David L. Akey

2.2k citations

31 papers · 1.7k indexed · 1 hit paper · h-index 22

Molecular Biology top 10%
Public Health, Environmental and Occupational Health top 5%
Infectious Diseases top 5%
Pharmacology top 2%
Materials Chemistry

Co-authors: Janet L. Smith William Clay Brown Jamie R. Konwerski David H. Sherman Richard Kühn Georgios Skiniotis Joyce Jose V.N. Malashkevich
Topics: Microbial Natural Products and Biosynthesis (12 papers)Mosquito-borne diseases and control (6 papers)Genomics and Phylogenetic Studies (4 papers)
Cited by: Infectious Diseases Pharmacology Public Health, Environmental and Occupational Health
Journals: Science Journal of the American Chemical Society Journal of Biological Chemistry
Partner nations: United States Japan South Korea

In The Last Decade

David L. Akey

31 papers receiving 1.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune System

2014 327 citations David L. Akey, William Clay Brown et al. Science profile →

Peers

Countries citing papers authored by David L. Akey

Since Specialization

Citations

This map shows the geographic impact of David L. Akey's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David L. Akey with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David L. Akey more than expected).

Fields of papers citing papers by David L. Akey

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David L. Akey. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David L. Akey. The network helps show where David L. Akey may publish in the future.

Co-authorship network of co-authors of David L. Akey

This figure shows the co-authorship network connecting the top 25 collaborators of David L. Akey. A scholar is included among the top collaborators of David L. Akey based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David L. Akey. David L. Akey is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction 2021 ·Science ·Scott B. Biering,David L. Akey,Marcus P. Wong,William Clay Brown,(unknown),Henry Puerta‐Guardo,Francielle Tramontini Gomes de Sousa,Chunling Wang,Jamie R. Konwerski,Diego A. Espinosa,(unknown),Dustin R. Glasner,(unknown),Sophie F. Blanc,(unknown),Stephen J. Elledge,Michael J. Mina,P. Robert Beatty,Janet L. Smith,Eva Harris	99
2	Thiosulfate sulfurtransferase-like domain–containing 1 protein interacts with thioredoxin 2018 ·Journal of Biological Chemistry ·Marouane Libiad,Nicole Motl,David L. Akey,Naoya Sakamoto,Eric R. Fearon,Janet L. Smith,Ruma Banerjee	44
3	Efficient merging of data from multiple samples for determination of anomalous substructure 2016 ·Acta Crystallographica Section D Structural Biology ·David L. Akey,Thomas C. Terwilliger,Janet L. Smith	14
4	Extended surface for membrane association in Zika virus NS1 structure 2016 ·Nature Structural & Molecular Biology ·William Clay Brown,David L. Akey,Jamie R. Konwerski,Jeffrey Tarrasch,Georgios Skiniotis,Richard Kühn,Janet L. Smith	134
5	Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing 2016 ·Acta Crystallographica Section D Structural Biology ·Thomas C. Terwilliger,G. Bunkóczi,Li‐Wei Hung,Peter H. Zwart,Janet L. Smith,David L. Akey,Paul D. Adams	24
6	Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal 2016 ·Acta Crystallographica Section D Structural Biology ·Thomas C. Terwilliger,G. Bunkóczi,Li‐Wei Hung,Peter H. Zwart,Janet L. Smith,David L. Akey,Paul D. Adams	21
7	Flavivirus NS1 Structures Reveal Surfaces for Associations with Membranes and the Immune Systembreakdown → 2014 ·Science ·David L. Akey,William Clay Brown,Somnath Dutta,Jamie R. Konwerski,Joyce Jose,(unknown),James Delproposto,Craig M. Ogata,Georgios Skiniotis,Richard Kühn,Janet L. Smith	327
8	Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor 2012 ·Journal of the American Chemical Society ·Joseph A. Chemler,Tonia J. Buchholz,Todd W. Geders,David L. Akey,Christopher M. Rath,George E. Chlipala,Janet L. Smith,David H. Sherman	43
9	Insights from the sea: Structural biology of marine polyketide synthases 2012 ·Natural Product Reports ·David L. Akey,(unknown),Dheeraj Khare,Janet L. Smith	20
10	The oligomeric state of CtBP determines its role as a transcriptional co‐activator and co‐repressor of Wingless targets 2011 ·The EMBO Journal ·Chandan Bhambhani,(unknown),David L. Akey,Ken M. Cadigan	57
11	A New Structural Form in the SAM/Metal-Dependent O‑Methyltransferase Family: MycE from the Mycinamicin Biosynthetic Pathway 2011 ·Journal of Molecular Biology ·David L. Akey,Shengying Li,Jamie R. Konwerski,(unknown),Steffen M. Bernard,Yojiro Anzai,Fumio Kato,David H. Sherman,Janet L. Smith	21
12	A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteins 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),David L. Akey,Janet L. Smith,Robert Fecik	2
13	Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase 2010 ·Angewandte Chemie International Edition ·Jamie B. Scaglione,David L. Akey,(unknown),Jeffrey D. Kittendorf,Christopher M. Rath,(unknown),Janet L. Smith,David H. Sherman	45
14	Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway 2008 ·Journal of Biological Chemistry ·(unknown),David L. Akey,Monica K. Silver,Suzanne J. Admiraal,Janet L. Smith	63
15	A 7 µm mini-beam improves diffraction data from small or imperfect crystals of macromolecules 2008 ·Acta Crystallographica Section D Biological Crystallography ·Ruslan Sanishvili,Nagarajan Venugopalan,Derek W. Yoder,Michael E. Becker,Shenglan Xu,Stephen Corcoran,David L. Akey,Janet L. Smith,Robert F. Fischetti	49
16	Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels 2006 ·Nature Chemical Biology ·J. Giraldes,David L. Akey,Jeffrey D. Kittendorf,David H. Sherman,Janet L. Smith,Robert Fecik	73
17	Structural basis for macrolactonization by the pikromycin thioesterase 2006 ·Nature Chemical Biology ·David L. Akey,Jeffrey D. Kittendorf,J. Giraldes,Robert Fecik,David H. Sherman,Janet L. Smith	96
18	Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 Å 2005 ·Protein Science ·David L. Akey,James M. Berger	27
19	The MukF subunit of Escherichia coli condensin: architecture and functional relationship to kleisins 2005 ·The EMBO Journal ·(unknown),Scott Gradia,David L. Akey,James M. Berger	61
20	Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis 2004 ·Nature Structural & Molecular Biology ·Joseph D. Mougous,Christopher J. Petzold,Ryan H. Senaratne,Dong Hoon Lee,David L. Akey,Fiona L. Lin,Sarah Munchel,Matthew R. Pratt,Lee W. Riley,Julie A. Leary,James M. Berger,Carolyn R. Bertozzi	83

About David L. Akey

David L. Akey is a scholar working on Pharmacology, Biotechnology and Pharmacology, having authored 31 papers that have together received 1.7k indexed citations. Recurring topics across this work include Microbial Natural Products and Biosynthesis (12 papers), Mosquito-borne diseases and control (6 papers) and Genomics and Phylogenetic Studies (4 papers). The work is most often cited by research in Infectious Diseases (485 citations), Pharmacology (427 citations) and Public Health, Environmental and Occupational Health (580 citations). David L. Akey has collaborated with scholars based in United States, Japan and South Korea. Frequent co-authors include Janet L. Smith, William Clay Brown, Jamie R. Konwerski, David H. Sherman, Richard Kühn, Georgios Skiniotis, Joyce Jose, V.N. Malashkevich, Peter S. Kim and Craig M. Ogata. Their work appears in journals such as Science, Journal of the American Chemical Society and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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