David Iles

2.5k citations

42 papers · 1.9k indexed · h-index 19

Impact in

Reproductive Medicine top 2%
- Sperm and Testicular Function
Endocrine and Autonomic Systems top 5%
- Neuroscience of respiration and sleep

Papers in ⓘ

Molecular Biology 31
- Ion channel regulation and function 20
- Genomics and Chromatin Dynamics 5
- Epigenetics and DNA Methylation 4
Genetics 10
- Animal Genetics and Reproduction 4

Co-authors: David Miller (11 shared papers)Martin H. Brinkworth (5 shared papers)Chris Peers (5 shared papers)Helen S. Mason (4 shared papers)Paul J. Kemp (5 shared papers)Daniela Riccardi (3 shared papers)Jonathan Bould (1 shared paper)Philip M. Hopkins (9 shared papers)
Journals: Reproduction (4 papers)British Journal of Anaesthesia (3 papers)Annals of Human Genetics (2 papers)Systems Biology in Reproductive Medicine (2 papers)Genomics (2 papers)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

David Iles

42 papers receiving 1.9k citations

Peers

Countries citing papers authored by David Iles

Since Specialization

Citations

This map shows the geographic impact of David Iles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Iles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Iles more than expected).

Fields of papers citing papers by David Iles

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Iles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Iles. The network helps show where David Iles may publish in the future.

Co-authors

The 25 scholars most cited alongside David Iles, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Iles Line = papers co-authored together David Iles links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 42 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Hemoxygenase-2 Is an Oxygen Sensor for a Calcium-Sensitive Potassium Channel Science ·Sandile E. J. Williams, Phillippa Wootton, Helen S. Mason, Jonathan Bould, David Iles, Daniela Riccardi, Chris Peers, Paul J. Kemp	2004	370
2	Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics Reproduction ·David Miller, Martin H. Brinkworth, David Iles	2009	297
3	Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences Genome Research ·Ali Arpanahi, Martin H. Brinkworth, David Iles, Stephen A. Krawetz, Agnieszka Paradowska‐Gorycka, Adrian E. Platts, Myriam Saida, Klaus Steger, Philip Tedder, David Miller	2009	217
4	Localization of the gene encoding the α₂/δ-subunits of the L-type voltage-dependent calcium channel to chromosome 7q and analysis of the segregation of flanking markers in malignant hyperthermia susceptible families Human Molecular Genetics ·David Iles, F. Lehmann‐Horn, Stephen W. Scherer, L.-C. Tsui, D.Olde Weghuis, R.F. Suijkerbuijk, Luc Heytens, Gábor Mikala, Arnold Schwartz, F.R. ELLIS, A. Stewart, Thomas Deufel, B. Wieringa	1994	126
5	Characterization of the myotonic dystrophy region predicts multiple protein isoform–encoding mRNAs Nature Genetics ·Gert Jansen, Mani S. Mahadevan, Chris T. Amemiya, Nicole G.M. Wormskamp, Bart Segers, Wiljan Hendriks, Kim O'Hoy, Stephen Baird, Luc A. Sabourin, Greg Lennon, P.L. Jap, David Iles, M. Coerwinkel, Marten H. Hofker, A.V. Carrano, Peter J. de Jong, R. G. Korneluk, B. Wieringa	1992	121
6	Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart. Proceedings of the National Academy of Sciences ·D. Schultz, Gábor Mikala, Atsuko Yatani, Dorothy Engle, David Iles, Bart Segers, Richard J. Sinke, D. Olde Weghuis, Udo Klöckner, Minoru Wakamori	1993	116
7	Genetic variation in RYR1 and malignant hyperthermia phenotypes British Journal of Anaesthesia ·Danielle Carpenter, Rachel L. Robinson, Rupert J. Quinnell, Christopher Ringrose, Marion C. Hogg, F. Casson, Patrick Booms, David Iles, P.J. Halsall, Derek S. Steele, Marie Shaw, Philip M. Hopkins	2009	81
8	The human ryanodine receptor gene: its mapping to 19q13.1, placement in a chromosome 19 linkage group, and exclusion as the gene causing myotonic dystrophy. PubMed ·A E MacKenzie, Robert G. Korneluk, Francesco Zorzato, Junichi Fujii, Michael J. Phillips, David Iles, Bé Wieringa, S. Leblond, J Bailly, H.F. Willard	1990	61
9	Evidence for genetic heterogeneity of malignant hyperthermia susceptibility. PubMed ·Thomas Deufel, Astrid Golla, David Iles, Alfons Meindl, Thomas Meitinger, Dirk Schindelhauer, ArthurL. DeVries, D. Pongratz, D H MacLennan, Keith Johnson	1992	60
10	Multiple interacting gene products may influence susceptibility to malignant hyperthermia. PubMed ·Rachel L. Robinson, Julie Curran, F.R. ELLIS, P.J. Halsall, William J. Hall, Philip M. Hopkins, David Iles, Sarah P. West, M.‐A. Shaw	2000	51
11	Multiple interacting gene products may influence susceptibility to malignant hyperthermia Annals of Human Genetics ·Rachel L. Robinson, Justin Curran, F.R. ELLIS, P.J. Halsall, W. J. HALL, Philip M. Hopkins, David Iles, S. P. WEST, M.‐A. Shaw	2000	46
12	The impact of maternal age on gene expression during the GV to MII transition in euploid human oocytes Human Reproduction ·Panagiotis Ntostis, David Iles, Georgia Kokkali, T. Vaxevanoglou, Emmanuel Kanavakis, Agni Pantou, John Huntriss, Konstantinos Pantos, Helen M. Picton	2021	40
13	Refined genetic localization for central core disease. PubMed ·John C. Mulley, H.M. Kozman, Hilary A. Phillips, Ági K. Gedeon, JillA. McCure, David Iles, Ronald G. Gregg, Kirk J. Hogan, Fergus J. Couch, D H MacLennan	1993	38
14	Properties of three COOH-terminal splice variants of a human cardiac L-type Ca2+-channel alpha1-subunit American Journal of Physiology-Heart and Circulatory Physiology ·Udo Klöckner, Gábor Mikala, Jörg Eisfeld, David Iles, Mark Strobeck, John L. Mershon, Arnold Schwartz, Gyula Váradi	1997	31
15	The G1021A substitution in the RYR1 gene does not cosegregate with malignant hyperthermia susceptibility in a British pedigree. PubMed ·A M Adeokun, Sarah P. West, F.R. ELLIS, P.J. Halsall, Philip M. Hopkins, Ali Mohammad Foroughmand, David Iles, Rachel L. Robinson, A. Stewart, Julie Curran	1997	28
16	Segregation of malignant hyperthermia, central core disease and chromosome 19 markers British Journal of Anaesthesia ·Julie Curran, William J. Hall, P.J. Halsall, Philip M. Hopkins, David Iles, Alex Markham, Samuel McCall, Rachel L. Robinson, Sarah P. West, Leslie Bridges, F.R. ELLIS	1999	22
17	Potential sperm contributions to the murine zygote predicted by in silico analysis Reproduction ·Panagiotis Ntostis, Deborah Carter, David Iles, John Huntriss, Maria Tzetis, David Miller	2017	22
18	High-resolution physical mapping of four microsatellite repeat markers near the RYR1 locus on chromosome 19q13.1 and apparent exclusion of the MHS locus from this region in two malignant hyperthermia susceptible families Genomics ·David Iles, Bart Segers, Luc Heytens, R. C. A. Sengers, Bé Wieringa	1992	21
19	A RYR1 mutation associated with recessive congenital myopathy and dominant malignant hyperthermia in Asian families Muscle & Nerve ·Danielle Carpenter, Azzam Ismail, Rachel L. Robinson, Christopher Ringrose, Patrick Booms, David Iles, P.J. Halsall, Derek S. Steele, Marie‐Anne Shaw, Philip M. Hopkins	2009	18
20	Can trophectoderm RNA analysis predict human blastocyst competency? Systems Biology in Reproductive Medicine ·Panagiotis Ntostis, Georgia Kokkali, David Iles, John Huntriss, Maria Tzetis, Helen M. Picton, Konstantinos Pantos, David Miller	2019	15

About David Iles

David Iles is a scholar working on Molecular Biology, Genetics, Cardiology and Cardiovascular Medicine, Cellular and Molecular Neuroscience and Public Health, Environmental and Occupational Health, having authored 42 papers that have together received 1.9k indexed citations. Recurring topics across this work include Ion channel regulation and function (20 papers), Cardiac electrophysiology and arrhythmias (8 papers), Genomics and Chromatin Dynamics (5 papers), Genetic Neurodegenerative Diseases (5 papers), Reproductive Biology and Fertility (5 papers), Animal Genetics and Reproduction (4 papers), Epigenetics and DNA Methylation (4 papers) and Neuroscience of respiration and sleep (4 papers). The work is most often cited by research in Reproductive Medicine (331 citations), Endocrine and Autonomic Systems (172 citations), Cardiology and Cardiovascular Medicine (540 citations), Molecular Biology (1.4k citations) and Cellular and Molecular Neuroscience (375 citations). David Iles has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include David Miller, Martin H. Brinkworth, Chris Peers, Helen S. Mason, Paul J. Kemp, Daniela Riccardi, Jonathan Bould, Philip M. Hopkins, P.J. Halsall and Rachel L. Robinson. Their work appears in journals such as Reproduction, British Journal of Anaesthesia, Annals of Human Genetics, Systems Biology in Reproductive Medicine and Genomics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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