David A. van Heel

26.6k citations

97 papers · 6.5k indexed · 2 hit papers · h-index 44

Gastroenterology top 0.1%
- Celiac Disease Research and Management 23
Immunology top 1%
- Immunodeficiency and Autoimmune Disorders 14
- Immune Response and Inflammation 8
Genetics top 0.5%
- Inflammatory Bowel Disease 30
- Genetic Associations and Epidemiology 11
- Digestive system and related health 9
Epidemiology top 2%
- Microscopic Colitis 12
Surgery top 2%
- Helicobacter pylori-related gastroenterology studies 18

Co-authors: Cisca Wijmenga Karen A. Hunt Derek P. Jewell Matthew A. Brown Graham Heap Miles Parkes Adrián Cortés Gosia Trynka
Cited by: Gastroenterology Immunology Genetics
Journals: New England Journal of Medicine (2 papers)The Lancet (1 paper)Nucleic Acids Research (1 paper)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

David A. van Heel

95 papers receiving 6.4k citations

Hit Papers

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Peers

Countries citing papers authored by David A. van Heel

Since Specialization

Citations

This map shows the geographic impact of David A. van Heel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David A. van Heel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David A. van Heel more than expected).

Fields of papers citing papers by David A. van Heel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David A. van Heel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David A. van Heel. The network helps show where David A. van Heel may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David A. van Heel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David A. van Heel Line = papers co-authored together David A. van Heel links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Widespread recessive effects on common diseases in a cohort of 44,000 British Pakistanis and Bangladeshis with high autozygosity The American Journal of Human Genetics ·Teng Hiang Heng,Klaudia Walter,Qin Huang,Juha Karjalainen,Mark J. Daly,Henrike Heyne,Daniel Malawsky,Georgios Kalantzis,Sarah Finer,David A. van Heel,Hilary C. Martin	2025	0
2	CYP2C19 Genotype Prevalence and Association With Recurrent Myocardial Infarction in British–South Asians Treated With Clopidogrel JACC Advances ·Emma Magavern,Benjamin M. Jacobs,Helen R. Warren,Gherardo Finocchiaro,Sarah Finer,David A. van Heel,Damian Smedley,Mark J. Caulfield	2023	13
3	A multi-ancestry polygenic risk score improves risk prediction for coronary artery diseasebreakdown → Nature Medicine ·Aniruddh P. Patel,Minxian Wang,Yunfeng Ruan,Satoshi Koyama,Shoa L. Clarke,Xiong Yang,Catherine Tcheandjieu,Saaket Agrawal,Akl C. Fahed,Patrick T. Ellinor,Philip S. Tsao,Yan V. Sun,Kelly Cho,Peter W.F. Wilson,Themistocles L. Assimes,David A. van Heel,Adam S. Butterworth,Krishna G. Aragam,Pradeep Natarajan,Amit V. Khera	2023	98
4	Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study PLoS Medicine ·Sam Hodgson,Qin Qin Huang,Neneh Sallah,Chris Griffiths,William G. Newman,Richard C. Trembath,John Wright,R Thomas Lumbers,Karoline Kuchenbaecker,David A. van Heel,Rohini Mathur,Hilary C. Martin,Sarah Finer	2022	33
5	Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals Nature Communications ·Qin Qin Huang,Neneh Sallah,Diana Dunca,Bhavi Trivedi,Karen A. Hunt,Sam Hodgson,Samuel A. Lambert,Elena Arciero,John Wright,Chris Griffiths,Richard C. Trembath,Harry Hemingway,Michael Inouye,Sarah Finer,David A. van Heel,R Thomas Lumbers,Hilary C. Martin,Karoline Kuchenbaecker	2022	34
6	Fine-scale population structure and demographic history of British Pakistanis Nature Communications ·Elena Arciero,Sufyan Abid Dogra,Daniel Malawsky,Massimo Mezzavilla,Theofanis Tsismentzoglou,Qin Qin Huang,Karen A. Hunt,Dan Mason,Saghira Malik Sharif,David A. van Heel,Eamonn Sheridan,John Wright,Neil Small,Shai Carmi,Mark M. Iles,Hilary C. Martin	2021	14
7	Evaluating drug targets through human loss-of-function genetic variation Figshare ·Eric Vallabh Minikel,Konrad J. Karczewski,Hilary C. Martin,Beryl B. Cummings,Nicola Whiffin,Daniel R. Rhodes,Jessica Alföldi,Richard C. Trembath,David A. van Heel,Mark J. Daly,(unknown),(unknown),(unknown),(unknown)	2020	92
8	A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care Alimentary Pharmacology & Therapeutics ·Seth A. Sharp,Samuel E. Jones,Robert Kimmitt,Michael N. Weedon,Anne Halpin,Andrew R. Wood,Robin N. Beaumont,Seema King,David A. van Heel,Patricia Campbell,William Hagopian,Justine Turner,Richard A. Oram	2020	14
9	A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease PLoS Genetics ·Eleonora A. Festen,Philippe Goyette,Todd J. Green,Gabrielle Boucher,Claudine Beauchamp,Gosia Trynka,P Dubois,Caroline Lagacé,Pieter Stokkers,Daan W. Hommes,Donatella Barisani,Orazio Palmieri,Vito Annese,David A. van Heel,Rinse K. Weersma,Mark J. Daly,Cisca Wijmenga,John D. Rioux	2011	162
10	Inflammatory Skin and Bowel Disease Linked toADAM17Deletion New England Journal of Medicine ·Diana C. Blaydon,Paolo Biancheri,Wei‐Li Di,Vincent Plagnol,Rita Cabral,Matthew A. Brooke,David A. van Heel,Franz Rüschendorf,Mark Toynbee,Amanda J. Walne,Edel A. O’Toole,Joanne E. Martin,Keith Lindley,Tom Vulliamy,Dominic J. Abrams,Thomas T. MacDonald,John Harper,David P. Kelsell	2011	235
11	Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection The American Journal of Human Genetics ·Alexandra Zhernakova,Clara C. Elbers,Bart Ferwerda,Jihane Romanos,Gosia Trynka,P Dubois,Carolien G. F. de Kovel,Lude Franke,Marije Oosting,Donatella Barisani,Maria Teresa Bardella,Leo A. B. Joosten,Päivi Saavalainen,David A. van Heel,Carlo Catassi,Mihai G. Netea,Cisca Wijmenga	2010	127
12	Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing Human Molecular Genetics ·Graham Heap,Jennie H. M. Yang,Kate Downes,Barry Healy,Karen A. Hunt,Nicholas Bockett,Lude Franke,P Dubois,Charles A. Mein,Richard Dobson,Thomas J. Albert,Matthew J. Rodesch,David Clayton,John A. Todd,David A. van Heel,Vincent Plagnol	2009	144
13	Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms PLoS ONE ·Alienke J. Monsuur,Paul I. W. de Bakker,Alexandra Zhernakova,Dalila Pinto,Willem Verduijn,Jihane Romanos,Renata Auricchio,Ana López,David A. van Heel,J. Bart A. Crusius,Cisca Wijmenga	2008	117
14	Selective NOD1 Agonists Cause Shock and Organ Injury/Dysfunction in Vivo American Journal of Respiratory and Critical Care Medicine ·Neil Cartwright,Oliver Murch,Shaun K. McMaster,Mark J. Paul‐Clark,David A. van Heel,Bernhard Ryffel,Valérie Quesniaux,Timothy W. Evans,Christoph Thiemermann,Jane A. Mitchell	2007	54
15	Kirsner’s Inflammatory Bowel Disease, 6th edn Gut ·David A. van Heel	2005	8
16	Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs Human Molecular Genetics ·David A. van Heel,Sheila Fisher,Andrew Kirby,Mark J. Daly,John D. Rioux,Cathryn M. Lewis	2004	184
17	Inflammatory bowel disease is associated with functional TNF polymorphism affecting OCT1/NF-kappa B interaction Gut ·David A. van Heel,Irina A. Udalova,A P De Silva,Dermot McGovern,Yoshitaka Kinouchi,J Hull,Nicholas Lench,Leonard Cardon,A H Carey,Dominik Kwiatkowski,D P Jewell	2002	1
18	Inflammatory bowel disease is associated with a functional TNF polymorphism that affects an OCT1/NF-KB transcription factor interaction Gastroenterology ·David A. van Heel,Irina A. Udalova,A P De Silva,Dermot McGovern,Yoshitaka Kinouchi,J Hull,Nicholas Lench,Leonard Cardon,A H Carey,Dominik Kwiatkowski,D P Jewell	2002	1
19	Role of NOD2 variants in spondylarthritis Queensland's institutional digital repository (The University of Queensland) ·Alison M. Crane,L Bradbury,David A. van Heel,D.P.B. McGovern,Sinéad Brophy,Lisa Rubin,Kathy Siminovitch,B P Wordsworth,A Cãlin,Brown	2002	7
20	DIABETIC NEUROPATHIC CACHEXIA: THE IMPORTANCE OF POSITIVE RECOGNITION AND EARLY NUTRITIONAL SUPPORT International Journal of Clinical Practice ·David A. van Heel,Naomi Levitt,TA Winter	1998	13

About David A. van Heel

David A. van Heel is a scholar working on Gastroenterology, Genetics and Immunology, having authored 97 papers that have together received 6.5k indexed citations. Recurring topics across this work include Inflammatory Bowel Disease (30 papers), Celiac Disease Research and Management (23 papers), Helicobacter pylori-related gastroenterology studies (18 papers), Immunodeficiency and Autoimmune Disorders (14 papers), Microscopic Colitis (12 papers), Genetic Associations and Epidemiology (11 papers), Digestive system and related health (9 papers) and Immune Response and Inflammation (8 papers). The work is most often cited by research in Gastroenterology (1.8k citations), Immunology (2.4k citations) and Genetics (2.6k citations). David A. van Heel has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Cisca Wijmenga, Karen A. Hunt, Derek P. Jewell, Matthew A. Brown, Graham Heap, Miles Parkes, Adrián Cortés, Gosia Trynka, P Dubois and Dermot McGovern. Their work appears in journals such as New England Journal of Medicine, The Lancet and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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