactions (4 papers), Neuropeptides and Animal Physiology (4 papers) and Chemical Synthesis and Analysis (4 papers). The work is most often cited by research in Organic Chemistry (624 citations), Inorganic Chemistry (119 citations), Cellular and Molecular Neuroscience (117 citations), Molecular Biology (337 citations) and Cardiology and Cardiovascular Medicine (102 citations). David Middlemiss has collaborated with scholars based in United Kingdom, Australia and New Zealand. Frequent co-authors include William J. Kerr, Stephen G. Davies, Alan Naylor, Steve P. Watson, Steven J. Coote, Joseph P. A. Harrity, Duncan B. Judd, Barry C. Ross, Anthony Dean and Nicholas Bailey. Their work appears in journals such as Tetrahedron Letters, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Tetrahedron and Journal of Organometallic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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