David Gius

17.2k citations

148 papers · 13.7k indexed · 6 hit papers · h-index 65

Geriatrics and Gerontology top 0.02%
- Sirtuins and Resveratrol in Medicine 40
Cancer Research top 0.5%
Aging top 0.5%
Physiology top 0.2%
- Adipose Tissue and Metabolism 16
Molecular Biology top 0.5%
- Mitochondrial Function and Pathology 21
- Redox biology and oxidative stress 20
- Genomics, phytochemicals, and oxidative stress 13
- Glutathione Transferases and Polymorphisms 13
- Epigenetics and DNA Methylation 13
Epidemiology
- Autophagy in Disease and Therapy 20

Co-authors: Douglas R. Spitz Seong‐Hoon Park Athanassios Vassilopoulos Özkan Özden Kheem S. Bisht Jian Jian Li J. Daniel Pennington Chu‐Xia Deng
Cited by: Geriatrics and Gerontology Cancer Research Aging
Journals: Cancer Research (9 papers)Free Radical Biology and Medicine (9 papers)Journal of Biological Chemistry (8 papers)
Partner nations: United States South Korea Japan

In The Last Decade

David Gius

146 papers receiving 13.5k citations

Hit Papers

6 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2015 Nature Communications
2013 Science
2010 Molecular Cell
2010 Cancer Cell
2008 Nature
2004 Cancer and Metastasis Reviews

Peers

Countries citing papers authored by David Gius

Since Specialization

Citations

This map shows the geographic impact of David Gius's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Gius with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Gius more than expected).

Fields of papers citing papers by David Gius

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Gius. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Gius. The network helps show where David Gius may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David Gius, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Gius Line = papers co-authored together David Gius links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered liver lipid metabolism on a ketogenic diet Free Radical Biology and Medicine ·Guogang Xu,Yulia Richard,Ysaac Maclee Suaña Bellido,Yucheng Gao,Sung‐Jen Wei,Meixia Pan,Xianlin Han,Guiming Li,Daohong Zhou,Haiyan Jiang,Yada Sriwithurn,Erin Munkácsy,Nobuo Horikoshi,David Gius	2025	2
2	Manganese Superoxide Dismutase Acetylation and Regulation of Protein Structure in Breast Cancer Biology and Therapy Antioxidants ·Philip M. Marsh,Н. В. Нарский,Yulia Richard,Debopriya Mondal,Nobuo Horikoshi,David Gius	2022	7
3	MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism International Journal of Biological Sciences ·Yucheng Gao,Yueming Zhu,Laura M. Gambino,Dheani Nur Ahadya Syifa Chaerunissa,Agustín Basterrechea,Knut Ola Naastad Strøm,David Gius	2021	12
4	An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth Proceedings of the National Academy of Sciences ·George Jithin Babu,Greg L. Beilhartz,Du Yansheng,Marco Biancucci,Sergio Valentini,David Gius,Roman A. Melnyk,K.J.F. Satchell	2020	28
5	SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer Proceedings of the National Academy of Sciences ·Chenxia He,Jeanne M. Danes,Peter C. Hart,Yueming Zhu,Yunping Huang,V Olker N Ickeleit,Joseph O’Brien,Angela Mathison,Binwu Tang,Jonna Frasor,Lalage M. Wakefield,Douglas Ganini,Teresa Toranska,Jacek Zielonka,Benjamin N. Gantner,Raúl Urrutia,David Gius,Marcelo G. Bonini	2019	54
6	SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor Growth Cancer Research ·Xianghui Zou,Yueming Zhu,Seong‐Hoon Park,Guoxiang Liu,Joseph O’Brien,Haiyan Jiang,David Gius	2017	74
7	SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth Cancer Research ·Seong‐Hoon Park,Özkan Özden,Guoxiang Liu,Ha Yong Song,Yueming Zhu,Yufan Yan,Xianghui Zou,Mohamad Asri Seman,Haiyan Jiang,Daniel R. Principe,Ho-Hyun Kim,Meejeon Roh,Athanassios Vassilopoulos,David Gius	2016	105
8	CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance Molecular Cancer Therapeutics ·Rui Liu,Ming Fan,Demet Candas,Lili Qin,Xiaodi Zhang,Angela Eldridge,June X. Zou,Tieqiao Zhang,B. B. Bokarwadia,Cuihong Jin,José Eduardo Frías-Chimal,Julian Perks,I Etxebeste,Andrew Vaughan,豊賣野,David Gius,Jian Jian Li	2015	84
9	Superoxide Mediates Acute Liver Injury in Irradiated Mice Lacking Sirtuin 3 Antioxidants and Redox Signaling ·Mitchell C. Coleman,Alicia K. Olivier,Frédéric Le Clair,Kranti A. Mapuskar,Gaowei Mao,Sean M. Martin,Dennis P. Riley,David Gius,Douglas R. Spitz	2013	31
10	SIRT3 Deacetylates ATP Synthase F ₁ Complex Proteins in Response to Nutrient- and Exercise-Induced Stress Antioxidants and Redox Signaling ·Athanassios Vassilopoulos,J. Daniel Pennington,Þorkell Andrésson,David M. Rees,Allen D. Bosley,Ian M. Fearnley,Amy‐Joan L. Ham,Charles R. Flynn,Salisha Hill,Kristie L. Rose,Hyun‐Seok Kim,Chu‐Xia Deng,John E. Walker,David Gius	2013	144
11	Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells Oncogene ·Jian Wang,Paul Anderson,Weijia Luo,David Gius,Mi Ryung Roh,Sarki A. Abdulkadir	2011	70
12	DNA Methyltransferase 1 and 3B Activate BAG-1 Expression via Recruitment of CTCFL/BORIS and Modulation of Promoter Histone Methylation Cancer Research ·Lunching Sun,Lei Huang,Phuongmai Nguyen,Kheem S. Bisht,Gil Bar‐Sela,Allen S. Ho,C. Matthew Bradbury,Wenqiang Yu,Hengmi Cui,Sun-Min Lee,Jane B. Trepel,Andrew P. Feinberg,David Gius	2008	41
13	CTCFL/BORIS Is a Methylation-Independent DNA-Binding Protein That Preferentially Binds to the Paternal H19 Differentially Methylated Region Cancer Research ·Phuongmai Nguyen,Hengmi Cui,Kheem S. Bisht,Lunching Sun,Krish Patel,Richard S. Lee,Hiroyuki Kugoh,Mitsuo Oshimura,Andrew P. Feinberg,David Gius	2008	39
14	BAT3 and SET1A Form a Complex with CTCFL/BORIS To Modulate H3K4 Histone Dimethylation and Gene Expression Molecular and Cellular Biology ·Phuongmai Nguyen,Gil Bar‐Sela,Lunching Sun,Kheem S. Bisht,Hengmi Cui,Elise C. Kohn,Andrew P. Feinberg,David Gius	2008	79
15	Epigenetic silencing of tumour suppressor gene p15 by its antisense RNAbreakdown → Nature ·Wenqiang Yu,David Gius,Patrick Onyango,Kristi Muldoon‐Jacobs,Judith E. Karp,Andrew P. Feinberg,Hengmi Cui	2008	665
16	Profiling Microdissected Epithelium and Stroma to Model Genomic Signatures for Cervical Carcinogenesis Accommodating for Covariates Cancer Research ·David Gius,MA Lisha,Eric Y. Chuang,Sheng Feng,Phyllis C. Huettner,Loan Nguyen,C. Matthew Bradbury,Mark V. Mishra,Shuping Gao,Barbara M. Buttin,David E. Cohn,Matthew A. Powell,Neil S. Horowitz,Bradford P. Whitcomb,Janet S. Rader	2007	76
17	Inhibition of nuclear factor-κB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma International Journal of Radiation OncologyBiologyPhysics ·Carter Van Waes,Angela A. Chang,Peter F. Lebowitz,Colleen Druzgal,Zhong Chen,Yusri Elsayed,John B. Sunwoo,Susan F. Rudy,John C. Morris,James B. Mitchell,Kevin Camphausen,David Gius,Julian Adams,Edward A. Sausville,Barbara A. Conley	2005	93
18	Redox-Sensitive Signaling Factors and Antioxidants: How Tumor Cells Respond to Ionizing Radiation Journal of Nutrition ·David Gius	2004	19
19	A novel p53‐inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis‐inducing factor (AIF) FEBS Letters ·Yoichi Ohiro,Igor Garkavtsev,Shinichiro Kobayashi,K. R. Sreekumar,D N Kolmakov,Bryan Higashikubo,Shannon Duffy,Ryuji Higashikubo,Anny Usheva,David Gius,Nikolai Kley,Nobuo Horikoshi	2002	103
20	Thioredoxin reductase is a novel cytoplasmic signaling factor regulating radiation-induced AP-1 DNA-binding activity and gene expression via active cysteine residues Free Radical Biology and Medicine ·C. Matthew Bradbury,Douglas R. Spitz,David Gius	2001	1

About David Gius

David Gius is a scholar working on Geriatrics and Gerontology, Cancer Research and Molecular Biology, having authored 148 papers that have together received 13.7k indexed citations. Recurring topics across this work include Sirtuins and Resveratrol in Medicine (40 papers), Mitochondrial Function and Pathology (21 papers), Redox biology and oxidative stress (20 papers), Autophagy in Disease and Therapy (20 papers), Adipose Tissue and Metabolism (16 papers), Genomics, phytochemicals, and oxidative stress (13 papers), Glutathione Transferases and Polymorphisms (13 papers) and Epigenetics and DNA Methylation (13 papers). The work is most often cited by research in Geriatrics and Gerontology (3.4k citations), Cancer Research (2.6k citations) and Aging (288 citations). David Gius has collaborated with scholars based in United States, South Korea and Japan. Frequent co-authors include Douglas R. Spitz, Seong‐Hoon Park, Athanassios Vassilopoulos, Özkan Özden, Kheem S. Bisht, Jian Jian Li, J. Daniel Pennington, Chu‐Xia Deng, Edouard I. Azzam and Haiyan Jiang. Their work appears in journals such as Cancer Research, Free Radical Biology and Medicine, Journal of Biological Chemistry, International Journal of Radiation Oncology*Biology*Physics and Antioxidants and Redox Signaling.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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