David A. Middleton

2.5k citations

102 papers · 2.0k indexed · h-index 26

Impact in

Spectroscopy top 2%
- Advanced NMR Techniques and Applications
Biomaterials top 5%
- Supramolecular Self-Assembly in Materials

Papers in

Spectroscopy 56
- Advanced NMR Techniques and Applications 56
Biophysics 19
- Electron Spin Resonance Studies 18

Co-authors: Jillian Madine Eleri Hughes Andrew J. Doig David G. Reid Sheena E. Radford Lu‐Yun Lian Anthony Watts Mikael Esmann
Journals: Biochemistry (9 papers)Biochemical Society Transactions (8 papers)Journal of the American Chemical Society (8 papers)Molecular Membrane Biology (6 papers)Journal of Biological Chemistry (5 papers)
Partner nations: United Kingdom Denmark United States

In The Last Decade

David A. Middleton

100 papers receiving 1.9k citations

Peers

Replace Jüri Jarvet with:

Jüri Jarvet Sweden

Philip T. F. Williamson United Kingdom

Jens Danielsson Sweden

Leonardo Gonnelli Italy

Subramanian Vivekanandan United States

Nasrollah Rezaei‐Ghaleh Germany

Anant K. Paravastu United States

Marielle Aulikki Wälti Switzerland

Michael Assfalg Italy

John H. Viles United Kingdom

David A. Middleton relative to Jüri Jarvet Sweden Jüri Jarvet's profile →

Citations per field

00.5×1.6×

Jüri Jarvet · 1×

×1.5 524/340

SPECT

×0.9 311/357

BIOMA

×1.6 114/72

BIOPH

×0.4 505/1k

PHYSI

×0.6 1k/2k

MB

Citations per year

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Countries citing papers authored by David A. Middleton

Since Specialization

Citations

This map shows the geographic impact of David A. Middleton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David A. Middleton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David A. Middleton more than expected).

Fields of papers citing papers by David A. Middleton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David A. Middleton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David A. Middleton. The network helps show where David A. Middleton may publish in the future.

Co-authors

The 25 scholars most cited alongside David A. Middleton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David A. Middleton Line = papers co-authored together David A. Middleton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	NMR studies of amyloid interactions Progress in Nuclear Magnetic Resonance Spectroscopy ·David A. Middleton	2024	4
2	Solid-state NMR chemical shift analysis for determining the conformation of ATP bound to Na,K-ATPase in its native membrane RSC Advances ·David A. Middleton, John M. Griffin, Mikael Esmann, Natalya U. Fedosova	2023	2
3	Analysis of the orientation of cholesterol in high-density lipoprotein nanodiscs using solid-state NMR Physical Chemistry Chemical Physics ·Diofanor Acevedo Correa, David A. Middleton	2022	4
4	NMR methods for structure-function investigation of membrane proteins and their ligands Journal of Labelled Compounds and Radiopharmaceuticals ·Simon G. Patching, David A. Middleton, Arnout P. Kalverda, Zhenxiang Guo, Stephen A. Baldwin, Mary K. Phillips‐Jones, Malcolm H. Levitt, Memon Bn, Peter J. F. Henderson	2012	0
5	Site‐Specific Identification of an Aβ Fibril–Heparin Interaction Site by Using Solid‐State NMR Spectroscopy Angewandte Chemie ·Jillian Madine, Maya J. Pandya, Matthew R. Hicks, Alison Rodger, Edwin A. Yates, Sheena E. Radford, David A. Middleton	2012	1
6	Probing the contacts of a low-affinity substrate with a membrane-embedded transport protein using¹H-¹³C cross-polarisation magic-angle spinning solid-state NMR Molecular Membrane Biology ·Simon G. Patching, Peter J. F. Henderson, David Sharples, David A. Middleton	2012	8
7	Comparison of aggregation enhancement and inhibition as strategies for reducing the cytotoxicity of the aortic amyloid polypeptide medin European Biophysics Journal ·Jillian Madine, David A. Middleton	2010	24
8	A study of the membrane association and regulatory effect of the phospholemman cytoplasmic domain Biochimica et Biophysica Acta (BBA) - Biomembranes ·Eleri Hughes, Sedat Arslan, Igor Barsukov, Mikael Esmann, David A. Middleton	2010	3
9	Structural analysis of uniformly 13C-labelled solids from selective angle measurements at rotational resonance Journal of Magnetic Resonance ·Simon G. Patching, R. S. Edwards, David A. Middleton	2009	3
10	Relative substrate affinities of wild-type and mutant forms of theEscherichia colisugar transporter GalP determined by solid-state NMR Molecular Membrane Biology ·Simon G. Patching, Georgios Psakis, Stephen A. Baldwin, Jocelyn M. Baldwin, Peter J. F. Henderson, David A. Middleton	2008	14
11	An NMR strategy for obtaining multiple conformational constraints for¹⁵N–¹³C spin-pair labelled organic solids Physical Chemistry Chemical Physics ·Jillian Madine, David A. Middleton	2006	6
12	Studies of the aggregation of an amyloidogenic α-synuclein peptide fragment Biochemical Society Transactions ·(unknown), Jillian Madine, Ashraf Kitmitto, David A. Middleton	2005	10
13	Reversible C–C bond formation: solid state structure of the aldol-like addition product of adamantanone to a 1,5-diazapentadienyllithium, and its solution state retro-aldol dissociationElectronic supplementary information (ESI) available: preparative and characterization details. See http://www.rsc.org/suppdata/cc/b2/b211745b/ Chemical Communications ·谢炎宋, Kifayat Huseynova, Francis S. Mair, David A. Middleton, Robin G. Pritchard	2003	11
14	A Case History: NMR Studies of the Structure of a Small Protein, ω-Conotoxin MVIIA Humana Press eBooks ·Lesley K. MacLachlan, David A. Middleton, Andrew J. Edwards, David G. Reid	2003	90
15	A solid-state NMR study of the phospholamban transmembrane domain: local structure and interactions with Ca2+-ATPase Biochimica et Biophysica Acta (BBA) - Biomembranes ·Zareen Ahmed, David G. Reid, Anthony Watts, David A. Middleton	2000	10
16	Membrane protein structure determination by solid state NMR Natural Product Reports ·Anthony Watts, Xiaoyu Zheng, Clemens Glaubitz, Gerhard Gröbner, David A. Middleton, Paul J. R. Spooner, Tatiana F. von Hertwig de Oliveira, P. O'H, Xiaoyu Zheng, Tatiana F. von Hertwig de Oliveira, P. O'H	1999	19
17	The effect of sample freezing on proton magic‐angle spinning NMR spectra of biological tissue Magnetic Resonance in Medicine ·David A. Middleton, Daniel P. Bradley, Susan C. Connor, Paul G. Mullins, David G. Reid	1998	30
18	Characterization of a small exchangeable inhibitor bound to a large membrane protein using high resolution solid state NMR spectroscopy Biophysical Journal ·David A. Middleton, Russell H. Robins, David G. Reid, M. Schmutz	1996	2
19	The conformations of a functional spin-labeled derivative of gastric H/K-ATPase investigated by EPR spectroscopy Biochemistry ·David A. Middleton, David G. Reid, Anthony Watts	1995	7
20	Membrane protein structure: the contribution and potential of novel solid state NMR approaches (Review) Molecular Membrane Biology ·Anthony Watts, Anne S. Ulrich, David A. Middleton	1995	36

About David A. Middleton

David A. Middleton is a scholar working on Spectroscopy, Biophysics, Physiology, Biomaterials and Molecular Biology, having authored 102 papers that have together received 2.0k indexed citations. Recurring topics across this work include Advanced NMR Techniques and Applications (56 papers), Alzheimer's disease research and treatments (22 papers), Protein Structure and Dynamics (18 papers), Electron Spin Resonance Studies (18 papers), Solid-state spectroscopy and crystallography (16 papers), Lipid Membrane Structure and Behavior (10 papers), Supramolecular Self-Assembly in Materials (10 papers) and Ion channel regulation and function (9 papers). The work is most often cited by research in Spectroscopy (524 citations), Biomaterials (311 citations), Biophysics (114 citations), Physiology (505 citations) and Molecular Biology (1.1k citations). David A. Middleton has collaborated with scholars based in United Kingdom, Denmark and United States. Frequent co-authors include Jillian Madine, Eleri Hughes, Andrew J. Doig, David G. Reid, Sheena E. Radford, Lu‐Yun Lian, Anthony Watts, Mikael Esmann, Peter G. Stockley and Louise C. Serpell. Their work appears in journals such as Biochemistry, Biochemical Society Transactions, Journal of the American Chemical Society, Molecular Membrane Biology and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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