David Loakes

2.8k total citations · 1 hit paper
73 papers, 2.2k citations indexed

About

David Loakes is a scholar working on Molecular Biology, Organic Chemistry and Infectious Diseases. According to data from OpenAlex, David Loakes has authored 73 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 55 papers in Molecular Biology, 23 papers in Organic Chemistry and 16 papers in Infectious Diseases. Recurrent topics in David Loakes's work include DNA and Nucleic Acid Chemistry (29 papers), HIV/AIDS drug development and treatment (16 papers) and RNA and protein synthesis mechanisms (14 papers). David Loakes is often cited by papers focused on DNA and Nucleic Acid Chemistry (29 papers), HIV/AIDS drug development and treatment (16 papers) and RNA and protein synthesis mechanisms (14 papers). David Loakes collaborates with scholars based in United Kingdom, Japan and United States. David Loakes's co-authors include D. M. Brown, Philipp Holliger, V. Ramakrishnan, Ann C. Kelley, Albert Weixlbaumer, R.M. Voorhees, F. Hill, Kazuo Negishi, Alexandra Vaisman and Roger Woodgate and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nucleic Acids Research.

In The Last Decade

David Loakes

71 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

2009 292 citations R.M. Voorhees, Albert Weixlbaumer et al. Nature Structural & Molecular Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David Loakes United Kingdom	23	1.8k	303	288	220	190	73	2.2k
Richard E. Showalter United States	18	1.7k 0.9×	363 1.2×	217 0.8×	140 0.6×	118 0.6×	29	2.1k
Amechand Boodhoo Canada	14	1.1k 0.6×	249 0.8×	155 0.5×	111 0.5×	310 1.6×	17	2.0k
Dev P. Arya United States	34	2.5k 1.4×	134 0.4×	537 1.9×	220 1.0×	216 1.1×	96	3.0k
Bruce E. Kaplan United States	23	1.8k 1.0×	288 1.0×	199 0.7×	114 0.5×	131 0.7×	29	2.2k
K. Muniyappa India	34	2.7k 1.5×	817 2.7×	216 0.8×	264 1.2×	235 1.2×	128	3.2k
Nickolay Y. Chirgadze United States	24	1.2k 0.6×	244 0.8×	443 1.5×	120 0.5×	241 1.3×	38	2.0k
Howard Gamper United States	33	3.6k 2.0×	610 2.0×	374 1.3×	199 0.9×	84 0.4×	98	4.1k
Angelo Gunasekera United States	21	1.8k 1.0×	426 1.4×	93 0.3×	100 0.5×	289 1.5×	28	2.3k
Leonid Beigelman United States	27	1.8k 1.0×	107 0.4×	245 0.9×	133 0.6×	252 1.3×	100	2.3k
Joseph E. Wedekind United States	33	2.6k 1.5×	387 1.3×	110 0.4×	113 0.5×	342 1.8×	90	3.3k

Countries citing papers authored by David Loakes

Since Specialization

Citations

This map shows the geographic impact of David Loakes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Loakes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Loakes more than expected).

Fields of papers citing papers by David Loakes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Loakes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Loakes. The network helps show where David Loakes may publish in the future.

Co-authorship network of co-authors of David Loakes

This figure shows the co-authorship network connecting the top 25 collaborators of David Loakes. A scholar is included among the top collaborators of David Loakes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Loakes. David Loakes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Loakes, David & Philipp Holliger. (2009). Darwinian chemistry: towards the synthesis of a simple cell. Molecular BioSystems. 5(7). 686–694. 18 indexed citations

Loakes, David & Philipp Holliger. (2009). Polymerase engineering: towards the encoded synthesis of unnatural biopolymers. Chemical Communications. 4619–4619. 68 indexed citations

Voorhees, R.M., Albert Weixlbaumer, David Loakes, Ann C. Kelley, & V. Ramakrishnan. (2009). Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome. Nature Structural & Molecular Biology. 16(5). 528–533. 292 indexed citations breakdown →

Okamoto, Keinosuke, Sakae Arimoto, David Loakes, et al.. (2008). Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 640(1-2). 107–112. 8 indexed citations

Yamamoto, Junpei, David Loakes, Chikahide Masutani, et al.. (2008). Translesion synthesis across the (6-4) photoproduct and its Dewar valence isomer by the Y-family and engineered DNA polymerases. Nucleic Acids Symposium Series. 52(1). 339–340. 6 indexed citations

Yung, Cathleen M., Tetsuya Suzuki, Yoshinaga Okugawa, et al.. (2007). Nucleotide incorporation against 7,8-dihydro-8-oxoguanine is influenced by neighboring base sequences in TLS DNA polymerase reaction. Nucleic Acids Symposium Series. 51(1). 49–50. 6 indexed citations

Gallego, José & David Loakes. (2007). Solution structure and dynamics of DNA duplexes containing the universal base analogues 5-nitroindole and 5-nitroindole 3-carboxamide. Nucleic Acids Research. 35(9). 2904–2912. 20 indexed citations

Brown, D. M., et al.. (2007). Anti-malarial activity of N6-modified purine analogues. Bioorganic & Medicinal Chemistry. 15(16). 5551–5562. 27 indexed citations

Suzuki, Tetsuya, et al.. (2005). Mutagenic properties of ribonucleotide analogues in reverse transcription with HIV and AMV reverse transcriptases. Nucleic Acids Symposium Series. 49(1). 97–98. 1 indexed citations

10.

Iwai, Shigenori, et al.. (2005). Roles of the polymerase and BRCT domains of Rev1 protein in translesion DNA synthesis in yeast in vivo. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 578(1-2). 79–87. 44 indexed citations

11.

Ghadessy, Farid J., Nicola Ramsay, François Boudsocq, et al.. (2004). Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. Nature Biotechnology. 22(6). 755–759. 136 indexed citations

12.

Kobayashi, Keita, K. Moriyama, Shigenori Iwai, et al.. (2002). Use of yeast transformation by oligonucleotides to study DNA lesion bypass in vivo. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 502(1-2). 53–60. 20 indexed citations

13.

Negishi, Kazuo, David Loakes, Leroy Worth, et al.. (2001). Binding specificities of the mismatch binding protein, MutS, to oligonucleotides containing modified bases. Nucleic Acids Symposium Series. 1(1). 221–222. 2 indexed citations

14.

Smith, Cassandra L., Adrian C. Simmonds, A. Hamilton, et al.. (1998). DNA Polymerase Incorporation of Universal Base Triphosphates. Nucleosides and Nucleotides. 17(1-3). 541–554. 18 indexed citations

15.

Meervelt, Luc Van, David Loakes, D. M. Brown, et al.. (1998). A thymine-like base analogue forms wobble pairs with adenine in a Z-DNA duplex. Journal of Molecular Biology. 282(5). 1005–1011. 11 indexed citations

16.

Ball, Sarah, et al.. (1998). The use of tailed octamer primers for cycle sequencing. Nucleic Acids Research. 26(22). 5225–5227. 17 indexed citations

17.

Loakes, David, F. Hill, D. M. Brown, & Stephen A. Salisbury. (1997). Stability and structure of DNA oligonucleotides containing non-specific base analogues. Journal of Molecular Biology. 270(3). 426–435. 40 indexed citations

18.

Suzuki, Miki, David Loakes, & Naoto Yagi. (1996). DNA conformation and its changes upon binding transcription factors. Advances in Biophysics. 32. 53–72. 6 indexed citations

19.

Loakes, David, et al.. (1995). 3-Nitropyrrole and 5-nitroindole as universal bases in primers for DNA sequencing and PCR. Nucleic Acids Research. 23(13). 2361–2366. 78 indexed citations

20.

Loakes, David & D. M. Brown. (1994). 5-Nitroindole as an universal base analogue. Nucleic Acids Research. 22(20). 4039–4043. 128 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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