David J. Singel

16.2k citations

93 papers · 13.2k indexed · 7 hit papers · h-index 37

Impact in

Biophysics top 0.05%
- Electron Spin Resonance Studies
Biochemistry top 0.05%
- Sulfur Compounds in Biology
- Eicosanoids and Hypertension Pharmacology

Papers in

Biophysics 34
- Electron Spin Resonance Studies 33
Endocrine and Autonomic Systems 12
- Neuroscience of respiration and sleep 12

Co-authors: Jonathan S. Stamler Joseph Loscalzo Mark E. Mullins Daniel I. Simon John A. Osborne Stuart A. Lipton Zhuo‐Hua Pan Huei‐Sheng Vincent Chen
Journals: Proceedings of the National Academy of Sciences (12 papers)The Journal of Chemical Physics (12 papers)Journal of the American Chemical Society (7 papers)The Journal of Physical Chemistry (6 papers)Chemical Physics Letters (5 papers)
Partner nations: United States Netherlands France

In The Last Decade

David J. Singel

93 papers receiving 12.8k citations

Hit Papers

7 papers align trajectories log scale

Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. 1993 · 730 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1993 Journal of Clinical Investigation
1993 Physical Review Letters
1993 Proceedings of the National Academy of Sciences
1993 Nature
1992 Proceedings of the National Academy of Sciences
1992 Science
1992 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by David J. Singel

Since Specialization

Citations

This map shows the geographic impact of David J. Singel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David J. Singel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David J. Singel more than expected).

Fields of papers citing papers by David J. Singel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David J. Singel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David J. Singel. The network helps show where David J. Singel may publish in the future.

Co-authors

The 25 scholars most cited alongside David J. Singel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David J. Singel Line = papers co-authored together David J. Singel links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine Molecular Aspects of Medicine ·Richard T. Premont, David J. Singel, Jonathan S. Stamler	2021	13
2	The Quantum Biology of Reactive Oxygen Species Partitioning Impacts Cellular Bioenergetics Scientific Reports ·Robert J. Usselman, Eglė Vilkelytė, Pablo R. Castello, 梶木美樹, Thorsten Ritz, Edward A. Dratz, David J. Singel, Carlos F. Martino	2016	86
3	Spin Biochemistry Modulates Reactive Oxygen Species (ROS) Production by Radio Frequency Magnetic Fields PLoS ONE ·Robert J. Usselman, E Jaiyeoba Babatunde, David J. Singel, Carlos F. Martino	2014	92
4	Selective trapping of SNO-BSA and GSNO by benzenesulfinic acid sodium salt: mechanistic study of thiosulfonate formation and feasibility as a protein S-nitrosothiol detection strategy Tetrahedron Letters ·Benjamin D. Reeves, Jonathan K. Hilmer, Leyi Li, K Cordova, Gerhard Laun, Keith Johnson, Ursula Zinth, David J. Singel, Paul A. Grieco	2013	12
5	EPR Characterization of Heterogeneously Functionalized Dendrimers Macromolecules ·Georgina Curto, Karl B. Sebby, David J. Singel, Mary J. Cloninger	2007	15
6	Assessments of the chemistry and vasodilatory activity of nitrite with hemoglobin under physiologically relevant conditions Journal of Inorganic Biochemistry ·K Hoehnscheid, María de los Milagros Pierini, Yan Yun, Elizabeth M. Williams, Jonathan S. Stamler, David J. Singel	2005	75
7	EPR and affinity studies of mannose–TEMPO functionalized PAMAM dendrimers Organic & Biomolecular Chemistry ·Audrey Fogels, Karl B. Sebby, Éric Walter, David J. Singel, Mary J. Cloninger	2004	15
8	Reply to "NO adducts in mammalian red blood cells: too much or too little?" Nature Medicine ·Jonathan S. Stamler, Douglas T. Hess, David J. Singel	2003	8
9	Nitric oxide in the human respiratory cycle Nature Medicine ·T. McMahon, Richard E. Moon, Connie Dang, Martha Sue Carraway, Begum Mahfuj Ara, Bryant W. Stolp, Andrew J. Gow, John R. Pawloski, Simona Giribone, David J. Singel, Claude A. Piantadosi, Jonathan S. Stamler	2002	363
10	Functional Coupling of Oxygen Binding and Vasoactivity inS-Nitrosohemoglobin Journal of Biological Chemistry ·T. McMahon, Begum Mahfuj Ara, Joseph Bonaventura, David J. Singel, Jonathan S. Stamler	2000	114
11	Nitroxide Side-Chain Dynamics in a Spin-Labeled Helix-Forming Peptide Revealed by High-Frequency (139.5-GHz) EPR Spectroscopy Journal of Magnetic Resonance ·Marina Bennati, Gary J. Gerfen, Gary V. Martinez, Robert G. Griffin, David J. Singel, Glenn L. Millhauser	1999	16
12	The Effects of Cryoprotection on the Structure and Activity of p21ras:Implications for Electron Spin-Echo Envelope Modulation Spectroscopy Journal of Magnetic Resonance ·Christopher J. Halkides, Christian T. Farrar, David J. Singel	1998	11
13	The frozen solution structure of p21 ras determined by ESEEM spectroscopy reveals weak coordination of Thr35 to the active site metal ion Structure ·Christian T. Farrar, Christopher J. Halkides, David J. Singel	1997	16
14	Characterization of the Active Site of p21 ras by Electron Spin-Echo Envelope Modulation Spectroscopy with Selective Labeling: Comparisons between GDP and GTP Forms Biochemistry ·Christopher J. Halkides, Christian T. Farrar, Russell G. Larsen, Alfred G. Redfield, David J. Singel	1994	26
15	Chapter 29 Nitric oxide in the central nervous system Progress in brain research ·Stuart A. Lipton, David J. Singel, Jonathan S. Stamler	1994	76
16	Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. Journal of Clinical Investigation ·Jonathan S. Stamler, John A. Osborne, สุพักตรา สุทธสุภา, LeRoy E. Rabbani, Mark E. Mullins, David J. Singel, Joseph Loscalzo Hit paper breakdown →	1993	730
17	A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds Nature ·Stuart A. Lipton, Yun‐Beom Choi, Zhuo‐Hua Pan, LI Song-ling, Huei‐Sheng Vincent Chen, Nikolaus J. Sucher, Joseph Loscalzo, David J. Singel, Jonathan S. Stamler Hit paper breakdown →	1993	2080
18	Peroxynitrite-induced rat colitis—A new model of colonic inflammation Gastroenterology ·Daniel Rachmilewitz, Jonathan S. Stamler, Fanny Karmeli, Mark E. Mullins, David J. Singel, J Loscalzo, Ramnik J. Xavier, Daniel K. Podolsky	1993	232
19	Double electron–electron resonance spin–echo modulation: Spectroscopic measurement of electron spin pair separations in orientationally disordered solids The Journal of Chemical Physics ·Russell G. Larsen, David J. Singel	1993	213
20	Electron nuclear double resonance spectroscopy of a hen egg-white lysozyme--Cu2+ complex in tetragonal single crystals. Proceedings of the National Academy of Sciences ·Clyde A. Hutchison, David J. Singel	1981	3

About David J. Singel

David J. Singel is a scholar working on Biophysics, Endocrine and Autonomic Systems, Biochemistry, Spectroscopy and Ceramics and Composites, having authored 93 papers that have together received 13.2k indexed citations. Recurring topics across this work include Electron Spin Resonance Studies (33 papers), Nitric Oxide and Endothelin Effects (27 papers), Advanced NMR Techniques and Applications (19 papers), Hemoglobin structure and function (19 papers), Neuroscience of respiration and sleep (12 papers), Solid-state spectroscopy and crystallography (9 papers), Spectroscopy and Quantum Chemical Studies (8 papers) and Glass properties and applications (7 papers). The work is most often cited by research in Biophysics (1.8k citations), Biochemistry (2.0k citations), Physiology (6.7k citations), Endocrine and Autonomic Systems (1.4k citations) and Cell Biology (1.6k citations). David J. Singel has collaborated with scholars based in United States, Netherlands and France. Frequent co-authors include Jonathan S. Stamler, Joseph Loscalzo, Mark E. Mullins, Daniel I. Simon, John A. Osborne, Stuart A. Lipton, Zhuo‐Hua Pan, Huei‐Sheng Vincent Chen, Yun‐Beom Choi and Nikolaus J. Sucher. Their work appears in journals such as Proceedings of the National Academy of Sciences, The Journal of Chemical Physics, Journal of the American Chemical Society, The Journal of Physical Chemistry and Chemical Physics Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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